Clinical trials: Propanolol
Postpartum Hemorrhage
In Vitro Optimization of Oxytocin-induced Myometrial Contractility by Propranolol
The rates of cesarean deliveries (CD) and postpartum hemorrhage (PPH) are on the rise, with failed induction and augmentation of labor as major contributing factors.
- Trial name
- NCT03434444
- Testing
- Oxytocin, Propranolol
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pulmonary Disease, Chronic Obstructive
A Study to Investigate the Pharmacology of a Dual Pharmacophore in Healthy Volunteers
Study will investigate the pharmacodynamics of a dual pharmacophore in which a combination of GSK961081 and Propanolol is used to give a total effect of bronchodilation.
- Trial name
- NCT00687700
- Testing
- GSK961081, Propranolol
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Labour;Obstructed, Labor Dystocia
Propranolol for Protracted Labor
Induction of labor is one of the most common procedures performed on labor and delivery. In the United States, more than 20 percent of pregnant women undergo an induction of labor [1].
- Trial name
- PRO-Labor (NCT04741698)
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Prostate Cancer
Perioperative Propranolol During Prostatectomy to Decrease Cancer Recurrence
The purpose of this study is to assess the feasibility of conducting a larger randomized controlled trial to assess the efficacy of perioperative propranolol capsules compared with placebo capsules in decreasing recurrence of…
- Trial name
- PeP-RALP (NCT05679193)
- Testing
- Propranolol
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Dysfunctional Labor
Trial of Oxytocin Alone Versus Oxytocin and Propranolol for the Treatment of Abnormal Labor
The purpose of this study is to determine whether propranolol is better than oxytocin for the treatment of labor abnormalities. The endpoint is the rate of vaginal delivery experienced by women receiving prolonged oxytocin versus…
- Trial name
- NCT00315913
- Testing
- Propranolol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Major Depressive Disorder
A Study of LY2216684 in Healthy Participants Receiving Albuterol or Propanolol
The purpose of this study is to determine the effect of LY2216684 on heart rate of participants receiving Albuterol and Propranolol. Information about any side effects that may occur will also be collected.
- Trial name
- NCT01263197
- Testing
- LY2216684, albuterol, propranolol
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Hypertension
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Propranolol/Carvedilol Versus Atenolol/Bisoprolol/Sotalol
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the…
- Trial name
- NCT05794997
- Testing
- Propranolol or Carvedilol, Atenolol, Bisoprolol or Sotalol
- Where
- United States
- Volunteers
- 817,337 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Poor; Labor
The Effect of Coadministration of Oral Propranolol to Oxytocin on Induction of Labor
The effect of coadministration of oral propranolol to oxytocin on induction of labor.
- Trial name
- NCT02702674
- Testing
- propranolol, Oxytocin
- Where
- Egypt
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Post-Traumatic Stress Disorder
Effect of Propranolol on Preventing Posttraumatic Stress Disorder
This study will assess the effectiveness of taking propranolol soon after a traumatizing incident in reducing the incidence and severity of posttraumatic stress disorder in acutely traumatized individuals.
- Trial name
- NCT00158262
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Stress Disorders, Post-Traumatic
Propranolol Reactivation Mismatch (PRM) Treatment for PTSD
The aim of the proposed work is to gather pilot data from an attempt to enhance the ability of propranolol reactivation (PR) to improve PTSD symptoms by incorporating into the design a mismatch (PRM) between what is expected and…
- Trial name
- NCT03652922
- Testing
- Reactivation Mismatch
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cavernous Malformations,Cerebral and/or Spinal
Oral Propanolol for Surgically Inaccessible Cavernous Malformations
The purpose of this study is to evaluate the role of propranolol as an alternative treatment for cavernous malformation in patients that may not be ideal candidates for surgery.
- Trial name
- NCT03523650
- Testing
- Propranolol Oral Tablet
- Where
- United States
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Primary Lymphedema
Propranolol Dose Escalation in Lymphedema in Patients
This is a study to investigate the safety and efficacy of propranolol in the treatment of patients with primary lymphedema. The primary goal is to assess patient tolerability of increasing doses of propranolol.
- Trial name
- NCT02595996
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Columbia University
TBI (Traumatic Brain Injury)
Propranolol for the Treatment of Traumatic Brain Injury
Traumatic brain injury (TBI) is a leading cause of global disease and directly affects over 1.5 million Canadians, with 165 000 TBIs occurring yearly in Canada.
- Trial name
- NCT06262061
- Testing
- Propranolol
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre
Memory, Heart Rate
Effects of Propranolol on the Encoding and Retrieval of Emotional Material After Single Dose Administration in Healthy Young Subjects
1. To evaluate the effects of a single oral (80 mg) dose of propranolol on the encoding of emotional pictures as assessed by peripheral physiological and electrocortical parameters in a healthy population. 2.
- Conditions
- Memory, Heart Rate, Skin Electric Conductance, Amylase
- Trial name
- NCT00889096
- Testing
- propranolol
- Where
- Germany
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Healthy
A Study of Ponesimod in Healthy Adult Participants Receiving Propranolol at Steady State
The primary purpose of this study is to evaluate the effect of the up-titration regimen of ponesimod on heart rate (HR) and other electrocardiogram (ECG) parameters when administrated to healthy adult participants receiving…
- Trial name
- NCT03882255
- Testing
- Ponesimod dose range (2 - 20 mg), Propranolol 80 mg
- Where
- Belgium
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Pregnancy, Prolonged
Propranolol Rescue of Prolonged Labor
A double-blind placebo controlled randomized trial comparing cesarean delivery rates in women given IV propranolol versus placebo for treatment of prolonged labor.
- Trial name
- PROPEL (NCT04299438)
- Testing
- Propranolol Hydrochloride, Saline
- Where
- 2 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Lisa Levine
To Determine Bioequivalence Under Fed Conditions
Bioavailability Study of Propranolol Under Fed Conditions
To compare the single-dose bioavailability of Propranolol 160 Mg ER Capsules with Inderal-La
- Trial name
- NCT00652600
- Testing
- Propranolol, Inderal-LA
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Par Pharmaceutical, Inc.
Healthy
Analysis of Atropine and Propranolol Induced Changes
The purpose of this study is to learn the effects of genetic make up on response to the drugs atropine and propranolol, to examine how changes in heart rate and blood pressure can be measured, and to test a new statistical…
- Trial name
- NCT00251602
- Testing
- Atropine, Propranolol, Normal Saline
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Alcohol Drinking
Does Propranolol, a Beta Blocker, Attenuate Stress-Induced Drinking?
For this protocol, the investigators plan to conduct a pilot study evaluating the effect of propranolol on alcohol consumption. Using a parallel design, the investigators plan to randomize 20 non-treatment seeking adults with…
- Trial name
- NCT03588754
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Dependence, PTSD
Neuromodulation of Trauma Memories in PTSD & Alcohol Dependence
The purpose of this study is to examine the effect of propranolol versus placebo on craving, distress and cue reactivity to trauma and alcohol cues.
- Trial name
- NCT01055171
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina