Clinical trials: Processes, Metabolic
Obesity, Hypertension
The Mobile Health Platform
This study develops and pilots the initial interface of our mobile health platform that will allow for intra-individual tailoring and personalization of health interventions.
- Conditions
- Obesity, Hypertension, Diabetes
- Trial name
- mHealth (NCT02099513)
- Testing
- The Mobile Health Platform
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Duke University
Malnutrition, Diabetes
Efficacy of Zinc Fortified Fermented Wheat Flour
Zinc is a pivotal micronutrient that participates in numerous essential metabolic pathways within the human body. Its multifaceted role makes the manifestations of zinc deficiency remarkably nonspecific and age-dependent.
- Conditions
- Malnutrition, Diabetes, Inflammation, Conjunctivitis
- Trial name
- EZAFFAW (NCT06092515)
- Testing
- Fermented High Zinc Wheat Flour Flatbread, Unfermented High Zinc Wheat Flour Flatbread, Post-Harvest Fortified Whole Wheat Flour Flatbread
- Where
- Pakistan
- Volunteers
- 1,044 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Glucose Metabolism Disorders, Dehydration (Physiology)
The Effect of Water Intake on Glucose Regulation
There is a growing body of evidence suggesting low water intake and elevated levels of the hormone vasopressin exacerbate glucose regulation.
- Conditions
- Glucose Metabolism Disorders, Dehydration (Physiology), Water Deprivation
- Trial name
- INDIGO-I (NCT03765008)
- Testing
- Water intake manipulation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Arizona State University
Chronic Obstructive Pulmonary Disease
Innate Immunity in COPD
Chronic Obstructive Pulmonary Disease (COPD) causes obstruction to airflow when breathing out. It is a leading cause of chronic lung disease, hospitalization and death.
- Trial name
- NCT05743582
- Testing
- Bronchoscopy for sample collection, Blood donation
- Where
- 2 sites in United Kingdom
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Hemodyalysis, Kidney Tansplant
Assessment of Mineral and Bone Disorders in Kidney Transplant Recipients
This study aims to integrate bone measurements (including bone turnover markers (BTM), bone mineral density (BMD) measurement, vertebral fracture assessment (VFA), trabecular bone score (TBS) ) commonly used in the general…
- Conditions
- Hemodyalysis, Kidney Tansplant, Osteoporosis, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder
- Trial name
- NCT07141043
- Where
- Romania
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Chronic Kidney Diseases, Metabolic Syndrome
HAPA-based Intervention in Adults With Metabolic Syndrome and Chronic Kidney Disease
This study will adopt a 2-arm, pretest-posttest, and assessor-blind RCT design to examine the effectiveness of a theory-based health behaviour change intervention on WC (primary outcome), kidney function (eGFR, primary outcome)…
- Trial name
- NCT06715735
- Testing
- HAPA-based intervention
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Intolerance to "Conventional" Bread
Tolerance to an Artisanal Bread in a Population Intolerant of the Conventional Bread and Study of Associated Markers
The objective of this study is to evaluate the effect of consuming an "artisanal" bread for 15 days on gastrointestinal symptoms in individuals intolerant to "conventional" bread.
- Trial name
- TOLERBREAD (NCT07568223)
- Testing
- Artisanal Bread
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Obesity
Study of the Nutraceutical Properties and Health Benefits of Traditional Components of the Mediterranean Diet
The present protocol is designed to conduct nutrigenomic and nutrigenetic studies on foods conforming to the Mediterranean diet, in order to determine the effect functional foods have on blood parameters (cholesterol metabolism…
- Trial name
- NCT01890070
- Testing
- Hazelnuts, Chocolate, Red wine
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata
Eating Behavior, Obesity
Effect of mCPP on Cognitive Control, Appetite, and Neural Responses
Previous studies have reported that the 5-HT2C receptor agonist meta-chlorophenylpiperazine (mCPP) decreases appetite and food intake in humans1-3.
- Trial name
- mCPP (NCT03962829)
- Testing
- mCPP
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Cardiac Arrest, Inflammation
Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)
This is a prospective, observational study to investigate molecular mechanisms mediating the systemic inflammatory process, and changes to metabolism, and their impact on brain injury, survival, and functional outcomes after…
- Conditions
- Cardiac Arrest, Inflammation, Obesity, Hypoxic Ischemic Encephalopathy (HIE)
- Trial name
- PCAS (NCT02664831)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- MaineHealth
Heart Diseases, Type2 Diabetes
Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico
The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing…
- Conditions
- Heart Diseases, Type2 Diabetes, Hypertension, Obesity
- Trial name
- PROSPECT (NCT03794531)
- Where
- Puerto Rico
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Respiratory Distress, Hypoglycemia
Observational Study of Infants Born at 34 to 37 Weeks of Gestation Until the Age of 1 Year
Late preterm infants are at an increased risk for short and long term morbidity (during the 1st year of life, their neurodevelopmental status may also be delayed as compared to infants born at term).
- Conditions
- Respiratory Distress, Hypoglycemia, Feeding Intolerance, Jaundice
- Trial name
- NCT00550069
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Coeliac Disease
Case Finding for Coeliac Disease Using a Point of Care Test in a Pharmacy Setting
This study aims to assess whether it is feasible to use a point of care test to increase the detection of coeliac disease in a pharmacy setting.
- Trial name
- NCT02675283
- Testing
- Simtomax
- Where
- United Kingdom
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Dehydration
Effect of Different Fluid Ingestion Rate on Post-exercise Rehydration
The purpose of the present study is to investigate the effect of different rate of fluid consumption on post-exercise rehydration.
- Trial name
- NCT04155372
- Testing
- Different Fluid Ingestion Rate
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Metabolic Syndrome, HEALTHY VOLUNTEERS
Promoting Immune Health by Intermittent Fasting: a Pilot Study
The goal is to study the direct effects of long-term intermittent fasting on immune cell populations in the blood, combined with analyses of systemic metabolic fitness and inflammatory activation of leukocytes.
- Conditions
- Metabolic Syndrome, HEALTHY VOLUNTEERS, Time Restricted Feeding, Insulin Resistance
- Trial name
- TIGER (NCT05898360)
- Testing
- Time Restricted Eating, normal diet
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pulmonary Disease, Chronic Obstructive, Microbiota
The Gut-lung Axis in Chronic Obstructive Pulmonary Disease
Patients with chronic obstructive pulmonary disease (COPD) are 2-3 times more likely to occur together with chronic gastrointestinal tract (GIT) diseases, such as inflammatory bowel disease (IBD) or irritable bowel syndrome…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Microbiota, Immunity, Mucosal, Metabolism
- Trial name
- NCT03236480
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Osteoporosis, Inflammation
Effects of Increased Greek Yogurt Consumption in Senior Adults
This study aims to examine whether Greek yogurt (GY) consumption will lead to beneficial changes in bone metabolism and inflammation, in senior adults, male and female, when combined with regular exercise (senior fit classes…
- Trial name
- NCT06530394
- Testing
- Greek yogurt
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brock University
Overweight, Obesity
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study
The purpose of this study is to determine whether the combination of two dietary supplements: MUSCLE 5, which contains protein, creatine and vitamin D and TRIM 7, which contains beet extract, caffeine, coenzyme Q10, alpha lipoic…
- Trial name
- NCT05384431
- Testing
- Muscle5 and TRIM7, Mixed exercise
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Exerkine Corporation
Chronic Periodontitis, Diabetes Mellitus, Type 2
White Blood Cell Signaling and Defense Mechanisms in Patients With Diabetes Mellitus Type 2 and Periodontitis
White blood cell membrane and surface structures are affected by the metabolic disorders and complications found in diabetes mellitus.
- Trial name
- DMS (NCT01848379)
- Testing
- ADT+FD, FD
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Zentrum fuer Zahn-, Mund- und Kieferheilkunde
Healthy
Effects of Berry Peel Intake on Glucose Metabolism in Healthy Subjects
The main objective of this study is to investigate the effect of a 4-weeks intake of berry peel powder on fasting and postprandial glucose metabolism and inflammatory markers.
- Trial name
- NCT02533986
- Testing
- Berry peel drink, Control drink
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Lund University
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