Clinical trials: Prostate
Prostate Cancer
A Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of Oral HRS-5041 in Healthy Subjects
The study was designed to evaluate the pharmacokinetic effects of Rifampicin on HRS-5041 after oral administration of HRS-5041 tablets in healthy subjects.
- Trial name
- NCT07014488
- Testing
- HRS-5041 Tablets, Rifampicin Capsule
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Whole Body Imaging, Prostate
AI Technologies for Enhanced and Celerated High-Field WB-MRI
Single-center, cross-sectional observational study assessing the feasibility of advanced accelerated MRI sequences versus standard ones in terms of image quality, diagnostic reliability, and acquisition time.
- Conditions
- Whole Body Imaging, Prostate, MRI, Lung
- Trial name
- AITECH-MRI (NCT07678320)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Prostatic Neoplasms, Quality of Life
Impact on Quality of Life 3 Years After Diagnosis of Prostate Cancer
To study the quality of life of patients with prostate cancer at a distance from their care at a time when they are supposed to have taken a "normal" life and compared to subjects without cancer prostate of the same age.
- Trial name
- EPICAP-QALY (NCT02854982)
- Testing
- therapeutic management of the prostate Cancer as usual
- Where
- France
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Prostate Cancer
Comparative Study of Radiotherapy Treatments to Treat High Risk Prostate Cancer Patients
In North America, the number of new cases of prostate cancer increases every year. Many efforts have been made to develop more efficient and safer curative treatments for high risk prostate cancer patients.
- Trial name
- NCT02303327
- Testing
- EBRT + HDR brachytherapy boost, Hypofractionated Dose Escalation Radiotherapy, Androgen deprivation therapy
- Where
- 12 sites in Canada
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Prostatic Hyperplasia, Urinary Bladder, Overactive
A Randomized, Double-Blinded, Placebo-Controlled, Two-Way Crossover Study to Investigate the Safety and Toleration of Single Dose Sildenafil in Subjects Receiving Chronic UK-369,0031
To investigate the safety and overall tolerability of co-administration two PDE5 inhibitors UK369,003 and sildenafil
- Conditions
- Prostatic Hyperplasia, Urinary Bladder, Overactive, Erectile Dysfunction
- Trial name
- NCT00814736
- Testing
- UK369,003, sildenafil
- Where
- Singapore
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Pfizer
Breast Cancer, Colon Cancer
Partnership for Healthy Seniors
The Centers for Medicare and Medicaid Services (CMS) has awarded cooperative agreements to 6 sites from across the country (Salt Lake City, UT, Molokai, HI, Houston, TX, Newark, NJ, Detroit, MI, and Baltimore City) to participate…
- Conditions
- Breast Cancer, Colon Cancer, Rectum Cancer, Cervix Cancer
- Trial name
- NCT00379743
- Testing
- Health coordinator (or patient navigator), Educational materials only
- Where
- United States
- Volunteers
- 2,593 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Benign Prostatic Hyperplasia
Is Ejaculation Preservation TURis the Natural Evolution of the "Gold Standard".
evaluation of the impact of apical urethral mucosa sparring with the urethra around the verumontanum on the ejaculatory function and early postoperative urinary incontinence
- Trial name
- NCT06263049
- Testing
- transurethral resection of prostate
- Where
- Egypt
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Prostate Cancer Diagnosis
Can Needle Size Improve Cancer Detection Rate of Transperineal MRI Target Prostate Biopsy Without Affecting Side Effects?
Differences in terms of diagnostic capability and side effects related to the needle caliber used for prostate biopsy sampling in patients with suspected prostate cancer
- Trial name
- TARGET (NCT06420115)
- Testing
- different needle size for prostate biopsy
- Where
- Italy
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Prostate Cancer
Effects of PEEP on Intracranial and Intraocular Pressure in Robot-assisted Laparoscopic Radical Prostatectomy
To investigate the effects of positive end-expiratory pressure (PEEP) on the intracerebral pressure (ICP) and intraocular pressure (IOP) in patients undergoing robot assisted laparoscopic radical prostatectomy (RALRP)
- Trial name
- NCT03031613
- Testing
- PEEP group, ZEEP group
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Prostate Cancer, PSA
PSA Glycomics Assay for Early Detection of Prostate Cancer
The principal aim of this pilot study is to test whether the PSA Glycomics Assay on urine and serum samples can provide insights regarding the disease state of patients with elevated PSA concentrations, as well as to accurately…
- Trial name
- NCT04393376
- Testing
- PSA Glycomics Assay
- Where
- 3 sites in Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Prof.dr. H.P. Beerlage
Prostate Cancer
External Immobilization Compared to Limited Immobilization Using a Novel Real-time Localization System of the Prostate
This prospective study at MAMC evaluates the utility of a rigid pelvic external immobilization compared to limited immobilization using a novel real-time localization system of the prostate.
- Trial name
- NCT01588938
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research Acquisition Activity
Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Chronic Bacterial Prostatitis
Diagnostic Challenges in IC (and Male CPPS)
The etiology and pathogenesis of interstitial cystitis (IC) and its related condition in men, chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) has remained elusive.
- Conditions
- Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Chronic Bacterial Prostatitis, Asymptomatic Inflammatory Prostatitis, Painful Bladder Syndrome
- Trial name
- NCT00672087
- Testing
- Genomic and proteomic biomarker discovery
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Prostate Cancer
Prostate Risk Or Radiology Assessment Non-inferiority Design, Upfront MRI or Risk Calculator in Men With Suspected Prostate Cancer
Thousands of men take a PSA test to investigate whether they have prostate cancer every year. For the vast majority, the test is normal and further investigations are not necessary.
- Trial name
- PRORAND (NCT07422597)
- Testing
- European Study of screening for prostate cancer risk calculator
- Where
- 3 sites in Norway
- Volunteers
- 1,016 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Prostate Cancer
Using Decision Analysis to Enhance Decision-Making Regarding Prostate Cancer Screening
The purpose of this study is to evaluate a new counseling tool for patients deciding whether or not to undergo prostate cancer screening.
- Trial name
- NCT03387527
- Testing
- Prostate cancer decision aid
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Urinary Retention
A Prospective Evaluation of the Catheter Science M3 "Mini Catheter" for Patients With Prostatic
The Catheter Science M3 "Mini Catheter" has been developed for management of urinary retention. This temporary device allows for normal functioning of the external striated sphincter.
- Trial name
- NCT03339076
- Testing
- M3 "MINI CATHETER"
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dr. Gaines W. Hammond Jr. MD FACS
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Formulating Expert Consensus Guidelines in Cancer Care Using the Delphi Method
This study formulates consensus agreement on clinical key elements related to prostate cancer care that are critical for standardization and global reported using a robust Delphi technique, completely remote and electronic.
- Trial name
- NCT05054413
- Testing
- Questionnaire Administration
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer, Prostate Neoplasm
Robotic-arm Assisted 68 Ga PSMA PET/CT Guided Prostate Biopsy Versus MR Directed Cognitive Fusion TRUS Guided Prostate Biopsy (PROBIOP)
The present study aimed to compare the diagnostic accuracy, radiation exposure, complication rates between 68Ga-PSMA PET/CT guided robotic arm assisted prostate biopsy and MRI directed TRUS guided prostate biopsy in PIRADS 4/5…
- Trial name
- PROBIOP (NCT05137561)
- Testing
- PSMA PET guided prostate biopsy, MRI directed TRUS guided prostate biopsy
- Where
- India
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Thoracic Cancer, Ovarian Cancer
Project CADENCE (CAncer Detected Early caN be CurEd)
With existing evidence showing the difference in miRNA expression levels between non-cancer and cancer groups, the investigators assume that levels of DNA methylation, RNA expression as well as protein concentration will also be…
- Conditions
- Thoracic Cancer, Ovarian Cancer, Liver Cancer, Prostate Cancer
- Trial name
- CADENCE (NCT05633342)
- Where
- Singapore
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- MiRXES Pte Ltd
Prostate Cancer
Combined Prostate-specific Antigen, Multi-parametric MRI and Targeted Prostate Biopsy for Prostate Cancer Screening
The study aims to investigate the incidence of prostate cancer among males in Nanjing and whether a combination of PSA, multi-parametric MRI and targeted biopsy is a feasible approach for screening prostate cancer in China.
- Trial name
- NCT04322045
- Testing
- multi-parametric MRI
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Prostate Cancer, Healthy Donors
Comparative Study of Diagnostic and Prognosis Biomarkers of Prostate Cancer in Liquid Biopsy (HOPE)
Constitution of a biological collection within the framework of the establishment of a diagnostic, prognostic and active surveillance test for prostate cancer from long non-coding RNA biomarkers, in 3 cohorts of patients, with…
- Trial name
- HOPE (NCT05141383)
- Testing
- Urine sampling
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Institut Curie