Clinical trials: Prospective Observational Study
Idiopathic Inflammatory Myopathies (IIMs)
Clinical Characteristics and Mechanism Research of Deucravacitinib in the Idiopathic Inflammatory Myopathies
This study aims to explore the clinical characteristics and mechanism of Deucravacitinib in the treatment of idiopathic inflammatory myopathies.Detailed Description: The investigators designed a single center, open-label…
- Trial name
- NCT07564271
- Testing
- Deucravacitinib 6mg po qd
- Where
- China
- Sponsor
- Peking University People's Hospital
Difficult Airway, Difficult Intubation
Airway Ultrasound and PeDiAC Score in Pediatric Patients
This prospective observational study aims to evaluate the relationship between preoperative ultrasonographic airway measurements and the Pediatric Difficult Airway Classification (PeDiAC) score in pediatric patients undergoing…
- Conditions
- Difficult Airway, Difficult Intubation, Airway Assessment
- Trial name
- NCT07694167
- Volunteers
- 70 people
- Sponsor
- Samsun University
Neuromyelitis Optica, Neuromyelitis Optica Spectrum Disorder
Maintenance Plasma Exchange for Neuromyelitis Optica
Neuromyelitis optica (NMO) is an inflammatory disease of the central nervous system that is associated with autoantibodies to aquaporin-4.
- Conditions
- Neuromyelitis Optica, Neuromyelitis Optica Spectrum Disorder, Recurrent Idiopathic Longitudinally Extensive Transverse Myelitis
- Trial name
- MultiPLEX (NCT01500681)
- Testing
- Plasma exchange (PLEX)
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Mayo Clinic
Knee Fractures, Stiffness of Knee, Not Elsewhere Classified
Clinical Results After Judet Quadricepsplasty for Post-traumatic Knee Stiffness
The Post-traumatic Extension Contracture of the Knee (PECK) is a common complication following knee traumas. It is characterized by a restricted Range of Motion (ROM), pain, and discomfort in the affected knee.
- Trial name
- NCT06251765
- Testing
- Clinical scores, Range of Motion
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Niche
Cesarean Scar Defect: a Prospective, Observational Study.
The study is conducted as part of the doctoral thesis of Natalia Mazur-Ejankowska, a medical doctor undergoing specialist training in obstetrics and gynecology at the Department of Obstetrics and Gynecology, Gynecologic Oncology…
- Trial name
- NCT07723157
- Testing
- Transvaginal ultrasonography examination
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Gdansk
Pain
The Effect of Anxiety on Perioperative Pain: Patient and Provider Perception
In this study we will assess the incidence and severity of intraoperative and postoperative pain and determine the effect of preoperative anxiety on intraoperative and postoperative pain incidence.
- Trial name
- NCT04363281
- Testing
- preoperative questionnaire, PACU questionnaire, Postoperative questionnaire
- Where
- Israel
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Exercise, Smart Watch
Evaluating the Role of Step Counts in Predicting Readmission and Mortality
This study investigates the relationship between physical activity, heart rate, and sleep quality with recurrent hospitalizations among discharged oncology patients.
- Conditions
- Exercise, Smart Watch, Quality of Life (QOL), Sleep Quality
- Trial name
- STEP-CANCER (NCT06687330)
- Testing
- Tracking Mobility and Health Data with a Smartwatch in Discharged Oncology Patients to Predict Rehospitalization: A Prospective Study
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Gazi University
Observational Study, Dydrogesterone
Observational Study of Dydrogesterone in Cycle Regularization
Dydrogesterone has been widely used worldwide for various gynecological and obstetric indications: Dydrogesterone is effective in cycle regulation treatment.
- Conditions
- Observational Study, Dydrogesterone, Irregular Menstrual Cycle, Abnormal Uterine Bleeding
- Trial name
- NCT02029144
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Fudan University
Contraception
To Evaluate Compliance to Treatment Regimen (Rate of Deviations From the Prescribed Regimen) in Polish Females Treated With Different Low Dose Oral Contraceptives
Adherence to the dosing scheme is the principal element of Combined Oral Contraceptives efficiency. On the other hand noncompliance seemed to be an inseparable element of any oral treatment.
- Trial name
- DOC (NCT01198444)
- Testing
- EE/DRSP (Yasmin Product Family)
- Where
- Poland
- Volunteers
- 11,884 people
- Sponsor
- Bayer
Isthmocele
Frequency of Isthmocele Following Single- Vs Double-layer Uterine Closure.
The main objective of this study is to compare the frequency of isthmocele after caesarean section according to the type of hysteroraffia performed (single or double layer suture).
- Trial name
- NCT06708234
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Lorenza Driul
Bladder Cancer, Staging
Ultrasound Contrast-Enhanced Accurate Diagnosis of Preoperative Staging of Bladder Cancer
Ultrasound and magnetic resonance imaging (MRI) technologies have become essential tools for the diagnosis and preoperative staging assessment of bladder cancer.
- Conditions
- Bladder Cancer, Staging, Contrast Enhanced Ultrasound
- Trial name
- UCEADP-BCS (NCT06775977)
- Testing
- Contrast Enhanced Ultrasound (CEUS)
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Hernia
Repair of Infected or Contaminated Hernias
This is a prospective, multicenter, interventional, observational, open label, single arm, longitudinal evaluation of ventral incisional hernia repair using LTM in contaminated or infected sites.
- Trial name
- RICH (NCT00617357)
- Testing
- LTM (Strattice Reconstructive Tissue Matrix)
- Where
- 15 sites in United States
- Volunteers
- 83 people
- Sponsor
- LifeCell
Aortic Valve Insufficiency, Regurgitation, Aortic Valve
Aortic Valve Replacement With Trifecta(TM)
The purpose of this study is to confirm the clinical safety and effectiveness of the Trifecta valve.
- Conditions
- Aortic Valve Insufficiency, Regurgitation, Aortic Valve, Aortic Valve Incompetence, Aortic Valve Stenosis
- Trial name
- NCT00475267
- Testing
- Trifecta aortic heart valve
- Where
- 5 sites in Canada
- Volunteers
- 203 people
- Sponsor
- Abbott Medical Devices
Antiplatelet Drug-related Gastrointestinal Injury
Long-term MOno-Antiplatelet Drug Strategy After PerCutanEous CoronAry InterveNtion
The OCEAN (long-term mOn-antiplatelet drug strategy after perCutanEous coronANy intervention) study is the largest prospective multicenter data base to investigate the long-term incidence and prognosis of the use of agents for…
- Trial name
- RESCIND-OCEAN (NCT03725800)
- Where
- 8 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Colorectal Neoplasm, Circadian Rhythm Sleep Disorder
Sleep and Survival in Colorectal Cancer
Objective The objective of the current trial is to investigate the effect of perioperative sleep and circadian rhythm on the natural course of survival among patient diagnosed with colorectal cancer.
- Conditions
- Colorectal Neoplasm, Circadian Rhythm Sleep Disorder, Depression, Quality of Life
- Trial name
- NCT03254836
- Testing
- Standard of care
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Zealand University Hospital
Age-related Volume Deficit in the Mid-face
The Volumizing Effect of Juvéderm VOLUMA® in the Mid-Face
This is a prospective, observational study of the volumizing effect of aesthetic use of Juvéderm VOLUMA® with lidocaine in the mid-face area.
- Trial name
- NCT01559064
- Testing
- Crosslinked hyaluronic acid gel (Juvéderm VOLUMA®)
- Where
- 4 sites in Belgium, Germany and 2 more
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Allergan Medical
Peritoneal Surface Malignancies
The Intraoperative Physiologic Changes of Patients Under Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Cytoreductive Surgery; Prospective Observational Study
The most popular surgical treatment of peritoneal cancer is the type known as hyperthermic intraperitoneal chemoperfusion (HIPEC), a type of cytoreductive surgery for which a significantly high survival rate has been demonstrated…
- Trial name
- NCT02325648
- Testing
- HIPEC cytoreductive surgery
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Airway Complication of Anesthesia, Difficult Intubation
Evaluation of Complications in Airway Management
In the current study researchers aim to evaluate the rate of the complication due to airway management (during intubation or placement of supraglottic airway devices)
- Trial name
- AMC (NCT03550326)
- Testing
- airway management
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Derince Training and Research Hospital
Hip Fractures, Subtrochanteric Fractures
Observational Clinical Study on Elderly Patients With Fracture of the Proximal Femur Treated With the Chimaera Nail
This is an observational, prospective and multicenter clinical investigation that is part of the active materiovigilance plan that Orthofix Srl, in agreement with its Notified Body.
- Conditions
- Hip Fractures, Subtrochanteric Fractures, Intertrochanteric Fractures, Pertrochanteric Fracture
- Trial name
- Chimaera (NCT05197335)
- Testing
- Chimaera short nail (length = 180 mm) in combination with one or two telescopic cephalic screws
- Where
- 8 sites in Italy
- Volunteers
- 206 people
- Sponsor
- Orthofix s.r.l.
Psoriasis
Canadian Humira Post Marketing Observational Epidemiological Study: Assessing Effectiveness in Psoriasis
This was a Canadian post-marketing observational study (PMOS) utilizing a prospective cohort design that compared the real - life effectiveness of adalimumab to topical and traditional systemic agents in the management of…
- Trial name
- Complete-PS (NCT01387815)
- Testing
- Adalimumab
- Where
- 36 sites in Canada
- Volunteers
- 662 people
- Sponsor
- AbbVie (prior sponsor, Abbott)