Clinical trials: Propanolol
Healthy
A Study of Lasmiditan and Propranolol in Healthy Participants
This study will assess the effects on heart rate and blood pressure when a single dose of lasmiditan is administered with a daily dose of propranolol.
- Trial name
- NCT03270644
- Testing
- Lasmiditan, Propranolol
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Multiple Myeloma
Study of Propranolol to Decrease Gene Expression of Stress-Mediated Beta-Adrenergic Pathways in HCT Recipients
This is a randomized controlled pilot study designed to evaluate whether the beta-adrenergic antagonist propranolol is effective in decreasing gene expression of stress-mediated beta-adrenergic pathways among a cohort of…
- Trial name
- NCT02420223
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical College of Wisconsin
Post-Traumatic Stress Disorder
Effect of Propranolol on Preventing Posttraumatic Stress Disorder
This study will assess the effectiveness of taking propranolol soon after a traumatizing incident in reducing the incidence and severity of posttraumatic stress disorder in acutely traumatized individuals.
- Trial name
- NCT00158262
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Temporomandibular Disorders
Study of Orofacial Pain and PropRANOlol
Purpose: Primary: To evaluate the efficacy of extended-release (ER) propranolol compared to placebo in the reduction of a pain index in patients with temporomandibular disorder (TMD).
- Trial name
- SOPPRANO (NCT02437383)
- Testing
- Propranolol ER
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of North Carolina, Chapel Hill
Infantile Hemangioma
Assessing the Impact of Dosage Frequency of Propranolol on Sleep Patterns in Patients With Infantile Hemangiomas
The purpose of this study is to assess the baseline sleep pattern disruption for patients starting oral propranolol at the standard BID dosing regimen compared to the control (timolol) group and to determine if there is a…
- Trial name
- NCT05479123
- Testing
- Propranolol three times a day, Propranolol twice a day, Timolol
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- The University of Texas Health Science Center, Houston
Hemangioma
Corticosteroids With Placebo Versus Corticosteroids With Propranolol Treatment of Infantile Hemangiomas (IH)
This is a prospective randomized, double-blind study to compare the clinical efficacy of infantile hemangioma treatment using propranolol with corticosteroids as compared to therapy with corticosteroids and placebo.
- Trial name
- NCT01074437
- Testing
- Prednisolone (Corticosteroid), Propranolol
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Seattle Children's Hospital
Smoking Cessation
Memory Reconsolidation Blockade as a Novel Intervention for Nicotine Dependence
Smoking is the leading cause of preventable morbidity and mortality in the US. While approximately 70% of smokers attempt to quit each year, only 5-15% maintain abstinence for 12 months, even with effective pharmacological and…
- Trial name
- SCP (NCT00916721)
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hemangioma
The Safety and Efficiency of Propranolol as an Initial Treatment for Pediatric Hemangioma
The purpose of this study is to determine the safety and efficiency of Propranolol as an initial treatment for pediatric hemangioma.
- Trial name
- NCT01908972
- Testing
- Prednisolone, Propranolol
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Hospital
Alcohol Dependence, PTSD
Neuromodulation of Trauma Memories in PTSD & Alcohol Dependence
The purpose of this study is to examine the effect of propranolol versus placebo on craving, distress and cue reactivity to trauma and alcohol cues.
- Trial name
- NCT01055171
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Hemangioma of Infancy
Propranolol Versus Prednisolone for Treatment of Symptomatic Hemangiomas
Hemangiomas are relatively common lesions in infants. Most go away spontaneously after one year of life and do not need treatment.
- Trial name
- NCT00967226
- Testing
- propranolol, Prednisolone
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Nancy Bauman
Obstructive Sleep Apnea
Propranolol for Sleep Apnea Therapy
The primary objective of this study is to test whether a beta blocker, propranolol, lowers the overnight heart rate sleep in obstructive sleep apnea (OSA) during CPAP withdrawal.
- Trial name
- ProSAT (NCT03049306)
- Testing
- Propranolol Oral Tablet
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Johns Hopkins University
Major Depressive Disorder
A Study of LY2216684 in Healthy Participants Receiving Albuterol or Propanolol
The purpose of this study is to determine the effect of LY2216684 on heart rate of participants receiving Albuterol and Propranolol. Information about any side effects that may occur will also be collected.
- Trial name
- NCT01263197
- Testing
- LY2216684, albuterol, propranolol
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Cocaine Dependence
Beta-blockade Effects on Memory for Cocaine Craving
The purpose of this study is to examine the effects of propranolol versus placebo on responses to cocaine cues in cocaine dependent individuals.
- Trial name
- NCT00830362
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medical University of South Carolina
Sickle Cell Disease
Study of Propranolol as Anti-Adhesive Therapy in Sickle Cell Disease (SCD)
An open label, prospective, randomized cross-over phase II study in up to 60 sickle cell patients who are either homozygous for Hb S or have HbSB0 thalassemia.
- Trial name
- NCT01077921
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Laura M. De Castro, MD
Post-Traumatic Stress Disorder
Effectiveness of Propranolol For Treating People With Post-Traumatic Stress Disorder
This study will evaluate the effectiveness of propranolol in reducing symptoms of distress in people with post-traumatic stress disorder.
- Trial name
- NCT00648375
- Testing
- Propanolol, Cognitive therapy workbook
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Weill Medical College of Cornell University
Post-traumatic Stress Disorder
Perioperative Propranolol in Patients With Post Traumatic Stress Disorder (PTSD)
Understanding what treatments may facilitate perioperative care of Veterans with posttraumatic stress disorder (PTSD) is of great importance to the U.S. health care system.
- Trial name
- NCT01555554
- Testing
- Propranolol Hydrochloride
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of California, San Francisco
Infantile Hemangioma
Study to Demonstrate the Efficacy and Safety of Propranolol Oral Solution in Infants With Proliferating Infantile Hemangiomas Requiring Systemic Therapy
There is an unsatisfied medical need for a first-line treatment of proliferating IHs with a good benefit/risk profile. Based on the recent findings of encouraging results obtained with propranolol in a series of infants with…
- Trial name
- NCT01056341
- Testing
- Propranolol
- Where
- 59 sites in United States, Australia and 14 more
- Volunteers
- 512 people
- Sponsor
- Pierre Fabre Dermatology
Pregnancy, Prolonged
Propranolol Rescue of Prolonged Labor
A double-blind placebo controlled randomized trial comparing cesarean delivery rates in women given IV propranolol versus placebo for treatment of prolonged labor.
- Trial name
- PROPEL (NCT04299438)
- Testing
- Propranolol Hydrochloride, Saline
- Where
- 2 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Lisa Levine
Primary Lymphedema
Propranolol Dose Escalation in Lymphedema in Patients
This is a study to investigate the safety and efficacy of propranolol in the treatment of patients with primary lymphedema. The primary goal is to assess patient tolerability of increasing doses of propranolol.
- Trial name
- NCT02595996
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Columbia University
Orthostatic Intolerance, Postural Tachycardia Syndrome
Effect of Exercise in OI
The main limitation patients with orthostatic intolerance (OI, or postural tachycardia syndrome, POTS) have to exercise is related to their increase in heart rate when standing.
- Trial name
- NCT00770484
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Vanderbilt University