Clinical trials: Prolapse Uterus
Pelvic Organ Prolapse
Risk Factors for Co-existence of Cervical Elongation in Uterine Prolapse
The presence of co-existence of cervical elongation in women of uterine prolapse may decrease the patients' satisfaction of uterine-preservation surgery for uterine prolapse, and additional surgery, such as Manchester surgery…
- Trial name
- NCT02465658
- Testing
- Medical records were reviewed.
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Prolapse Genital, Anatomical Pathological Condition
The Change in Vaginal Axis on MRI After Uterus Preserving Laparoscopic Lateral Mesh Suspension
Laparoscopic lateral mesh suspension is emerged as a practical, safe and feasible alternative to sacropexy to treat female genital apical prolapse.
- Trial name
- NCT03772015
- Testing
- Magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Uterine Prolapse
Does Doing Pelvic Floor Exercise Ease Symptoms for Women Living With Prolapse?
The purpose of this study is to investigate the feasibility of undertaking a multi-centre randomised controlled trial of the effectiveness of a pelvic floor muscle training (PFMT) intervention for women with pelvic organ prolapse.
- Trial name
- NCT00158626
- Testing
- pelvic floor muscle training
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- Glasgow Caledonian University
Visceral Prolapse
Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial Design
The study is a multi-center, randomized, surgical trial of women with symptomatic post-hysterectomy apical (cuff) prolapse desiring surgical treatment.
- Trial name
- ASPIRe (NCT02676973)
- Testing
- Open, Robotic, or Laparoscopic, Transvaginal Native Tissue Repair, Uphold™ LITE
- Where
- 10 sites in United States
- Volunteers
- 360 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Uterine Prolapse, Vault Prolapse, Vaginal
Pectopexy Autologous Vs Mesh
prospective comparative study describing using autologous graft for uterine- vault - cervical suspension vs mesh in treatment of apical prolapse
- Trial name
- NCT06524700
- Testing
- pectopexy mesh, pectopexy autologous
- Where
- 2 sites in Egypt, Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- Ain Shams Maternity Hospital
Uterine Fibroid, Uterine Bleeding
Can 3D Laparoscopy Improve Surgical Performances in Surgeons in Training?
Due to the inconclusive results on the benefits of 3D laparoscopic system present in literature, this prospective randomised pilot study aims to assess if the operative time of total laparoscopic hysterectomy (TLH) for benign…
- Conditions
- Uterine Fibroid, Uterine Bleeding, Uterine Prolapse
- Trial name
- NCT04209036
- Testing
- 0° 3D laparoscopy high-definition camera(Olympus Winter & IBE GMBH, Hamburg - Germany)
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Catholic University of the Sacred Heart
Pelvic Organ Prolapse, Pelvic Organ Prolapse Vaginal Surgery
To Explore the Surgical Outcomes and Safety of an Innovative Laparoscopic Uterine Pectopexy Technique Using Inverted T-meshes for Simultaneous Apical and Anterior Vaginal Repair.
Patients referred for pelvic reconstructive surgery frequently present with combined anterior and apical vaginal wall prolapse. Previous studies found that anterior compartment involvement is the most common and serious defect…
- Conditions
- Pelvic Organ Prolapse, Pelvic Organ Prolapse Vaginal Surgery, Pectopexy, Sacrocolpopexy
- Trial name
- NCT07411898
- Testing
- Laparoscopic pectopexy, Laparoscopic sacrocolpopexy
- Where
- Taiwan
- Volunteers
- 67 people
- Sponsor
- Chung Shan Medical University
Vaginal Prolapse
Prospective Observational Prolapse Study
The rationale of the study is to investigate the results of a prolapse treatment in adult women with a vaginal prolapse. The investigators will investigate this by taking questionnaires in women undergoing a surgical prolapse…
- Trial name
- NCT04701047
- Testing
- vaginal pessary, Vaginal prolapse surgery
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Ghent
Postmenopausal Period, Vaginal Atrophy
Treatment of Vaginal Atrophy With Low Intensity Nanosecond Neodymium Laser
The aim of study is characteristic of changes in the vaginal wall after treatment of neodymium laser radiation with a wavelength of 1064 nm.
- Conditions
- Postmenopausal Period, Vaginal Atrophy, Vaginal Prolapse
- Trial name
- NCT05335317
- Testing
- Laser Treatment, Topical hormone estriol, Сlinical blood analysis
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MeLSyTech, Ltd
Pelvic Organ Prolapse
Uphold Mesh for the Surgical Treatment of Uterine-predominant Prolapse
The primary objective of this study is to evaluate the efficacy of the UpholdTM LITE mesh over a 12 month follow up period, using a composite outcome including a good anatomical correction for both anterior and apical…
- Trial name
- NCT01559168
- Testing
- UpholdTM LITE placement
- Where
- 13 sites in France
- Volunteers
- 121 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Cholecystitis, Endometriosis
Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery
This is a two period cross-over study randomizing patients undergoing laparoscopic surgery into 2 different groups: group 1 in which patients receive "deep neuromuscular blockade" in the beginning portion of their laparoscopic…
- Conditions
- Cholecystitis, Endometriosis, Bowel Obstruction, Fibroids
- Trial name
- NCT02812186
- Testing
- Deep to Moderate NMB, Moderate to Deep NMB, Rocuronium
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Stony Brook University
Vaginal Prolapse
Pudendal Block Using Liposomal Bupivacaine vs. Standard Treatment During Sacrospinous Ligament Fixation
A pudendal nerve block is a procedure where a local anesthetic is injected where the pudendal nerve is located. This allows quick pain relief to the perineum, vulva, and vagina.
- Trial name
- NCT03664986
- Testing
- Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Atlantic Health System
Pelvic Organ Prolapse, Uterine Prolapse
Does a High BMI Affect Supervised Pelvic Floor Muscle Training for Improving Symptoms in Women With Various Stages of Pelvic Organ Prolapse?
The trial design is a quasi-experimental cohort trial that includes women referred for pelvic organ prolapse specific physiotherapy.
- Conditions
- Pelvic Organ Prolapse, Uterine Prolapse, Anterior Wall; Prolapse, Vaginal, Posterior Wall; Prolapse, Vaginal
- Trial name
- NCT04009694
- Testing
- Pelvic Floor Muscle training
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Salford
Leiomyoma, Uterine, Benign Gynecological Disease
Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy
vNOTES (vaginal natural orifice transluminal endoscopic surgery) hysterectomy is performed entirely through the vagina, with no abdominal incision.
- Conditions
- Leiomyoma, Uterine, Benign Gynecological Disease, Abnormal Uterine Bleeding (AUB), Uterine Prolapse
- Trial name
- vNOTES_NMBDIET (NCT07730970)
- Testing
- Deep Neuromuscular Blockade (NMB), Standard (moderate) neuromuscular blockade, Preoperative low-residue diet
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Colorectal Disorders, Prolapse
Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery
This prospective study aims to assess the efficacy of the OviTex 1S permanent mesh in pelvic floor surgery in comparison with the current standard polypropylene mesh.
- Conditions
- Colorectal Disorders, Prolapse, Prolapse Rectal, Prolapse Genital
- Trial name
- ProTex (NCT06430931)
- Testing
- Minimal invasive abdominal prolapse surgery using Polypropylene mesh, Minimal invasive abdominal prolapse surgery using OviTex 1S permanent mesh
- Where
- Netherlands
- Volunteers
- 184 people
- Sponsor
- Meander Medical Center
Vaginal Prolapse
Local Infiltration Analgesia With Ropivacaine in Posterior Vaginal Wall Prolapse:a Randomized, Double-Blind Study
The purpose of this study is to compare systematic local infiltration with ropivacaine or placebo in patients undergoing repair of posterior vaginal wall prolapse.
- Trial name
- NCT00769054
- Testing
- Ropivacaine, Isotonic NaCl
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Pelvic Organ Prolapse
Abdominal Sacral Hysteropexy Versus Vaginal Sacrospinous Hysteropexy
The aim of the current study is to compare abdominal sacral cervicopexy with vaginal sacrospinous cervicopexy in women with apical prolapse in terms of operative time, procedures safety and efficacy.
- Trial name
- NCT04850365
- Testing
- Hysteropexy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Vaginal Prolapse
The Use of Avaulta for Anterior Repair
Summary: Vaginal prolapse is a well-known disease and is observed in approximately 11% of all postmenopausal women and tending to increase with age.
- Trial name
- NCT00918099
- Testing
- Avaulta mesh, Anterior repair
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Zealand University Hospital
Uterine Prolapse, Urinary Stress Incontinence
A Study on the Anti-incontinent Effectiveness of the mTVM Method in POPQ Stage II-III Patients
An increasing number of specific procedures have been described for the surgical repair of pelvic organ prolapse (POP) and concomitant stress urinary incontinence (SUI).
- Conditions
- Uterine Prolapse, Urinary Stress Incontinence, Side Effects
- Trial name
- TVMvsmTVM (NCT02935803)
- Testing
- Trans-vaginal Mesh operation
- Where
- Hungary
- Volunteers
- 76 people
- Sponsor
- Szeged University
Sacral Colpopexy, Pelvic Organ Prolapse
Male Sexual Experience and Its Impact on Quality of Life Before and After Their Sexual Partners Undergo Polypropylene Mesh Augmented Pelvic Floor Reconstruction
The correction of the pelvic organ protrusion is aimed at restoring the pelvic floor functional status and ultimately improving the patient's quality of life.
- Trial name
- SEXQ (NCT01320631)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System