Clinical trials: Progression
Myopia
SEED-LVPEI Myopia Study
This randomized clinical trial study aims to investigate the efficacy of novel SEED's EDOF based mid-lens design in controlling the myopia progression in Indian children with these specific objectives: 1.
- Trial name
- SLIMS (NCT04618510)
- Testing
- SEED 1-dayPure EDOF soft contact lens, Single Vision Spectacles
- Where
- India
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- L.V. Prasad Eye Institute
Multiple System Atrophy, Parkinson's Disease
Prospective Multicenter Registry Study of Multiple System Atrophy in China
Multiple system atrophy is a rare, rapidly progressive neurodegenerative disease characterized by variable combinations of parkinsonism, cerebellar ataxia, and autonomic dysfunction.
- Conditions
- Multiple System Atrophy, Parkinson's Disease, Atypical Parkinsonism
- Trial name
- MSA Registry S (NCT07644013)
- Where
- China
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Prevention of Subclinical Atherosclerosis Progression, Prevention of Cognitive Decline
Nattokinase Atherothrombotic Prevention Study
The potential for nattokinase to "thin" blood and to reduce blood clotting by positive antithrombotic and fibrinolytic effects presents a unique opportunity to safely study such effects on cardiovascular disease and cognition.
- Trial name
- NAPS (NCT02080520)
- Testing
- Nattokinase
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Parkinson's Disease
Imaging Biomarkers of Progression of Mobility Impairment in Parkinson Disease
The purpose of this research is to evaluate changes in cholinergic brain activity over time in subjects with Parkinson disease.
- Trial name
- NCT01106976
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Myopia, Myopia, Progressive
Can Distance Center and Near Center Multifocal Contact Lenses Control Myopia Progression in Children?
Myopia has been increasing in prevalence and severity throughout the world over the last 30 years. Increasing levels of myopia are associated with increased frequency and severity of various ocular pathologies.
- Trial name
- ADPADP (NCT03519490)
- Testing
- Hybrid Contact Lens
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thomas A. Aller, OD
Positive COVID-19 by PCR
Predictors of COVID-19 Infection and Disease Progression
Clinical Picture: Symptomatic COVID-19 presents with a recognizable clinical syndrome that is predictable prior to testing. Clinical judgement remains important, particularly when interpreting negative test results; 2.
- Trial name
- Portsaiduni (NCT04484597)
- Testing
- Rt PCR
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Port Said University
Dental Caries, Dental White Spot
Effect of Light Curable Resin Modified Glass Ionomer Varnish on Non-Cavitated Proximal Carious Lesions' Progression
The standard-of-care preventive measures to stop early tooth decay from becoming worse is by fluoride application, diet counseling, and oral hygiene instructions. This standard way is not always successful.
- Trial name
- NCT03685058
- Testing
- Light curable resin modified glass ionomer varnish, standard-of-care preventive measures
- Where
- Saudi Arabia
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Type 1 Diabetes Mellitus
T1DM Clinical Onset and Progression in Paediatric Population
Diabetes Mellitus Type I is the chronic metabolic disease of childhood with the highest incidence in developed countries. Over the past 10 years the incidence of diabetes has been increased especially in immigrants children.
- Trial name
- Bioda (NCT03547440)
- Where
- 3 sites in Italy
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Blood Transfusion Complication, Wrong Blood in Tube
Proficiency Based Training to Investigate Blood Sampling Errors Including WBIT
The objective of this study is to determine the effectiveness of a Proficiency Based Progression training programme, together with evidence based individual feedback for any residual errors, which has been specifically developed…
- Conditions
- Blood Transfusion Complication, Wrong Blood in Tube, Pre Analytical Blood Sample Errors
- Trial name
- NCT03577561
- Testing
- Proficiency Based Progression Training in Phlebotomy
- Where
- Ireland
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Patrick Henn
Knee Osteoarthritis
the New Biomarker of the Knee Osteoarthritis Knee Osteoarthritis Occurrence and Progression
It was previously proved an association of TGF-β1 and PDGF-BB with the pathogenesis of osteoarthritis (OA) by experiments of OA animal models.
- Trial name
- NCT03015688
- Testing
- x-ray images
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Shihezi University
Labour;Obstructed, Progression
Intrapartum Translabial Ultrasonography Reliability
In a present study vaginal examination of the fetal head station is compared with transperineal ultrasonography evaluation of fetal head station and the ability of ultrasonography evaluation in predicting the time and mode of…
- Conditions
- Labour;Obstructed, Progression, Delivery Problem for Fetus, Ultrasound Therapy; Complications
- Trial name
- ITUSR (NCT04844437)
- Testing
- Transperineal ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Risk Factors, Renal Progression
P-cresol: Correlation With Glomerular Filtration Rate and Outcome in Chronic Kidney Disease
End-stage renal disease is a global epidemia with an estimated incidence of 7% per year and high morbidity-mortality rate. Early detection of chronic kidney disease (CKD) and intervention for CKD complication is important to…
- Conditions
- Risk Factors, Renal Progression, Death
- Trial name
- NCT00888030
- Testing
- there are no interventions currently listed for this study
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Ankylosing Spondylitis, Periodontitis
Prevalence and Progression of Periodontitis in Ankylosing Spondylitis
1. Our hypotheses on the relationship between periodontitis and AS are as follows; The prevalence of periodontitis is higher in AS patients group than that of non-AS control group Anti-TNF-α therapy would favorably affect the…
- Trial name
- NCT01750528
- Where
- South Korea
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Social Isolation, SCD
The Effects of Social Isolation and Social Interaction on the Risk of Dementia Progression and Brain Function in SCD (Subjective Cognitive Decline, SCD)
The goal of this clinical trial is to learn about the effects of social isolation and social interaction on the risk of dementia progression and brain function in SCD 1.
- Conditions
- Social Isolation, SCD, Subjective Cognitive Decline, MCI
- Trial name
- NCT06335836
- Testing
- social isolation
- Where
- China
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Cervical Intraepithelial Neoplasia
Comparison of Human Papillomavirus Integrated DNA and Messenger RNA in Cervical Neoplasia
The investigators hypothesis is HPV integration could result in expression of oncogene transcripts, and not only constitutive expression but also the level of expression will be decisive for transformation and the maintenance of…
- Trial name
- NCT02198365
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Cathay General Hospital
Hepatocellular Carcinoma
Yang Yin Fu Zheng Jie Du Therapy in HBV Associated Hepatocellular Carcinoma Based on the Platelet Count/Splenic Length-Diameter Ratio
Clinical research of Yang Yin Fu Zheng Jie Du therapy in HBV associated Hepatocellular Carcinoma based on the platelet count/splenic length-diameter ratio.The purpose of this study is to establish the efficacy evaluation system…
- Trial name
- NCT05154812
- Testing
- Yang Yin Fu Zheng Jie Du therapy, Routine medical care
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Beijing Ditan Hospital
Coronary Atheroscleroses, Coronary Angiography
Risk Factors of Intermediate Coronary Lesion Progression
Coronary intermediate lesions generally refer to lumen narrowing with diameter stenosis% (DS%) between 50% and 70% on angiography.
- Trial name
- NCT03855436
- Where
- China
- Volunteers
- 1,389 people, healthy volunteers welcome
- Sponsor
- China National Center for Cardiovascular Diseases
Myopia Progression
Prospective Research on the Intervention of Myoless2.0 Effectiveness (PRIME) in Pediatric Population
The Goal of the study is to evaluate the rate of myopia progression with open ring myopia control spectacle lens designs compared to a commercial peripheral plus myopia control spectacle lens (CML) in European children with…
- Trial name
- PRIME (NCT07394556)
- Testing
- myopia control lens
- Where
- 3 sites in Portugal, Spain and 1 more
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Indizen Optical Technologies, S.L.U.
CKD Progression
Hyperuricemia as Early Indication of CKD Progressing in Prediabetic
Chronic kidney disease (CKD) is a major global health problem, and hyperuricemia has emerged as both a consequence and a potential driver of its progression.
- Trial name
- NCT07199205
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Educational Problems
PBP vs Traditional Training: the T-REC Trial
This randomized controlled trial aims to compare the effectiveness of traditional training approach to training with the proficiency-based progression (PBP) approach for teaching the technical skills (TS) and non-technical skills…
- Trial name
- T-REC (NCT06147128)
- Testing
- Emergency scenario in a simulated setting where open conversion is necessary due to vessel injury during robotic surgery on a dry lab model
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Orsi Academy