Clinical trials: Progesterone
Obstetric Labor, Premature
Inflammation and Cell Maturation in Preterm Delivery Placentas - in Vitro and in Vivo Effect of Progesterone
The aim of this study is to investigate the In Vitro and In Vivo effect of progesterone on immature myeloid cells (IMC), inflammation characteristics and maturation into dendritic cells (DC).
- Trial name
- NCT03211338
- Testing
- Culture with progesterone, Culture without progesterone, Culture with growth factors
- Where
- Israel
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Preterm Premature Rupture of Membrane
Effect of Progesterone on Latent Phase Prolongation in Patients With Preterm Premature Rupture of Membranes
The aim of the study is to assess the efficacy of 17-hydroxyprogesterone caproate (17P) therapy on the latency period in pregnant women with Preterm premature rupture of membranes.
- Trial name
- NCT04807543
- Testing
- 17-hydroxyprogesterone caproate, Castor Oil
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pregnancy Complications, Pregnancy Preterm
Progesterone Levels and Pregnancy Results
The aim of this study is to evaluate the amniotic fluid and serum progesterone level and pregnancy outcome
- Conditions
- Pregnancy Complications, Pregnancy Preterm, Pregnancy Loss
- Trial name
- NCT04400149
- Testing
- amniocentesis
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Preterm Labor
Vaginal Progesterone Supplementation in the Management of Preterm Labor
This study evaluates the addition of vaginal progesterone in the management of preterm labor. Half of participants will receive vaginal progesterone, tocolysis and corticosteroid, while the other half will receive only tocolysis…
- Trial name
- NCT03202836
- Testing
- progesterone, Tocolytics, Steroids
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Preeclampsia, Preeclampsia Complications
Role of Progesterone Membrane Receptors in the Pathogenesis of Preeclampsia
Preeclampsia is a pregnancy-specific hypertensive disorder and remains a leading cause of maternal and perinatal morbidity and mortality worldwide.
- Trial name
- NCT07745036
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Samsun University
Adrenal Insufficiency
Mass Spectrometry Based Cutoffs for Cortisol After Stimulation Tests
There are two main stimulation tests used to decide if a patient has cortisol deficiency. It is the "synacthen test", were we stimulate the patient with intramuscular or intravenous synacthen ( ACTH) to see how much cortisol the…
- Trial name
- NCT02818660
- Testing
- Synachten
- Where
- Norway
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Urinary Calculus
Compare the Therapeutic Effect Treated With Tamsulosin and Progesterone After ESWL( Extra Corporeal Shock Wave Lithotripsy) in Urinary Calculus
The purpose of this study is to compare the stone clearance rate treated with different drugs after ESWL in urinary calculus,These drugs are often used in urinary calculus,such as progesterone,tamsulosin,propantheline Bromide and…
- Trial name
- NCT01010048
- Testing
- progesterone,tamsulosin,propantheline Bromide and nifedipine
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chongqing Medical University
Preterm Delivery
Prophylactic Administration of Natural Progesterone in the Prevention of Preterm Delivery in Twin Pregnancies
Twin pregnancies are at substantial increased risk of preterm delivery. Prophylactic administration of progesterone in singleton pregnancies at risk of preterm delivery has been shown to be effective in reducing the rate of such…
- Trial name
- NCT01031017
- Testing
- progesterone
- Where
- Brazil
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Preterm Delivery, Cervical Length
RCT of Progesterone to Prevent Preterm Birth in Nulliparous Women With a Short Cervix
The purpose of this study is to see if giving progesterone medication to pregnant women, who have never delivered a baby after 19 weeks of pregnancy and who have a short cervix, lowers the risk of early delivery and improves the…
- Trial name
- SCAN (NCT00439374)
- Testing
- 17 alpha-hydroxyprogesterone caproate
- Where
- 14 sites in United States
- Volunteers
- 657 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Transgender Women
Progesterone in Gender Affirming Hormone Therapy Study
This study aims to study the effects of Oral Progesterone in Transgender Women. The primary goal is to study the effect of progesterone on psychological distress and secondarily on sleep quality, breast size, quality of life and…
- Trial name
- NCT06807580
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emory University
Healthy Volunteers, Female
Progesterone and Muscle Protein Synthesis in Premenopausal Women (MP4-MPS)
The goal of this clinical trial is to learn if micronized progesterone (PROMETRIUM®) influences the muscle-building response to resistance exercise in healthy premenopausal women aged 18-30 years.
- Conditions
- Healthy Volunteers, Female, Progesterone, Premenopausal
- Trial name
- MP4 MPS (NCT07173361)
- Testing
- Micronized progesterone (oral capsules)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Preterm Labor
Adjunctive Vaginal Progesterone in Management of Preterm Labor
This study evaluates the addition of vaginal micronized progesterone effervescent to standard treatment in the treatment of preterm labor.
- Trial name
- NCT05997563
- Testing
- Micronized progesterone
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Infertility
GnRH Agonist and Progesterone Versus Progesterone Only for Luteal Phase Support in Antagonist Cycles
In-Vitro Fertilisation (IVF) is the term commonly applied to a form of treatment for infertility that involves controlled ovarian hyperstimulation, egg maturation, egg collection, fertilisation, embryo culture and finally embryo…
- Trial name
- GALA (NCT02262416)
- Testing
- leuprolide
- Where
- Australia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queensland Fertility Group
Luteal Phase Progesterone Levels
The Effect of Luteal Blood Progesterone Levels on Ongoing Pregnancy Rates
Progesterone (P4) is essential for the secretory development of endometrium and the maintenance of early pregnancy. In the luteal phase following controlled ovarian stimulation in in vitro fertilization (IVF) treatment, P4…
- Trial name
- NCT04128436
- Testing
- Taking blood samples for analyzing progesterone levels
- Where
- 3 sites in Brazil, Denmark and 1 more
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Hormonal Replacement Frozen Embryo Transfer Cycle
The Rescue of Hormonal Replacement Frozen Embryo Transfer Cycle With Low Serum Progesterone.
Frozen embryo transfer (FET) is increasingly adopted strategy in modern IVF. Among the many factors that have contributed to such change, the pursuit of an ovarian hyperstimulation syndrome free clinic has been strongly required.
- Trial name
- NCT05758064
- Testing
- Duphaston, prolutex
- Where
- 2 sites in Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- El Shatby University Hospital for Obstetrics and Gynecology
Menopause, Perimenopausal Disorder
A New Hormone Replacement Paradigm: Physiologic Restoration Study
This is a three-year, prospective, observational study looking at the benefits of rhythmically dosed, bio-identical hormones compounded in a carrier cream in 100 symptomatic peri and postmenopausal women.
- Conditions
- Menopause, Perimenopausal Disorder, Menopause Related Conditions
- Trial name
- NCT04190927
- Testing
- Compounded topical estradiol and compounded topical progesterone in a carrier cream
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Women's Hormone Network
Preterm Labor, Cervical Incompetence
Cervical Cerclage for Singleton Pregnant on Vaginal Progesterone With Progressive Cervical Length Shortening
The aim of this study is to Determine whether cerclage with vaginal progesterone will: 1. Reduce the overall spontaneous preterm birth rate. 2. Prolong pregnancy latency. 3. Improve neonatal outcome.
- Trial name
- NCT03837288
- Testing
- Cerclage
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Epilepsy
Women With Epilepsy: Pregnancy Outcomes and Deliveries
This is a three-center prospective case-control study to examine the patterns of fertility among women with epilepsy (WWE) compared to an age-matched group of women without epilepsy (WWoE).
- Trial name
- WEPOD (NCT01259310)
- Where
- 3 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Placenta Previa
Vaginal Progesterone Against a Second Attack of Antepartum Haemorrhage in Placenta Previa Women
Placenta praevia is associated with an increased risk of preterm delivery (PTD) especially if associated with bleeding and uterine contractions .
- Trial name
- NCT04725929
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Nourhan Ashraf ElSherbiny
Progesterone
Pharmacokinetics of Progesterone in Pregnancy
Pharmacokinetic analysis of 200mg vaginal progesterone suppository in women with singleton pregnancies between 18 0/7- 23 6/7 weeks' gestation
- Trial name
- PK-PiP (NCT03340701)
- Testing
- vaginal progesterone suppository
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University