Clinical trials: Prolonged Sitting
Type 2 Diabetes Mellitus
The Effects of Reducing Prolonged Sitting Bouts in Individuals at High Risk of or With Type 2 Diabetes
Over 3 million in the United Kingdom are now diagnosed with type 2 diabetes, with current estimates suggesting this will rise to over 5 million by 2025.
- Trial name
- UP FOR 5 (NCT03482596)
- Testing
- Reducing/breaking prolonged sitting
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Sedentary Behavior, Hypertriglyceridemia
Interrupting Prolonged Sitting With Periodic Interval Exercise: Effect on Postprandial Lipemia
Investigating the effects of interrupting various lengths of prolonged sitting with bike sprints on post prandial lipemia the next day.
- Trial name
- NCT04241081
- Testing
- Interrupting Prolonged Sitting with Periodic Interval Exercise: Effect on Postprandial Lipemia
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Adult Office Workers
Point-of-Choice Prompts to Reduce Prolonged Sitting Time at Work
The purpose of this study is to determine whether an on-screen prompt put on the work computer every 30 minutes is effective in getting office workers to reduce prolonged periods of sitting at work.
- Trial name
- NCT01628861
- Testing
- MyRestBreak 1.0, education talk and leaflet
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Glasgow Caledonian University
Sedentary Behaviors, Breaking Prolonged Sitting With Physical Activity
Frequency of Interrupting Sitting and Cognitive Function
Rationale: Sedentary behavior (SB) has been associated with impaired cognitive function in elderly, and negatively impacts glucose metabolism.
- Trial name
- FISCF (NCT06700187)
- Testing
- Interrupting sitting with walking breaks
- Where
- Netherlands
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Hypertension
Effects of Coffee Versus Hibiscus Tea Consumption During Prolonged Sitting on Blood Pressure and Heart Rate
Modern lifestyles often involve long periods of sitting, which can increase the risk of heart problems, obesity, and other health issues. Diet also plays a key role in heart health.
- Trial name
- NCT07159152
- Testing
- Coffee, Hibiscus drink
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Saud University
Health Behavior
Effect of Breaking up Prolonged Sitting on Metabolic Flexibility
The investigators propose in this project to determine the effect of 3 days of frequent interruption of prolonged sitting on metabolic health in healthy overweight sedentary adults (n=24), as compared to 3 days including a single…
- Trial name
- NCT02258438
- Testing
- Uninterrupted sitting, Sitting + 1 bout of activity, Sitting + microbursts of activity
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Metabolic Syndrome X, Atherosclerosis
The Effects of Interrupting Prolonged Sitting With Intermittent Exercise on Postprandial Lipemia
The purpose of this study is to investigate the effect of interrupting prolong sedentary behavior with interval exercise on postprandial metabolism following a high fat glucose tolerance test.
- Conditions
- Metabolic Syndrome X, Atherosclerosis, Insulin Resistance, Hyperinsulinism
- Trial name
- NCT03856606
- Testing
- Prolonged sitting without exercise, Prolonged sitting with interval exercise
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Sedentary Lifestyle, Worksite
Mid-term Effect of a Novel Sit-to-stand Workplace (ACTIVE OFFICE) on Cognitive and Physiological Parameters
Prolonged sitting is a risk factor for cardiovascular and musculoskeletal diseases, diabetes, several types of cancer and all-cause mortality.
- Trial name
- NCT02825303
- Testing
- Workplace consisting of two height-adjustable desks
- Where
- Austria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences Upper Austria
Sedentary Employees
Better Breaks: Strength Breaks vs Walk Breaks for Sedentary Behavior Breaks
This study investigates the benefits of two different types of 2 minute activity breaks during sedentary workdays for people who sit for long periods of time in sedentary jobs.
- Trial name
- NCT06909097
- Testing
- Sitting breaks
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University
Healthy Participants
Association Between Central Sensitization and the Root Mean Square of Successive Differences
The aim of this study was to examine the relationship between central sensitization and resting RMSSD (Root Mean Square of Successive Differences) in individuals exhibiting prolonged sitting behavior, controlling for potential…
- Trial name
- NCT07755332
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Demiroglu Bilim University
Sedentary Lifestyle
Prompting Activity in a Workplace Setting
This dual-arm randomised study aims to test a multi-component intervention to reduce sedentary behaviour in a cohort of desk-based office workers.
- Trial name
- PAWS (NCT02785640)
- Testing
- Hourly prompts to stand delivered by Microsoft Outlook
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Glasgow Caledonian University
Hypoxemia
Pre-oxygenation in Sitting Position and Oxygen Reserve Index
This prospective, controlled and randomized study aims at comparing the effect of position on the oxygen reserve index alarm time which is considered as predictor of hypoxemia in prolonged apnea which might be faced during…
- Trial name
- NCT05964309
- Testing
- supine group, sitting group
- Where
- Saudi Arabia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Cardiovascular Risk Factor, Endothelial Dysfunction
Interrupting Sitting With High Intensity Exercise on Vascular Function in Adolescents Before and After a Mixed Meal
This study aims to investigate the effect of interrupting a three hour bout of prolonged sitting with high intensity interval exercise on lower limb blood vessel function in adolescents before and after a mixed meal challenge.
- Trial name
- NCT04337385
- Testing
- Interrupting 3 hours of prolonged sitting with high intensity interval exercise, 3 hours of prolonged sitting
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Sedentary Lifestyle
Sedentary Behavior Interrupted - A Pilot Study of Acute Interventions on Prolonged Sitting
Sedentary behavior, characterized by excess sitting time during waking hours, is detrimental to health and increases cardiometabolic disease risk, independent of moderate-to-vigorous physical activity.
- Trial name
- NCT02743286
- Testing
- Frequent sit-to-stands, Walking breaks, Stand more
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Sedentary Lifestyle, Overweight and Obesity
The Effect of Frequency and Duration of Breaks in Sitting Time on Metabolic Cardiovascular Risk Factors
The primary aim of this study is to investigate the acute effect of the frequency and duration of breaks in sitting time on the metabolic risk factor profile.
- Conditions
- Sedentary Lifestyle, Overweight and Obesity, Metabolic Disease
- Trial name
- BPS2 (NCT02951624)
- Testing
- Control, Breaker, Prolonger
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obesity
The Effects of Interrupting Prolonged Sitting With Bouts of Physical Activity on Neurocognitive Function in Obesity
It is projected that by 2030 almost 50% of adults in the USA will have obesity. High sedentariness and physical inactivity contribute to the obesity pandemic. Neurocognitive deficits compound the global burden of obesity.
- Trial name
- SITLess (NCT04926207)
- Testing
- Physical Activity Breaks Intervention, Talking Breaks Control
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Atherosclerosis, Metabolic Syndrome
Prolonged Sitting on Responses to Short-Term Exercise Training
Prolonged sitting has been shown to effect the response to a high fat tolerance test (HFTT) after acute exercise. This study will evaluate the effect of prolonged sitting on response to a HFTT after a short term training period.
- Trial name
- NCT03352063
- Testing
- Prolonged sitting with exercise, Active walking with exercise.
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Healthy Adults
Practical Approaches for Interrupting Prolonged Sitting to Improve Postprandial Glucose and Protein Metabolism
The present study will determine the impact of interrupting prolonged sitting with short, 2-minute walks or body-weight squats on: i) postprandial glycemia and insulinemia, and; ii) postprandial utilization of dietary amino…
- Trial name
- NCT03896828
- Testing
- Mixed-macronutrient meal
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cardiovascular Risk Factor, Type2 Diabetes
Breaking up Sitting With a Treadmill Desk in Office Workers
Sitting for long uninterrupted periods of time can increase risk of heart disease, diabetes and early death, even if you take part in the United Kingdom government guidelines for physical activity of 21/2 hours per week of…
- Conditions
- Cardiovascular Risk Factor, Type2 Diabetes, Sedentary Lifestyle
- Trial name
- NCT03468894
- Testing
- Treadmill desk walking
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Bedfordshire
Healthy, Ageing
Can Cocoa Flavanols Protect Endothelial Function During Prolonged Sitting in Healthy Older Adults?
Sitting time is high in older adults and has been shown to temporarily impair endothelial function and blood pressure. Flavanols, plant-derived compounds, acutely enhance endothelial function and reduce Blood pressure in older…
- Trial name
- NCT07265869
- Testing
- High-flavanol cocoa powder, Low-flavanol cocoa powder
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Birmingham