Clinical trials: Prostate Cancer Patients Undergoing Radical Prostatectomy
Stage I Prostate Cancer, Stage IIA Prostate Cancer
Defined Green Tea Catechin Extract in Treating Patients With Localized Prostate Cancer Undergoing Surgery
This randomized pilot phase II trial studies the side effects and how well defined green tea catechin extract works in treating patients with localized prostate cancer undergoing surgery.
- Conditions
- Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
- Trial name
- NCT01340599
- Testing
- defined green tea catechin extract, immunohistochemistry staining method, immunoenzyme technique
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Case Comprehensive Cancer Center
Prostate Cancer Patients Undergoing Radical Prostatectomy
Ejaculatory Behavior and Seminal Vesicle Size During Radical Prostatectomy
The goal of this clinical trial is to learn if recent ejaculation or abstinence before surgery affects seminal vesicle size and dissection-related surgical factors in adult men with prostate cancer undergoing radical…
- Trial name
- PreRP-EJAC (NCT07243795)
- Testing
- Recent Ejaculation, Preoperative Abstinence
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Prostate Cancer
Casodex/Zoladex Biomarkers in Localised Prostate Cancer
To evaluate anti-androgen (bicalutamide) induced biological and molecular changes in prostate comparison to chemical castration induced (goserelin) ones
- Trial name
- NCT00293696
- Testing
- bicalutamide (Casodex), goserelin (Zoladex)
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Tampere University
Resectable Localized Prostate Cancer
HCQ in Resectable Localized Prostate Cancer
This is randomized, double blind, placebo controlled proof of principle (window of opportunity) study of oral hydroxychloroquine in patients with resectable localized prostate cancer.
- Trial name
- NCT06408298
- Testing
- Hydroxychloroquine Sulfate 400Mg Tab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Lionel.D.Lewis, MD
Prostate Cancer
Early DVC Ligation and Urinary Continence Recovery After RARP
The aim of the study is to evaluate the impact of early deep venous complex ligation (eDVCL) in patients affected by clinically localized prostate cancer (PCa) undergoing robot-assisted radical prostatectomy with or without…
- Trial name
- NCT03368378
- Testing
- Early DVC ligation
- Where
- Italy
- Volunteers
- 312 people
- Sponsor
- IRCCS San Raffaele
Prostate Cancer Patients Undergoing Radical Prostatectomy, Prostate CA
Research on PSMA-Targeted Intraoperative Fluorescent Imaging Agents
Phase I: Primary Research Objective: Evaluate the safety, tolerability, and pharmacokinetic characteristics of a single dose of DGPR1008 in healthy subjects.
- Trial name
- DGPR1008 (NCT07101354)
- Testing
- 0.01mg/kg DGPR1008 Injection Dose Group 1 (n=6), 0.02mg/kg DGPR1008 Injection Dose Group 2 (n=6), 0.04mg/kg DGPR1008 Injection Dose Group 3 (n=6)
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Haitao Niu, MD
Prostate Cancer
The Effects of Two Different Ventilation Strategies on Lung Ventilation: An Ultrasonographic Evaluation.
This study will be performed in robotic assisted laparoscopic radical prostatectomy patients in Cerrahpasa Medical Faculty Monoblock Operating Room.
- Trial name
- NCT03740854
- Testing
- Pressure Controlled Ventilation, Volume Controlled Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Istanbul University
Male Erectile Disorder, Prostate Cancer
Vacuum Erection Device in Improving Recovery of Erectile Function in Patients With Prostate Cancer Undergoing Surgery
The purpose of this study is to determine which technique in using a vacuum erection device (VED) is best. Erectile dysfunction (ED) after robotic prostate cancer surgery is a concern for both the surgeon and the patient.
- Conditions
- Male Erectile Disorder, Prostate Cancer, Sexual Dysfunction
- Trial name
- NCT01660152
- Testing
- Sexual Health Inventory for Men (SHIM) questionnaire administration, management of therapy complications, Daily vacuum therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Prostate Cancer
Feasibility of Measuring Exercise's Effects on Molecular Mechanisms of Disease Progression in Prostate Cancer
The investigators aim to evaluate the feasibility of a larger clinical trial assessing an exercise program during the "teachable moment" in patients with prostate cancer and measuring its effect on tumor apoptosis signaling…
- Trial name
- EMMPC (NCT02481648)
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Vancouver Prostate Centre
Prostate Cancer
Pilot Study: Androgen Deprivation Therapy Impact on PSMA-PET Sensitivity in Prostatectomy Staging
This is a pilot, non-randomized, two-cohort interventional study in patients who meet the inclusion criteria, using an FDA- approved androgen deprivation agent for a 3 or 6-week course of treatment prior to standard-of-care RALP…
- Trial name
- PIONEER PSMA (NCT07069465)
- Testing
- flotufolastat F 18, Relugolix 120 MG, Serum PSA and Testosterone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Urology Clinics of North Texas
Prostate Carcinoma
Micro-Ultrasound for the Detection and Localization of Prostate Cancer Tumors in Patients Undergoing Radical Prostatectomy
This trial studies the ability of micro-ultrasound to detect and characterize prostate cancer tumors in patients undergoing radical prostatectomy (removal of the entire prostate and some of the tissue around it).
- Trial name
- NCT04299620
- Testing
- Digital Image Analysis, Radical Prostatectomy, Transrectal Ultrasound
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Adenocarcinoma of the Prostate, Stage I Prostate Cancer
Lycopene in Treating Patients Undergoing Radical Prostatectomy for Prostate Cancer
This randomized phase II trial studies how well different doses of lycopene work in treating patients undergoing radical prostatectomy for prostate cancer.
- Conditions
- Adenocarcinoma of the Prostate, Stage I Prostate Cancer, Stage II Prostate Cancer, Stage III Prostate Cancer
- Trial name
- NCT00450749
- Testing
- therapeutic conventional surgery, laboratory biomarker analysis, lycopene
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer
Comparison Between Conventional and Model-based Infusion Strategy of IV PCA in Patients Undergoing RALP
Comparing postoperative analgesics requirements and complications between conventional and model-based infusion strategy of intravenous patient-controlled analgesia in patients who undergoing robot assisted laparoscopic radical…
- Trial name
- NCT02402621
- Testing
- fentanyl
- Where
- South Korea
- Volunteers
- 111 people
- Sponsor
- Asan Medical Center
Impaired Cognition, Quality of Life
The Assessment of the Feasibility of a Home Based Exercise Programme in the Older Patient Following Major Surgery
The primary aim of this study is to establish if it is possible for patients who have undergone major body surgery to complete a home based exercise training program and complete the assessments required to measure physical and…
- Conditions
- Impaired Cognition, Quality of Life, Surgery, Delirium
- Trial name
- POETold (NCT03064308)
- Testing
- Exercise Programme
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- University of Nottingham
Postoperative Delirium (POD), Prostate Cancer
Preoperative Breathing Exercise Training and Postoperative Delirium After Robotic Radical Prostatectomy
Postoperative delirium is an acute and fluctuating disturbance in attention, awareness, and thinking that may occur after major surgery.
- Trial name
- NCT07766603
- Testing
- Preoperative Deep Breathing Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- ALİ DEMİRTAŞ
Prostate Cancer
Soy Isoflavones in Treating Patients Who Are Undergoing Radical Prostatectomy for Stage I or Stage II Adenocarcinoma of the Prostate
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent or delay the development of early cancer. Soy isoflavones may be effective in delaying the development of early prostate cancer.
- Trial name
- NCT00078923
- Testing
- soy isoflavones, neoadjuvant therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Prostate Cancer
Prospective Study Comparing Extended With Limited Pelvic Lymphadenectomy in Intermediate and High Risk Prostate Cancer Patients Undergoing Radical Prostatectomy
Prostate cancer is currently the second most common cause of cancer death in men in Western countries. Lymphadenectomy is the gold standard procedure for staging pelvic lymph node and is classically indicated in intermediate and…
- Trial name
- LFD (NCT01812902)
- Testing
- Radical Prostatectomy
- Where
- Brazil
- Volunteers
- 260 people
- Sponsor
- University of Sao Paulo
Prostate Cancer (Post Prostatectomy), Urinary Incontinence (UI)
The Effect of Pelvic Floor Muscle Exercises After Radical Prostatectomy
Cancer, a major public health problem worldwide, was one of the leading causes of mortality in 2020, accounting for approximately 10 million deaths.
- Trial name
- NCT07045415
- Testing
- Pelvic Floor Muscle Exercises.
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- KTO Karatay University
Prostate Cancer Patients Undergoing Radical Prostatectomy
Advanced Pelvic Floor Training Program for Prostate Cancer Surgery
Radical prostatectomy is a common and effective treatment for prostate cancer but is associated with urinary incontinence that can persist for several months after surgery and significantly reduce quality of life.
- Trial name
- AFPX (NCT02233608)
- Testing
- Advanced Pelvic Floor Muscle Exercise (APFX)
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- University of Guelph-Humber
Prostate Cancer Patients Undergoing Radical Prostatectomy
Safety and Efficacy Trial of a Targeted PSMA Fluorescent Contrast Agent (DGPR1008) for Intraoperative Imaging of Prostate Cancer
a single-arm, open-label, multi-center study to evaluate safety, tolerability, pharmacokinetics, and the effectiveness of near-infrared fluorescence imaging during surgery.
- Trial name
- DGPR1008 (NCT07024030)
- Testing
- 0.02mg/kg, 0.04mg/kg
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Haitao Niu, MD