Clinical trials: Propofol Target Controlled Infusion
Spinal (Fusion) Surgery, Total Intravenous Anesthesia
Comparison of Hemodynamic Responses During Anesthesia Induction Using Eleveld and Schnider
This randomized prospective study aims to compare the effects of two target-controlled infusion models, the Schnider and Eleveld models, on anesthetic depth and hemodynamic responses during anesthesia induction in adult patients…
- Conditions
- Spinal (Fusion) Surgery, Total Intravenous Anesthesia, Target Controlled Infusion of Propofol, Anesthesia Depth Monitoring
- Trial name
- NCT07586189
- Testing
- TCI Propofol Injection Models- Eleveld, TCI Propofol Injection Schnider
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Kyphoplasty, Prone Position
TCI Versus Manual TIVA for Sedation During Prone Kyphoplasty: Effects on Respiration, Recovery, and EEG
This single-center, prospective, observational study compares target-controlled infusion (TCI) versus manually administered total intravenous anesthesia (TIVA) for sedation in patients undergoing kyphoplasty in the prone…
- Conditions
- Kyphoplasty, Prone Position, Target Controlled Infusion of Propofol, End Tidal Carbon Dioxide
- Trial name
- NCT07745348
- Testing
- Target controlled infusion of propofol, non invasive ETCO2 monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Propofol Target-controlled Infusion, Desflurane
Effect of Desflurane v/s Propofol on the Optic Nerve Sheath Diameter
effect of propofol vs desflurane on ONSD
- Conditions
- Propofol Target-controlled Infusion, Desflurane, Optic Nerve Sheath Diameter
- Trial name
- ONSD (NCT07359508)
- Testing
- Desflurane, Propofol (Group P)
- Where
- India
- Volunteers
- 146 people
- Sponsor
- All India Institute of Medical Sciences
Throid Surgery, Airway Complication of Anaesthesia
Comparison of the Effects of Total Intravenous Anaesthesia With Target-Controlled Infusion (TCI) and Inhalation Anaesthesia on Airway Complications During Extubation and in the Early Postoperative Period in Thyroidectomy Surgery
Thyroid surgery is one of the most complex operations in the head and neck region due to its close relationship with anatomical structures and the high risk of recurrent laryngeal nerve injury.
- Conditions
- Throid Surgery, Airway Complication of Anaesthesia, Coughing Responses at Tracheal Extubation, Laryngospasm on Emergence
- Trial name
- NCT07325669
- Testing
- tıva
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- dilara gocmen
Endoscopic Submucosal Dissection, Target Controlled Infusion of Propofol
Comparison of the Effects of Target-Controlled Infusion Method and Manual Propofol Administration on Respiratory Function, Recovery, and Electroencephalogram in Endoscopic Submucosal Dissection Cases
Endoscopic submucosal dissection (ESD) has become widely used as a minimally invasive alternative for the resection of early-stage gastrointestinal neoplasms.
- Conditions
- Endoscopic Submucosal Dissection, Target Controlled Infusion of Propofol, Endoscopy Unit, Respiratory Complications
- Trial name
- NCT07305857
- Testing
- manuel propofol and target controlled infusion propofol
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Intensive Care Unit Sedation, Sedation
A Comparative Study of Eleveld and Schnider Pharmacokinetic Models for Target-Controlled Infusion of Propofol in Sedation of Mechanically Ventilated ICU Patients
This prospective observational study aims to compare the clinical performance of two target-controlled infusion (TCI) models, Eleveld and Schnider, for propofol sedation in mechanically ventilated intensive care unit (ICU)…
- Conditions
- Intensive Care Unit Sedation, Sedation, Target Controlled Infusion of Propofol
- Trial name
- NCT07239687
- Testing
- propofol, TCI Propofol Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Hacettepe University
Target Controlled Infusion of Propofol
Validation Study of Covariates Model (VaSCoM) for Propofol
Anaesthesia for surgical procedures can be provided using a continuous infusion of intravenous drug. The most commonly used drug for this technique is propofol.
- Trial name
- VaSCoM (NCT01492712)
- Testing
- Propofol
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Golden Jubilee National Hospital
Propofol-anaesthesia Via Target-controlled Infusion
The Effect of Different End-tidal Carbon-dioxide Levels on Cerebral CO2 Vasoreactivity and the Stiffness of Systemic Arteries During Propofol Anesthesia
Purpose: The purpose of this study is to examine the effect of different carbon-dioxide concentrations on cerebral CO2 sensitivity and the resistance and stiffness of systemic arteries during anesthesia with target-controlled…
- Trial name
- NCT02203097
- Testing
- Partial pressure of CO2 at the end of an exhaled breath, Propofol
- Where
- Hungary
- Volunteers
- 25 people
- Sponsor
- University of Debrecen
General Anesthesia, Propofol Target-controlled Infusion
Effects of Epidural Local Anesthetics on Propofol Induction
The investigators designed a prospective, randomized, placebo-controlled study to determine whether thoracic epidural anesthesia(TEA) with different local anesthetics has different influences on the propofol dose during induction.
- Conditions
- General Anesthesia, Propofol Target-controlled Infusion, Thoracic Epidural Anesthesia
- Trial name
- NCT02000973
- Testing
- Lidocaine, Bupivacaine, Ropivacaine
- Volunteers
- 80 people
- Sponsor
- First Hospital of China Medical University
General Anesthesia, Propofol Pharmacodynamics
Neuronal Inertia in Propofol Anesthesia
Loss and recovery of consciousness during propofol anesthesia seem to be mediated by different mechanisms beyond the actual effect-site concentration of anesthetic drug.
- Conditions
- General Anesthesia, Propofol Pharmacodynamics, Propofol Target Controlled Infusion, Loss of Consciousness and Recovery of Consciousness
- Trial name
- INERTIA (NCT01962285)
- Testing
- propofol targel controlled infusion
- Where
- Chile
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Propofol, Target Controlled Infusion
Propofol TCI Administered by Gastroenterologists During Endoscopy: a Randomized Double Blind Controlled Study
Many studies address safety and effectiveness of non-anesthesiologist propofol sedation (NAPS) for GI endoscopy. Target Controlled Infusion (TCI) is a sophisticated tool for providing optimal sedation regimen and avoiding under…
- Conditions
- Propofol, Target Controlled Infusion, Moderate Sedation, Gastrointestinal Endoscopy
- Trial name
- PropTCI/2012 (NCT01941888)
- Testing
- Propofol, Midazolam, Target Controlled Infusion
- Where
- 2 sites in Italy
- Volunteers
- 140 people
- Sponsor
- Ospedale San Raffaele
General Anaesthesia, Propofol
Blood Propofol Measurement During Anaesthesia Using Propofol Target Controlled Infusion
Propofol is a commonly used agent for sedation and anaesthesia in the intensive care unit and the operating room. The pharmacokinetics of propofol are difficult to predict in patients not conforming to the norms in which the…
- Conditions
- General Anaesthesia, Propofol, Target Controlled Infusion, Pharmacokinetics
- Trial name
- NCT01549639
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust