Clinical trials: Prognostic Biomarkers
Patients
Prognostic Biomarkers of Pancreatic Cancer Based on Proteomics Techniques
In this study, we will use high-throughput proteomics techniques to search for biomarkers of post-operative prognosis of pancreatic cancer in samples of patients who have been diagnosed with pancreatic cancer through…
- Trial name
- NCT05088161
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Acute Heart Failure (AHF), Sarcopenia
Sarcopenia in Older Patients Hospitalized for Acute Heart Failure.
Acute heart failure (AHF) is the leading cause of hospitalization in people over 65, with the group with preserved ejection fraction (HFpEF) being the most closely related to aging.
- Conditions
- Acute Heart Failure (AHF), Sarcopenia, Heart Failure
- Trial name
- MUSICA (NCT07530029)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Lung Cancer (NSCLC)
Survival Analysis and Prognostic Biomarker Exploration of Postoperative Adjuvant Therapy Patterns in Patients With Non-small Cell Lung Cancer After Neoadjuvant Immunotherapy
The aim of this observational study is to investigate the survival differences among patients with non-small cell lung cancer who received different adjuvant treatments after neoadjuvant immunotherapy, and to identify the main…
- Trial name
- NCT07256002
- Testing
- PD-1 Inhibitors, Chemotherapy, PD-1 inhibitors combined with chemotherapy
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Serous Papillary Endometrial Cancer
P16 Staining as Prognostic Biomarker in Serous Papillary Endometrial Cancer
P16 is a tumor suppressor protein implicated in serous papillary endometrial carcinoma. Evidence from previous trials indicates that it may be used as a diagnostic biomarker distinguishing this disease from endometrioid…
- Trial name
- NCT01267357
- Testing
- no intervention
- Where
- Israel
- Volunteers
- 62 people
- Sponsor
- Rambam Health Care Campus
Metastatic Melanoma, Melanoma
Efficacy of First-Line Immunotherapy in Metastatic Melanoma in Slovenia and Identification of Predictive Biomarkers
This study evaluates the effectiveness of first-line immunotherapy in patients with metastatic melanoma treated at the Institute of Oncology Ljubljana in Slovenia.
- Trial name
- NCT07407166
- Testing
- Immunotherapy
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- Institute of Oncology Ljubljana
Annexin A1, Adrenal Cortex Hormones
Annexin A1 Levels in SARS-CoV-2 Infection
The present study aims to determine the clinical predictivity value of blood AnxA1 levels in patients with mild and severe/critical pneumonia induced by COVID-19 and to reveal the alterations of blood AnxA1 levels in patients…
- Trial name
- NCT04948229
- Testing
- Blood serum samples
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Kafkas University
Stable Angina, Heart Failure
Association Between Inflammatory Biomarkers in CVD Patients on Empagliflozin.
The association of novel inflammatory biomarkers with cardiovascular diseases is still obscure. The present study aimed to investigate the relationship of various inflammatory biomarkers with the existence as well as the extent…
- Trial name
- NCT05911724
- Testing
- Group I Healthy, CAD-Empagliflozin 10 mg once daily for 6 months before the beginning of the study, HF-Empagliflozin 10 mg once daily for 6 months before the beginning of the study
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Damanhour University
Peripheral Arterial Disease, Myocardial Injury
Cardiovascular Risk in Peripheral Artery Disease Patients Undergoing Endovascular Revascularisation
This study will investigate heart-related complications in patients with peripheral arterial disease (PAD) undergoing endovascular revascularization procedures to improve blood flow in the legs.
- Conditions
- Peripheral Arterial Disease, Myocardial Injury, Troponin, NT-proBNP
- Trial name
- RISK (NCT07599540)
- Where
- Slovenia
- Volunteers
- 500 people
- Sponsor
- University Medical Centre Ljubljana
Stomach Neoplasms
Screening of Small Non-coding RNAs as an Auxiliary Diagnostic Biomarker for Gastric Cancer
Gastric cancer is one of the most common malignancies of the gastrointestinal system, especially in East Asia. A host of patients are diagnosed with GC at the late stage, leading to poor patient prognosis.
- Trial name
- NCT06776835
- Testing
- Analysis of relative quantitative of small non-coding RNAs
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Nantong University
Critically Ill Patients
ICG- Livertest Versus New Biomarkers as Prognostic Markers in Critically Ill ICG- Livertest Versus New Biomarkers as Prognostic Markers in Critically Ill
ICG- Leberfunktionstest versus "neue" Biomarker als prognostischer Marker bei intensivmedizischen Patienten
- Trial name
- (Greenpep) (NCT01317381)
- Testing
- Observational
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Acute Liver Failure, Liver Cirrhosis
Indocyangreen Elimination in Cirrhosis and Acute Liver Failure
Indocyangreen (ICG)is totally biliary eliminated and corresponds to hepatocyte function and liver perfusion. The ICG-clearance will be evaluated as a prognostic marker in liver disease.
- Trial name
- NCT00245310
- Testing
- Indocyangreen (ICG) clearance
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Heidelberg University
Sepsis, Acute Respiratory Distress Syndrome
A Validation Study on a Prognostic Prediction Model for Respiratory Tract Infections
This study adopted a prospective, single-center, open-label design, aiming to evaluate the efficacy of the RTI clinical outcome prediction model in predicting clinical outcomes in subjects with acute respiratory tract infections.
- Conditions
- Sepsis, Acute Respiratory Distress Syndrome, Community Acquired Pneumonia, Transcriptome
- Trial name
- NCT07109310
- Testing
- RTImodel001
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Sepsis-induced Coagulopathy
The Diagnostic and Prognostic Value of TAT, PIC, tPAI·C and TM in Sepsis-induced Coagulopathy
In order to evaluate the diagnostic and prognostic value of thrombin-antithrombin complex（TAT）, α2-plasmin inhibitor-plasmin complex（PIC）, tissue plasminogen activator-inhibitor complex（tPAI·C） and thrombomodulin（TM） in…
- Trial name
- NCT06379126
- Testing
- Test thrombin-antithrombin complex（TAT）, α2-plasmin inhibitor-plasmin complex（PIC）, tissue plasminogen activator-inhibitor complex（tPAI·C） and thrombomodulin（TM）
- Volunteers
- 210 people
- Sponsor
- The First Hospital of Jilin University
Sepsis
Pro-adrenomedullin as a Prognostic Marker in Neonatal Sepsis
The aim of this study was to clarify the prognostic value of serum pro-Adrenomedullin level in neonatal sepsis. Eighty term and preterm neonates with sepsis were enrolled in this study.
- Trial name
- NCT01362504
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Vasculitis
Search for BIO Diagnostic and Prognostic Markers in Adult VAScularitis
To date, there are no reliable diagnostic blood markers of adult vasculitis. To date, the diagnosis of vasculitis is based on invasive procedure, biopsy of affected tissues potentially at risk of complication .
- Trial name
- BIOVAS (NCT05565885)
- Testing
- Sampling
- Where
- France
- Volunteers
- 225 people
- Sponsor
- University Hospital, Tours
Breast Cancer
Molecular Signature for Breast Cancer
The main objective of this study is to evaluate and compare the diagnostic performance of a diagnostic assistance tool for analysis of 5 prognostic and predictive markers of breast cancer (HER2, Ki67 Index, Mitoses, Estrogen…
- Trial name
- MoSi4BCa (NCT05724407)
- Testing
- Diagnostic assistance tool
- Volunteers
- 220 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cervical Cancer, Radiotherapy Side Effect
Circadian as A Prognostic Factor For Radiation Response in Cervical Cancer
The study was a Randomized Clinical Trial (RCT) or clinical trial comparing the results of radiation treatment of 2 treatment groups, i.e.
- Trial name
- NCT05511740
- Testing
- Afternoon Radiation
- Volunteers
- 71 people
- Sponsor
- Universitas Indonesia
Primary Intracerebral Hemorrhage
Biomarkers for Cognitive Decline in Intracerebral Hemorrhage
The goal of this clinical trial is to see if silent brain infarcts (SBIs), or stroke-like symptoms detectable during brain imaging, are a possible contributor to cognitive decline for patients diagnosed with spontaneous…
- Trial name
- NCT06836141
- Testing
- MRI, Blood Draw, Cognitive Test
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Rush University Medical Center
Wounds and Injuries
Long-term Outcome Related Prognostic Factor and Biomarkers of Major Trauma Database Analysis
The investigators were looking for resuscitation management, trauma mechanism, risk factors, and de novo biomarkers related to prognosis and long-term outcome for evaluating trauma patients besides injury severity score (ISS)…
- Trial name
- NCT02367768
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- National Taiwan University Hospital
Coronary Disease, Myocardial Infarction
Effects of High-dose n-3 Fatty Acids on Clinical Outcome and Serum Lipids - Omacor Following Acute Myocardial Infarction
The object of this study was to evaluate the effect of a high-dose ethylester concentrate of of n-3 fatty acids administered early after an acute myocardial infarction on subsequent cardiac events and serum lipids.The second…
- Trial name
- OFAMI (NCT01422317)
- Testing
- EPA / DHA / Alpha-Tocopherol, Corn Oil / Alpha-Tocopherol (4 mg)
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Helse Stavanger HF