Clinical trials: Prolonged Pregnancy
Respiratory Distress Syndrome, Newborn, Respiratory Distress Syndrome in Premature Infant
Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting
The purpose of this study is to analyze the gastric fluid aspirated from the stomachs of neonates receiving routine post-delivery care to predict the need for prolonged respiratory support (>6 hours of life).
- Conditions
- Respiratory Distress Syndrome, Newborn, Respiratory Distress Syndrome in Premature Infant, Transient Tachypnea of the Newborn, Meconium Aspiration Syndrome
- Trial name
- NCT07344714
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Membrane Stripping, Cervical Ripening
The SWEEP Trial: a Randomized Controlled Trial
The purpose of this clinical trial is to determine whether serial membrane sweeping at term is more effective than no membrane sweeping in promoting spontaneous onset of labor.
- Conditions
- Membrane Stripping, Cervical Ripening, Memrane Sweeping
- Trial name
- NCT07043088
- Testing
- Membrane sweeping
- Where
- 2 sites in Denmark
- Volunteers
- 1,536 people
- Sponsor
- University of Aarhus
Sepsis, PROM, Preterm (Pregnancy)
Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates
Preterm infants are born at less than 37 weeks of pregnancy. Sometimes a break or tear in the fluid filled bag that surrounds and protects the infant during pregnancy leads to an untimely birth.
- Conditions
- Sepsis, PROM, Preterm (Pregnancy), Early-Onset Neonatal Sepsis, Preterm Premature Rupture of Membrane
- Trial name
- SAUNA (NCT06377397)
- Testing
- Antibiotics
- Where
- 9 sites in India
- Volunteers
- 1,500 people
- Sponsor
- Indian Council of Medical Research
Polycystic Ovary Syndrome
Effect of Ramadan Fasting on Ovulation and Insuline Resistance in Patients With PCOS
Polycystic ovary syndrome (PCOS) has a heterogeneous clinical presentation comprising reproductive (hyperandrogenism, menstrual irregularity, anovulation, infertility, pregnancy complications), metabolic [insulin resistance (IR)…
- Trial name
- NCT02499289
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Labor, Obstetric
Effect of Tafoxiparin to Treat Primary Slow Progress of Labor Including Prolonged Latent Phase and Labor Arrest
The study will be designed as a double-blind, placebo-controlled, parallel-group, dose-finding study with one group treated with placebo and three groups treated with tafoxiparin in three different infusion concentration levels…
- Trial name
- NCT03001193
- Testing
- DF 01, Oxytocin
- Where
- 12 sites in Denmark, Finland and 1 more
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- Dilafor AB
Posttraumatic Stress Disorder, Pregnancy
Prolonged Exposure Therapy to Treat Posttraumatic Stress Disorder in Pregnant Patients
The goal of this clinical trial is to learn if a treatment for adults with PTSD called prolonged exposure + incentives (PE+) works to treat pregnant patients.
- Trial name
- NCT06670079
- Testing
- Prolonged exposure therapy + incentives for therapy session attendance
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Vermont
Induction of Labour, Prolonged Pregnancy
Outpatient Foley Catheter for Induction of Labor in Nulliparous for Prolonged Pregnancy
15 to 20 % of nulliparous needs an induction at term. None study has evaluated Foley catheter induction at home versus expectative in this population
- Trial name
- FOLOUT (NCT02932319)
- Testing
- Foley catheter, expectative
- Where
- 5 sites in France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Prostatic Neoplasms, Urinary Bladder Neoplasms
Impacts of Different Pressure Pneumoperitoneum on Myocardial and Pulmonary Injuries After Robot-assisted Surgery
This study is aimed to determine whether low- and standard-pressure pneumoperitoneum have different impacts on troponin T（TnT) level as well as pulmonary complications after prolonged robot-assisted surgeries in the Trendelenburg…
- Trial name
- NCT02600481
- Testing
- low-pressure pneumoperitoneum, standard-pressure pneumoperitoneum
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Huadong Hospital
Acute Kidney Disease, Acute Kidney Injury
Impact of Different CRRT Modalities, Dosing Strategies, and Timing on Kidney Recovery and Prolonged Kidney Dysfunction
KARMA study is a hospital-based research study looking at how different ways of delivering kidney support therapy (CRRT) affect patients who are critically ill.
- Trial name
- KARMA (NCT07052617)
- Testing
- Continuos renal replacement therapy
- Volunteers
- 2,500 people
- Sponsor
- Croatian Society for Organ Support
Post-term Pregnancy (40 to 42 Weeks Gestation)
Does Acupuncture Therapy Reduce the Need for Labor Induction After Postdate (Week 41)
In recent years, it is accepted to induce birth at week 41 in order to reduce the risk in surplus pregnancies. It was found that after 41 weeks, there is a significant increase in pregnancy complications including meconium…
- Trial name
- NCT02392988
- Testing
- acupuncture treatment
- Where
- Israel
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Pregnancy Overdue - Week 41+6
Can Acupuncture be Used as Preparation for Induction of Labour
The purpose of the study is to evaluate whether acupuncture can be used to ripen cervix before medicinal induction of labor or even be used as method for induction, and thereby eliminating other and more potentially harmful…
- Trial name
- NCT00245752
- Testing
- acupuncture
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital Skejby
Abortion, Spontaneous, Abortion, Habitual
RPL: Interval to Live Birth and Adverse Perinatal Outcomes
This will be a retrospective observational cohort study utilizing the data from the British Columbia Perinatal Data Registry (BCPDR).
- Conditions
- Abortion, Spontaneous, Abortion, Habitual, Birth Intervals, Pregnancy Loss
- Trial name
- NCT04360564
- Testing
- Recurrent pregnancy loss
- Where
- Canada
- Volunteers
- 140,000 people, healthy volunteers welcome
- Sponsor
- Children's & Women's Health Centre of British Columbia
Cervical Ripening
Cervical Ripening With Misoprostol vs Isosorbide Mononitrate ; A Parallel -Arm Randomized Controlled Trial
This randomized controlled trial compared misoprostol and isosorbide mononitrate (IMN) for cervical ripening in prolonged pregnancies.
- Trial name
- NCT07121634
- Testing
- Misoprostol 25 µg Vaginal, Isosorbide Mononitrate
- Where
- Iraq
- Volunteers
- 80 people
- Sponsor
- Raid M. Al-Ani
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Labor for Induction Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women scheduled for an induction of labor, with whom analgesia is maintained with a combined spinal…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982851
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pregnancy, Labor
Study to Assess Safety and Efficacy of DF01 in Reducing Prolonged Labor
The study is a Proof-of-concept study to evaluate if DF01 can prevent protracted labor. Time to delivery will be measured from the time of at least 3 cm cervix dilatation and 3 contractions of minimum one minute's duration/10…
- Trial name
- NCT00710242
- Testing
- DF01
- Where
- 18 sites in Sweden
- Volunteers
- 263 people
- Sponsor
- Dilafor AB
Cervical Cancer, Endometrial Cancer
Fondaparinux in Preventing Blood Clots in Patients Undergoing Surgery for Gynecologic Cancer
RATIONALE: Fondaparinux may help prevent blood clots from forming in patients who are undergoing surgery for gynecologic cancer.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer
- Trial name
- NCT00381888
- Testing
- fondaparinux sodium
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Prolonged Second Stage of Labor, Prolonged Second Stage of Labor Due to Poor Maternal Effort
Vacuum Delivery in All-fours Position vs Traditional Position
The aim of the study is to investigate the safety, clinical efficacy and the maternal/neonatal outcomes of vacuum application in all-fours position compared with supine traditional position, in women undergoing vacuum-assisted…
- Trial name
- VaDe-4 (NCT05612321)
- Testing
- Vacuum application
- Volunteers
- 250 people
- Sponsor
- Ospedale degli Infermi di Biella
Pregnancy, Prolonged, Induced; Birth
Membrane Sweeping to Prevent Post-term Pregnancy: The MILO Study
Multicentre, pragmatic, parallel group, pilot randomised controlled trial with an embedded factorial design.
- Conditions
- Pregnancy, Prolonged, Induced; Birth, Pregnancy Related
- Trial name
- MILO (NCT04307199)
- Testing
- Amniotic membrane sweep
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Birth Control, Contraception
Effects of a Progestin on Frequent and/or Prolonged Bleeding With Nexplanon™
Effects of norethindrone acetate (NTA) in patients with Nexplanon.
- Conditions
- Birth Control, Contraception, Implant, Breakthrough Bleeding
- Trial name
- NCT04676061
- Testing
- Norethindrone acetate (NTA)
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Prolonged Pregnancy
Mechanical cervicAl ripeninG for Women With PrOlongedPregnancies
A pregnancy is considered ''prolonged'' from 41 weeks of gestation. Prolonged Pregnancies (PP) are associated with increased maternal morbidity: emergency caesarean, 3rd and 4th degree perineal lesions and postpartum haemorrhage.
- Trial name
- NCT02907060
- Testing
- Mechanical cervical ripening, Pharmacological cervical ripening
- Where
- 14 sites in France
- Volunteers
- 1,224 people
- Sponsor
- University Hospital, Tours