Clinical trials: Prostate Cancer Stage
Prostate Cancer
Vaccine Therapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
RATIONALE: Vaccines made from a person's peripheral stem cells may make the body build an immune response to kill tumor cells. PURPOSE: Phase I trial to study the effectiveness of vaccine therapy in treating patients who have…
- Trial name
- NCT00005992
- Testing
- PSA prostate cancer vaccine, therapeutic autologous dendritic cells
- Where
- 2 sites in United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Cancer Survivor, Partner
Lifestyle Behavior Influences Among African American Patients With Stage 0-III Prostate Cancer Survivors and Their Partners
This trial studies the day-to-day stress, social support, and health lifestyle behaviors (such as physical activity and nutrition) in African American patients with stage 0-III prostate cancer survivors and their partners.
- Conditions
- Cancer Survivor, Partner, Spouse, Stage I Prostate Cancer AJCC v8
- Trial name
- NCT04189770
- Testing
- Accelerometer, Ecological Momentary Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Metastatic Castration-resistant Prostate Cancer, Recurrent Epithelial Ovarian Cancer
Study to Assess Safety and Efficacy of AsiDNA in Combination with Olaparib in Participants with Recurrent Solid Tumors
This is a phase 1b/2 open-label, multicenter, basket study to determine the safety, anti-tumor activity, tolerability, and pharmacokinetics /pharmacodynamics of AsiDNA in combination with olaparib in participants with recurrent…
- Conditions
- Metastatic Castration-resistant Prostate Cancer, Recurrent Epithelial Ovarian Cancer, Breast Cancer
- Trial name
- NCT05700669
- Testing
- AsiDNA, Olaparib
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Valerio Therapeutics
Prostate Cancer
Calcitriol and Dexamethasone in Treating Patients With Prostate Cancer Who Have Undergone Surgery or Radiation Therapy
RATIONALE: Calcitriol may help tumor cells develop into normal cells. Dexamethasone may increase the effectiveness of calcitriol by making tumor cells more sensitive to the drug.
- Trial name
- NCT00054522
- Testing
- calcitriol, dexamethasone
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Roswell Park Cancer Institute
Prostatic Neoplasms, Castration-Resistant
Safety & Immunogenicity of JNJ-64041809, a Live Attenuated Double-deleted Listeria Immunotherapy, in Participants With Metastatic Castration-resistant Prostate Cancer
The purpose of this study is to find and evaluate the recommended Phase 2 dose (RP2D) of JNJ-64041809, a live attenuated double deleted (LADD) Listeria monocytogenes (bacteria in which two virulence genes, which encode molecules…
- Trial name
- NCT02625857
- Testing
- JNJ-64041809 (Cohort 1A and 1B), JNJ-64041809 (Cohort 2A and 2B)
- Where
- 6 sites in United States
- Volunteers
- 26 people
- Sponsor
- Janssen Research & Development, LLC
Prostate Cancer
Safety and Tolerability Study of MDV3100 in Combination With Docetaxel in Men With Advanced Prostate Cancer
The purpose of this study is to determine the safety of MDV3100 given in combination with Docetaxel in men with advanced prostate cancer.
- Trial name
- NCT01565928
- Testing
- MDV3100
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Pfizer
Prostate Cancer
A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer
This is a randomized, open-label, three-arm, phase 3 study in men with biochemically recurrent prostate cancer and PSA doubling time ≤ 9 months at the time of study entry.
- Trial name
- NCT03009981
- Testing
- Apalutamide, LHRH Analogue, Abiraterone Acetate
- Where
- 69 sites in United States
- Volunteers
- 504 people
- Sponsor
- Alliance Foundation Trials, LLC.
Prostate Cancer Recurrent, Stage II Prostate Carcinoma
Development of Clinical Assessment Technique Using Multi-radiotracer PET/MR in Prostate Cancer
To development of clinical assessment technique using multi-radiotracer positron emission tomography/magnetic resonance (PET/MR) in prostate cancer to establish the optimal imaging technique of PET/MR using multiple radioactive…
- Conditions
- Prostate Cancer Recurrent, Stage II Prostate Carcinoma, Stage III Prostate Carcinoma
- Trial name
- NCT01938339
- Testing
- PET/MR
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Prostate Cancer, Refractory Cancer
Fatty Acid Synthase Inhibition in Castration Refractory Prostate Cancer
The purpose of this research study is to find out what effects (good and bad) omeprazole and cabazitaxel, or omeprazole and docetaxel, has on participants and their condition.
- Conditions
- Prostate Cancer, Refractory Cancer, Castration Resistant Prostatic Cancer
- Trial name
- FASN (NCT04337580)
- Testing
- Omeprazole 80 mg twice daily
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Prostate Cancer
Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer in Japan
The purpose of this study is to assess the efficacy, tolerability, safety, pharmacokinetic (PK) and dosimetry of 177Lu-PSMA-617, in participants with progressive prostate-specific membrane antigen (PSMA)-positive metastatic…
- Trial name
- NCT05114746
- Testing
- 177Lu-PSMA-617, 68Ga-PSMA-11, Best supportive/best standard of care
- Where
- 8 sites in Japan
- Volunteers
- 94 people
- Sponsor
- Novartis Pharmaceuticals
Prostate Carcinoma, Stage I Prostate Cancer AJCC v8
CT- Versus MRI-Based Planning for High-Dose-Rate Prostate Brachytherapy for Prostate Cancer
This clinical trial studies the safety of a computed tomography (CT) scan, with or without a magnetic resonance imaging (MRI) scan, in planning for high-dose-rate (HDR) prostate brachytherapy treatment in patients with prostate…
- Conditions
- Prostate Carcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8
- Trial name
- NCT07859722
- Testing
- Magnetic Resonance Imaging, Questionnaire Administration
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Prostate Cancer
Oral EPI-7386 in Patients with Castration-Resistant Prostate Cancer
This is a phase I, clinical research study of EPI-7386, an investigational drug being studied as a treatment for patients with prostate cancer. All patients in the study will receive EPI-7386.
- Trial name
- EPI-7386 (NCT04421222)
- Testing
- EPI-7386 (QD), EPI-7386 (BID), Abiraterone acetate
- Where
- 9 sites in United States, Canada
- Volunteers
- 71 people
- Sponsor
- ESSA Pharmaceuticals
Recurrent Prostate Cancer, Stage IV Prostate Cancer
Combination Chemotherapy in Treating Patients With Metastatic or Unresectable Solid Tumors
This phase I trial is studying the side effects and best dose of combination chemotherapy in treating patients with metastatic or unresectable solid tumors.
- Conditions
- Recurrent Prostate Cancer, Stage IV Prostate Cancer, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00058253
- Testing
- tanespimycin, docetaxel
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Cancer Institute (NCI)
Metastatic Castration-resistant Prostate Cancer
Autologous Gamma Delta T Cells to Target Prostate Stem Cell Antigen in mCRPC
This is a phase 1 single center clinical trial for patients with end stage Metastatic Castration Resistant Prostate Cancer who have progressed through standard of care treatment options and are on zoledronate for bone metastases.
- Trial name
- NCT06193486
- Testing
- MSGV1-PSCA-8T28Z, Fludarabine, Cyclophosphamide
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Castration Resistant Prostate Cancer
Phase 1 Study of GEN0101 in Patients With Recurrence of CRPC
This study is designed to evaluate the safety and efficacy of a single injection of GEN0101 in patients with recurrence of castration resistant prostate cancer.
- Trial name
- NCT02502994
- Testing
- GEN0101
- Where
- Japan
- Volunteers
- 12 people
- Sponsor
- Norio Nonomura
Hypofractionated Dose, Prostate Cancer Patients
Hypo Fractionated Versus Conventional IMRT in Unfavorable Intermediate- and High-Risk Prostate Cancer
The aim of the study is 1. Statistical evaluation of patients' characteristics who have intermediate \& high risk localized prostate cancer. 2.
- Trial name
- NCT07489729
- Testing
- Hypofractionated Intensity-Modulated Radiation Therapy, Conventional Intensity-Modulated Radiation Therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Prostate Cancer, Metastatic Castration-resistant Prostate Cancer
Abemaciclib With or Without Atezolizumab for mCRPC
This trial is testing whether a molecularly targeted chemotherapy drug called abemaciclib and an immunotherapy drug called atezolizumab, alone or in combination, are effective in shrinking or preventing the growth of metastatic…
- Trial name
- NCT04751929
- Testing
- Abemaciclib, Atezolizumab
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Dana-Farber Cancer Institute
Prostate Cancer
Study of Erlotinib in Patients With Non-Metastatic Prostate Cancer With a Rising Prostate Specific Antigen (PSA) on Hormone Therapy
The primary objective of this study is to evaluate the effect of erlotinib on the PSA response rate in patients with non-metastatic prostate cancer and a rising PSA on androgen deprivation therapy.
- Trial name
- NCT00148772
- Testing
- Erlotinib (Tarceva)
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Monitor Adverse Events
Trial of Anti-PSMA Designer T Cells in Advanced Prostate Cancer After Non-Myeloablative Conditioning
This is a Phase Ib Pilot study of anti-PSMA designer T cells in metastatic prostate cancer. Subjects will receive escalating doses of T cells, with either low or moderate dose Interleukin 2.
- Trial name
- NCT01929239
- Testing
- Anti-PSMA Designer T Cells
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Roger Williams Medical Center
Prostate Neoplasm
COHORT Trial in Clinical Pelivc Lymph Node Metastatic Prostate Cancer
In local advanced prostate cancer patients with clinically positive metastatic regional lymph node, the optimal treatment is still unanswered.
- Trial name
- NCT03241537
- Testing
- Intensity modulated radiotherapy
- Where
- South Korea
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center