Clinical trials: Prolapse
Sacral Colpopexy, Pelvic Organ Prolapse
Male Sexual Experience and Its Impact on Quality of Life Before and After Their Sexual Partners Undergo Polypropylene Mesh Augmented Pelvic Floor Reconstruction
The correction of the pelvic organ protrusion is aimed at restoring the pelvic floor functional status and ultimately improving the patient's quality of life.
- Trial name
- SEXQ (NCT01320631)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Pelvic Prolapse Conditions
Barriers and Enablers to Accessing Medical Care for Urinary Incontinence and Prolapse in GLobal Majority Women
This project aims to explore barriers to treatment seeking for symptoms of prolapse and urinary incontinence in women from ethnic minority/global majority background.
- Trial name
- BEAM UP & GLOW (NCT07310121)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Hernia, Cystocele
Surgical Treatment To Greater Anterior Vaginal Prolapse
A RCT study to compare traditional colporrhaphy versus polypropylene mesh in treatment of the anterior vaginal wall prolapse.
- Trial name
- Nazcatc™ (NCT00676325)
- Testing
- Surgical treatment of Anterior Vaginal Prolapse, NAZCA TC™ POP REPAIR SYSTEM ,promedon® , argentina., surgical treatment for anterior vaginal wall prolapse
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Prolapse
Affixing Polypropylene Mesh Using Barbed Suture (Quill™ Srs) During Laparoscopic Sacrocolpopexy Randomized Controlled Trial (Quill Lsc)
1.0 STUDY OBJECTIVE 1.1 PRIMARY OBJECTIVE - To compare two methods of polypropylene mesh attachment during laparoscopic sacrocolpopexy (LSC): running technique using self-anchoring 1 barbed delayed absorbable suture (Quill™ SRS…
- Trial name
- QUILL-LSC (NCT01551992)
- Testing
- Quill suture vs. Interrupted suture
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Rectocele; Female, Rectocele and Incomplete Uterine Prolapse
3D vs 2D-laparoscopy for Rectocele and Rectal Prolapse Correction: a Prospective, Randomized, Single Center Study
The aim is to compare proximate and remote results of 3D and conventional 2D laparoscopic interventions in terms of efficacy and safety in treatment of symptomatic rectocele and rectal prolapse.
- Conditions
- Rectocele; Female, Rectocele and Incomplete Uterine Prolapse, Rectocele and Complete Uterovaginal Prolapse, Rectal Prolapse
- Trial name
- LARC (NCT04817150)
- Testing
- Laparoscopic ventral mesh rectopexy
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexander Khitaryan
Vaginal Wall Prolapse
Surgical Repair of Vaginal Wall Prolapse Using Gamma Irradiated Amniotic Membrane as a Scaffold
The surgical repair of vaginal wall prolapse continues to remain one of the most difficult challenges in female pelvic floor reconstruction. The recurrence rate after standard colporrhaphy ranges from 40-60 %.
- Trial name
- NCT05355623
- Testing
- Vaginal Repair
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Behavior, Health, Behavior, Maternal
Women Lift Safely! An Intervention Study to Reduce the Risks of Heavy Lifting
The Women Lift Safely! Intervention study aims to increase safe carrying behavior to reduce health risks of heavy lifting in a rural area of Nepal (i.e. reducing weight and using safe lifting techniques).
- Conditions
- Behavior, Health, Behavior, Maternal, Work Related Stress
- Trial name
- NCT05154006
- Testing
- Information about benefits of the behavior, Instruction on how to perform a behavior, Self-efficacy
- Where
- 2 sites in Nepal
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Bern
Pelvic Organ Prolapse
Validation of Transvaginal Tactile Imaging
The purpose of this study is to validate safety and effectiveness in assessment of the female pelvic floor tissue, and, assess the ability of Vaginal Tactile Imager (VTI) to detect early prolapse conditions and characterize the…
- Trial name
- VTI-03 (NCT01491334)
- Where
- 2 sites in United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Artann Laboratories
Pelvic Organ Prolapse
Outcomes Following Vaginal Prolapse Repair and Mid Urethral Sling Trial
Pelvic organ prolapse is common among women with a prevalence that has been estimated to be as high as 30%. Prolapse may be corrected by surgery using either a vaginal or abdominal incision.
- Trial name
- OPUS (NCT00460434)
- Testing
- TVT
- Where
- 8 sites in United States
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- NICHD Pelvic Floor Disorders Network
Pain, Postoperative, Pelvic Organ Prolapse
Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery
The purpose of this randomized controlled trial is to determine whether, "ICE-T," a novel multimodal postoperative pain regimen composed of around the clock ice packs, toradol, and tylenol, has improved pain control intake…
- Trial name
- ICET (NCT03052816)
- Testing
- Ice T, Motrin/Percocet/Dilaudid for breakthrough
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Pelvic Organ Prolapse, Surgical Procedure, Unspecified
Comparison of Posterior and Anterior Approach to Sacrospinous Ligament Apical Fixation - Randomized Controlled Trial
Pelvic organ prolapse (POP) is a common problem among women. Apical prolapse (AP) is a prolapse of the uterus, or vaginal cuff, in women post hysterectomy.
- Trial name
- NCT04306250
- Testing
- Apical prolapse fixation - anterior access, Apical prolapse fixation - posterior access
- Where
- Israel
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Brow Ptosis
Photographic Assessment of Eyebrow Position and Range of Motion
Forehead and eyebrow surgery is a frequently performed cosmetic surgical procedure in which the eyebrows are raised to a more aesthetically pleasing position.
- Trial name
- NCT00347308
- Testing
- Eyebrow Position
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The New York Eye & Ear Infirmary
Skin Scarring, Eyebrow Ptosis
Use of Botulinum Toxin A in Direct Eyebrow Lift Scar
Prospective, controlled and randomized study in which participants indicated for surgery to direct eyebrow lift will be randomized into two groups.
- Trial name
- NCT06465056
- Testing
- Botulinum toxin type A
- Where
- 2 sites in Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Uterine Fibroids, Adenomyosis
Ovarian Reserve Modification After Lps Hysterectomy With Bilateral Salpingectomy
The aim of this RCT of study is to compare the standard TLH with adnexal preservation with TLH plus prophylactic bilateral salpingectomy (PBS) in terms of ovarian reserve and surgical outcomes
- Conditions
- Uterine Fibroids, Adenomyosis, Pelvic Pain, Pelvic Prolapse
- Trial name
- NCT02086344
- Testing
- PBS, TLH _adnexal preservation
- Where
- Italy
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Pelvic Organ Prolapse
Axis(TM) Solvent-dehydrate Dermal Allograft in the Treatment of Pelvic Organ Prolapse.
The goal of this study is to assess improvement in subjects who have undergone Axis Dermis, biologic mesh for pelvic organ prolapse repair. [describe participant population/health conditions].
- Trial name
- NCT06263985
- Testing
- Axis Dermis biologic mesh repair for pelvic organ prolapse
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Michigan Institution of Women's Health PC
Post-Hysterectomy Vaginal Vault Prolapse
Effects of Deep Breathing Excercises With and Without PMR on Depression & QOL in Females With Hystrectomy
To find out the Effects of deep breathing exercises with and without Progressive Muscle Relaxation Technique on depression and Quality of life in females with hysterotomy
- Trial name
- NCT05460962
- Testing
- Deep breathing excercises, Deep breathing exercises +and progressive muscle relaxation techniques
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Stress Urinary Incontinence, Genital Prolapse
Dynamic MRI of the Behaviour of Female Pelvic Floor
The purpose of this study was to test the suitability of dynamic magnetic resonance imaging for the pelvic floor floor, bladder neck and urethra in healthy volunteers, in stress incontinent patient and in women with genital…
- Trial name
- NCT00747370
- Testing
- movement of midurethra, bladder neck, cervix and rectum
- Where
- Finland
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Pelvic Organ Prolapse
Expedited Versus Restrictive: Limitations on Activity Following Surgical Treatment of Prolapse
The objective of the EVeRLAST study is to determine whether expedited resumption of postoperative activity levels is non-inferior to standard activity restrictions with respect to short-term anatomic prolapse outcomes.
- Trial name
- EVeRLAST (NCT04329715)
- Testing
- Expedited postoperative activity instructions, Standard postoperative activity restructions
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Duke University
Urinary Retention, Pelvic Organ Prolapse
Urinary Retention After Removing Urinary Catheter at 24 Hour Versus 48 Hour in Patients With Vaginal Surgery
Comparison incident of urinary retention in patients with vaginal surgery of pelvic organ prolapse, who removed urinary catheter at 24 hours versus 48 hours after surgery
- Trial name
- NCT04954443
- Testing
- Removing urinary catheter
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Buttock Ptosis
Ultherapy for Buttock Lift
Up to 24 subjects will be enrolled and treated. Enrolled subjects will receive two Ulthera® treatments, 90 days apart. Follow-up visits will occur at 90, 180, and 270 days following the last treatment.
- Trial name
- NCT02270892
- Testing
- Ulthera treatment
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc