Clinical trials: Prone Positioning
ARDS, Prone Position
Determine the Effect of Prone Positioning in Adults With ARDS by Electrical Impedance Tomography
determine the effect of prone positioning on ventilation and perfusion distribution in adults with acute respiratory distress syndrome by electrical impedance tomography
- Conditions
- ARDS, Prone Position, Electrical Impedance Tomography
- Trial name
- NCT04725227
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Zhongshan Hospital
Acute Respiratory Failure
A Prospective Observational Cohort Study of Awake Prone Position Ventilation Strategy in Patients With Acute Respiratory Failure
Awake prone positioning has been used widely for patients with COVID-19.Many research results are not uniform on the key issue of whether the prognosis of patients can be improved，and most of the subjects were patients with…
- Trial name
- NCT05570903
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Kidney Stone
Effects of Abdominal Cushion on PCNL in Prone Position
Percutaneous nephrolithotomy (PCNL) is the first choice for the treatment of ≥ 2cm renal stones. The positions of PCNL includes supine, prone and lateral. PCNL has been performed in my center for nearly twenty years.
- Trial name
- NCT03797027
- Testing
- Percutaneous Nephrolithotomy without an abdominal cushion, Percutaneous Nephrolithotomy with an 5 cm abdominal cushion
- Where
- China
- Volunteers
- 180 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Acute Chest Syndrome, Sickle Cell Anemia
Awake Prone Positioning for Severe Acute Chest Syndrome
Acute chest syndrome (ACS) is the leading cause of admission to intensive care and the leading cause of death in patients with sickle cell disease.
- Trial name
- PRONE-ACS (NCT06698120)
- Testing
- Awake prone positioning (APP)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prone Positioning, Bronchopulmonary Dysplasia
Prone Versus Supine Positioning and the Impact on Bronchopulmonary Dysplasia in Very Low Birth Weight Infants.
In this pilot study, the investigator team aims to evaluate whether standardized prone positioning compared to usual positioning improves moderate to severe bronchopulmonary dysplasia (BPD) rates as assessed at 36 weeks post…
- Trial name
- NCT04890158
- Testing
- Prone positioning for a total of 6 hours daily
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Montefiore Medical Center
Thoracic Surgical Procedures, One-lung Ventilation (OLV)
Study of Cardiac Power Index During Supine, Lateral, and Between Left and Right Positions During Two- and One-Lung Ventilation (OLV): Comparison of Hemodynamic Changes After Lung Recruitment Maneuver and Fluid Challenge Among Responders and Non-Responders (SVI, MAP, CPI Changes).
The aim of this trial is to study the changes of the Cardiac Power Index (CPI) during supine and lateral decubitus position in two and one lung ventilation respectively.
- Conditions
- Thoracic Surgical Procedures, One-lung Ventilation (OLV), Hemodynamic Changes
- Trial name
- NCT07037225
- Testing
- Fluid challenge during one-lung ventilation (OLV) in the lateral decubitus position, Hemodynamic monitoring
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Maria Fountoulaki
Acute Respiratory Distress Syndrome
Extended Prone Positioning for Intubated ARDS
Acute respiratory distress syndrome (ARDS) is an acutely induced respiratory failure characterised by the appearance of bilateral alveolar opacities on imaging and hypoxemia(1).
- Trial name
- PROSECO (NCT07126964)
- Testing
- 40-hour prone session (intervention), 16-hour prone session (control)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prone Position, Cardiac Output
Effect of Prone Position on Liver Blood Flow and Function
Recent occurrence of significant post-operative liver impairment at Nottingham University Hospitals NHS Trust has prompted investigation into whether interaction between general anaesthesia and prone positioning (lying face down)…
- Conditions
- Prone Position, Cardiac Output, Liver Circulation
- Trial name
- PLiF (NCT01781260)
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Covid19, Pneumonia, Viral
Prone Position and Respiratory Outcomes in Non-Intubated COVID-19 PatiEnts The "PRONE" Study
The overall objective of this study is to determine whether a positional maneuver (e.g., prone positioning) decreases the need for escalation of respiratory-related care in patients with coronavirus (COVID-19) pneumonia.
- Trial name
- PRONE (NCT04517123)
- Testing
- Prone Positioning
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- Johns Hopkins University
Osteotomies
Comparison of Supine to Prone Position During Major Spinal Surgery
During mechanical ventilation, the alveolar recruitment maneuver (ARM) is to apply a positive end-expiratory pressure (PEEP) (generally 30 cm H2O) for a period of at least 30 seconds.
- Trial name
- MRA-RACHIS (NCT02285946)
- Testing
- major spine surgery
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
CHD, Heart Defects, Congenital
The Effects of Different Prone Positioning Angles on Cardiopulmonary Function in Children After Congenital Heart Disease Surgery: A Randomized Controlled Trial
The goal of this randomized controlled trial is to learn if different head-elevated prone positioning angles can optimize cardiopulmonary function and enteral nutrition tolerance in infants and children after congenital heart…
- Conditions
- CHD, Heart Defects, Congenital, Hypoxia, Respiratory Insufficiency
- Trial name
- PACE-CHD (NCT07323979)
- Testing
- 10° Head-Elevated Prone Positioning, 30° Head-Elevated Prone Positioning, 45° Head-Elevated Prone Positioning
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Guangdong Provincial People's Hospital
Acute Respiratory Distress Syndrome
Fluid Responsiveness Prediction During Prone Position
Predicting fluid responsiveness is primordial when caring for patients with circulatory shock as it allows correction of preload-dependent low cardiac output states, while preserving patients of the deleterious effects of…
- Trial name
- PROLOAD (NCT05898269)
- Testing
- Trendelenburg maneuver, End-expiratory occlusion test (EE OCC), End-expiratory and end-inspiratory occlusion test (EI OCC)
- Where
- 4 sites in France
- Volunteers
- 96 people
- Sponsor
- Hospices Civils de Lyon
Epilepsy, Pulmonary Embolism
iMRI Prone Positioning Frame Design Feasibility Study
The goal of this study is to learn if the prototype adjustable prone positioning frame is a feasible design for use during neurosurgical procedures which utilize intraoperative magnetic resonance imaging (iMRI).
- Trial name
- NCT06388512
- Testing
- prototype prone positioning device
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Kansas Medical Center
Bone Marrow Examination, Urologic Surgical Procedures
Comparison of the Clinical Performance and Safety of the Ambu®AuraGainTM Laryngeal Mask in Children Undergoing Surgery in the Supine and Prone Position - A Prospective, Noninferiority Clinical Trial
The Ambu Auragain is a 2nd generation laryngeal mask airway that is widely used in adult and pedicatric patients. While its use is generally recommended in patients undergoing surgery in the supine position, depending on patient…
- Conditions
- Bone Marrow Examination, Urologic Surgical Procedures, Orthopedic Surgery
- Trial name
- NCT05286021
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Yonsei University
COVID-19 Acute Respiratory Distress Syndrome
Prone Positioning and R/I Ratio in COVID-19 Patients With ARDS (SyDRAC-DV)
The purpose of this study is to determine the efects of prone positioning on the recruitment- to-inflation ratio in COVID-19 patients with acute respiratory distress syndrome.
- Trial name
- SyDRAC-DV (NCT05360862)
- Testing
- Prone positioning session
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Anaesthesia
Measuring the Effect of External Pressure on the Regional Cerebral Oxygen Saturation Monitored by Near-infrared Spectroscopy(NIRS) Technology
During general anaesthesia, to ensure sufficient oxygen supply to the brain, the NIRS technology can be used. It consist of two sensors placed on the forehead, and measures the oxygen saturation of the tissue underneath the…
- Trial name
- NCT01971996
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Coronavirus Infection, Oxygen Deficiency
Prone Positioning in Spontaneously Breathing Nonintubated Covid-19 Patient: a Pilot Study
The prone position consists of placing the patient on his or her stomach with the head on the side, during sessions lasting several hours a day and could help spontaneous ventilate the patient.
- Trial name
- ProCov (NCT04344106)
- Testing
- Prone positioning
- Where
- France
- Volunteers
- 25 people
- Sponsor
- ELHARRAR Xavier
Prone Position, Pressure Ulcer
Efficacy of HOFA Versus Hydrocolloid Dressings in the Prevention of PUs in Critically Ill Prone Patients
Introduction: Prone position (PP) treatment as a rescue strategy for patients with acute respiratory distress syndrome (ARDS) is a technique increasingly used in our daily practice and, as a result of the current health situation…
- Trial name
- NCT05198167
- Testing
- Hyperoxygenated fatty acids, Hydrocolloid dressings
- Where
- Spain
- Volunteers
- 262 people
- Sponsor
- Puerta de Hierro University Hospital
Community-acquired Pneumonia
Awake Prone Positioning of Patients Suffering Community Acquired Pneumonia Requiring Nasal High Flow Therapy
Community acquired pneumonia, in particular when requiring oxygen therapy because of acute hypoxemic respiratory failure and meeting acute respiratory distress syndrome (ARDS) criteria frequently leads to tracheal intubation and…
- Trial name
- PRONECAP (NCT06966310)
- Testing
- Prone position
- Where
- 38 sites in France
- Volunteers
- 1,078 people
- Sponsor
- University Hospital, Tours
Cerebral Lesion
Internal Carotid Artery Blood Flow in Infants With Prone Position
Little is known about how implementation of prone position contributes to general anesthesia-induced decrease in cerebral blood flow in infants.
- Trial name
- NCT05391282
- Testing
- ultrasound assessment
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital