Clinical trials: Prophylaxis
Behavior Change Interventions
Monocular-Camera-Based Mobile Exergame for Type 2 Diabetes Prevention
Exergames have demonstrated potential as effective interventions for promoting physical activity and preventing type 2 diabetes (T2D), particularly among older adults.
- Trial name
- NCT06950528
- Testing
- Control group, Kinect group, Monocular group
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Fall Risk Factors, Fall Prevention
Effects of a Fall Preventive Exercise Program on Intrinsic Fall Risk Factors in Healthy Older Adults.
Background With increasing age neuromuscular deficits (e.g., sarcopenia) may result in impaired physical performance and an increased risk for falls.
- Trial name
- NCT01906034
- Testing
- Exercise with supervision, Home-based without supervision
- Where
- Germany
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Potsdam
HIV/AIDS, Mobile Health
Evaluation of a Multi-Component Intervention to Support HIV Testing and Linkage to Services Among MSM in Peru
This study is testing a new program designed to improve access to HIV testing and help connect people with available treatment or prevention services, based on their test result.
- Conditions
- HIV/AIDS, Mobile Health, Feasibility Studies, Qualitative Research
- Trial name
- MERCURY (NCT07074899)
- Testing
- Multi-component HIV testing and linkage-to-services intervention
- Where
- 2 sites in Peru
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Adolescent Behavior, Interpersonal Relationships
It's Your Game: An Innovative Approach to Preventing Teen Dating Violence
The purpose of this study is to evaluate Me \& You: Building Healthy Relationships, a classroom- and computer-based healthy relationships and dating violence prevention curriculum for 6th grade students, in a large, urban public…
- Conditions
- Adolescent Behavior, Interpersonal Relationships, Domestic Violence, Physical Violence
- Trial name
- NCT03482687
- Testing
- Me & You: Building Healthy Relationships
- Where
- United States
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Aging
The Role of Sirolimus in Preventing Functional Decline in Older Adults
Aging is associated with progressive impairment of tissue and organ function, resulting in increased susceptibility to chronic disease, frailty and disability.
- Trial name
- NCT05237687
- Testing
- Sirolimus
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Irina Timofte
Post Traumatic Stress Disorder
Implementation of a Post-traumatic Stress Disorder PREvention Program Within the French ARmy
Post-Traumatic Stress Disorder (PTSD) is a mental health condition that's triggered by a terrifying event perceived as a life threatening - either experiencing it or witnessing it.
- Trial name
- PREPAR (NCT05094531)
- Testing
- Primary prevention programm
- Where
- France
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Obesity
Mobility & Vitality Lifestyle Program
MOVE UP is a weight management program for adults 60-75 in community settings led by trained community health workers.
- Trial name
- MOVE UP (NCT02657239)
- Testing
- MOVE UP
- Where
- United States
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Tobacco Use Cessation, Addiction
An Evaluation of the Tobacco Prevention Toolkit Healthy Futures: Alternative-to-Suspension Vaping Intervention
The Healthy Futures: Alternative-to-Suspension Curriculum is a free, online curriculum developed to educate students and provide them with resources to quit tobacco/nicotine use.
- Trial name
- NCT06483412
- Testing
- Healthy Futures: Alternative-to-Suspension Curriculum
- Where
- United States
- Volunteers
- 2,540 people, healthy volunteers welcome
- Sponsor
- Stanford University
Osteoporosis
High Intensity Strength Training & Bone Mineral Density in Young Women
The current guidelines emphasize the prevention of bone loss, by building up bone mass in young age, as one of the most important measures to reduce the incidence of osteoporosis.
- Trial name
- NCT01482130
- Testing
- Heavy, explosive strength training, recommendations
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Risk Factor
Motivational Interviewing to Increase PrEP Uptake (MI-PrEP)
The purpose of this study is to test a counseling program for Black women at high risk for HIV
- Trial name
- MI-PrEP (NCT03592719)
- Testing
- Experimental Intervention (MI-PrEP), Enhanced Treatment as Usual (E-TAU)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Miami
Dermatitis, Knowledge, Attitudes, Practice
Impact of Combining Incontinence-associated Dermatitis Prevention and Management Course and Directive Wheel Chart
Background: Knowledge, attitudes, and behaviors regarding the prevention and care of incontinence-associated dermatitis (IAD) need to be enhanced through educational training.
- Trial name
- NCT06835192
- Testing
- Experimental group, Control Group
- Where
- Taiwan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Sexually Transmitted Diseases
HIV Prevention for African American Teens
AFIYA aims to reduce both the risk of Sexually Transmitted Infections (STIs) and HIV in young African American females through a culturally and gender appropriate intervention (group sessions) coupled with an individualized HIV…
- Trial name
- NCT00279799
- Testing
- Afiya HIV Prevention Intervention
- Where
- 3 sites in United States
- Volunteers
- 701 people, healthy volunteers welcome
- Sponsor
- Emory University
Ataxia
Fall Prevention in a Geriatric Nursing Home Setting Using the Music of Nolwenn Leroy
Falls are the largest cause of death in the elderly and those with dementia have even a higher incidence of falling. The purpose of this study is to determine whether listening to the Music of Nolwenn Leroy is effective in fall…
- Trial name
- NCT00272272
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Carrick Institute for Graduate Studies
Sarcopenia, Frailty
Sarcopenia Prevention With a Targeted Exercise and Protein Supplementation Program
Physical inactivity and protein malnutrition have been implicated to be key and modifiable causes of enhanced muscle mass loss among seniors.
- Conditions
- Sarcopenia, Frailty, Malnutrition; Protein, Fall
- Trial name
- STRONG (NCT03417531)
- Testing
- Protein Supplement, Protein-free Supplement, Active Exercise
- Where
- 2 sites in Switzerland
- Volunteers
- 801 people, healthy volunteers welcome
- Sponsor
- University of Zurich
HIV Infections, Sexually Transmitted Diseases
Evaluation of Many Men, Many Voices, An STD/HIV Prevention Intervention for Black MSM
The purpose of this program evaluation is to determine whether the "Many Men, Many Voices" HIV/STD prevention intervention is effective in reducing HIV sex risk behaviors and increasing HIV testing among African-American men who…
- Trial name
- 3MV (NCT00137631)
- Testing
- Many Men, Many Voices (3MV)
- Where
- United States
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Breast Cancer
Human Breast Tissue Bioavailability of Topically Applied Limonene
The overall objective of this project is to determine the safety and breast tissue bioavailability of limonene following massage application of limonene containing massage oil to the breast.
- Trial name
- NCT01459172
- Testing
- limonene containing massage oil
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Adolescents and Children, Axial Elongation
Naked Eye 3D Vision Training for the Prevention and Control of Myopia in Adolescents and Children
The study used children aged 6-18 as subjects to evaluate the efficacy and safety of naked eye 3D vision training for the prevention and control of myopia in adolescents.
- Conditions
- Adolescents and Children, Axial Elongation, Naked Eye 3D Vision Training, Visual Function
- Trial name
- NCT05468775
- Testing
- Naked eye 3D vision training
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Influenza, Virus Diseases
Safety of and Immune Response to Recombinant Live-Attenuated Influenza H6N1 Virus Vaccine Vaccine
In the 20th century, influenza pandemics occurred in 1918, 1957, and 1968, and were associated with significant morbidity and mortality.
- Trial name
- NCT00734175
- Testing
- H6N1 Teal HK 97/AA ca recombinant vaccine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
SARS-CoV-2, Coronavirus
Personalized Health Education Against the Health Damage of Novel Coronavirus (COVID-19) Outbreak in Hungary
The additional effect of personalized health education compared to general education following the internationally accepted principles will be evaluated in the prevention of the serious course of the novel coronavirus infection.
- Conditions
- SARS-CoV-2, Coronavirus, COVID-19, 2019-nCoV
- Trial name
- PROACTIVE-19 (NCT04321928)
- Testing
- Personalized health education, General health education
- Where
- Hungary
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- University of Pecs
HIV Prevention, Transgender Health
Study of Truvada for HIV Pre Exposure Prophylaxis Using Daily Directly Observed Therapy to Look at Potential Interactions Between Truvada and Hormone Therapy
Truvada (Emtricitabine or FTC and tenofovir disoproxil fumarate or TDF) has been approved for HIV prevention since 2012. Drug concentrations after receipt of oral Truvada for HIV Pre Exposure Prophylaxis (or PrEP) appeared to be…
- Trial name
- I-BrEATHe (NCT04050371)
- Testing
- 200 mg emtricitabine and 300 mg tenofovir disoproxil fumarate
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco