Clinical trials: Prognosis
Sepsis
Differential Clinical Phenotypes Of Early CD4+ And CD8+ T-Cell Recovery And Association With 28-Day Mortality In Sepsis Patients
This is a retrospective non-interventional cohort study. Medical records of adult patients with sepsis admitted to the intensive care unit will be retrospectively reviewed.
- Trial name
- NCT07787780
- Testing
- CD4+/CD8+ T-cell dynamic recovery status
- Where
- China
- Volunteers
- 303 people
- Sponsor
- Sichuan Provincial People's Hospital
The Effect of BIS Closed-loop Target Control on Postoperative Operation
Effects of BIS Closed Loop Target Controlled Infusion on Perioperative Inflammatory Response and Prognosis of Elderly Patients Undergoing Laparoscopic Radical Gastrectomy for Gastric Cancer
The purpose of this study is to find the elderly patients with laparoscopic gastric cancer radical is suitable the BIS closed round target control level of anesthesia depth of sedation, can decrease the elderly laparoscopic…
- Trial name
- NCT05173909
- Testing
- BIS closed-loop target controlled infusion
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Zhonghua Chen,MD
Status Epilepticus
Prognosis Factors Associated With Convulsive Status Epilepticus in Adults
The aim of the study is to evaluate, prospectively, prognosis factors associated with convulsive status epilepticus (CSE) in adults hospitalized in intensive care units.
- Trial name
- NCT00318578
- Where
- 34 sites in France
- Volunteers
- 100 people
- Sponsor
- Versailles Hospital
Critical Illness, Nurse's Role
Effect of Blood Group on the Survival Status of Intensive Care Patients
The research was planned to determine the effect of different blood groups on the 90-day survival of intensive care patients who were treated and maintained for the first time in the intensive care unit.
- Conditions
- Critical Illness, Nurse's Role, Risk Factor, Prognosis
- Trial name
- NCT04460625
- Where
- Turkey (Türkiye)
- Volunteers
- 3,114 people
- Sponsor
- Zonguldak Bulent Ecevit University
Pulmonary Hypertension
Prevalence, Pathogenesis, and Prognosis of Pulmonary Hypertension in Dialysis Patients
This prospective multicenter longitudinal study aims to investigate the prevalence, pathogenesis, and prognosis of pulmonary hypertension in patients with end-stage renal disease undergoing chronic hemodialysis.
- Trial name
- NCT07563608
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
COVID-19
Host-pathogen Interactions, Immune Response, and Clinical Prognosis at COVID-19 - the CoVUm Trial
The project aims to clarify how immunity to SARS-CoV2 develops in humans and to investigate the possibility of finding patients with a particularly effective, neutralizing antibody response for future treatment.
- Trial name
- CoVUm (NCT04368013)
- Testing
- Extended sampling and procedures
- Where
- 4 sites in Sweden
- Volunteers
- 550 people
- Sponsor
- Johan Normark
Hepatitis B, Hepatocellular Carcinoma (HCC)
TAF Monotherapy Versus ETV Combined With TAF on the Efficacy and Prognosis of Immunotherapy for Hepatitis B-Related Hepatocellular Carcinoma
Study Objective: To compare the efficacy and prognosis of systemic cancer therapy between TAF monotherapy and ETV plus TAF combination therapy in patients with unresectable, advanced hepatitis-B-related hepatocellular carcinoma…
- Trial name
- NCT07253220
- Testing
- The arm will receive combination therapy (entecavir 0.5 mg once daily plus TAF 25 mg once daily); after HBV DNA becomes undetectable, the combination group will switch to TAF monotherapy., TAF monotherapy
- Volunteers
- 120 people
- Sponsor
- Sun Yat-sen University
Infertility
A Retrospective Study in Chinese Good Prognosis Patients Undergoing Assisted Reproductive Technology (ART) Treatment
This is a multicenter retrospective study in good prognosis Chinese patients. Data will be collected from infertile women who underwent first in vitro fertilization (IVF)/intra cytoplasmic sperm injection (ICSI) using a…
- Trial name
- FASSION (NCT02889380)
- Testing
- No Intervention
- Where
- 4 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Cancer, Radiotherapy
Prognosis of Patient Evaluated for Palliative Radiotherapy
Many patients with incurable cancer will receive palliative oncological treatment before their death, and radiotherapy (RT) is an important element of this.
- Trial name
- PROPER (NCT03797755)
- Testing
- palliative radiotherapy
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Tuen Mun Hospital
Sepsis
A Prospective Observational Study of Sepsis
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection and is associated with high morbidity and mortality.
- Trial name
- NCT05309889
- Testing
- no intervention
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Sepsis, Acute Respiratory Distress Syndrome
A Validation Study on a Prognostic Prediction Model for Respiratory Tract Infections
This study adopted a prospective, single-center, open-label design, aiming to evaluate the efficacy of the RTI clinical outcome prediction model in predicting clinical outcomes in subjects with acute respiratory tract infections.
- Conditions
- Sepsis, Acute Respiratory Distress Syndrome, Community Acquired Pneumonia, Transcriptome
- Trial name
- NCT07109310
- Testing
- RTImodel001
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Rectal Cancer, Prognosis
Prognostic Value of Neutrophil-to-lymphocyte Ratio (NLR) on Rectal Cancer Patients
We explored the relationship between NLR and grade 3 or higher treatment related small bowel toxicity and treatment outcome of patients with rectal cancer undergoing capecitabine and concurrent intensity modulated radiotherapy…
- Trial name
- NCT03015168
- Testing
- capecitabine and concurrent intensity modulated radiotherapy
- Where
- China
- Volunteers
- 117 people
- Sponsor
- General Hospital of Ningxia Medical University
Pulmonary Artery Sarcoma
Study for the Clinical Roadmap and Prognosis of Pulmonary Artery Sarcoma.
This is an observational study in which patients with pulmonary artery sarcoma were followed up for at least 36 months and survival was investigated.
- Trial name
- NCT06165718
- Where
- China
- Volunteers
- 120 people
- Sponsor
- China-Japan Friendship Hospital
Leukemia
Identifying Cancer Genes in in Blood and Bone Marrow Samples From Patients With Acute Myeloid Leukemia
RATIONALE: Studying samples of blood and bone marrow in the laboratory from patients with cancer may help doctors learn more about changes that occur in DNA and identify genes related to cancer.
- Trial name
- NCT00897182
- Testing
- microarray analysis, polymerase chain reaction
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Vegetative State, Minimally Conscious State
Transcranial Brain Stimulation in Vegetative State Patients
The aim of this study is to determine whether transcranial brain stimulations, such as repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), are effective in terms of EEG…
- Trial name
- NCT01820923
- Testing
- Transcranial direct current stimulation (tDCS), Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Hematologic Malignancies
Cloretazine (VNP40101M) With Hematopoietic Cell Transplantation for Hematologic Malignancies
Primary: Define the maximal tolerated dose (MTD) of VNP40401M when given with hematopoietic cell transplantation (HCT) Secondary: Describe the change in pharmacokinetic (PK) parameters with increasing doses of drug.
- Trial name
- NCT00521859
- Testing
- Cloretazine, Fludarabine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- M.D. Anderson Cancer Center
Acute Subdural Hematoma, Acquired Brain Injury
A Comparative Analysis of Prognostic Factors for Functional Outcomes in Patients With Acute Subdural Hematoma
Acute subdural hematoma (ASDH) is the most common intracranial traumatic lesion that requires surgical intervention. Although there is extensive published research on acute subdural, there remains uncertainty regarding mortality…
- Trial name
- NCT06364059
- Testing
- Decompressive craniectomy with evacuation of subdural hematoma
- Where
- Czechia
- Volunteers
- 175 people
- Sponsor
- Charles University, Czech Republic
Sepsis
Hemospec Device for the Diagnosis of Sepsis
A diagnostic devise, namely HemoSpec, had been developed that integrates clinical information, along with information on circulating protein biomarkers and the morphology of white blood cells to achieve early diagnosis of sepsis.
- Trial name
- INTELLIGENCE-1 (NCT03306186)
- Testing
- HemoSpec
- Where
- 5 sites in Greece
- Volunteers
- 183 people
- Sponsor
- University of Athens
Acute Myocardial Infarction (AMI)
Prospective Cohort Study of Aging in Patients With Acute Myocardial Infarction
This is a single-center, prospective, observational cohort study designed to investigate the association between aging-related characteristics and long-term outcomes in patients with acute myocardial infarction (AMI).
- Trial name
- NCT07705997
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The Affiliated Hospital of Hangzhou Normal University
Ovarian Cancer
The Role of Regulatory T Cell in Ovarian Cancer: Focus on Relationship Between Clinical Prognosis and Regulatory T Cell Expression
Cancer is the leading cause of mortality in our country, and ovarian cancer becomes a more and more important disease gradually in the field of gynecologic malignancies.
- Trial name
- Tregs (NCT00854282)
- Testing
- Staging surgery or debulking surgery
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital