Clinical trials: Proportional Assist Ventilation
Respiratory Failure
Sleep Quality in Mechanically Ventilated Patients
Patients requiring mechanical ventilation in the ICU will undergo three consecutive nights of polysomnography to record sleep patterns while receiving three modes of mechanical ventilation; Proportional assist ventilation (PAV)…
- Trial name
- NCT01410149
- Testing
- PAV, PSV, ACV
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Mechanical Ventilation
Proportional Ventilation and Ventilatory Synchronism
Synchronism of gas flow delivered by the ventilator and muscular effort of the patient will be studied during two kinds of ventilation.
- Trial name
- NCT00133939
- Testing
- Mechanical ventilation
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Healthy
Flow Proportional Pressure Support in Volunteers
Flow proportional pressure support (FPPS) is a new mode of spontaneous breathing assistance. In patients with increased respiratory resistance the role of FPPS in comparison with the pressure support assist breathing mode is…
- Trial name
- NCT00866541
- Testing
- artificial increased resistance (flow proportional pressure support)
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Weaning Mode Comparison
PAV vs Assist Control After Failed SBT
The primary aim of this research is to determine the feasibility of conducting a randomized controlled trial comparing two ventilation modes in patients admitted to the ICU who require mechanical ventilation.
- Trial name
- NCT02773433
- Testing
- Proportional Assist Ventilation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Louisville
Chronic Obstructive Pulmonary Disease
Comparative Effects of Different Noninvasive Ventilation Mode on Neural Respiratory Drive in Recovering AECOPD Patients
Background: The efficiency of Neural respiratory drive (NRD)expressed by a ratio of ventilation to the diaphragm electromyogram (EMGdi) decreases in patients with COPD .Improving the neural respiratory drive efficiency of COPD…
- Trial name
- NCT01782768
- Testing
- noninvasive positive pressure ventilation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Respiratory Failure
Comparative Effects of Variable Pressure Support, NAVA and PAV
Experimental animal data suggest that increasing breathing pattern variability in mechanical ventilation could be beneficial. Variable ventilation can be induced through the following modes: Neurally Adjust Ventilatory Assist…
- Trial name
- NCT02499276
- Testing
- PSV, NAVA, PAV, Variable-PSV
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Critical Illness, Mechanical Ventilation
"NAVA-PAV" Study: a Cross-over Comparative Study of 2 Advanced Modes
Neurally adjusted ventilatory assist (NAVA) and Proportional Assist Ventilatory Plus (PAV +) are new modes of mechanical ventilation that delivers ventilatory assist in proportion to the electrical activity of the diaphragm for…
- Conditions
- Critical Illness, Mechanical Ventilation, Intensive Care, Ventilation Weaning
- Trial name
- NCT01607723
- Testing
- NAVA ventilatory mode, PAV+ ventilatory mode
- Where
- France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Montpellier
Acute Respiratory Failure, Covid19
Proportional Open Ventilation (POV) Device and Its Efficacy in Managing Acute Respiratory Failure in COVID-19 Patients
To evaluate the use of Life2000® Ventilator, a novel proportional open ventilation system in critical care use of acute onset of respiratory failure (ARF) and mild to moderate forms of acute respiratory distress syndrome (ARDS)…
- Trial name
- NCT04581161
- Testing
- Life2000® Ventilator
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hill-Rom
Bronchopulmonary Dysplasia
Neurally Adjusted Ventilatory Assist vs Proportional Assist Ventilation
This study aims to assess whether neurally adjusted ventilatory assist or proportional assist ventilation is more effective in infants born prematurely with evolving or established bronchopulmonary dysplasia
- Trial name
- NCT02967549
- Testing
- NAVA, PAV
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- King's College London
Acute Respiratory Failure
Comparison of Proportional Assist Ventilation And Neurally Adjusted Ventilator Assist
In spontaneously breathing mechanically ventilated patients, the adequacy between the patient's demand and the level of respiratory support delivered by the ventilator is a major clinical issue.
- Trial name
- PAVANAVA (NCT02056093)
- Testing
- PSV mode, PAV mode, NAVA
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Pierre and Marie Curie University
Dyspnea
Impact of Proportional Assisted Ventilation on Dyspnea and Asynchrony in Mechanically Ventilated Patients
Rational. The mismatch between the activity of the respiratory muscles and the assistance delivered by the ventilator results in patient-ventilator disharmony, which is commonly observed in ICU patients and is associated with…
- Trial name
- DYS-PAV (NCT02801994)
- Testing
- PAV, Puritan Bennett 980 ventilator
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Respiratory Effort, Proportional Assist Ventilation
Proportional Assist Ventilation Plus and Estimation of Respiratory Effort During the Transition to Spontaneous Ventilation
In intensive care units, many critically ill patients need help from a machine called a ventilator to breathe. Once these patients start to recover, doctors try to gradually reduce this support and help them breathe on their own…
- Conditions
- Respiratory Effort, Proportional Assist Ventilation, Work of Breathing
- Trial name
- PAV+ and WOB (NCT06998927)
- Testing
- Application of Proportional Assist Ventilation Plus (PAV+) at three support levels (20%, 50%, 70%) to assess ventilator-displayed work of breathing and its correlation with physiologic measures.
- Where
- Argentina
- Volunteers
- 35 people
- Sponsor
- Argentinian Intensive Care Society
Respiration, Artificial
Proportional Assist Ventilation vs Pressure Support Ventilation
In this study, we want to compare two different kinds of artificial ventilation to see if one encourages faster weaning from breathing support and if one provides better sleep quality. These artificial ventilation types are: 1.
- Trial name
- NCT00790725
- Testing
- Proportional Assist Ventilation, Pressure Support Ventilation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Massachusetts General Hospital
Mechanical Ventilation Complication, Ventilator-Induced Lung Injury
Driving Pressure Variation: NAVA vs PSV
Assisted ventilation represents, nowadays, the preferred ventilation mode in clinical practice.It has been shown that assisted ventilation modes improve ventilation/perfusion matching, descrease risk of Ventilator induced lung…
- Trial name
- DPNAVA (NCT03719365)
- Testing
- NAVAPSV
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Respiratory Failure, Respiration, Artificial
Proportional Assisted Ventilation and Pressure Support Ventilation in Adult Patients With Prolonged Ventilation
A prospective randomized controlled trial was conducted to collect patients with prolonged mechanical ventilation. Patients were randomly assigned to receive PAV+ or PSV as weaning mode.
- Trial name
- NCT04140682
- Testing
- PAV+ mode, PSV mode
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Critically Ill, Acute Respiratory Failure
Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study
For adult patients with acute respiratory failure requiring invasive mechanical ventilation, does a ventilation strategy using proportional assist ventilation with load-adjustable gain factors (PAV+) result in a shorter duration…
- Trial name
- PROMIZING (NCT02447692)
- Testing
- PSV ventilation strategy, PAV+ ventilation strategy
- Where
- 22 sites in Argentina, Canada and 5 more
- Volunteers
- 575 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Weaning From Mechanical Ventilation
Comparison of Weaning on Pressure Support vs. Proportional Assist Ventilation: A Pilot Study
The study hypothesis is that reducing patient-ventilator asynchrony will reduce time required to wean from mechanical ventilation.
- Trial name
- NCT01666054
- Testing
- PSV, PAV
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Respiratory Failure, Mechanical Ventilation
Proportional Assist Ventilation (PAV) in Early Stage of Critically Ill Patients
To evaluate the effectiveness of high assistance proportional assist ventilation (PAV+) (objective 80% gain) as main ventilatory support in early stage of critically ill patients in comparison with standard volume-assist control…
- Trial name
- NCT01204281
- Testing
- Mechanical ventilation mode (PAV+ vs. ACV)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa