Clinical trials: Prostate Disease
Prostate Cancer
Trial of Anti-PSMA Designer T Cells in Advanced Prostate Cancer After Non-Myeloablative Conditioning
This study tests the safety and tolerability of autologous anti-PSMA gene-modified T cells (designer T cells) in hormone refractory prostate cancer.
- Trial name
- NCT00664196
- Testing
- Gene Modified T Cells
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Roger Williams Medical Center
Prostate Cancer
Biodistribution and Pharmacokinetic Study of 18F-DCFBC Prostate Specific Membrane Antigen Based PET in Patients With Advanced Prostate Cancer
Prostate cancer is the most common cancer among men in the United States. Through early detection and improved local therapies a large number of men will be cured.
- Trial name
- NCT01417182
- Testing
- 18F-DCFBC
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Carcinoma Metastatic to the Bone, Castration Resistant Prostate Cancer
A Positron Emission Tomography/Computed Tomography (PET/CT) Bone Imaging Study in Patients Receiving Enzalutamide for Castration-Resistant Prostate Cancer (CRPC)
The purpose of this study is to evaluate 18F-sodium fluoride positron-emission tomography / computed tomography (18F-NaF PET/CT) imaging as a method for determining treatment response in metastatic bone lesions in patients who…
- Trial name
- NCT02384382
- Testing
- Enzalutamide
- Where
- 5 sites in United States
- Volunteers
- 23 people
- Sponsor
- Pfizer
Localized Breast Cancer, Localized Prostate Cancer
Use of Organic Germanium or Placebo for the Prevention of Radiation Induced Fatigue
Participants will be diagnosed with localized prostate or breast cancer and be scheduled to undergo external beam radiation therapy.
- Conditions
- Localized Breast Cancer, Localized Prostate Cancer, Patients Receiving External Beam Radiotherapy
- Trial name
- NCT00651417
- Testing
- Organic Germanium
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Arizona Oncology Services
Prostate Cancer
Phase 3 Study of ProstAtak® Immunotherapy With Standard Radiation Therapy for Localized Prostate Cancer
The purpose of this study is to evaluate the effectiveness of ProstAtak® immunotherapy in combination with radiation therapy for patients with intermediate-high risk localized prostate cancer.
- Trial name
- PrTK03 (NCT01436968)
- Testing
- Aglatimagene besadenovec + valacyclovir
- Where
- 73 sites in United States, Puerto Rico
- Volunteers
- 711 people
- Sponsor
- Candel Therapeutics, Inc.
Prostate Cancer
A Phase II Study of Ara-C (Cytarabine) in Men With Androgen Independent Prostate Cancer
This is a single-arm, open label phase II trial of the investigational agent, Ara-C (cytarabine), in patients diagnosed with hormone refractory prostate cancer whose disease has progressed on or deemed not suitable for standard…
- Trial name
- SLAP (NCT00480090)
- Testing
- Cytarabine
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University Health Network, Toronto
Solid Tumors and Hematologic Malignancy
An Open-Label, Dose-Escalation Study of INCB054329 in Patients With Advanced Malignancies
This was a study of INCB054329 given to patients with advanced malignancies that were conducted in three treatment groups. Each treatment group had a dose escalation (Part 1) and a dose expansion (Part 3), two of the treatment…
- Trial name
- NCT02431260
- Testing
- INCB054329 Monotherapy
- Where
- 12 sites in United States
- Volunteers
- 69 people
- Sponsor
- Incyte Corporation
Prostatic Hyperplasia
Prescription Event Monitoring in Patients With Benign Prostatic Hyperplasia (BPH)
Study to evaluate the safety profile of Secotex® in the improvement of the symptoms of Benign Prostatic Hyperplasia in real clinical practice
- Trial name
- NCT02244346
- Testing
- Secotex®
- Volunteers
- 811 people
- Sponsor
- Boehringer Ingelheim
Breast Cancer, Colorectal Cancer
Physical Training and Cancer-a Multicenter Clinical Trial
Excessive tiredness (fatigue) is a common problem in cancer patients and can affect quality of life negatively. There is limited knowledge about the physical mechanisms that cause fatigue, and there is no medical treatment.
- Conditions
- Breast Cancer, Colorectal Cancer, Prostate Cancer
- Trial name
- Phys-Can (NCT02473003)
- Testing
- high intensity exercise, low/medium intensity exercise, Behavioral medicine strategies
- Volunteers
- 600 people
- Sponsor
- Uppsala University
Prostate Cancer
Prostate Cancer Upgrading Reference Set
Research repository designed to establish prostate cancer upgrading reference set and development of a risk prediction tool. Repository will include clinical information and biologics on a cohort of 240 men, to predict presence…
- Trial name
- NCT02189486
- Where
- United States
- Volunteers
- 382 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Prostate Cancer
Combination of 68Ga-PSMA PET Data With Magnetic Resonance Spectroscopy Data (MRS) for Evaluating Prostate Cancer
Prostate cancer is the second most common cancer among man and the fourth most occurring over all . Characterization and management of the diagnosed prostate cancer is a challenging task due to its clinically and morphologically…
- Trial name
- NCT04154280
- Testing
- PET/MR scan
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Prostate Cancer
Ultrasound in Treating Patients With Prostate Cancer Confined to the Prostate
RATIONALE: Highly focused ultrasound energy may be able to kill cancer cells by heating the tumor without affecting the surrounding tissue.
- Trial name
- NCT00030290
- Testing
- high-intensity focused ultrasound ablation
- Where
- United States
- Sponsor
- Focus Surgery
Prostate Cancer
Carboplatin-Etoposide Combination in Hormone-Resistant Prostate Cancers
The aim of our study is to assess the efficacy and toxicity of a chemotherapy regimen combining carboplatin and etoposide in patients with metastatic hormone-resistant prostate cancer and neuro-endocrine differentiation.
- Trial name
- NCT00973882
- Testing
- Carboplatin, Etoposide
- Where
- 11 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Leon Berard
Prostate Cancer
Gadoxetate Enhanced Imaging Study to Detect Prostate Cancer
Background: Prostate cancer is the most common cancer type among men. Some prostate cancers respond to hormonal therapy. However, some cell characteristics of other prostate cancers cause it not to respond as well to these…
- Trial name
- NCT01867424
- Testing
- Eovist
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Cancer Institute (NCI)
Sarcopenia, Prostate Cancer
Changes in Body Composition With Patients Under Androgen Deprivation Therapy
This study aimed to evaluate the correlation of change in body composition and oncological outcomes of prostate cancer patients under androgen deprivation therapy(ADT).
- Trial name
- NCT04037488
- Testing
- Inbody 320
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Seoul National University Hospital
Prostate Cancer
Circulating And Intra-Tumoral Chemokines In Patients With Prostate Cancer
Multicentric, observational, prospective, non-interventional study with occasional biological sample collection (serum bank, urine bank and tumor bank)
- Trial name
- CHEMOPROST (NCT02869282)
- Testing
- Blood samples, Urine samples
- Where
- France
- Sponsor
- Institut Bergonié
Prostate Neoplasms
An Safety and Efficacy Study of Abiraterone Acetate in Participants With Advanced Prostate Cancer Who Failed Androgen Deprivation and Docetaxel-Based Chemotherapy
The purpose of this study is to assess the anti-tumor activities and safety of abiraterone acetate in participants with prostate cancer (a disease in which cells in the prostate gland [a gland in the male reproductive system…
- Trial name
- NCT00474383
- Testing
- Abiraterone acetate, Glucocorticoid
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 47 people
- Sponsor
- Cougar Biotechnology, Inc.
Intraoperative Floppy Iris Syndrome, Cataract
Comparing the Efficiency of Two Approaches in Patients at Risk of Developing Intraoperative Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome (IFIS) is a potentially serious cataract surgery complication. IFIS is most commonly associated with the chronic use of tamsulosin and other alpha1-adrenergic receptor antagonists prescribed in…
- Conditions
- Intraoperative Floppy Iris Syndrome, Cataract, Age-related Cataract, Adrenergic Receptor Antagonist Adverse Reaction
- Trial name
- NCT06266962
- Testing
- 1% Atropine drops, Epinephrine
- Where
- Czechia
- Volunteers
- 164 people
- Sponsor
- University Hospital Olomouc
Prostate Cancer
Problem Solving Therapy for Prostate Cancer Spousal Caregivers
Problem-solving therapy programs have been shown to be effective among parents of children diagnosed with cancer. Efforts have been made to apply this same strategy to spouses/significant others of men diagnosed with prostate…
- Trial name
- NCT02085096
- Testing
- Problem-Solving Therapy
- Where
- United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Prostate Cancer
Clinical Management Decisions for Recurrent Prostate Cancer Patients Based on [11C]Acetate PET Scan
When evaluating prostate cancer patients for recurrent disease, computed tomography (CT), and magnetic resonance imaging (MRI) are both highly sensitive methods for detecting lymph nodes, but are not specific as to whether the…
- Trial name
- NCT01777061
- Testing
- [11C]Acetate
- Where
- United States
- Sponsor
- Wendell Yap, MD
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