Clinical trials: Prone Positioning
Ards
Duration of Prone Position in the Severe Acute Respiratory Syndrome Coronavirus 2 (COVID-19).
The OMELETTE study is a randomised, controlled, unicentric, open-label study to prove the noninferiority of reduced prone position (PP) sessions (more tan 16 hours) versus prolonged PP (48 hours).
- Trial name
- OmeLEtte (NCT05012267)
- Testing
- 16-hour PP
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Ignacio Saez de la Fuente
Community-acquired Pneumonia
Awake Prone Positioning of Patients Suffering Community Acquired Pneumonia Requiring Nasal High Flow Therapy
Community acquired pneumonia, in particular when requiring oxygen therapy because of acute hypoxemic respiratory failure and meeting acute respiratory distress syndrome (ARDS) criteria frequently leads to tracheal intubation and…
- Trial name
- PRONECAP (NCT06966310)
- Testing
- Prone position
- Where
- 38 sites in France
- Volunteers
- 1,078 people
- Sponsor
- University Hospital, Tours
Hypoxia
The Effect of Prolonged Inspiratory Time on Pulmonary Mechanics in Obese Patients
The area of aesthesia-induced atelectasis is much larger in the obese compared with the non-obese, but there may also be more airway closure and impaired matching of ventilation and lung blood flow.
- Trial name
- NCT02961920
- Testing
- IE ratio 1:1, IE ratio 1:2
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Gachon University Gil Medical Center
Acute Respiratory Distress Syndrome (ARDS)
Prevalence of Prone Positioning Use in ARDS Patients
Prone positioning has been shown to improve survival in patients with acute respiratory distress syndrome (ARDS). However, a recent large observational study found that prone positioning was used in only 7% of all ARDS patients…
- Trial name
- APRONET (NCT02842788)
- Testing
- Prone positioning
- Where
- France
- Volunteers
- 736 people
- Sponsor
- Hospices Civils de Lyon
Lumbar Disc Herniation, Spinal Surgery
Comparison of 5 vs 8 cmH₂O PEEP on Respiratory Mechanics in Prone Lumbar Surgery
This randomized controlled clinical trial aims to compare the effects of two different positive end-expiratory pressure (PEEP) levels (5 cmH₂O and 8 cmH₂O) on respiratory mechanics in patients undergoing lumbar spine surgery in…
- Conditions
- Lumbar Disc Herniation, Spinal Surgery, Prone Position, General Anesthesia
- Trial name
- PROPEEP (NCT07545733)
- Testing
- Mechanical Ventilation (PEEP)
- Volunteers
- 60 people
- Sponsor
- Harran University
Vision; Disorder, Loss
The Influence of Prone Position for Spinal Surgery on Visual Acuity
This study investigated the effect of desflurane and propofol anesthesia on visual acuity in patients in prone position for spinal surgery.
- Trial name
- NCT03644641
- Testing
- Desflurane Group, Propofol Group
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Hradec Kralove
Anaesthesia
Measuring the Effect of External Pressure on the Regional Cerebral Oxygen Saturation Monitored by Near-infrared Spectroscopy(NIRS) Technology
During general anaesthesia, to ensure sufficient oxygen supply to the brain, the NIRS technology can be used. It consist of two sensors placed on the forehead, and measures the oxygen saturation of the tissue underneath the…
- Trial name
- NCT01971996
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Renal Stones
Prone Flexed Position in Percutanous Nephrolithotomy
prone flexed position in percutanous nephrolithotomy in comparsion with standard prone position. A randomized controlled trial.
- Trial name
- NCT04345835
- Testing
- Percutanous nephrolithotomy (PCNL)
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Kafrelsheikh University
Lung Cancer
Prone Patient Positioning in Reducing Tumor Motion and Improving Breathing Reproduction in Patients With Lung Cancer Undergoing Radiation Therapy
This clinical trial studies prone patient positioning in reducing tumor motion and improving breathing reproduction in patients with lung cancer undergoing radiation therapy.
- Trial name
- NCT01851161
- Testing
- computed tomography, 4-dimensional computed tomography, radiation therapy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Virginia Commonwealth University
Severe Acute Respiratory Syndrome Coronavirus 2, Electric Impedance
Prone Positioning and Regional Ventilation in Mechanically Ventilated COVID-19 Patients
The consensus therapeutic strategy implies that COVID patients with acute lung injury due to coronavirus are routinely placed in prone position in an attempt to improve oxygenation by increasing ventilation homogeneity.
- Conditions
- Severe Acute Respiratory Syndrome Coronavirus 2, Electric Impedance, Prone Positioning
- Trial name
- COVID-19_EIT (NCT04359407)
- Testing
- Prone positioning
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- Walid HABRE
ARDS, Human, Catheter Infection
Prone Position Impact in ARDS Patients on the Incidence of Central Venous Catheter Colonization
Catheter colonization, catheter-associated infection and catheter-associated bacteremia are a major challenge for resuscitation unit.
- Trial name
- ILCDV (NCT03405038)
- Where
- France
- Volunteers
- 202 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Respiratory Failure, ICU
A Wake Prone Positioning in Non-intubated Patients With Acute Hypoxemic Respiratory Failure
Patients admitted to the ICU with severe hypoxemia are at high risk for mortality. Few therapies have been proven to improve patient outcomes or duration of mechanical ventilation e.g.
- Trial name
- NCT05698004
- Testing
- prone positioning
- Volunteers
- 244 people
- Sponsor
- Montaser Gamal Ahmed
Anaesthesia, Adverse Effects
Laryngeal Mask or Endotracheal Tube for Back Surgery in the Prone Position
The aim of the study is to compare anaesthesia (for back surgery) using endotracheal intubation (patients anaesthized in the supine position)with anaesthesia using a laryngeal mask (anaesthesia induced and the laryngeal mask…
- Trial name
- NCT01041352
- Testing
- laryngeal mask, endotracheal tube
- Where
- Denmark
- Volunteers
- 136 people
- Sponsor
- Glostrup University Hospital, Copenhagen
COVID-19, Proning
Non-ventilated Prone Positioning in the COVID-19 Population
In the COVID-19 healthcare crisis, one possible treatment therapy that has generated the most discussion is that of proning, or the position in which the patient lays face down as opposed to face up for a period of time.
- Conditions
- COVID-19, Proning, Oxygenation, Length of Stay
- Trial name
- NCT05957588
- Testing
- Proning group, Control group
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Baylor St. Luke's Medical Center
Laminectomy, Intraocular Pressure
Measurement of Intraocular Pressure in Patients Undergoing Laminectomy in the Prone Position
Laminectomy surgeries, typically performed for lumbar disc herniation and spinal disorders, are often lengthy surgical procedures requiring patients to be in the prone position.
- Conditions
- Laminectomy, Intraocular Pressure, Prone Position
- Trial name
- NCT07067008
- Volunteers
- 60 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Pressure Ulcer, Respiratory Distress Syndrome, Acute
Extended Prone Position Duration COVID-19-related ARDS: a Retrospective Study
Prone position (PP) is standard of care for mechanically ventilated patients with severe acute respiratory distress syndrome in the intensive care unit (ICU). Recommendations suggest PP durations of at least 16 hours.
- Conditions
- Pressure Ulcer, Respiratory Distress Syndrome, Acute, Hypoxemic Respiratory Failure, COVID-19 Acute Respiratory Distress Syndrome
- Trial name
- NCT05124197
- Testing
- prone position
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Hôpital Louis Mourier
Infant Motor Development
Determining Optimal Dosage of Prone Positioning in Early Infancy
The proposed study is a longitudinal, randomized control trial designed to determine the dosage of daily 'tummy time' needed in early infancy to influence ideal motor development and healthy body composition.
- Trial name
- Tummytime (NCT03134859)
- Testing
- Tummy Time
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Myelomeningocele, Prone Position
Cuff Pressure in Infants
The changes in the cuff pressure in the absence of nitrous oxide are less clear.In the current study, we aim to determine the changes in cuff pressure over time in infants undergoing myelomeningocele repair in prone position…
- Trial name
- NCT03088761
- Testing
- cuffed tracheal tube
- Volunteers
- 20 people
- Sponsor
- Istanbul Science University
Spinal Diseases, Local Anesthesia
The Effect of Dexmedetomidine Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia
Evaluate safety and efficacy of dexmedetomidine in minimally invasive spine surgery under local anesthesia sedation.Explore the appropriate concentration of dexmedetomidine, whether or not can reduce the amount of local…
- Trial name
- NCT02535273
- Testing
- Dexmedetomidine, Lidocaine, Low-dose Dexmedetomidine
- Volunteers
- 212 people
- Sponsor
- Tang-Du Hospital
Gastric Residual Volume, Abdominal Oxygenation
The Effect of Position Given to Preterms After Feeding on Gastric Residual Volume, Abdominal Oxygenation and Fractional Oxygen Extraction
This study is a PhD dissertation. In this study, the investigators aim to investigate the effects of three different positions after feeding on gastric residual volume, abdominal oxygenation using near infrared spectroscopy…
- Conditions
- Gastric Residual Volume, Abdominal Oxygenation, Fractional Oxygen Extraction, Positioning (Prone, Right Lateral and Semi-Elevated Supine Position)
- Trial name
- NCT05888090
- Testing
- Prone, right lateral, and semi-elevated supine positions, Semi-elevated supine, prone, and right lateral positions, Right lateral, semi-elevated supine, and prone positions
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Istanbul University - Cerrahpasa