Clinical trials: Prolonged Labor
Prolonged Second Stage of Labor
Use of Lubricant Gel to Shorten the Second Stage of Labor During Vaginal Delivery
This experimental study aims to evaluate whether the application of obstetric lubricant gel during vaginal delivery can significantly reduce the duration of the second stage of labor, preserve perineal integrity, and decrease the…
- Trial name
- OBY-GEL (NCT07428317)
- Testing
- Obstetric Lubricant Gel, Standard Active Management of Second Stage
- Where
- Honduras
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Preterm Labor With Preterm Delivery, Premature Rupture of Membranes Prolonged
Comparing Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor
This randomized prospective trial aimed to compare 2 prophylactic antibiotic regiment (ampicillin alone versus ampicillin plus gentamycin) in term prolonged pre-labor rupture of membrane and in preterm deliveries and examine…
- Trial name
- NCT05469984
- Testing
- Ampicillin Only Product, ampicillin plus gentamicin
- Where
- Israel
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Labor; Prolonged, Second Stage, Episiotomy Wound
The Impact of Different Skin Suture Methods in Episiotomy Repair on Healing and Pain
Episiotomy is the intentional incision of the perineum during vaginal birth in order to accelerate the active phase of labor. This study aimed to compare various skin closure techniques in episiotomy repair.
- Trial name
- NCT06379048
- Testing
- Mattress Suturing, Primary Suturing, Continuous Subcutaneous Suturing
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Labor; Prolonged, Second Stage, Delivery Problem
Maternal Position's Effect on Labor Progression in Occiput Posterior Deliveries
This is a randomized controlled experimental study to determine the effect of maternal position on the progression of labour in deliveries in which the foetus is in the occiput posterior position.
- Trial name
- NCT06928038
- Testing
- Positioned group
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Biruni University
Evidence-Based Practice, Labor; Prolonged, Second Stage
Open-glottis Pushing Technique Versus the Valsalva Pushing Technique in the Second Stage of Labor
Pushing has been discussed for decades, primarily in terms of facilitating care in the second stage of labor and maternal/fetal outcomes. Valsalva-type pushing is the pushing performed by a pregnant woman by holding her breath.
- Conditions
- Evidence-Based Practice, Labor; Prolonged, Second Stage, Labor, Fetal Acidosis Complicating Labor and Delivery
- Trial name
- NCT06210087
- Testing
- Spontaneous pushing technique
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Prolonged Labor
Prediction of Delivery Mode by Ultrasound-assessed Fetal Position in Nulliparous Women With Prolonged First Stage of Labor.
In the past years, numerous studies have been published on the use of ultrasound during labor, showing this is an effective, accurate and objective tool for the assessment of the fetal head position and station.
- Trial name
- NCT05206409
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Labor (Obstetrics)--Complications, Labor; Prolonged, First Stage
BUSCLAB - Buscopan to Prevent Slow Progress in Labor
To study the effect of Butylscopolamine Bromide on duration of the active phase of first stage of labor in first time mothers who cross the alert-line for labor dystocia, according to the WHO partograph.
- Trial name
- NCT03961165
- Testing
- Butylscopolamine Bromide 20 MG/ML, Sodium Chloride 9mg/mL
- Where
- Norway
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Prolonged Second Stage of Labor, Other Specified Trauma to Perineum and Vulva During Delivery
The Effect of Straining Techniques on Women and Newborn
Purpose: To examine the effects of straining techniques on the duration of labor, perineal trauma status and newborn apgar score. Method: This study is a randomized controlled trial.
- Conditions
- Prolonged Second Stage of Labor, Other Specified Trauma to Perineum and Vulva During Delivery, Newborn; Vitality
- Trial name
- NCT05578794
- Testing
- Straining types
- Where
- Turkey (Türkiye)
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Labor Onset and Length Abnormalities, Prolonged Labor
Quantifying the Impact of the Peanut Ball on the Duration of the Active Stage of Labor
Prolonged labor is associated with adverse maternal and fetal outcomes including infection, postpartum hemorrhage and increased NICU admission. One of the most common indications for cesarean section in the US is prolonged labor.
- Conditions
- Labor Onset and Length Abnormalities, Prolonged Labor, Labor Long, Labor; Poor
- Trial name
- NCT05489315
- Testing
- Positioning with peanut ball, Traditional positioning
- Where
- 4 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Post Date, Induction of Labor
Use of Single Versus Double Foley's Catheter in Pre-induction Cervical Ripening
Cervical ripening should be present before labor induction, which can generally be divided into two categories: pharmacological and mechanical
- Trial name
- NCT05511727
- Testing
- single versus double Foley's catheter in pre-induction cervical ripening
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Labor Long, Nulliparity
HIDRATA Study: Efficacy of a Hydration Protocol in Nulliparous Women During Labor
Aim. To evaluate the efficacy of optimizing hydration during labor in nulliparous women with respect to reducing the duration of dilation and the second stage of labor, lowering the incidence of Cesarean sections and fever, and…
- Conditions
- Labor Long, Nulliparity, Premature Rupture of Membrane, Pregnancy, Prolonged
- Trial name
- HYDRATA (NCT03607929)
- Testing
- optimal, variability
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Prolonged Second Stage of Labor
Trial of IV NTG for CD After Second Stage Arrest for the Prevention of Uterine Extension
Randomized controlled clinical trial of IV nitroglycerin at cesarean delivery for second stage arrest of descent to prevent or uterine extension at the hysterectomy site.
- Trial name
- NITRO (NCT02265965)
- Testing
- intravenous nitroglycerin
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Labor Pain, Labor; Prolonged, Second Stage
Remifentanil vs. Combined Spinal-epidural Analgesia for Labor Analgesia and Progress of Labor in Multiparous
Remifentanil may be an ideal drug for labor analgesia due to its pharmacodynamic and pharmacokinetic profile. As compared to epidural analgesia, it demonstrated satisfactory for pain relief at the beginning of labour with a…
- Conditions
- Labor Pain, Labor; Prolonged, Second Stage, Labor; Prolonged, First Stage
- Trial name
- NCT02963337
- Testing
- remifentanil, combined spinal-epidural analgesia
- Where
- Slovenia
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Prolonged Second Stage of Labor
Evaluation of Maternal Feedback to Shorten Pushing Efforts During Labor
This study will assess the ability for continuous electronic feedback to reduce the length of second stage labor and improve maternal and fetal outcomes.
- Trial name
- NCT02648867
- Testing
- Continuous Maternal Feedback
- Where
- 3 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Clinical Innovations, LLC
Prolonged First Stage Labor - Prevention
Best Partograph Action Line to Prevent Prolonged Labour
Objective: To compare active labour outcomes in nulliparous women at term supervised with a partograph with the action line placed at either 2 hours or 4 hours and to determine whether the 2-hour action line placement is better…
- Trial name
- Partograph (NCT02911272)
- Testing
- 2-hour action line on WHO modified partograph, Oxytocin, Forewater amniotomy
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- University of Benin
Obstetric and Perinatal Complications, Postpartum Hemorrhage
A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka
To evaluate the effectiveness of a First Referral Unit (FRU) Emergency Obstetric and Newborn Care (EmONC) skills and drills intervention, to estimate the appropriateness and effectiveness of referrals in intervention arm compared…
- Conditions
- Obstetric and Perinatal Complications, Postpartum Hemorrhage, Preeclampsia/Eclampsia, Obstructed/Prolonged Labor
- Trial name
- NCT01865656
- Testing
- Skills training, Emergency obstetric drills, Revised Case Sheets
- Volunteers
- 15,018 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Prolonged Labor, Healthy
Epidural Analgesia on Electrophysiological Function
Combined spinal-epidural analgesia (CSEA) is sometimes used for difficult births, but whether it contributes to postpartum pelvic muscle disorder is unclear.
- Conditions
- Prolonged Labor, Healthy, Pelvic Floor Disorders
- Trial name
- NCT02334150
- Testing
- CSEA (ropivocaine and sufentanil)
- Where
- China
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Nanjing Maternity and Child Health Care Hospital
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women in spontaneous labor with whom analgesia is maintained with a combined spinal epidural (CSE)…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982838
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Labor for Induction Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women scheduled for an induction of labor, with whom analgesia is maintained with a combined spinal…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982851
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Northwestern University