Clinical trials: Prostate Biopsy
Prostate Cancer, Prostate Biopsy
The Impact of Video Education on Pain and Anxiety in Patients Undergoing Transrectal Ultrasonography-Guided Prostate Biopsy
This study aimed to assess the impact of dynamic video education versus static images and verbal instruction on pain perception and anxiety in patients undergoing transrectal ultrasound-guided prostate biopsy (TRUS-Bx).
- Conditions
- Prostate Cancer, Prostate Biopsy, Anxiety
- Trial name
- TRUS (NCT07156747)
- Testing
- Visual Analog Scale, State-Trait Anxiety Inventory, Video
- Where
- Turkey (Türkiye)
- Volunteers
- 223 people
- Sponsor
- Ankara Etlik City Hospital
Prostate Neoplasms, Prostate Biopsy
Effects of Music and Conversation in Prostate Biopsy
The goal of this observational study is to learn about the effects of music and conversation on pain and anxiety levels during Transrectal Ultrasound-Guided Prostate Biopsy.
- Trial name
- TRUS-BX (NCT07006779)
- Testing
- Music intervention, Conversation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bozok University
Prostate Biopsy
Men's Experience of Prostate Biopsy
Men aged over 18 having a first or second diagnostic prostate biopsy at the Royal Marsden NHS Foundation Trust or Epsom General Hospital may be invited to take part in one to one interview within 6 months of having the procedure…
- Trial name
- NCT04274725
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Prostate Biopsy
Impact of Procedure Materials on Patient Anxiety, Depression, and Pain in Prostate Biopsy Consent
The gold standard for diagnosing prostate cancer is an ultrasound-guided prostate biopsy. Despite its low complication rates, the procedure can cause significant stress, discomfort and anxiety in patients.
- Trial name
- NCT06802783
- Testing
- Photo consent
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
68Ga-PSMA PET/CT Guided Prostate Biopsy, Mp-3TMRI Guided Prostate Biopsy
Mp-3TMRI and 68Ga-PSMA PET/CT Guided Prostate Biopsy and Tumor Node Metastasis (TNM) Staging.
BIOPSTAGE is a prospective, non-randomized, diagnostic, multi-cohort investigational study to evaluate the impact of pelvic Multi-parametric 3-Tesla magnetic resonance imaging (mp-3TMRI) and whole-body 68Ga-PSMA PET/CT for…
- Conditions
- 68Ga-PSMA PET/CT Guided Prostate Biopsy, Mp-3TMRI Guided Prostate Biopsy, Prostate Cancer, TNM Staging
- Trial name
- BIOPSTAGE (NCT03465579)
- Testing
- pelvic MRI, 68Ga-PSMA PET/CT
- Where
- 2 sites in Italy
- Volunteers
- 261 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Prostate Biopsy
Evaluation of the Effect on Pain of Attentional Diversion Associated with Hypnotic Induction by Virtual Reality (VRH) in Perioperative Prostate Biopsies Under Local Anesthesia:
The primary objective of the study is to prospectively compare perioperative pain assessed in patients undergoing targeted prostate biopsies, either transrectally or transperineally, under local anesthesia with or without a…
- Trial name
- HYPNOSURG-VR (NCT06691438)
- Testing
- prostate biopsy
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Grenoble
Prostate Cancer XXX, TRANSRECTAL ULTRASOUND-GUIDED PROSTATE BIOPSY
Effect of Lidocaine Gel and Cold Lidocaine Gel on Pain in Patients Who Had Prostate Biopsy With Transrectal Ultrasound
Prostate cancer is one of the most common types of malignancy in men. Transrectal ultrasound-guided prostate biopsy (TRUSG-PBx) is considered the current gold standard method in the diagnosis of prostate cancer.
- Trial name
- NCT06429046
- Testing
- LIDOCAINE GEL, COLD LIDOCAINE GEL
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Breast Cancer, Prostate Cancer
Evaluation Protocols for Isolation of Analytes From Urine for Future Oncology Applications
The aim of this study is to evaluate and optimize protocols for the isolation and analysis of analytes in urine (cell-free nucleic acids, extracellular vesicles and proteins).
- Conditions
- Breast Cancer, Prostate Cancer, Urine, Liquid Biopsy
- Trial name
- URODETECT-WP1 (NCT05453604)
- Testing
- Colli-Pee UAS devices
- Where
- Belgium
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Novosanis NV
Prostate Cancer, Urine
Investigation of Urinary Biomarkers for the Detection of Prostate Cancer
The aim of this study is to investigate and possibly validate urinary biomarkers for prostate cancer. During this study the focus will be on aberrations of selected genes as prognostic or predictive value has been shown for these…
- Conditions
- Prostate Cancer, Urine, Liquid Biopsy
- Trial name
- URODETECT-WP2 (NCT05454371)
- Testing
- Colli-Pee UAS devices
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novosanis NV
Prostate Cancer, Adverse Effects Surgery
TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia.
- Conditions
- Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound
- Trial name
- TPF-LITT (NCT05698576)
- Testing
- TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Urological Research Network, LLC
Prostatic Neoplasms, Prostatectomy
a Study of Combined mpMRI and PSMA PET/CT for Highly Suspicious Patients Performing Radical Prostatectomy Without Biopsy
This is an observational, open, single-arm, prospective, staged entry（based on Fleming's Group-Sequential Design） clinical study The Goal is to evaluate the feasibility and clinical value of direct robot assisted laparoscopic…
- Conditions
- Prostatic Neoplasms, Prostatectomy, Prostate Biopsy
- Trial name
- NCT05670691
- Volunteers
- 71 people
- Sponsor
- Fudan University
Evaluate Requirements of 2% Prilocaine in MR-UF Prostate Biopsy
ED50 of Intratecal Prilocaine in Ultrasound Fusion Prostate Biopsy
The aim of the present study was to determine the ED50 and ED90 of intrathecal hyperbaric 2% prilocaine (HP) for patients undergoing ambulatory prostate biopsy via magnetic resonance imaging (MRI)/ultrasound fusion.
- Trial name
- NCT05649020
- Testing
- Dose of prilocaine
- Where
- 2 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Prostate Biopsy
Pain and Anxiety During Transrectal Prostate Biopsy
Many studies have been conducted in the literature to manage pain and anxiety levels for patients undergoing transrectal prostate biopsy.
- Trial name
- NCT05358223
- Testing
- Music, TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Zonguldak Bulent Ecevit University
Patients Scheduled for Prostate Biopsy Because of Increased Serum PSA and/or Abnormal Digital Rectal Examination
Medical Economics of Urinary PCA3 Test for Prostate Cancer Diagnosis
The ultrasound-guided biopsies of the prostate is the validated technique for the diagnosis of prostate cancer, the first human cancer and second leading cause of cancer death.
- Trial name
- NCT01632930
- Testing
- urinary PCA3 test using Progensa® PCA3 assay kit (Gen-Probe)
- Where
- 10 sites in France
- Volunteers
- 962 people
- Sponsor
- Hospices Civils de Lyon
Prostate Biopsy, Antibiotic
Transperineal MRI-TRUS Fusion Guided Prostate Biopsy With vs Without Antibiotic Prophylaxis
Prostate biopsy is indicated in patients with suspected prostate cancer and has been traditionally performed through the rectum using antibiotic prophylaxis.
- Trial name
- NORAPP (NCT04146142)
- Testing
- Transperineal prostate biopsy with or without antibiotic prophylaxis
- Where
- 2 sites in Germany, Norway
- Volunteers
- 550 people
- Sponsor
- Oslo University Hospital
Prostate Cancer, Prostate Biopsy
Administration of Antibiotic Prophylaxis for Transperineal Prostate Biopsy in Cipto Mangunkusumo Hospital
This randomized controlled trial aims to compare the rate of perioperative infection complications in transperineal prostate biopsy between the group that receives prophylactic antibiotic and the group that receives placebo.
- Conditions
- Prostate Cancer, Prostate Biopsy, Perioperative Complication, Bacteriuria
- Trial name
- NCT04985110
- Testing
- Cotrimoxazole
- Where
- Indonesia
- Volunteers
- 78 people
- Sponsor
- Universitas Indonesia
Indication for Prostate Biopsy Due to Suspected Prostate Cancer
PRospective Prostate biOmarker Study
Correlation of a glycoprotein panel with prostate biopsy outcome and PCa aggressiveness
- Trial name
- PROPOSe (NCT03565289)
- Testing
- Blood sample collection
- Where
- 11 sites in Austria, Denmark and 1 more
- Volunteers
- 455 people
- Sponsor
- ProteoMediX AG
Prostate Cancer, Prostatic Neoplasms
Infectious Outcomes of Povidone-iodine Rectal Cleansing Plus Formalin Disinfection of Needle During Prostate Biopsy
The main purpose of this study is to compare the infectious outcomes of intrarectal povidone-iodine cleansing plus formalin disinfection of needle tip during transrectal ultrasound guided prostate biopsy.
- Conditions
- Prostate Cancer, Prostatic Neoplasms, Prostate Biopsy, Prostatitis
- Trial name
- NCT03879486
- Testing
- Intrarectal povidone-iodine cleansing plus formalin disinfection of needle tip during transrectal ultrasound guided prostate biopsy
- Where
- Brazil
- Volunteers
- 1,257 people
- Sponsor
- Hospital de Transplante Doutor Euryclides de Jesus Zerbini
Prostate Cancer Detection, Fusion Prostate Biopsy
Comparison of Prostate Fusion Biopsies With Software and Cognitive
This study evaluates the efficacy to diagnose significant prostate cancer in patients with suspicious lesions in mpMRI (multiparametric magnetic resonance imaging) by comparing prostate biopsies performed by cognitive fusion with…
- Trial name
- NCT04291742
- Testing
- cognitive vs software
- Where
- Spain
- Volunteers
- 804 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Establish the Efficacy Between the Four Schemes in Terms of the Aggressiveness of the Tumors According to the Gleason Classification, Establish the Efficacy Between the Four Schemes in Terms of Morbidity Associated With the Technique
Impact of Magnetic Resonance and Biomarkers for Screening for Prostate Cancer. Cost-effectiveness Analysis
Objectives: To establish if there are differences between an ultrasound-guided transrectal prostate biopsy (BPTE) and a transperineal prostatic biopsy (BPTP) with and without a multiparametric Magnetic Resonance (RMmp) in…
- Conditions
- Establish the Efficacy Between the Four Schemes in Terms of the Aggressiveness of the Tumors According to the Gleason Classification, Establish the Efficacy Between the Four Schemes in Terms of Morbidity Associated With the Technique, Establish the Efficacy Between the Four Schemes in Terms of the Patient's Subjective Perception Regarding Pain and Quality of Life, Establish the Association of the Tumor Biomarker in the Early Detection and Aggressiveness of Tumors
- Trial name
- RMPBX201801 (NCT04283032)
- Testing
- Multiparametric magnetic resonance
- Where
- Spain
- Volunteers
- 628 people
- Sponsor
- InvestigatorUrologyIBSAL