Clinical trials: Prostate Obstruction
Lower Urinary Tract Symptoms, Voiding Dysfunction
Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods
Background and study aims: The prostate gland sits around the exit of the bladder in men. As men get older, the prostate grows, and this can narrow the exit from the bladder, so that there is restriction of flow.
- Conditions
- Lower Urinary Tract Symptoms, Voiding Dysfunction, Benign Prostate Obstruction, Detrusor Underactivity
- Trial name
- UPSTREAM (NCT02193451)
- Testing
- Urodynamics, Usual care
- Where
- United Kingdom
- Volunteers
- 820 people
- Sponsor
- North Bristol NHS Trust
Benign Prostate Obstruction (BPO)
Enucleation Ratio as a Novel Predictor of Symptomatic Improvement After HoLEP
The goal of this observational study is to determine whether the rate of prostate tissue removed during surgery relative to the preoperative total prostate volume (referred to as the "enucleation ratio") predicts symptomatic…
- Trial name
- NCT07591688
- Testing
- Holmium laser enucleation of prostate (HoLEP)
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Ondokuz Mayıs University
Acute Urinary Retention, Benign Prostatic Hyperplasia
Tamsulosin With or Without Tadalafil for Trial Without Catheter After Acute Urinary Retention Due to Benign Prostatic Hyperplasia
Acute urinary retention is a common emergency in men with benign prostatic hyperplasia. After bladder drainage with a urethral catheter, patients usually undergo a trial without catheter to determine whether they can pass urine…
- Conditions
- Acute Urinary Retention, Benign Prostatic Hyperplasia, Benign Prostatic Obstruction
- Trial name
- TAMS-TAD-TWOC (NCT07654413)
- Testing
- Tamsulosin, Tadalafil
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Beni-Suef University
Prostate Cancer
Stellate Ganglion Block for Hot Flushes in Men Treated With ADT
Androgen deprivation therapy (ADT) is widely used as standard therapy in the treatment of locally advanced and metastatic prostate cancer. Hot flushes and night sweats are one of the main side-effects of ADT.
- Trial name
- NCT02295163
- Testing
- Stellate ganglion block
- Where
- Netherlands
- Sponsor
- Rijnstate Hospital
Bladder Outlet Obstruction
Bladder Outlet Obstruction Observation Using Dynamic Urine Vibration "Holter"
Current gold standard of bladder outlet diagnosis is pressure flow study. This study is invasive time consuming and requires expensive and complex set-up.
- Trial name
- NCT01779349
- Testing
- Dynamic Urine Vibration "Holter"
- Where
- 2 sites in Israel
- Volunteers
- 45 people
- Sponsor
- P. Square Medical Ltd
Bladder Outlet Obstruction
An Open Label Study to Measure Efficacy of Fesoterodine (Toviaz) Post Surgery for Benign Prostatic Hyperplasia
The subjects who have symptoms of overactive bladder (many trips to the bathroom, and urgency with or without the inability to hold your urine until you get to the toilet) are invited to participate in this research study.
- Trial name
- Toviaz (NCT00605319)
- Testing
- Toviaz (Fesoterodine)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Prostate Cancer, Hot Flashes
(SGB) in Men Treated for Prostate Cancer Improve Hot Flashes
Androgen Deprivation Therapy (ADT) is a critical component of advanced prostate cancer treatment but causes numerous adverse effects including decreased bone mass, decreased muscle mass, gynecomastia, erectile dysfunction, loss…
- Trial name
- NCT03796195
- Testing
- .5% Bupivacaine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Northwestern University
Lower Urinary Tract Symptoms
Prostatic Obstruction Investigation Team Multicenter Study
The present is a multicenter, observational study organized by the Prostatic Obstruction Investigation Team (POInT), with a main purpose of looking into the current status and symptom progression of male lower urinary tract…
- Trial name
- POInT (NCT03394651)
- Testing
- Oral medications to treat lower urinary tract symptoms, Minimal invasive transurethral prostate procedures
- Where
- China
- Volunteers
- 11,500 people
- Sponsor
- Changhai Hospital
Benign Prostate Obstruction (BPO), Lower Urinary Tract Symptom
Clinical Outcomes and Ejaculatory Function in BPO Patients Treated With Silodosin
This observational study aims to evaluate the relationship between silodosin-induced anejaculation and clinical outcomes in male patients with benign prostatic obstruction (BPO).
- Conditions
- Benign Prostate Obstruction (BPO), Lower Urinary Tract Symptom, Ejaculatory Dysfunction, Anejaculation
- Trial name
- NCT06989515
- Volunteers
- 100 people
- Sponsor
- Marmara University
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Ultrasound IPP to Predict Response to Medical Therapy in LUTS/BPH
This prospective cohort study evaluated whether transabdominal ultrasound measurement of intravesical prostatic protrusion predicts symptom severity and response to medical therapy in men aged 50 years or older with lower urinary…
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms, Bladder Outlet Obstruction
- Trial name
- NCT07306767
- Testing
- Transabdominal ultrasound measurement of intravesical prostatic protrusion, Alpha-adrenergic blocker, 5-alpha reductase inhibitor
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University
BPH With Urinary Obstruction, Prostatic Hyperplasia
Low Power HOLEP Versus TURP
Patients with obstructed flow due to BPH will be enrolled into 2 groups, group will undergo TURP and the other group will undergo Low power HOLEP
- Trial name
- HOLEP vs TURP (NCT07741214)
- Testing
- low power HOLEP, TURP
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection, Benign Prostatic Hyperplasia With Outflow Obstruction
Bipolar Resection vs Enucleation of Prostate
The aim of this study is to evaluate efficacy and safety of transurethral resection of the prostate and bipolar enucleation of the prostate.
- Conditions
- Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection, Benign Prostatic Hyperplasia With Outflow Obstruction, Benign Prostatic Hyperplasia With Symptomatic Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
- Trial name
- TURP vs BiTUEP (NCT06983444)
- Testing
- TURP, TUEP
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- South Valley University
Prostate Cancer, Pain Management
Effect of Rectus Block Timing on Opioid Use
The aim of this study is to observe the effect of administering local anesthetic to the abdominal wall at the beginning or end of surgery under general anesthesia on opioid consumption during surgery.
- Conditions
- Prostate Cancer, Pain Management, Nociception Level Index(NoL), Nociception Monitoring
- Trial name
- PROSTIMERSBOP (NCT07433140)
- Testing
- Early bilateral rectus sheat block, Late bilateral rectus sheat block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Koc University Hospital
Benign Prostate Hypertrophy(BPH)
Transurethral Focal Laser Ablation Versus Transurethral Prostatectomy For Management Of Benign Prostatic Obstruction
Introduction and objectives: Laser prostatectomy has become an increasingly popular and effective alternative to transurethral resection of the prostate (TURP) for the treatment of benign prostatic hyperplasia (BPH).-.
- Trial name
- NCT07196475
- Testing
- FOCAL LASER ABLATION OF PROSTATE
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Urinary Retention, Benign Prostate Obstruction (BPO)
Effect of Catheter Duration on Prostate Laser Enucleation Surgery Outcomes in Patients With Urinary Retention
Benign Prostatic Obstruction (BPO) is a common condition in aging men that can lead to urinary retention, often requiring the use of an indwelling urinary catheter.
- Trial name
- NCT07603011
- Testing
- Laser Enucleation of the Prostate (HoLEP, ThuLEP, ThuFLEP)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Eskişehir Osmangazi University Medicine Faculty Hospital
BPH With Urinary Obstruction, Male
HoLEP vs BPRP of a Large Volume BPH: a Randomised Controlled Trial
To compare bipolar resection versus holmium laser enucleation for management of large BPH.
- Trial name
- NCT04143399
- Testing
- holmium laser enucleation of the prostate, Bipolar resection of the prostate
- Where
- Egypt
- Volunteers
- 145 people
- Sponsor
- Cairo University
Benign Prostatic Hyperplasia (BPH)
Prostatic Artery Embolization (PAE) for Treatment of Signs and Symptoms of Benign Prostatic Hyperplasia (BPH) Using Bead Block Microspheres
This is an open-labeled, non-randomized feasibility study to evaluate the safety of prostate artery embolization (PAE) for the treatment of lower urinary tract symptoms attributed to benign prostatic hyperplasia (BPH).
- Trial name
- NCT03052049
- Testing
- Prostate Artery Embolization
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Northwestern University
Prostate Cancer, Bladder Outlet Obstruction
Prostatic Artery Embolization in Advanced Prostate Cancer
This is a pilot study assessing efficacy and safety in patients with advanced prostate cancer.
- Trial name
- NCT03457805
- Testing
- Prostatic Artery Embolization
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Dominik Abt
Urinary Bladder, Overactive, Prostatic Hyperplasia, Benign
Comparison of Concurrent Endoscopic Prostate Surgery With Botox-A Injection and Postoperative Medical Therapy in BPH Patients With Overactive Bladder Symptoms
Intravesical OnabotulinumtoxinA (BoNT-A) injection performed concurrently with endoscopic prostate surgery provides superior clinical improvement at the 12th postoperative week compared to standard medical therapy in patients…
- Conditions
- Urinary Bladder, Overactive, Prostatic Hyperplasia, Benign, Bladder Outlet Obstruction, Botulinium Toxin-A
- Trial name
- BOPROST (NCT07554989)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Prostate Cancer (Diagnosis), Prostate Biopsy
TENS During Transperineal Prostate Biopsy
Transperineal prostate biopsy is a safe and effective method of diagnosing prostate cancer. When performed under local anaesthesia in an outpatient setting, it can cause significant pain, particularly during the periprostatic…
- Conditions
- Prostate Cancer (Diagnosis), Prostate Biopsy, Pain, Procedural
- Trial name
- TENS 2 (NCT07578324)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Medical University of Gdansk