Clinical trials: Propionibacterium
Acne
Evaluation of the Role of Propionibacterium Acnes in the Inflammatory Lesions Associated With Acne Vulgaris
The purpose of this study is to determine the response of acne patients and healthy control patients to the P. acnes bacteria. Half a tube of blood will be drawn from all participants to determine whether or not they have…
- Trial name
- NCT01929057
- Testing
- Skin biopsy, Blood draw
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Surgical Site Infection
Topical Treatment and Prevalence of P. Acnes
This study is about preventing surgical site infections of the shoulder. We hope to learn if clindamycin alone, benzoyl peroxide alone, or clindamycin and benzoyl peroxide together can affect growth of Propionibacterium acnes in…
- Trial name
- NCT03257202
- Testing
- Clindamycin 1% Gel, Benzoyl peroxide 5% gel, BenzaClin 5%-1% Topical Gel
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Acne
Evaluation and Detection of Facial Propionibacterium Acnes Bacteria and Phage
This multi-center, outpatient study will extract and evaluate the presence of facial P. acnes bacteria and phage strains using pore strips on up to 400 human subjects.
- Trial name
- NCT03009903
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- MBcure Ltd
Acne Vulgaris
A Phase 1 Study Evaluating Safety and Tolerability of NVN1000 Gel
This is a 2 week Phase 1 study of SB204 (NVN1000 Gel) in healthy adult volunteers with elevated Propionibacterium acnes (P. acnes) counts. Subjects will apply NVN1000 4% Gel or Vehicle Gel twice daily to their face.
- Trial name
- NCT01844739
- Testing
- NVN1000 4% Gel, Vehicle Gel
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Novan, Inc.
Vitamin B12 Absorption
Bioavailability of Vitamin B12 in Bread Using Fermented Faba Bean as B12 Source in Healthy Volunteers (BeanBread)
Vitamin B12 is naturally present in animal products, but it could be added to plant-based products through fermentation using the Propionibacterium freudenreichii bacterium.
- Trial name
- NCT06096298
- Testing
- Vitamin B12 bread, Control bread
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Acne Vulgaris
Acne Vulgaris Related Microbiology and Serology
This will be an investigation to determine the quality of the serological immune responses against Propionibacterium acnes (P. acnes) in acne patients compared to healthy individuals.
- Trial name
- NCT04056598
- Testing
- Study of humoral immunity
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sanofi
SAPHO Syndrome
Immune Response in the SAPHO Syndrome
The aetiology of SAPHO syndrome seems to involve genetic, infectious and immunological components. The investigators examined innate and adaptative immune responses in SAPHO syndrome as compared with psoriatic arthritis and…
- Trial name
- NCT01688219
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acne Vulgaris
BPX-01 Minocycline 1% Topical Gel for Reduction of Propionibacterium Acnes
This is a Phase 2a study which is being conducted in healthy volunteers in order to evaluate the comparative reduction of Propionibacterium acnes in-vivo following once daily topical administration of BPX-01 Minocycline 1%…
- Trial name
- NCT02709096
- Testing
- BPX-01, 1% Topical Gel, BPX-01 Vehicle Gel
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- BioPharmX, Inc.