Clinical trials: Procidentia
Pelvic Organ Prolapse, Urinary Incontinence
Vaginal Estradiol Use in Pessary Care
The primary outcome of this study compare the rate of pessary discontinuation at 6 months post-pessary fitting in women using vaginal estradiol versus those not using vaginal estradiol.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Pessary Ulcer of Vagina, Vaginal Atrophy
- Trial name
- NCT05458375
- Testing
- Estradiol vaginal cream
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Urinary Retention Postoperative
Effect of Phenazopyridine on Prolapse Surgery Voiding Trials
To determine if phenazopyridine reduces the rate of postoperative urinary retention after pelvic organ prolapse surgery.
- Trial name
- EPOV (NCT03065075)
- Testing
- Phenazopyridine
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Urinary Incontinence, Anal Incontinence
Pelvic Floor Muscle Training During Pregnancy
The project seeks to investigate effectiveness of PFMT during pregnancy.
- Conditions
- Urinary Incontinence, Anal Incontinence, Pelvic Organ Prolapse, Sexual Dysfunction
- Trial name
- NCT07104292
- Testing
- PFMT, Standard care
- Where
- Denmark
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Heart Murmurs, Mitral Valve Prolapse
Automated Algorithm Based Analysis of Phonocardiograms of Newborns
The purpose of this double-blind pivotal clinical utility study is to determine on a large patient population whether heart murmurs can be reliably detected with high sensitivity and specificity using a locked, automated…
- Conditions
- Heart Murmurs, Mitral Valve Prolapse, Systolic Murmurs
- Trial name
- NCT02105480
- Testing
- Computer aided auscultation (CAA)
- Where
- Austria
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- CSD Labs GmbH
Dermatochalasis, Blepharoptosis
Vibration-Assisted Anaesthesia
Aim of study is to investigate whether a small, non-invasive vibrating device applied to the forehead during local anaesthetic administration reduces the pain of the injection.
- Trial name
- NCT00793988
- Testing
- Vibration-assisted anaesthesia, Switched-off vibrating device
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Uterine Fibroids, Adenomyosis
Ovarian Reserve Modification After Lps Hysterectomy With Bilateral Salpingectomy
The aim of this RCT of study is to compare the standard TLH with adnexal preservation with TLH plus prophylactic bilateral salpingectomy (PBS) in terms of ovarian reserve and surgical outcomes
- Conditions
- Uterine Fibroids, Adenomyosis, Pelvic Pain, Pelvic Prolapse
- Trial name
- NCT02086344
- Testing
- PBS, TLH _adnexal preservation
- Where
- Italy
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Blepharoptosis
Comparison of Postoperative Pain With Two Different Types of Local Anesthesia in Surgery for a Drooping Eyelid
Conjunctival Mullerectomy is a well known procedure used to correct upper lid ptosis via a posterior approach. Patients who undergo this procedure are often given local anesthesia to alleviate intraoperative and postoperative…
- Trial name
- NCT01350024
- Testing
- Frontal nerve block with 2% lidocaine with 1:100,000 dilution of epinephrine, Subconjunctival injection of 2% lidocaine with 1:100,000 dilution with epinephrine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cystocele
Transobturator Approach for Paravaginal Repair
A new technique for Applying sutures to the white line in paravaginal repair.
- Trial name
- NCT02735772
- Testing
- transobturator approach for paravaginal repair
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Postoperative Pain, Pelvic Organ Prolapse
The Effect of Local Analgesia on Postoperative Gluteal Pain in Patients Undergoing Sacrospinous Ligament Fixation
This study will randomize patients to either receive intraoperative administration of local anesthetic and corticosteriod at time of sacrospinous ligament fixation compared to placebo to determine if intraoperative trigger point…
- Conditions
- Postoperative Pain, Pelvic Organ Prolapse, Trigger Point Injection, Sacrospinous Ligament Fixation
- Trial name
- NCT03995641
- Testing
- marcaine and kenalog
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kettering Health Network
Urinary Incontinence, Pelvic Organ Prolapse
Evaluate Women After Vaginal Surgery for Urinary Symptoms and Sexual Function
Assess the outcomes of vaginal surgeries and its impact on sexual function and urinary symptoms.
- Conditions
- Urinary Incontinence, Pelvic Organ Prolapse, Surgery
- Trial name
- NCT00376441
- Testing
- Vaginal Surgery
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Skin Scarring, Eyebrow Ptosis
Use of Botulinum Toxin A in Direct Eyebrow Lift Scar
Prospective, controlled and randomized study in which participants indicated for surgery to direct eyebrow lift will be randomized into two groups.
- Trial name
- NCT06465056
- Testing
- Botulinum toxin type A
- Where
- 2 sites in Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Lower Urinary Tract Symptoms, Stress Urinary Incontinence
Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy
The purpose of this study is to compare change in pelvic floor symptoms between patients receiving medical therapy for weight loss and surgical treatment for weight loss.
- Conditions
- Lower Urinary Tract Symptoms, Stress Urinary Incontinence, Urge Urinary Incontinence, Overactive Bladder
- Trial name
- NCT07175805
- Testing
- Bariatric Surgery, GLP1 receptor agonist
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hartford HealthCare
Uterine Prolapse
Randomized Controlled Trial Comparing Acellular Collagen Biomesh (Pelvisoft) to Polypropylene Mesh(Pelvitex) for Sacral Colpopexy
This research protocol is a randomized controlled trial. It is being done to compare and find out the relative differences between the materials, (Pelivisoft) "natural organic mesh" to poly propylene mesh (Pelvitex) "manmade…
- Trial name
- NCT00564083
- Testing
- sacral colpopexy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Pelvic Organ Prolapse
Systemic Markers of Collagen Metabolism and Vitamin C in Smokers and Non-Smokers With Pelvic Organ Prolapse
Data on smoking and POP are conflicting. In a study done by Alnaif et al, smoking was found to be associated with severe POP. The authors' proposed explanation was that smoking impairs tissue and wound healing.
- Trial name
- NCT01548105
- Testing
- Blood draw for the study participants
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Postoperative Physical Functioning
PREPARE: Perioperative REhabilitation Around Vaginal Prolapse RepAir Surgery for Recovery Enhancement
Pelvic organ prolapse is a common problem faced by millions of patients in the United States, leading to an estimated 200,000 surgeries per year.
- Trial name
- PREPARE (NCT07265973)
- Testing
- Pelvic floor Home Exercise Program, this intervention is comprised of specific exercises that are easy to complete at home
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Breast Ptosis
Evaluation of Safety and Performance of the Orbix Breast Lift System
The study is using a new breast lift system to complement a breast-lift operation. In general there will be recurrence of breast-ptosis after a correcting operation.
- Trial name
- NCT00774059
- Testing
- Breast lift system
- Where
- Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Opioid Use, Surgical Recovery
Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse
The goal of the study to see if giving a numbing medicine around the cervix (called a paracervical block) during vaginal hysterectomy with prolapse repair helps people feel less pain and need fewer strong pain medicines…
- Conditions
- Opioid Use, Surgical Recovery, Vaginal Hysterectomy, Prolapse Pelvic
- Trial name
- NCT07213635
- Testing
- Bupivacaine-epinephrine, Normal saline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pelvic Organ Prolapse
Anterior Prolapse Repair With and Without Graft Augmentation
This is a randomized control trial comparing anterior colporrhaphy with augmentation with dermal allograft (ARCUS) to anterior colporrhaphy with a suture-based repair (native tissue).
- Trial name
- ARCUS (NCT04085952)
- Testing
- dermal graft (ARCUS repliform) for anterior colporrhaphy, suture based anterior colporrhaphy
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Brow Ptosis
Photographic Assessment of Eyebrow Position and Range of Motion
Forehead and eyebrow surgery is a frequently performed cosmetic surgical procedure in which the eyebrows are raised to a more aesthetically pleasing position.
- Trial name
- NCT00347308
- Testing
- Eyebrow Position
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The New York Eye & Ear Infirmary
Pelvic Organ Prolapse
Robotic Assisted Sacral Colpopexy : A Prospective Study Assessing Outcomes With Learning Curves
The investigators scientific aims are to determine the benefits associated with the use of robotic assisted laparoscopic sacrocolpopexy surgery on women with prolapse, to define how the benefits impact the patient, physician and…
- Trial name
- NCT01535833
- Testing
- Device- Robotic sacral colpopexy
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente