Clinical trials: Prolapse Genital
Incontinence, Prostate Cancer
Urology Database to Evaluate Clinical Information and Improve Patient Care.
The purpose of initiating the Urology Database is to evaluate the outcomes of urology procedures and medical management to enhance the care and treatment of urology patients.
- Conditions
- Incontinence, Prostate Cancer, Interstitial Cystitis, Urinary Retention
- Trial name
- NCT00376298
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- Kenneth Peters, MD
Uterine Prolapse, Vault Prolapse, Vaginal
Pectopexy Autologous Vs Mesh
prospective comparative study describing using autologous graft for uterine- vault - cervical suspension vs mesh in treatment of apical prolapse
- Trial name
- NCT06524700
- Testing
- pectopexy mesh, pectopexy autologous
- Where
- 2 sites in Egypt, Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- Ain Shams Maternity Hospital
Genital Prolapse
Abdominal Pectopexy Versus Abdominal Sacral Hysteropexy.
This study aims to compare between abdominal pectopexy and abdominal sacral hysteropexy in terms of efficacy (assessed by POP-Q system), intra and postoperative complications.
- Trial name
- NCT04856709
- Testing
- Abdominal Pectopexy, Abdominal Sacral Hysteropexy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Uterine Prolapse
Comparison of Laparoscopic to Vaginal Surgical Repair for Uterine Prolapse
Investigators intend to conduct a prospective randomized trial to compare vaginal hysterectomy with uterosacral colposuspension to laparoscopic supracervical hysterectomy with sacrocervicopexy.
- Trial name
- NCT01594372
- Testing
- Laparoscopic supracervical hysterectomy with sacropexy, Vaginal hysterectomy with uterosacral colposuspension
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Brigham and Women's Hospital
Pelvic Organ Prolapse
Smartmesh Technology in Pelvic Floor Repair Procedures
Pelvic organ prolapse repair involves conservative treatments and surgical treatments. Conservative treatments are for patients with moderate prolapse. Treatment of symptomatic prolapse remains essentially surgical.
- Trial name
- Restorelle (NCT03098641)
- Testing
- pelvic organ prolapse repair
- Where
- 16 sites in France
- Volunteers
- 272 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Sacral Colpopexy, Pelvic Organ Prolapse
Male Sexual Experience and Its Impact on Quality of Life Before and After Their Sexual Partners Undergo Polypropylene Mesh Augmented Pelvic Floor Reconstruction
The correction of the pelvic organ protrusion is aimed at restoring the pelvic floor functional status and ultimately improving the patient's quality of life.
- Trial name
- SEXQ (NCT01320631)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Pelvic Organ Prolapse
Impact of Level III Support Procedure on Enlarged Genital Hiatus After Minimally Invasive Sacrocolpopexy
This is a randomized controlled surgical trial evaluating the use of a concomitant posterior colporrhaphy and/or perineorrhaphy at the conclusion of minimally invasive sacrocolpopexy to narrow enlarged genital hiatuses in a…
- Trial name
- MERIT (NCT04480671)
- Testing
- Level III support procedure, Minimally Invasive Sacrocolpopexy, Transperineal ultrasound of the Pelvic Floor
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- University of Pittsburgh
Cystocele, Cystocele, Midline
Continuous Stitches Versus Simple Interrupted Stitches for Anterior Colporrhaphy
The anterior vaginal wall is the segment most commonly affected by prolapse. Traditionally, anterior vaginal wall prolapse is repaired via anterior colporrhaphy (native tissue repair), which is known to have a high recurrence…
- Conditions
- Cystocele, Cystocele, Midline, Vaginal Prolapse, Prolaps Bladder
- Trial name
- NCT05449054
- Testing
- Anterior colporrhaphy
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- Medical University of Vienna
Uterus Prolapse
Laparoscopic Supracervical Hysterectomy and Sacropexy Versus Hysteropexy Study
The purpose of this study is to compare the operative, anatomic functional outcome as well as the subjective outcome of laparoscopic supracervical hysterectomy and sacropexy compared to laparoscopic hysteropexy (conserving the…
- Trial name
- HysPex (NCT02345954)
- Testing
- Laparoscopic Supracervical Hysterectomy and Sacropexy, Laparoscopic Hysteropexy
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Kantonsspital Aarau
Pelvic Organ Prolapse, Urinary Stress Incontinence
Advanced Genital Prolapse Surgery With and Without Mid Urethral Sling to Prevent Stress Urinary Incontinence
Pelvic organ prolapse (POP) is a public health problem worldwide, affecting about 30 %. It implies physical, psychological and social losses.
- Trial name
- NCT02578056
- Testing
- Midurethral sling, Genital prolapse surgery
- Where
- Brazil
- Volunteers
- 374 people
- Sponsor
- University of Sao Paulo General Hospital
Pelvic Organ Prolapse, Vaginal Prolapse
The Impact of Long-term Pessary Use on Pelvic Organ Prolapse oìduring Covid-19 Pandemic in Patients Attending Surgery
Patients aged 45 to 80 years with a clinical diagnosis of stage III and IV genital prolapse involving the anterior and/or middle compartments and candidates for surgery will be considered.
- Trial name
- NCT06234449
- Testing
- Vaginal pessary before surgery for pelvic organ prolapse
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS San Raffaele
Prolapse, Vaginal, Prolapse, Uterine
Impact of Preop Video on Patient Anxiety
To determine whether a pre-operative educational video has an impact on the anxiety of patients undergoing vaginal prolapse surgery
- Conditions
- Prolapse, Vaginal, Prolapse, Uterine, Prolapse; Female
- Trial name
- NCT05633901
- Testing
- Educational Video, Standard Counseling
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- TriHealth Inc.
Vaginal Prolapse, Cystocele
Comparative Study of Mesh Versus No Mesh in Prolapse Surgery
Hypothesis / aims of study A RCT has shown that results of prolapse repair via vaginal approach could be improved when a polypropylene mesh is used as tissue support (1).
- Trial name
- NCT00153257
- Testing
- Ugytex
- Where
- France
- Volunteers
- 162 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Genital Prolapse
Mechanism of Incontinence Before and After Genital Prolapse Surgery
Since year 2003, Glostrup/Herlev Hospital has devised a novel technique, urethral pressure reflectometry (UPR), for measurements of pressure and cross-sectional area in the female urethra.
- Trial name
- NCT02050568
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Herlev Hospital
Prolapse Genital, Anatomical Pathological Condition
The Change in Vaginal Axis on MRI After Uterus Preserving Laparoscopic Lateral Mesh Suspension
Laparoscopic lateral mesh suspension is emerged as a practical, safe and feasible alternative to sacropexy to treat female genital apical prolapse.
- Trial name
- NCT03772015
- Testing
- Magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Pelvic Organ Prolapse, Sexual Dysfunction
The Association of Pelvic Organ Prolapse Severity and Urinary Symptoms and Sexual Function
Women with pelvic organ prolapse often accompany with urinary symptoms or sexual dysfunction, and analyzing the association will be helpful to identify the indication of proper management.
- Conditions
- Pelvic Organ Prolapse, Sexual Dysfunction, Lower Urinary Tract Symptoms
- Trial name
- NCT01776580
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Vaginal Prolapse
A Randomised, Controlled Study of Bimesh, Pelvicol for Vaginal Wall Prolapse
Anterior vaginal wall prolapse is a common problem. Until now many different surgical techniques have been evaluated but so far recurrence is often still observed.
- Trial name
- NCT00442247
- Testing
- Pelvicol
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
Pelvic Organ Prolapse, Sexual Function Abnormal
Four-arm Mesh for Vaginal Stump Prolapse
To estimate the safety and efficacy of performing modified anterior transvaginal mesh surgery using polypropylene mesh for treatment of advanced urogenital prolapse after hysterectomy (stage III and IV vc Pelvic Organ Prolapse…
- Trial name
- NCT03809806
- Testing
- 4-arm polypropylene mesh surgery, The Female Sexual Function Index (FSFI) questionnaire, King Health Questionnaire (KHQ)
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- Medical University of Lublin
Genital Diseases, Female, Hysterotomy; Affecting Fetus
Effect of Salpingectomy During Conservative Hysterectomy
The study compares the effect of bilateral salpingectomy associated with conservative hysterectomy on ovarian function to the standard hysterectomy with conservation of both ovaries and tubes in terms of hormone assays, ovarian…
- Conditions
- Genital Diseases, Female, Hysterotomy; Affecting Fetus, Leiomyomata Uteri, Adenomyosis, Endometriosis
- Trial name
- SALPINGOVA (NCT01628432)
- Testing
- conservative hysterectomy I, Conservative hysterectomy II
- Where
- 7 sites in France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Tours
Pelvic Organ Prolapse, Pelvic Floor Prolapse
Laparoscopic Lateral Suspension With Mesh & Sacrocervicopexy for the Treatment of Uterine Prolapse
This study is aimed to compare the efficiency of two uterus-preserving laparoscopic methods to treat uterine prolapse in a randomized controlled trial.
- Trial name
- NCT03421457
- Testing
- Uterus-preserving laparoscopic lateral suspension with mesh, Uterus-preserving laparoscopic sacrocervicopexy with mesh
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital