Clinical trials: Prognostic Model
Difficult Intubation
A Predictive Model for Difficult Intubation
Failure in airway management is one of the most common anesthesia-related morbidity and mortality. Each individual airway assessment has limitation to predict difficult intubation.
- Trial name
- NCT02944305
- Testing
- Endotracheal intubation
- Where
- Thailand
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Accidental Fall, Fall
Development of a Multivariable Prognostic PREdiction Model for 1-year Risk of FALLing in Community-dwelling Older Adults in a Non-clinical Setting
Falls in community-dwelling older adults is a frequent problem with an incidence of 30 % in over-65s and 50 % in over-80s. Incidences are expected to increase significantly in the future due to population aging.
- Trial name
- PREFALL (NCT03608709)
- Where
- 5 sites in Denmark
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Chronic Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF)
Precision Subtyping and Prognostic Study of Heart Failure Based on Multi-Omics Integration and Clinical Indicators: A Prospective Single-Center Cohort Study
This is a prospective single-center cohort study conducted at The First Affiliated Hospital of Xinjiang Medical University, aiming to enroll 400 patients with chronic heart failure (including HFrEF, HFmrEF, HFpEF) and 200 healthy…
- Conditions
- Chronic Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure With Preserved Ejection Fraction (HFPEF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)
- Trial name
- HF-MultiOmics (NCT07355088)
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Xinjiang Medical University
CMT, CMT (Charcot Marie Tooth Disease)
A Multi-omic Approach to the Identification of Novel Biomarkers in Early Charcot-Marie-Tooth 1A Disease (CMT1A)
The most common inherited neuropathy is Charcot-Marie-Tooth disease type 1A (CMT1A), caused by a duplication of the gene expressing PMP22.
- Conditions
- CMT, CMT (Charcot Marie Tooth Disease), CMT - Charcot-Marie-Tooth Disease, CMT1A
- Trial name
- CMT-MODs (NCT07476365)
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Idiopathic REM Sleep Behavior Disorder, Parkinson Disease
Predicting Parkinson's Disease Before It Strikes: A Brain Imaging Study in At-Risk Individual
This study aims to characterize neurodegeneration progression in patients with polysomnography (PSG)-confirmed longstanding idiopathic REM sleep behavior disorder (iRBD) and to develop a prognostic model for clinical evolution…
- Conditions
- Idiopathic REM Sleep Behavior Disorder, Parkinson Disease, Neurodegeneration, Prodromal Parkinson Disease
- Trial name
- iRBD (NCT07729748)
- Testing
- Multiparametric clinical, neuropsychological, PSG and MRI assessment
- Where
- 2 sites in Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Cardiac Surgery Associated - Acute Kidney Injury, CKD (Chronic Kidney Disease) Stage 5D
Incidence and Prognostic of Cardiac Surgery-Associated Acute Kidney Injury: A Spanish Multicenter Study (SCARS-AKI)
To predict the renal damage caused by cardiac surgery in patients to try to mitigate it as soon as possible
- Conditions
- Cardiac Surgery Associated - Acute Kidney Injury, CKD (Chronic Kidney Disease) Stage 5D, Acute Kidney Injury, Acute Kidney Disease
- Trial name
- SCARS-AKI (NCT07370831)
- Testing
- CARDIAC SURGERY
- Where
- Spain
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Universidad de Oviedo
Pulmonary Fibrosis, COVID-19
Diagnostic and Prognostic Model of Pulmonary Fibrosis After COVID-19 Pneumonia and Mechanism Study
The infection of COVID-19 has caused serious threat to the life and health of all mankind and increased huge economic burden. According to the current statistics, the incidence of pulmonary fibrosis after COVID-19 infection is…
- Trial name
- NCT05719038
- Testing
- observational study
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kunming Medical University
Alzheimer Disease, Late Onset, Mild Cognitive Impairment
Establish Diagnostic and Prognostic Models for Preclinical AD Patients Based on Multimodal MRI, Behavioral, Genetic, and Plasma Biomarkers
To establish the diagnostic and prognostic models that could help the preclinical identification of subjects at higher risk of clinical progression to mild cognitive impairment and dementia based on combined features of baseline…
- Conditions
- Alzheimer Disease, Late Onset, Mild Cognitive Impairment, Subjective Cognitive Decline
- Trial name
- NCT06561906
- Testing
- Multimodal magnetic resonance imaging scanning, behavioral, genetic and plasma biomarker testing
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Stroke, Acute
Establishing a Prognostic Model for Stroke Recovery
This main aim of the study is to investigate the changes in neurophysiological features after stroke, and its association with upper limb motor recovery, so as to establish a prognostic model for upper limb motor recovery after…
- Trial name
- NCT05332652
- Testing
- trancranial magnetic stimulation
- Where
- 2 sites in Singapore
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Covid19
Prognostic Models for COVID-19 Care
Approximately 20% of patients hospitalized with COVID-19 require intensive care and possibly invasive mechanical ventilation (MV).
- Trial name
- NCT04689711
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Gingival Recessions
AI-Based Prediction of Root Coverage Outcome From Intraoral Photographs
This study evaluates whether the outcome of root coverage surgery can be predicted from a preoperative intraoral photograph. Adults with Cairo RT1,RT2 or RT3 gingival recessions treated with a coronally advanced flap and a…
- Trial name
- NCT07775365
- Testing
- Coronally advanced flap with subepithelial connective tissue graft, Deep learning based prediction of root coverage outcome
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Marmara University
Head and Neck Cancer
Prediction of Outcome After Chemoradiotherapy for Head and Neck Cancer Using Functional Imaging and Tumor Biology
Despite uniform histopathological definition the response of locally advanced squamous cell carcinomas of the head and neck (HNSCC) to ionizing radiation differs greatly with locoregional recurrences burdening this patient…
- Trial name
- NCT01829646
- Testing
- functional MRI, Hypoxia gene expression profile., Functional MRI before start of treatment.
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Endometrial Cancer
Radiomics and Radiogenomics Models to Predict Molecular Integrated Risk Classes and Prognostic Factors in Endometrial Cancer.
The aim is to develop radiogenomics models to stratify patients into three main risk categories (Favorable, Intermediate, and Unfavorable) according to the ProMisE model (9) and use these models to predict the most prognostically…
- Trial name
- Romantic (NCT06279832)
- Testing
- trascriptomic profiling
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
IBD (Inflammatory Bowel Disease), Colon Cancer
Microbiota: Its Role in Chronic Inflammation, IDB and Risk of Colorectal Cancer. Evaluation of a Predictive Prognostic Model With Therapeutic Implications
The gut microbiome is emerging as a crucial factor in several intestinal diseases, contributing to the etiopathogenesis of inflammatory disorders.
- Trial name
- NCT07106463
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Messina