Clinical trials: Prognostic Factors
Endometrial Neoplasms
POLE-END REAL LIFE: Endometrial Cancer Early Stages I-II and Advanced Stages III and IV Evaluation of POLE as a Prognostic Factor. Participants Are Women >= 18 Years Old, With the Pole Mutation
POLE-END is a non-profit, observational, retrospective and prospective study which aims to analyze the clinical course of patients with POLE-mutated endometrial cancer with evaluation of Recurrence-Free Survival (RFS), defined as…
- Trial name
- POLE-END (NCT06409039)
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Azienda Ulss 2 Marca Trevigiana
We Aim to Examine the Predictors of Sustained Complete Renal Remission in Patients With Lupus Nephritis at Sohag University Hospital
Prognostic Factors for Treatment Responses in Patients With Active Lupus Nephritis at Sohag University Hospital
Systemic lupus erythematosus (SLE) is an autoimmune disease which may give rise to multiple organ involvement because of immune complex deposits.
- Trial name
- NCT04756492
- Testing
- sandimmun
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Amyotrophic Lateral Sclerosis
A Registered Cohort Study on Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a kind of motor neuron degeneration disorder without effective therapy. This registered cohort study will provide further insights into the clinical course of ALS, and investigate…
- Trial name
- NCT04008329
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Coronary Artery Disease
Ultra-low-dose CACS in a Large Population
Radiation exposure to patients from CT for CAC scoring has steadily decreased in recent years. This is mainly achieved through lowering tube currents alongside with the introduction of iterative reconstruction algorithms which…
- Trial name
- ULDCACSLARGE (NCT03637231)
- Testing
- Ultra low-dose CTAC
- Where
- Switzerland
- Volunteers
- 301 people
- Sponsor
- University of Zurich
Melanoma (Skin)
Study of Tumor Tissue From Patients With Melanoma Treated on Clinical Trial EST-1690
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00937781
- Testing
- RNA analysis, gene expression analysis, microarray analysis
- Volunteers
- 307 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
HCC
Small and Steatotic Hepatocellular Carcinoma
Percutaneous thermoablation in an effective local curative treatment in patients with cirrhosis and HCC smaller than 3 cm in diameter (BCLC 0-A).
- Trial name
- NCT03428321
- Where
- France
- Volunteers
- 238 people
- Sponsor
- University Hospital, Montpellier
COVID-19, Quality of Life
Long-term Quality of Life and Prognostic Factors in Severe COVID-19 Patients and Their Relatives
This is a prospective cohort study with multicenter retrospective data collection (CHR Metz-Thionville, Hôpital Mercy and Hôpital Bel Air).
- Conditions
- COVID-19, Quality of Life, Posttraumatic Stress Disorder, Cognitive Impairment
- Trial name
- QUALICOVID (NCT05520047)
- Testing
- COVID19-severe Patient, family of COVID19-severe Patient
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Neurologic Dysfunction
Optic Nerve Sheath Diameter, Carotid Duplex and Transcranial Duplex as a Prognostic Factor
Optic nerve sheath diameter (ONSD) had been proved to be associated with increased intracranial pressure and can be used as one of the prognostic factors in cardiac arrest patients.
- Trial name
- NCT04510363
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Lymphoma, B-Cell, Lymphoma, Large-Cell, Diffuse
A Study of Two Associations of Rituximab and Chemotherapy, With a PET-driven Strategy, in Lymphoma
This Phase II study randomized R-ACVBP and R-CHOP as induction treatment in patients from 18 to 59 with DLBCL CD20+ lymphoma and 2 or 3 adverse prognostic factors of the age-adjusted IPI.
- Trial name
- LNH2007-3B (NCT00498043)
- Testing
- R-CHOP14 induction regimen, R-ACVBP14 induction regimen
- Where
- France
- Volunteers
- 222 people
- Sponsor
- Hospices Civils de Lyon
Colorectal Cancer
Prognostic Factors Influencing the Recurrence Rate and Survival of Patients With Colorectal Cancer: a Single Institution Experience
over the past decade colon cancer has emerged as the second most deadly and the third most common type of cancer in the world with increasing incidence in Egypt due to life style and diet change.
- Trial name
- NCT06325410
- Testing
- resection of colorectal cancer
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Zagazig University
Acute Pancreatitis
Exploration of Blood Biomarkers, Including Whole Blood Viscosity as a Prognostic Factor for Acute Pancreatitis
This study aims to evaluate the usefulness of blood viscosity as a prognostic factor in patients with acute pancreatitis. The study design is a single-arm prospective cohort observational study.
- Trial name
- NCT04553783
- Where
- South Korea
- Volunteers
- 137 people
- Sponsor
- In Seok Lee
Periodontitis, Coronary Heart Disease
Periodontitis and Coronary Heart Disease
"Atherosclerosis is an inflammatory disease". The hypothesis of an infectious burden as trigger or initiator of the inflammatory process in atherosclerosis has been extensively discussed in the past years.
- Trial name
- NCT01045070
- Where
- Germany
- Volunteers
- 960 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Preterm Infants With White Matter Damage, Preterm Infants Developing Normally
VEGF as a Prognostic Factor for White Matter Damage in Preterm Infants
We hypothesize that misexpression of vascular endothelial growth factor (VEGF) in the Cerebrospinal fluid of preterm infants can be used as a biomarker to predict the risk for developing white matter damage.
- Trial name
- NCT00564161
- Sponsor
- Hadassah Medical Organization
Renal Cell Carcinoma
Metabolomic Profiling in Renal Cell Carcinoma
Antiangiogenics are the mainstay of treatment in patients with metastatic renal cell carcinoma. Conventional clinical end-points, used to measure efficacy with chemotherapeutic agents, have not been helpful in monitoring the…
- Trial name
- NCT02001493
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Colorectal Cancer in Patients Under 50 Years of Age, Colorectal Cancer
Colorectal Cancer in Young Adults: Study of Incidence, Survival, and Prognostic Factors in Tarragona, Spain
We conducted an observational, descriptive, longitudinal and retrospective study of 59 patients under 50 years of age diagnosed with CRC in the province of Tarragona, between 2019 and 2024.
- Trial name
- CCR50 (NCT07026955)
- Testing
- colorectal cancer in patients over 50 years of age
- Where
- Spain
- Volunteers
- 59 people
- Sponsor
- HJ23
Traumatic Brain Injury, Subdural Hematoma
Outcomes of Traumatic Intracranial Hemorrhage in the Elderly
This observational study aims to describe the clinical and radiological characteristics of older adults (aged 65 years and older) who experience traumatic bleeding in the brain, also known as traumatic intracranial hemorrhage.
- Conditions
- Traumatic Brain Injury, Subdural Hematoma, Epidural Hematoma
- Trial name
- NCT07822724
- Volunteers
- 50 people
- Sponsor
- Assiut University
Frailty, Frailty At Older Adults
ASSESSMENT of FRAILTY AS a PROGNOSTIC FACTOR for MORTALITY, DISABILITY, and QUALITY of LIFE AFTER ICU ADMISSION
Between 30% and 40% of elderly patients (over 70 years old) who require hospitalization and treatment in Intensive Care Units (ICU) exhibit a state of frailty.
- Trial name
- FG-UCI (NCT06793462)
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
MELAS Syndrome, Noninsulin-dependent Diabetes Mellitus With Deafness
Mitochondrial nt3243 A>G Mutation in Taiwan
Mitochondrial diseases are multisystem disorders that present with a wide range of clinical manifestations. Mitochondrial DNA nt3243A>G mutation is one of the most common mutations seen in mitochondrial diseases.
- Trial name
- NCT02114554
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Myeloproliferative Neoplasm, Polycythemia Vera
Asian Myeloproliferative Neoplasm (MPN) Registry
This is a multinational, multicenter, prospective and retrospective, observational, cohort study of patients with myeloproliferative neoplasm.
- Conditions
- Myeloproliferative Neoplasm, Polycythemia Vera, Essential Thrombocythemia, Post-polycythemia Vera Myelofibrosis
- Trial name
- NCT05882773
- Where
- Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- The University of Hong Kong
Cholangiocarcinoma
Prognostic Factors for Survival in Patients With Cholangiocarcinoma
The objective of this retrospective study is to determine the survival rates of CCA patients based on different therapeutic approaches.
- Trial name
- NCT06369480
- Testing
- Resection/Ablation of tumor, Palliative chemotherapy, Neoadjuvant chemotherapy
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet