Clinical trials: Prostate Cancer, suspended
Prostate Cancer
The Plenaxis® Experience Study
Praecis is currently conducting a 2000 patient Experience Study; this is a Phase IV commitment postmarketing safety study in the Food and Drug Administration (FDA) indicated population of patients receiving Plenaxis®.
- Trial name
- NCT00103623
- Testing
- Plenaxis
- Where
- 60 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- PRAECIS Pharmaceuticals Inc.
Prostate Cancer
ClariCore System Used in Transperineal Prostate Biopsy
The overall objective of this study is to acquire ultrasound images, spectral data and prostate tissue biopsy cores using the ClariCore System via a transperineal approach.
- Trial name
- NCT03734575
- Testing
- ClariCore System
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Precision Biopsy, Inc.
Monitor Adverse Events
Trial of Anti-PSMA Designer T Cells in Advanced Prostate Cancer After Non-Myeloablative Conditioning
This is a Phase Ib Pilot study of anti-PSMA designer T cells in metastatic prostate cancer. Subjects will receive escalating doses of T cells, with either low or moderate dose Interleukin 2.
- Trial name
- NCT01929239
- Testing
- Anti-PSMA Designer T Cells
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Roger Williams Medical Center
Metastatic Castration Resistant Prostate Cancer (mCRPC)
Pidnarulex and Talazoparib in Patients With Metastatic Castration Resistant Prostate Cancer
This is phase I, open label, multicentre, dose-escalation study where both doses of talazoparib and pidnarulex will be escalated to define the maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D) for the combination.
- Trial name
- REPAIR (NCT05425862)
- Testing
- Pidnarulex, Talazoparib
- Where
- 5 sites in Australia
- Volunteers
- 48 people
- Sponsor
- Peter MacCallum Cancer Centre, Australia
Castrate-Resistant Prostate Cancer
LIGHT-PSMA-CART in Treating Patients With Castrate-Resistant Prostate Cancer
This is a single center, single arm Phase I study to establish the safety and efficacy of intravenously administered lentivirally transduced LIGHT-PSMA-specific CAR modified autologous T cells (PSMA-CART cells) in patients with…
- Trial name
- NCT04053062
- Testing
- LIGHT-PSMA-CART cells
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Bioray Laboratories
Prostate Adenocarcinoma, PSA Failure
White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA
This phase II trial studies how well white button mushroom supplement works in reducing prostate-specific antigen (PSA) levels in patients with prostate cancer that has come back (recurrent) or has favorable risk and has not…
- Conditions
- Prostate Adenocarcinoma, PSA Failure, PSA Progression, Recurrent Prostate Carcinoma
- Trial name
- NCT04519879
- Testing
- Clinical Observation, Patient Observation, Questionnaire Administration
- Where
- 7 sites in United States
- Volunteers
- 133 people
- Sponsor
- City of Hope Medical Center
Prostate Cancer, Prostate Adenocarcinoma
Utility of Adding MR Fusion to Standard US Guided Prostate Biopsy
The purpose of this study is to utilize this technology in the early detection and staging of pathologic states within prostate cancer patients using the information obtained on mpMRI and serum biomarkers from the patient's blood…
- Trial name
- NCT05064111
- Testing
- TRUS biopsy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Arizona
Prostate Cancer
68Ga-PSMA PET/CT in Prostate Cancer
This is a single-center, multi-arm, open-label, phase III trial in up to 500 patients with biopsy-proven prostate cancer. Participants will receive regular standard of clinical care.
- Trial name
- NCT04684628
- Testing
- 68Ga-PSMA PET/CT
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University of Saskatchewan
Prostate Cancer
Prostasomes as Diagnostic Tool for Prostate Cancer Detection
Prostate cancer is the most frequently diagnosed cancer among men over 50 years old in Western societies, with an incidence that is steadily increasing in most countries.
- Trial name
- NCT03694483
- Testing
- Genetic analysis for the detection of prostasomes
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hackensack Meridian Health
Prostate Cancer, Prostate Neoplasm
Capture of Prostatic Trans-rectal Ultrasound Scans for Research
Through this study the investigators seek to build up a repository of prostate ultrasonography videos and prostate MRI scans to enable research into novel anatomical registration techniques.
- Trial name
- CAPTURE (NCT03321864)
- Testing
- Transrectal ultrasound scan of prostate
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Lung Cancer, Breast Cancer
Telemedicine-mHealth Symptom Cluster Intervention for Advanced Cancer Patients: Finding Our Center Under Stress (FOCUS)
This clinical trial studies whether a telemedicine-mobile health (mHealth) intervention, Finding Our Center Under Stress (FOCUS), improves symptom management in patients with cancer that may have spread from where it first…
- Conditions
- Lung Cancer, Breast Cancer, Prostate Cancer, Multiple Myeloma
- Trial name
- FOCUS (NCT07102212)
- Testing
- mHealth Intervention
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Prostate Cancer, Pet-ct
Clinical Applications of Integrated PET/MR and PET/CT in the Diagnosis and Treatment of Prostate Cancer.
The goal of this study type: observational study (prospective study) is to study prostate cancer occurrence and recurrence, to specifically identify and localize tumor foci at the molecular level at an early stage, to evaluate…
- Trial name
- NCT06355843
- Testing
- 68Ga-PSMA
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8
Robot-Assisted Radical Prostatectomy With or Without Vesicopexy in Patients With Prostate Cancer
This phase III trial compares the effects of robot-assisted radical prostatectomy (RARP) with or without vesicopexy on urinary continence (a person's ability to control their bladder) and quality of life in patients with cancer…
- Conditions
- Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage IIA Prostate Cancer AJCC v8, Stage IIB Prostate Cancer AJCC v8
- Trial name
- NCT04981834
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Radical Prostatectomy
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- University of Southern California
Solid Tumor
A Study of Gene Edited Autologous Neoantigen Targeted TCR T Cells With or Without Anti-PD-1 in Patients With Solid Tumors
This is a first in human, single arm, open label, Phase 1a/1b study to determine the safety, feasibility, and efficacy of a single dose of NeoTCR-P1 T cells in participants with solid tumors.
- Trial name
- NCT03970382
- Testing
- NeoTCR-P1 adoptive cell therapy, nivolumab, IL-2
- Where
- 9 sites in United States
- Volunteers
- 21 people
- Sponsor
- PACT Pharma, Inc.
Prostate Cancer
Application of a Novel Model Based on Plasma cfDNA Assay and MRl Imaging in the Detection of Prostate Cancer
The goal of this diagnostic test is to obtain multiple cell-free DNA （cfDNA） fragment profiles of subjects by whole genome sequencing based on plasma cfDNA, build a prostate cancer prediction model by machine learning, and to…
- Trial name
- NCT06509919
- Testing
- Blood draw and MRI scans
- Where
- 10 sites in China
- Volunteers
- 1,600 people
- Sponsor
- Shanghai Changzheng Hospital
Prostate Cancer, Prostate Neoplasm
Diagnostic Performance of 18F-PSMA-1007 PET/CT in Suspected Prostate Cancer Patient
The diagnostic tools for detecting patients with early prostate cancer are limited due to poor diagnostic performance. The positron emission tomography (PET) combination with the diagnostic radiopharmacy is a non-invasive tool to…
- Trial name
- NCT05422105
- Testing
- 18F-PSMA-1007
- Where
- 2 sites in Taiwan
- Volunteers
- 230 people
- Sponsor
- Primo Biotechnology Co., Ltd
Prostate Cancer, Prostate Cancer Metastatic
Study to Assess Abivertinib in Combination With Abiraterone in Metastatic Castration Resistant Prostate Cancer
This is a phase 2, multicenter, open-label study to evaluate the efficacy of abivertinib with abiraterone in patients with metastatic castration-resistant prostate cancer.
- Trial name
- NCT05361915
- Testing
- Abivertinib, Abiraterone
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Sorrento Therapeutics, Inc.
Prostate Cancer
Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer
Background: The ability to treat early prostate cancer is still limited. Thermal ablation methods are being tested for focal prostate cancer therapy. Researchers want to improve on these methods.
- Trial name
- NCT04808427
- Testing
- TULSA-PRO
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- National Cancer Institute (NCI)