Clinical trials: Prolapsed Intervertebral Disc
Radiculopathy, Lumbar Disc Herniation
The Effect of Combination of Ultrasound and Flouroscopy Guidance in Caudal Epidural Injections
The primary purpose of this study is to asses the effect of caudal epidural injection guided by a combination of ultrasound and fluoroscopy on the duration of the procedure and the amount of radiation exposed during the…
- Conditions
- Radiculopathy, Lumbar Disc Herniation, Spinal Stenosis
- Trial name
- NCT05145842
- Testing
- floroscopy, ultrasound+fluoroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Lumbar Disc Herniation
Effect of Pulsed Mode Radiofrequency as a Treatment of Lumbar Disc Related Radicular Pain on Tumor Necrotic Factor α Level
Lumbar radiculopathy is a term that describes symptoms of pain, numbness, and/or weakness that radiate along the sciatic nerve from the lower back to the buttocks and leg (1).
- Trial name
- NCT05288920
- Testing
- Radiofrequency pulsed mode on dorsal root ganglion combined with transforaminal steroids injection, Transforaminal injection of Steroids alone
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Beni-Suef University
Lumbar Disc Herniation, Annular Disc Tear
A Post Marketing Surveillance Study
This study is a prospective, multi-center study to monitor the early safety and performance of one iteration of the Barricaid Anular Closure Device (ACD) - 6mm anchor width, when used as an adjunct to limited discectomy.
- Conditions
- Lumbar Disc Herniation, Annular Disc Tear, Annular Tear of Lumbar Disc
- Trial name
- 6MM (NCT03366779)
- Testing
- 6mm annular closure device
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 20 people
- Sponsor
- Intrinsic Therapeutics
Lumbar Herniated Disc
Evaluation of Minimally Invasive Microdiscectomy Versus Conventional Open Microdiscectomy For Lumbar Herniated Disc
Overall Objective: To evaluate pain and functional status of patients undergoing surgical correction for lumbar herniated disc, pre- and post-surgery, using subjective (VAS, Oswestry, PSQI, Patient Expectation), as well as…
- Trial name
- NCT00927056
- Testing
- Microdiscectomy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Nursing Care, Spine Surgery
Dependence, Frailty, and Kinesiophobia on Early Postoperative Mobilization and Self-Care Ability in Patients Undergoing Lumbar Disc Herniation Surgery
Lumbar disc herniation is a common condition that may impair physical functioning and reduce independence in activities of daily living.
- Conditions
- Nursing Care, Spine Surgery, Perioperative Care
- Trial name
- NCT07762183
- Where
- Turkey (Türkiye)
- Volunteers
- 221 people
- Sponsor
- Aydin Adnan Menderes University
Disc Herniation
Effects of Spinal Mobilization With and Without Clinical Pilates in Patients With Lumbar Disc Herniationc Herniation
Lumbar disc herniation is described by The North American Spine Society (NASS) as the confined movement of the disc material like nucleus pulposus and annulus fibrosis outside the limitations of the intervertebral disc space…
- Trial name
- NCT07912047
- Testing
- SPINAL MOBILIZATION, SPINAL MOBILIZATION + CLINICAL PILATES
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- University of Management and Technology Lahore
Lumbar Disc Herniation
The Relationship Between Lumbar Disc Herniation and Urinary Incontinence
The purpose of this research; To evaluate the relationship between low back pain and pelvic floor muscle strength, urinary incontinence, constipation and sexual dysfunction in female individuals with lumbar disc herniation.
- Trial name
- NCT06120517
- Testing
- emg- biofeedback
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Sanko University
Minimally Invasive Surgical Procedures, Disk, Herniated
Therapeutic Exercises and Educational Sessions After Microdiscectomy for Disc Herniation
The basic purpose of current research is to evaluate the comparative effectiveness of therapeutic exercises and educational sessions after microdiscectomy through Minimally Invasive Surgery for disc herniation.
- Trial name
- NCT04144452
- Testing
- Patient Education Session, Therapeutic Exercise plus educational session
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Ghurki Trust and Teaching Hospital
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Safety and Effectiveness Evaluation of Spinal Laminectomy Robot
The purpose of this clinical trial is to evaluate the effectiveness and safety of this spinal robot in assisting doctors to perform laminectomy in spinal surgery under the premise of ensuring the safety of the subjects and…
- Trial name
- NCT06593574
- Testing
- Robotic laminectomy, Traditional laminectomy
- Where
- 3 sites in China
- Volunteers
- 70 people
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniations
Detection of Bacteria in Herniated Nucleus Material in Lumbar Disc Herniations by Culture and PCR
The aim is to investigate if herniated nucleus material in lumbar disc herniations is infected with bacteria, and if so, to determine their prevalence (control group), and to determine if patients with pre-existing Modic changes…
- Trial name
- NCT02385968
- Where
- Denmark
- Volunteers
- 5 people
- Sponsor
- Spine Centre of Southern Denmark
Lumbar Disc Herniation
The Efficacy of Clinical Pilates Exercises on Individuals With Lumbar Disc Herniation
The aim of the study is to determine the effects of clinical Pilates Exercises on the level of pain, functional status, flexibility, static and dynamic endurance of the truncus muscles and quality of life in patients with lumbar…
- Trial name
- NCT03198273
- Testing
- Clinical pilates exercises, physiotherapy program
- Where
- Cyprus
- Volunteers
- 88 people
- Sponsor
- Eastern Mediterranean University
Lumbar Spine Disease, Lumbar Disc Herniation
Perioperative Local Anesthesia Block in Spine Surgery
The purpose of the this study to evaluate the feasibility, safety, and efficacy of a fluoroscopically-guided dorsal ramus block placed by the operative neurosurgeon prior to lumbosacral surgery.
- Conditions
- Lumbar Spine Disease, Lumbar Disc Herniation, Lumbar Spinal Stenosis
- Trial name
- NCT05094427
- Testing
- Preoperative fluoroscopically-guided dorsal ramus block placed by the operative neurosurgeon
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Columbia University
Trigger Point Pain, Myofascial
Trigger Point Incidence After Lumbar Disc Herniation Surgery
Our purpose is to determine the incidence of trigger points in patients who remain in a fixed position for a long time during lumbar disc herniation surgery.
- Trial name
- NCT04136197
- Testing
- Manual palpation for incidence determination
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Istanbul University - Cerrahpasa
Herniated Disc, Intervertebral Disc Displacement
Efficacy of Gabapentin or Amitriptyline to Reduce Postoperative Pain After Lumbar Laminectomy and Diskectomy
The hypothesis of this study is that Gabapentin or Amitriptyline has no role in preemptive analgesia to reduce postoperative pain after lumbar diskectomies.
- Trial name
- NCT01014520
- Testing
- Gabapentin , Amitriptyline
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Tabriz University
Displacement of Intervertebral Disc Without Myelopathy
Results of Mini-open Discectomy According to Sagittal Profile
In the normal healthy population, the sagittal alignment can be divided into four types based on the size of the sacral slope and lumbar lordosis.
- Trial name
- NCT05927662
- Testing
- lumbar discectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Lumbago, Lumbar Spinal Stenosis
Post Epidural Steroid Injection Follow-up
To determine the expected pain response timeline for patients receiving epidural steroid injections, our team plans to assess patient pain severity and degree of pain relief every 3 days for 23 days.
- Conditions
- Lumbago, Lumbar Spinal Stenosis, Lumbar Disc Herniation
- Trial name
- NCT04207606
- Testing
- Post Epidural Steroid Injection Follow-up
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University Medical Center
Low Back Pain, Low Back Pain, Mechanical
Effects of Mechanical Versus Manual Traction in the Management of Low Back Pain.
This study compared the effects of mechanical and manual traction on pain, disability and lumbar spinal curvature in patients with discogenic low back pain
- Conditions
- Low Back Pain, Low Back Pain, Mechanical, Disc Degeneration, Disc Prolapse
- Trial name
- NCT05059249
- Testing
- Hot Pack, Manual Traction, Mechanical Traction
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Pain, Nerve, Prolapsed Intervertebral Disc
Role Of Pregabalin To Decrease Postoperative Pain In Microdiscectomy
The purpose of this study is to compare the effect of pregabalin in reducing the neuropathic pain in postoperative patients who have undergone single level Microdiscectomy for prolapsed intervetebral lumbar disc.
- Trial name
- NCT04653792
- Testing
- Pregabalin 75mg
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Ziauddin University
Lumbar Herniated Disc
The Effect of Ozone Therapy for Lumbar Herniated Disc
The purpose of this study is to assess the efficacy (vs. placebo) of ozone infiltration and its effectiveness in comparison with micro discectomy in the treatment of lumbar herniated disc with criteria for surgery.
- Trial name
- NCT00566007
- Testing
- Discectomy/ micro discectomy, Ozone therapy, Oxygen therapy
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Kovacs Foundation
M-JOA Score
The Comparative Study of Full-Endoscopic Cervical Posterior Discectomy and Anterior Cervical Decompression and Fusion
Anterior cervical decompression and fusion is the standard procedure for operation of cervical disc herniations. Mobility-preserving Full-Endoscopic Cervical Posterior discectomy is the most common alternative in the case of soft…
- Trial name
- PPECD (NCT04175535)
- Testing
- Percutaneous Posterior Endoscopic Cervical Discectomy, Anterior cervical decompression and fusion
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine