Clinical trials: Prolapsed Intervertebral Disc
Lumbar Disc Herniation, Instrument-assisted Soft Tissue Mobilization
The Efficacy Of Instrument-Assisted Soft Tissue Mobilization At Lumbar Region Disc Herniations
This study was carried out to investigate the effect of instrument-assisted soft tissue mobilization in patients with lomber region disc herniation.
- Trial name
- NCT04334122
- Testing
- Instrument-assisted soft tisue mobilization, Traditional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bezmialem Vakif University
Low Back Pain
Influence of Supervised Stabilization Exercises on Postural Control in Patients After Spine Surgery.
The aim of the study is to determine the impact of early rehabilitation in patients after lumbar spine surgery using microdiscectomy on balance, postural stability and foot pressure distribution.
- Trial name
- NCT05190003
- Testing
- Experimental Study
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Low Back Pain
Erector Spina Plan Block in Patients With Lumbar Disc Herniation
Erector Spina Plan Block (ESPB) is a technique used in surgical interventions, acute and chronic pain. The aim of this study was to investigate the effect of ESPB and core stabilization exercises on functionality in patients with…
- Trial name
- NCT06469905
- Testing
- Erector Spina Plan Block, Stabilization exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Firat University
Herniated Disc
Randomized Controlled Study to Assess the Efficacy of a Dietary Ingredient in Patients With Herniated Lumbar Disc Compression
The objective of the study is to evaluate the efficacy of a neuroprotective dietary supplement in patients suffering from herniated lumbar disc causing nerve root compression.
- Trial name
- NCT00405041
- Testing
- Dietary supplement GVG 2
- Where
- Israel
- Volunteers
- 79 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Lumbar Disc Herniation, Respiratory Mechanics
Pulmonary Mechanics and Cerebral Oxygenation During Prone Lumbar Disc Surgery
This prospective observational study aims to evaluate the relationship between changes in respiratory mechanics and cerebral oxygenation in adult patients undergoing elective lumbar disc surgery in the prone position under…
- Conditions
- Lumbar Disc Herniation, Respiratory Mechanics, Cerebral Oxygenation
- Trial name
- NCT07862257
- Testing
- Prone Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Diskectomy
Randomized Study of Anular Repair With the Xclose Tissue Repair System
The purpose of this study is to evaluate the benefits of anulus fibrosus repair utilizing Xclose™ compared to a discectomy without anulus fibrosus repair.
- Trial name
- NCT00760799
- Testing
- Discectomy with anular repair
- Where
- 34 sites in United States
- Volunteers
- 750 people
- Sponsor
- Anulex Technologies, Inc.
Progressive Relaxation Exercise, Hernia
Effects of Relaxation Exercises on Fear of Movement, Pain, and Quality of Life in Lumbar Disc Herniation Patients
This study evaluates whether progressive relaxation exercises can reduce fear of movement, pain, and improve quality of life in patients with lumbar disc herniation.
- Conditions
- Progressive Relaxation Exercise, Hernia, Pain, Kinesiophobia
- Trial name
- NCT07419958
- Testing
- progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Hasan Kalyoncu University
Sciatica, Lumbar Disc Herniation
Electroacupuncture for Insomnia in Patients With Chronic Sciatica Due to Lumbar Disc Herniation: a Randomized Controlled Trial
The goal of this clinical trial is to learn if electroacupuncture can improve sleep in people with chronic sciatica caused by lumbar disc herniation. It will also assess the safety of this treatment.
- Conditions
- Sciatica, Lumbar Disc Herniation, Insomnia
- Trial name
- NCT07576348
- Testing
- Electroacupuncture
- Volunteers
- 114 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Lumbar Radiculopathy
Lumbar Transforaminal Epidural Corticosteroid Injection(s) Versus Defined Physical Therapy
The purpose of this research study is to look at two of the common forms of treatment for this condition: physical therapy and epidural steroid injection.
- Trial name
- NCT01443819
- Testing
- Lumbar Transforaminal Epidural Corticosteroid Injection, Physical Therapy, Observation
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Lumbar Disc Herniation Surgery
Virtual Reality Operating Room Tour and Preoperative Anxiety in Spinal Surgery Patients Experimental: "VR Operating Room Tour" - Participants Viewed a Five-minute Virtual Reality Video of Preoperative Preparation and the Operating Room the Night Before Surgery, Facilitated by a Nurse.
This randomised controlled trial evaluated whether a nurse-facilitated virtual reality (VR) tour of the operating room reduces preoperative anxiety in adults awaiting lumbar disc herniation surgery.
- Trial name
- VROOM (NCT07778030)
- Testing
- Virtual Reality Operating Room Tour
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Zonguldak Bulent Ecevit University
Intervertebral Disc Displacement, Neck Pain
Effects of IASTM and Vibration Therapy in Cervical Disc Herniation
This study investigates the effects of instrument-assisted soft tissue mobilization (IASTM) and percussion massage therapy on pain, functional status, proprioception, and kinesiophobia in individuals with cervical disc…
- Trial name
- NCT06903000
- Testing
- a percussion massage gun, specially designed stainless-steel instruments, Conventional Exercise Group (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Emre DANSUK
Image, Body, Neck Pain
Investigation of the Effect of Motor Imagery Training in Individuals With Cervical Discogenic Pain
In this study, motor control exercises including cervical region, upper extremity and scapular region muscles will be applied routinely in individuals with chronic neck pain.
- Conditions
- Image, Body, Neck Pain, Disc Herniation
- Trial name
- NCT05999565
- Testing
- Motor Imagery Exercises, Motor Control Exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Surgical Site Infections, Lumbar Disc Herniation
The Effect of Number of Showers With 4% Chlorhexidine Gluconate on Prevention of Surgical Site Infections
Surgical site infections (SSIs) are the most common type of nosocomial infection in surgical departments. Although lumbar disc herniation (LDH), which is one of the common cases in neurosurgery, is a serious problem affecting…
- Trial name
- SSI (NCT06801275)
- Testing
- 1 shower with 4% chlorhexidine gluconate, 2 shower with 4% chlorhexidine gluconate
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Cervical Radiculopathy, Cervical Disc Herniation
Clinical Outcomes of Magnesium Sulfate in Cervical Interlaminar Epidural Steroid Injection
This single-center observational comparative cohort study evaluates clinical outcomes following two cervical interlaminar epidural steroid injection protocols used in routine care for chronic cervical radicular pain due to…
- Trial name
- NCT07788820
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Marmara University
Radiculopathy Lumbar, Radiculopathy Sacral
The Selective Intraperineural Nerve Root Block Study
Before lumbosacral decompression surgery for radicular pain, selective nerve root block(SNRB) is a common procedure to identify the responsible compressed nerve root(RCNR) and predict surgical outcomes.
- Conditions
- Radiculopathy Lumbar, Radiculopathy Sacral, Radiculopathy Multiple Sites, Herniated Disc
- Trial name
- SINRBS (NCT07531485)
- Testing
- Selective Intraperineural Nerve Root Block(SINRB), single-level lumbar decompression surgery
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xi'an Honghui Hospital
Central Sensitisation
Investigation of the Relationship Between Central Sensitization and Neuropathic Pain in Lumbar Disc Herniation
Central sensitization (CS) is as increased response to normal or sub-threshold stimuli of central nervous system and its close relationship with in many musculoskeletal diseases with chronic pain has been demonstrated in several…
- Trial name
- NCT06269068
- Testing
- Central sensitization inventory, Short form-36, Oswestry Low Back Pain Disability Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Marmara University
Lumbar Disc Herniation, Pain
The Spatiotemporal Gait Parameters in LDH Patient
The aim of this study was to assessment on the interaction of spatial and temporal gait parameters and gait asymmetry in patients with Lumbar Disc Herniation (LDH) before and 15 days after surgery.
- Trial name
- NCT04409548
- Testing
- All of the spatial and Temporal Gait parameters
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lumbar Disc Herniation, Lumbar Degenerative Disease
Multivariate Analysis and Machine Learning Model Risk Prediction of Recurrent Pain After PLIF Surgery for Degenerative Lumbar Spine Disease At Long-term Follow-up
The study was a clinical retrospective study designed to investigate risk factors for long-term recurrent pain after PLIF in patients with lumbar degenerative disease and to improve patient outcomes
- Conditions
- Lumbar Disc Herniation, Lumbar Degenerative Disease, Sarcopenia
- Trial name
- NCT06622356
- Testing
- MRI with Eovist
- Where
- China
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Hao Liu
Anesthesia, Pain, Postoperative
Effect of Erector Spinae Plane Block on Postoperative Nausea and Vomiting
This study will investigate the hypothesis that preoperative erector spinae plane (ESP) block will reduce the incidence of postoperative nausea and vomiting (PONV) in patients undergoing elective lumbar disc herniation (LDH)…
- Conditions
- Anesthesia, Pain, Postoperative, Nausea and Vomiting, Postoperative
- Trial name
- NCT06710457
- Testing
- ESP, No ESP
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Ankara City Hospital Bilkent
Cervical Disc Herniation, Cervical Degenerative Disc Disease
Effect of Topical Corticosteroids on Dysphagia in Anterior Cervical Discectomy and Fusion
The purpose of this study is to determine what effect intraoperative topical steroids have on reducing swallowing difficulty following Anterior Cervical Discectomy and Fusion surgery.
- Conditions
- Cervical Disc Herniation, Cervical Degenerative Disc Disease, Cervical Spondylotic Myelopathy, Dysphagia
- Trial name
- NCT02539394
- Testing
- Methylprednisolone Acetate, Hemostatic Matrix Kit
- Volunteers
- 128 people
- Sponsor
- Hospital for Special Surgery, New York