Clinical trials: Prolapsed Intervertebral Disc
Disc Herniations
EuroPainClinics® Study III (Prospective Observational Study)
In this prospective observational trial the effect of the Disc FX microinvasive therapy should be examined in (approximately 150) adult patients with low back pain.
- Trial name
- EPCSIII (NCT02461654)
- Testing
- Disc FX
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- EPC Education s.r.o.
Protruded Disk
CLARIX™ 100 & CLARIX CORD 1K for Discectomy Patients
The purpose of the study is to evaluate the efficacy of CLARIX™ 100 and CLARIX™ CORD 1K as a tissue barrier when used as an annular patch in discectomy patients with low back \& leg pain when compared to traditional discectomy…
- Trial name
- NCT03113786
- Testing
- CLARIX™100, CLARIX CORD 1K
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Amniox Medical, Inc.
Lumbar Disc Herniation
Preoperative Magnetic Resonance Imaging Abnormalities Predictive of Lumbar Herniation Recurrence
There are currently no standard criteria for evaluating the risk of recurrent disk herniation following surgical repair. This study investigated the predictive values of five presurgical imaging parameters, paraspinal muscle…
- Trial name
- NCT05246241
- Testing
- magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people
- Sponsor
- Ataturk University
Lumbar Disc Herniation
Lumbar Intervertebral Disc Herniation
The purpose of this study is to compare safety and outcomes of the following treatments of lumbar disc herniation: (1) discectomy with posterior dynamic stabilization with those of (2) discectomy alone or (3) discectomy with…
- Trial name
- LIDH (NCT02110186)
- Testing
- Dynamic Stabilization, Discectomy, Instrumentation and fusion
- Where
- China
- Volunteers
- 195 people
- Sponsor
- Third Military Medical University
Lumbar Disc Herniation
World Health Organization Disability Assessment Schedule (WHODAS-II) for Patients With Symptomatic Lumbar Disc Herniation
The main purpose of this study is to determine the measurement characteristics of WHODAS II (World Health Organization Disability Assessment Schedule), as well as to analyze its correlation with symptomatic lumbar disc herniation…
- Trial name
- NCT00480038
- Testing
- WHODAS II
- Where
- 2 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Kovacs Foundation
Disk Herniated Lumbar
Muscle Analyze In Patient With Disc Herniation
This study which was planned to investigate the factors affecting m. erector spinae (ES), m. multifidus (MF), m. psoas major (PM) and m. quadratus lumborum (QL), which stabilize the lumbar region in the case of disc herniation.
- Trial name
- NCT05245214
- Testing
- Magnetic Resonance Imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Lumbar Spine Disc Herniation, Lumbar Radiculitis
Dexamethasone Versus Depo Medrol in Lumbar Epidurals
Comparison of Dexamethasone versus Depo Medrol when used in lumbar epidural injections will be conducted on subjects that have not had previous injections or have not had an injection in the last 12 months.
- Conditions
- Lumbar Spine Disc Herniation, Lumbar Radiculitis, Lumbar Back Pain
- Trial name
- NCT01397552
- Testing
- Dexamethasone, methylprednisolone acetate
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- State University of New York - Upstate Medical University
Disc Prolapse With Radiculopathy
the Modified Reversed Contralateral Axial Rotation Position
This study aimed to investigate the effect of specific three-dimensional (3D) positions of the trunk on patients with lumbar discogenic pain with radiculopathy aiming to find a position that directly decompresses the impinged…
- Trial name
- NCT06359470
- Testing
- Positioning technique
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Noha Khaled Shoukry
Lomber Disc Herniation
Effectiveness of High Intensity Laser Therapy in Management of Lumbar Disc Herniation
Chronic lumbar radiculopathy is a multifactorial condition typically caused by lumbar disc herniation, where degenerative changes lead to nerve root compression, resulting in radiating pain, sensory disturbances, and motor…
- Trial name
- NCT07550569
- Testing
- Hiltherapy, physiotherapy
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Baskent University
Lumbar Disc Herniation With Radiculopathy, Low Back Pain (LBP)
"Effectiveness of Physical Therapy Added to Transforaminal Injection in Lumbar Radicular Pain"
The purpose of this study is to investigate whether adding conventional physical therapy modalities to transforaminal epidural steroid injection (TFESE) provides additional benefits in patients with acute radicular pain due to…
- Trial name
- NCT07467421
- Testing
- TFESE, TFESE+ CONVENTIONAL PHYSIOTHERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Training and Research Hospital
Lumbar Herniated Intervertebral Disc
Biportal Endoscopic Discectomy Versus Microdiscectomy: RCT, Non-inferiority Trial
This study is to compare the clinical outcome between the biportal endoscopic discectomy and microdiscectomy in herniated intervertebral disc of lumbar spine
- Trial name
- BESS (NCT03924700)
- Testing
- Biportal endoscopy, Microdiscectomy
- Where
- 2 sites in South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Lumbar Disc Herniation
Elongation Longitudinaux Avec Decoaption Osteo-Articulaire (ELDOA) in Lumbar Disc Protrusion
The aim of this randomized controlled trial will be to determine the effectiveness of ELDOA for treating lumbar disc protrusion.
- Trial name
- NCT04043611
- Testing
- Conservative physical therapy management, ELDOA
- Where
- Pakistan
- Volunteers
- 29 people
- Sponsor
- Riphah International University
Disc Herniation
The Effect of White Noise in Patients Undergoing Lumbar Disc Herniation Surgery
The aim of this clinical trial is to determine the effectiveness of listening to white noise on the sleep quality, comfort level, satisfaction level of patients after lumbar disc herniation surgery.
- Trial name
- NCT05687305
- Testing
- White Noise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Radiculopathy, Herniated Disk
Percutaneous Diskectomy SpineJet x Open Microdiskectomy in Treatment of Lumbar Radiculopathy
Approximately 300,000 patients undergo open surgical procedures to treat symptoms caused by disc herniation. Among the various surgical techniques practiced the percutaneous discectomy occupies its space since the first…
- Trial name
- PDOP_TLR (NCT01367860)
- Testing
- Open microdiscectomy, Percutaneous Diskectomy SpineJet
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Lumbar Vertebra Hernia
SI-6603 Versus Placebo in Patients With Lumbar Disc Herniation
The purpose of this study is to determine whether SI-6603 is effective in the treatment of lumbar disc herniation.
- Trial name
- NCT00634946
- Testing
- SI-6603
- Where
- 8 sites in Japan
- Volunteers
- 195 people
- Sponsor
- Seikagaku Corporation
Cervical Spondylosis, Degenerative Intervertebral Discs
An ACDF Multi-Center Study Using ViviGen Cellular Bone Matrix
The purpose of this post-market study is to collect data on ViviGen and how its use affects fusion rates in the cervical spine when used as additional grafting material to fill the cervical spacer.
- Conditions
- Cervical Spondylosis, Degenerative Intervertebral Discs, Herniated Disc
- Trial name
- NCT02814825
- Testing
- ViviGen
- Volunteers
- 100 people
- Sponsor
- DePuy Spine
Intervertebral Disc Disorder Lumbar With Radiculopathy, Surgical or Other Invasive Procedure on Wrong Patient
Directed Imagery Technique Applied to Patients Undergoing Lumbar Disc Herniation Surgery
The Directed Imagery technique (YIT) is a set of stories that people create by first giving relaxation exercises and then visualizing the symbols given by the practitioner.
- Conditions
- Intervertebral Disc Disorder Lumbar With Radiculopathy, Surgical or Other Invasive Procedure on Wrong Patient, Nurse-Patient Relations
- Trial name
- NCT05283291
- Testing
- Directed Imagery Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
PRP
"Platelet-Rich Plasma" Epidural Injection an Emerging Strategy in Lumbar Disc Herniation
To evaluate the efficacy of platelet-rich plasma (PRP; double-spin) in treatment of single-level lumbar herniated nucleus pulposus (HNP) in comparison to triamcinolone. RCT was conducted with 30 patients included.
- Trial name
- NCT05234840
- Testing
- platelet rich plasma, Triamcinolone
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Diskectomy, Intervertebral Disk Displacement
Cervical Spine; Movement Before and After Anterior Cervical Discectomy, With or Without a Cervical Disc Prosthesis
The purpose of this study is to find out if use of a cervical disc prosthesis in the treatment of a cervical disc herniation preserves or restores normal mobility and movement in the cervical spine.
- Trial name
- NCT00868335
- Testing
- Activ C disc prosthesis, Anterior cervical discectomy
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Lumbar Disc Herniation, Surgery
The Effect of Ney Music on Patients Undergoing Lumbar Disc Surgery
This randomized controlled study aims to investigate the effects of ney music listening, a traditional Turkish wind instrument, on pain, anxiety, sleep quality, and vital signs in patients undergoing lumbar disc herniation…
- Conditions
- Lumbar Disc Herniation, Surgery, Nurse's Role
- Trial name
- NCT07171008
- Testing
- Ney music
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Niran Çoban