Clinical trials: Prolotherapy
TMJ Pain
Arthrocentesis Followed by Prolotherapy
we will do tmj joint lavage and followed by dextrose injection
- Trial name
- NCT04212975
- Testing
- joint lavage with dextrose
- Volunteers
- 60 people
- Sponsor
- Cairo University
Knee Osteoarthritis
Effect of Prolotherapy in Knee Osteoarthritis.
Patients with primary knee osteoarthritis will be included in the study, plain X-ray for the affected knee, followed by musculoskeletal ultrasound assessment will be done.
- Trial name
- NCT04178304
- Testing
- Prolotherapy with 25% Dextrose
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- University of Alexandria
Chronic Plantar Fasciitis, Chronic Heel Pain
Pulsed Radiofrequency Versus 5% Dextrose Injection in Chronic Plantar Fasciitis
This prospective, two-center, randomized controlled clinical trial aims to compare the effectiveness of ultrasound-guided pulsed radiofrequency and 5% dextrose injection in patients with chronic plantar fasciitis.
- Conditions
- Chronic Plantar Fasciitis, Chronic Heel Pain, Foot Pain
- Trial name
- NCT07688876
- Testing
- Ultrasound-Guided Pulsed Radiofrequency Treatment, Ultrasound-Guided 5% Dextrose Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara City Hospital Bilkent
Plantar Fascitis
Comparison of the Effectiveness of Local Ozone Injection and Dextrose Prolotherapy Injection in Chronic Plantar Fasciitis
The aim of our study was to investigate the effect of local ozone injection and dextrose prolotherapy applications on pain and foot functions to compare the efficacy and to evaluate the thickness of the plantar fascia.
- Trial name
- NCT05984121
- Testing
- Local ozon injections, Local dextroz prolotherapy injections, Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Temporomandibular Joint Disorders
Evaluation of the Effect of Dextrose Prolotherapy Versus Dry Needling Therapy
The hypertonic dextrose injection; Prolotherapy is a proliferation injection therapy that aims to trigger a low-grade inflammatory response inside the (TMJ), with the resultant captivation of abundant fibroblasts that regenerate…
- Trial name
- NCT05821985
- Testing
- The study group, The Control group
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Rotator Cuff Disease
Effects of Dextrose Prolotherapy in Rotator Cuff Disease
The aim of this prospective, randomized, controlled trial was to evaluate the clinical and ultrasonographic effects of dextrose prolotherapy on pain, shoulder function, range of motion, and ultrasonographic findings in patients…
- Trial name
- NCT04805242
- Testing
- Dextrose prolotherapy injection, Lidocaine-saline injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Dysmenorrhea, Prolotherapy
Posterior Tibia Nerve Neuroprolotherapy for Dysmenorrhea
The goal of this crossover study is to assessed the treatment efficacy of posterior tibia nerve neuroprolotherapy on dysmenorrhea. The primary outcome is the improvement of Visual Analogue Scale.
- Trial name
- NCT06294743
- Testing
- Posterior tibial nerve neuroprolotherapy, Acetaminophen 500Mg Tab
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taichung Armed Forces General Hospital
Whiplash Injury
Whiplash-associated Disorders - Needling Treatments Pilot Study
This pilot study is being conducted to provide proof of concept for three recently developed needling treatments, in the treatment of whiplash associated disorder type 2 (WAD-II).
- Trial name
- NCT01824810
- Testing
- Intramuscular Stimulation, myoActivation, Neural Prolotherapy
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia
Coccydynia
Ultrasound-Guided Dextrose Prolotherapy for Coccydynia: A Prospective Study
Coccydynia is a musculoskeletal condition characterized by pain in the coccygeal region, particularly exacerbated by sitting, and is associated with impaired quality of life and functional limitation.
- Trial name
- NCT07564167
- Testing
- Dextrose prolotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Pressure Ulcer
The Effect of Prolotherapy in the Care Process of Pressure Injuries
The goal of this [type of study: randomized controlled clinical trial] is to [Determining the effect of prolotherapy use on the wound care process].
- Trial name
- NCT05874284
- Testing
- Gelofusin
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Fenerbahce University
Temporomandibular Disorders (TMD), Temporomandibular Pain
Is the Combine Prolotherapy More Effective Than the Traditional Prolotherapy in Patients With Temporomandibular Joint Hypermobility?
1. Diagnosis and Indication You have been diagnosed with temporomandibular joint (TMJ) hypermobility and/or dysfunction, characterized by symptoms such as jaw clicking, locking, pain in the joint area, or difficulty in opening…
- Conditions
- Temporomandibular Disorders (TMD), Temporomandibular Pain, Hypermobility Syndrome (Disorder), Hypermobility, Joint
- Trial name
- NCT07020455
- Testing
- prolotherapy solution of 20% dextrose, Arthrocentesis with ringer solution
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Karadeniz Technical University
Temporomandibular Joint Disorders, Temporomandibular Disorder
Role of Liquid Phase Concentrated Growth Factors vs. Hypertonic Dextrose Prolotherapy for Management of Patients With Disc Displacement Without Reduction
Purpose of the study is to compare clinically, radiographically and biochemically the effect of intra- articular injection of hypertonic dextrose with a stabilization appliance and the intra- articular injection of 2 ml of liquid…
- Trial name
- NCT04557878
- Testing
- Hypertonic Dextrose Solution, Liquid Phase Concentrated Growth Factor (LPCGFs)
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Nourhan M.Aly
Partial Rotator Cuff Tears, Rotator Cuff Tendinopathy
Intralesional Versus Perilesional 5% Dextrose Injection in Partial Rotator Cuff Tears
This prospective, randomized, double-blind controlled clinical trial aims to compare the clinical and ultrasonographic outcomes of intralesional and perilesional 5% dextrose injection in patients with partial rotator cuff tears.
- Conditions
- Partial Rotator Cuff Tears, Rotator Cuff Tendinopathy, Shoulder Pain Chronic, Supraspinatus Tendon Tear
- Trial name
- NCT07688902
- Testing
- Intralesional 5% Dextrose Injection, Perilesional 5% Dextrose Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara City Hospital Bilkent
Chronic Shoulder Pain
Effects of Hypertonic Dextrose Water Injection for Supraspinatus Tendinosis Patients
Using hypertonic dextrose water for chronic supraspinatus tendinosis and using ultrasound as assessment tool to evaluate the effect of intervention.
- Trial name
- NCT03000205
- Testing
- hypertonic dextrose water, Normal saline and Lidocaine.
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Chronic Rotator Cuff Tendinopathy
Efficacy of Dextrose Prolotherapy Compare With ESWT in the Treatment of Chronic Rotator Cuff Tendinopathy
To compare the efficacy of dextrose solution injection with ESWT for pain reduction in rotator cuff tendinopathy. Additionally, secondary objective is to evaluate DASH and active range of motion of shoulder joint
- Trial name
- NCT06700746
- Testing
- Prolotherapy, Extracorporeal shock wave therapy (ESWT)
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Lateral Epicondylitis (Tennis Elbow), Lateral Epicondylitis
Comparison of ESWT and Single-Session 5% Dextrose Prolotherapy in Lateral Epicondylitis
Lateral epicondylitis is a common musculoskeletal disorder associated with pain and impaired upper extremity function. The aim of this study was to compare the effectiveness of extracorporeal shock wave therapy (ESWT) and…
- Trial name
- NCT07620678
- Testing
- Conventional Treatment group, Extracorporeal Shock Wave Therapy (ESWT), Dextrose prolotherapy (DPT)
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Cervical Radiculopathy
The Effect of Dry Needling and Prolotherapy on Pain, Function, and Quality of Life in Patients With Cervical Radiculopathy.
Cervical radiculopathy is characterized by neurological dysfunction caused by compression and inflammation of the spinal nerves or nerve roots of the cervical spine.
- Trial name
- NCT06457529
- Testing
- conventional treatment with Prolotherapy, Dry Needling and conventional treatment
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Superior University
Thumb Carpometacarpal Joint Osteoarthritis
Prolotherapy Versus Steroids for Thumb Carpo-metacarpal Joint Arthritis
Arthritis of the base of the thumb is a common debilitating problem. It is believed that laxity (loosening) of the joint leads to worsening arthritis in this joint.
- Trial name
- NCT00685880
- Testing
- Prolotherapy (10% dextrose solution), Betamethasone
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Chronic Shoulder Pain
Effects of Ultrasound-guide Hypertonic Dextrose Injection for Chronic Subacromial Bursitis
The aim of this study is to investigate the echoguide hypertonic injection and compared steroid injection in subacromial bursitis patients about clinical and ultrasound image presentation.
- Trial name
- NCT04916353
- Testing
- hypertonic dextrose water, Triamcinolone Acetonide.
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Knee Osteoarthritis, Dextrose Prolotherapy Injection
The Effect of Dextrose Prolotherapy on Isokinetic Power in the Treatment of Knee Osteoarthritis
Osteoarthritis is a degenerative joint disease characterized by erosion of the articular cartilage, bone hypertrophy at the margins of the joint, subchondral sclerosis, and some biochemical and morphological changes in the…
- Conditions
- Knee Osteoarthritis, Dextrose Prolotherapy Injection, Physical Therapy
- Trial name
- NCT04958213
- Testing
- Dextrose prolotherapy injection, conventional physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mustafa Kemal University