Clinical trials: Prone Positioning
COVID-19, Proning
Non-ventilated Prone Positioning in the COVID-19 Population
In the COVID-19 healthcare crisis, one possible treatment therapy that has generated the most discussion is that of proning, or the position in which the patient lays face down as opposed to face up for a period of time.
- Conditions
- COVID-19, Proning, Oxygenation, Length of Stay
- Trial name
- NCT05957588
- Testing
- Proning group, Control group
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Baylor St. Luke's Medical Center
Skin-to-skin, Preterm Birth
Comparison of Two Different Skin-to-skin Contact Techniques: Sustained Diagonal Flexion vs. Traditional
This is a prospective, controlled randomized study designed to compare the effects of two methods of skin-to-skin positioning of preterm infants: the prone positioning method currently used (according to the World Health…
- Trial name
- NCT06154148
- Testing
- Sustained Diagonal Flexion positioning, Traditional prone position
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Investigative Techniques
Study on the Effectiveness and Feasibility of Prone Position Ventilation Technology in Congenital Heart Disease
The purpose of this study was to compare the effects of conventional lying position and prone position ventilation on infants with acute lung injury after surgery for congenital heart disease.
- Trial name
- NCT04607993
- Testing
- Prone position ventilation technique
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Infant Motor Development
Determining Optimal Dosage of Prone Positioning in Early Infancy
The proposed study is a longitudinal, randomized control trial designed to determine the dosage of daily 'tummy time' needed in early infancy to influence ideal motor development and healthy body composition.
- Trial name
- Tummytime (NCT03134859)
- Testing
- Tummy Time
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Newborn Infant, Newborn Health
The Effect of Different Positions Given to the Newborn During Delayed Cord Clamping on Physiological Indicators and Comfort
During intrauterine life, the fetus is connected to the mother via the placenta; with birth, the extrauterine adaptation process begins.
- Conditions
- Newborn Infant, Newborn Health, Delayed Cord Clamping
- Trial name
- Cord Clamping (NCT07719751)
- Testing
- Prone position, Left side lying position
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mersin University
Infratentorial Neoplasms
Effects of the Prone and the Sitting Positions on the Brain Oxygenation in Posterior Fossa Surgery
The sitting or prone positions are used for posterior fossa surgery. Although the sitting position may cause hemodynamic instability, venous air embolism, it also provides optimum access to midline lesions, decreases intracranial…
- Trial name
- NCT02933749
- Testing
- SctO2, BIS
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Postoperative Atelectasis
Supine vs Prone Position and Atelectasis Assessed by Lung Ultrasound
Atelectasis frequently develops during and after general anesthesia due to factors such as anesthesia-induced diaphragmatic dysfunction, reduced functional residual capacity, altered ventilation-perfusion matching, and surgical…
- Trial name
- LUS-ATELEC (NCT07320092)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pressure Ulcer
Pressures During Prone Positions in Healthy Volunteers
Prone positioning (PP) reduces mortality in the most severe cases of acute respiratory distress syndrome (ARDS). Despite the benefits of PP, this technique presents adverse effects such as an increased risk of bedsores, linked to…
- Trial name
- HEALTHY-PRONE (NCT06025370)
- Testing
- Prone Position
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Obesity
Colonoscopy in the Prone Position for Patients With BMI Greater Than 30
In the United States, colonoscopy has become the most commonly used screening test for colorectal cancer. Colonoscopy is typically performed with the patient starting in the left lateral decubitus position, however there is…
- Trial name
- NCT03337217
- Testing
- Position during colonoscopy
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Anesthesia, Anorectal Surgery
Spinal Anesthesia Versus General Anesthesia Using Laryngeal Mask Airway for Anorectal Surgeries in Prone Position
Anorectal surgeries are of the commonest elective surgeries that are performed worldwide under different types of anaesthesia. The aim of this prospective interventional study was to compare the use of general anaesthesia (GA)…
- Trial name
- NCT04214977
- Testing
- Spinal Anesthesia for Anorectal Surgeries in Prone Position, General Anesthesia Using Laryngeal Mask Airway for Anorectal Surgeries in Prone Position
- Where
- Jordan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Newborn; Anemia, Umbilical Cord Problem
Supine vs Prone Position During Delayed Cord Clamping
This study is conducted to evaluate if the prone position of the newborn on the chest of his mother at birth before delayed cord clamping leads to better hematocrit and hemoglobin at 24-48 hours of life compared to supine…
- Trial name
- DCC (NCT03697967)
- Testing
- supine or prone position
- Where
- Canada
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital
Airway Edema, Obstructive Sleep Apnea
Comparison of the Effect of Supine and Prone Position on the Ultrasonographic Airway Measurements
The aim of this study is to compare the preoperative and postoperative ultrasonographic measurements of patients undergoing in the prone position and the change in upper airway edema.
- Conditions
- Airway Edema, Obstructive Sleep Apnea, Respiratory Complication
- Trial name
- NCT05197400
- Testing
- preoperative airway ultrasonography, postoperative airway ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Breast Cancer, Radiation Dermatitis
Topical Betamethasone Versus Moisturizer in Preventing Radiation Dermatitis in Large-Breasted Patients Treated in the Prone Position
Radiotherapy (RT) is common in the treatment of breast cancer, however, 95% of breast cancer patients are at risk of developing acute and chronic skin toxicities known as radiation dermatitis (RD) which includes symptoms such as…
- Trial name
- NCT06915857
- Testing
- Topical Betamethasone
- Where
- Canada
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Venous Hemodynamics
Effects of Positive End-Expiratory Pressure (PEEP) and Prone Positioning in Healthy Volunteers on Venous Hemodynamics Including the Venous Excess Ultrasound (VExUS) Score
The hemodynamic effects of proning and PEEP may vary depending on pre- existing cardiac function, lung mechanics, and volume status, and the available evidence remains conflicting.
- Trial name
- VeNIVPro (NCT07273617)
- Testing
- application of PEEP: starting PEEP = 15 mbar, application of PEEP: starting PEEP = 0 mbar
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Mechanical Ventilation
The Effect of Intraoperative Ventilation Mode on Hemodynamics and Lung Dynamics
In this study, it was aimed to compare the effects of pressure-controlled volume-guaranteed ventilation (PCV-VG) and volume-controlled ventilation (VCV) on lung dynamics and hemodynamics in patients undergoing vertebral surgery…
- Trial name
- NCT05776589
- Testing
- The mechanical ventilation mode
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Izmir Ataturk Training and Research Hospital
COVID, ARDS
Awake Prone Positioning and Oxygen Therapy in Patients With COVID-19
The prone position strategy for patients with acute respiratory distress syndrome (ARDS) is simple and cost-effective from the first description on its use in patients with acute respiratory failure to improve hypoxemia.
- Conditions
- COVID, ARDS, Pneumonia
- Trial name
- APRONOX (NCT04407468)
- Testing
- Prone position
- Where
- 6 sites in Mexico
- Volunteers
- 827 people, healthy volunteers welcome
- Sponsor
- Hospital General San Juan del Rio
Prone Position, Pressure Ulcer
Evaluation of the Impact of the PRONEtect Education Hub vs. Classic Lecture, on the Competencies of Nursing Students
The goal of this randomised controlled trial is to compare the impact of online educational material versus a classic lecture on the confidence levels, knowledge and knowledge application of final-year nursing students.
- Trial name
- NCT05575869
- Testing
- (online) PRONEtect educational material, Classic (normal) one hour lesson/lecture
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Ghent
Healthy
Anti-FLEX: Flexed Levering of Gluteal Vessels
The purpose of this study is to evaluate the effect of the gluteal vasculature in the prone and jackknife positions.
- Trial name
- NCT03286231
- Testing
- CT imaging
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Blindness
Determine the Effect of Intraocular Pressure (IOP), Optic Nerve Imaging, Venous Congestion in Volunteers Prone Position 5 Hours
The purpose of this study is to provide data that would give the investigators a better understanding of the physiologic changes that occur and may contribute to post operative blindness.
- Trial name
- NCT00875043
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Prone Position, Cardiac Output
Effect of Prone Position on Liver Blood Flow and Function
Recent occurrence of significant post-operative liver impairment at Nottingham University Hospitals NHS Trust has prompted investigation into whether interaction between general anaesthesia and prone positioning (lying face down)…
- Conditions
- Prone Position, Cardiac Output, Liver Circulation
- Trial name
- PLiF (NCT01781260)
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Nottingham