Clinical trials: Prolapsed Intervertebral Disc
Back Pain Lower Back, Magnetic Therapy
High Intensity Focused Electromagnetic Therapy on Pain and Quality of Life in Patients With Lumbar Disc Prolapse
Determine whether high intensity focused electromagnetic therapy has a significant effect on pain and quality of life in patients with lumbar disc prolapse.
- Trial name
- NCT07278596
- Testing
- High intensity focused electromagnetic therapy (HIFEMT), Stabilization exercise program
- Volunteers
- 60 people
- Sponsor
- Middle East University
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Effect of Irrigation Pressure on Postoperative Complications and Surgical Field Clarity in Unilateral Biportal Endoscopic Surgery
This study is being done to find out if the height of the fluid bag and the direction of the surgical cut affect the pressure of the fluid used during unilateral biportal endoscopic (UBE) spine surgery.
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Lumbar Degenerative Disease
- Trial name
- NCT07837427
- Testing
- Unilateral Biportal Endoscopic Surgery
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fan Zhang
Lumbosacral Radiculopathy, Neuropathic Pain From Lumbosacral Radiculopathy
TFESI and Neuropathic Pain in Lumbosacral Radiculopathy
Patients with lumbosacral radiculopathy frequently experience neuropathic pain due to nerve root compression. Transforaminal epidural steroid injection (TFESI) is commonly used for pain relief in these patients.
- Conditions
- Lumbosacral Radiculopathy, Neuropathic Pain From Lumbosacral Radiculopathy, Disc Herniation With Radiculopathy
- Trial name
- NCT07799155
- Testing
- Transforaminal Epidural Steroid Injections
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Marmara University
Disk Herniated Lumbar, Physiotherapy
Supervised Physical Therapy Versus Unsupervised Home Exercise After Surgery for Lumbar Disc Herniation
This is a randomized controlled trial evaluation effect of postoperative rehabilitation after surgery for lumbar disc herniation.
- Conditions
- Disk Herniated Lumbar, Physiotherapy, Surgery
- Trial name
- NCT03505918
- Testing
- No referral for rehabilitation
- Where
- Denmark
- Volunteers
- 146 people
- Sponsor
- Spine Centre of Southern Denmark
Low Back Pain
Effectiveness of Caudal Epidural Injections in Treatment of Chronic Low Back and Lower Extremity Pain
To demonstrate clinically significant improvements or lack thereof in the caudal epidural patients with our without steroids. To evaluate differences in outcomes in patients receiving steroids compared to those patients…
- Trial name
- NCT00370799
- Testing
- Caudal epidural injection, Caudal Epidural Injection with generic Celestone, Caudal Epidural Injection with Celestone
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Pain Management Center of Paducah
Lumbar Disc Herniation
Open Discectomy Versus Microscopic Discectomy for Lumbar Disc Herniation
60 patients involved were divided into two matched groups; Group A: 30 patients were treated with conventional fenestration laminectomy and discectomy and Group B: 30 patients were treated with microdiscectomy.
- Trial name
- NCT04112485
- Testing
- Microdiscectomy
- Volunteers
- 60 people
- Sponsor
- Hawler Medical University
Cervical Disc Herniation
The Effect of Tendon Release Techniques in Patients With Cervical Disc Herniation
The goal of this clinical trial is to investigate the effect of using enhanced golgi tendon organ stimulation on symptoms in patients with cervical disc herniation.
- Trial name
- NCT06526325
- Testing
- Enhanced golgi tendon organ stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Istanbul Arel University
Lumbar Disc Disease, Lumbal Disc Herniation
Development of a Fascial Training Based Mobile Application and Investigation of Its Effectiveness in Patients With Disc Herniation
This study will compare three different groups for lumbar disc herniation. The first group will do fascia exercises via a mobile application, the second group will do fascia exercises via a home leaflet, and the third group will…
- Trial name
- Fascia-M (NCT07060235)
- Testing
- fascial exercise home brochure, Fascial exercise based mobile application, lumbal stabilizasyon home brochure
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Baskent University
Lumbar Disc Herniation Surgery, Disc Herniation
Return to Activity After Surgery for Lumbar Disc Herniation
RCT investigating postoperative activity restriction after lumbar discectomy in patients treated with annular closure.
- Trial name
- NCT07667348
- Testing
- Postoperative therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Intrinsic Therapeutics
Lumbar Degenerative Disease, Lumbar Spondylolisthesis
Perioperative Nutrition Management in Patients Undergoing Open Posterior Lumbar Surgery
Patients undergoing open posterior lumbar fusion surgery often experience postoperative gastrointestinal problems, such as bloating, constipation, and delayed passage of gas and stool, and may be at nutritional risk.
- Conditions
- Lumbar Degenerative Disease, Lumbar Spondylolisthesis, Lumbar Disc Herniation
- Trial name
- NCT07893938
- Testing
- Oral nutritional supplements (ONS), Carbohydrate loading (OCL), 'Probiotics (Bifidobacterium and Lactobacillus triple live capsules)'
- Where
- China
- Volunteers
- 90 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Lumbar Disc Herniation
Remission of Lumbar Disc Herniation by Physiotherapy
This study was conducted with the aim of determining whether or not Non surgical spinal decompression therapy was effective in remission of herniation, decreasing pain and improving functional status.
- Trial name
- NCT02699164
- Testing
- DRX 9000, Axiom Worldwide, Tampa, Florida, physiotherapy, spinal stabilization exercise
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Symptomatic Lumbar Disc Herniation, Symptomatic Grade I Lumbar Spondylolisthesis
Neurosurgery Patient Outcomes in Treating Spinal Disorders
The creation of a multi-center cooperative research group encompassing academic and community-based spinal practices . . .
- Trial name
- Neuropoint SD (NCT01220921)
- Testing
- Lumbar Discectomy, Single-level lumbar fusion
- Where
- 13 sites in United States, Canada
- Volunteers
- 198 people
- Sponsor
- Greenwich Hospital
Anesthesia, Nausea and Vomiting, Postoperative
Effect of Acupuncture on Postoperative Nausea and Vomiting
In this study, the hypothesis that bilateral acupuncture needling at the Neiguan (PC6) point during the intraoperative period, in addition to the 0.15 mg/kg dose of ondansetron (5-HT3 antagonist) frequently used for postoperative…
- Trial name
- NCT06669676
- Testing
- acupuncture, No acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Ankara City Hospital Bilkent
Lumbar Disc Herniation
Microendoscopic Discectomy Vs Transforaminal Endoscopic Lumbar Discectomy Vs Open Discectomy
In our study, a multicenter randomized controlled，single blind trial will be performed to evaluate the effectiveness and safety of these three procedures for the treatment of symptomatic lumbar disc herniation.
- Trial name
- NCT02358291
- Testing
- open discectomy, microendoscopic discectomy, transforaminal endoscopic lumbar discectomy
- Volunteers
- 240 people
- Sponsor
- Southeast University, China
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Intervertebral Disc Displacement, Intervertebral Disc Degeneration
Lumbar Disc Space Height in Young Disc Herniation and Degeneration Patients
As low back pain (LBP) imposes a heavy socioeconomic burden, early detection of pathologic intervertebral disc change in young adults holds high clinical relevance as a common structural cause of LBP.
- Conditions
- Intervertebral Disc Displacement, Intervertebral Disc Degeneration, Low Back Pain
- Trial name
- NCT02351206
- Testing
- x-ray, MRI
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Jaseng Hospital of Korean Medicine
Low Back Pain, Inflammatory Response
The Effect of Resolvins on the Resolve of Inflammatory Low Back Pain
Brief Summary: Inflammatory back pain is a chronic condition localized in the axial spine and sacroiliac joints.1 It often accompanies mechanical issues like lumbar disc herniation.
- Conditions
- Low Back Pain, Inflammatory Response, Lumbar Disc Herniation
- Trial name
- NCT06356844
- Testing
- Resolvin supplement
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University
Lumbar Disc Herniations
Detection of Bacteria in Herniated Nucleus Material in Lumbar Disc Herniations by Culture and PCR
The aim is to investigate if herniated nucleus material in lumbar disc herniations is infected with bacteria, and if so, to determine their prevalence (control group), and to determine if patients with pre-existing Modic changes…
- Trial name
- NCT02385968
- Where
- Denmark
- Volunteers
- 5 people
- Sponsor
- Spine Centre of Southern Denmark
Low Back Pain, Lumbar Disc Disease
Efficacy of Mechanical Traction and Spinal Decompression Treatments in Patients With Low Back Pain
Motorized traction and non-surgical spinal decompression treatments are relatively new treatments for which there is insufficient evidence in the literature.
- Conditions
- Low Back Pain, Lumbar Disc Disease, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT05617924
- Testing
- Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Afyonkarahisar Health Sciences University
Back Pain With Radiation, Radiculopathy
Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nuclectomy 3
This study is a First in Human, prospective, multi-center clinical study intended to collect safety and performance information for the Spinal Stabilization Technologies PerQdisc® Nucleus Replacement System and procedure…
- Conditions
- Back Pain With Radiation, Radiculopathy, Back Pain, Disc Herniation
- Trial name
- LOPAIN3 (NCT05732818)
- Testing
- PerQdisc Nucleus Replacement System
- Where
- 2 sites in Paraguay, Uzbekistan
- Volunteers
- 50 people
- Sponsor
- Spinal Stabilization Technologies