Clinical trials: Prostatic Biopsy
Prostate Cancer (Adenocarcinoma), Prostate Biopsy
RegisterPROS - A Registry for Prostate Cancers
Prostate cancers are derived from epithelial cells in the prostate gland. Treatment options include surgery, medical (androgen signaling targeted and chemotherapy) and radiation therapy including radioligand therapy (RLT).
- Conditions
- Prostate Cancer (Adenocarcinoma), Prostate Biopsy, Prostatectomy, Radioligand
- Trial name
- RegisterPROS (NCT06872619)
- Testing
- PROSTest
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Wren Laboratories LLC
Prostate Cancer
Evaluation of the SENSEI® Laparoscopic Tethered Gamma Probe for 99mTc-nanocolloid Sentinel Lymph Node Biopsy in Prostate Cancer
This study is a prospective, open label, single-arm study to examine the performance and safety of the SENSEI® laparoscopic tethered gamma probe in patients undergoing 99mTc-nanocolloid SLNB for prostate cancer (PCa) during RP…
- Trial name
- LPM-012 (NCT04632251)
- Testing
- SENSEI®
- Where
- 4 sites in Belgium, France and 2 more
- Volunteers
- 56 people
- Sponsor
- Lightpoint Medical Limited
Prostate Cancer
ClariCore System Used in Transperineal Prostate Biopsy
The overall objective of this study is to acquire ultrasound images, spectral data and prostate tissue biopsy cores using the ClariCore System via a transperineal approach.
- Trial name
- NCT03734575
- Testing
- ClariCore System
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Precision Biopsy, Inc.
Prostate Cancer
Prospective Prolaris Value and Efficacy
This is a prospective study to measure the impact on first-line therapy of genomic testing of biopsy tissue from recently diagnosed treatment-naïve patients with early stage localized prostate cancer.
- Trial name
- P-PROVE (NCT03152448)
- Testing
- Prolaris
- Where
- 12 sites in United States
- Volunteers
- 1,511 people
- Sponsor
- Myriad Genetic Laboratories, Inc.
Prostate Cancer
SonoVue Guided Prostate Biopsy
This is a phase III European multicenter, open label, prospective study to assess the diagnostic accuracy of the use of SonoVue contrast agent to guide prostate biopsies in comparison with the current practice of ultrasound…
- Trial name
- NCT00911027
- Testing
- Contrast-enhanced ultrasound guided biopsy, ultrasound guided systematic biopsy
- Where
- 17 sites in Austria, Belgium and 5 more
- Volunteers
- 282 people
- Sponsor
- Bracco Diagnostics, Inc
Prostate Cancer
Urology San Antonio MRI/MicroUS Comparison
This study compares micro-ultrasound image targeted prostate biopsy with multi-parametric MRI targeted biopsy in men indicated for prostate biopsy due to suspicion of prostate cancer.
- Trial name
- NCT03762616
- Testing
- Micro-ultrasound targeted biopsy, mpMRI targeted biopsy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Exact Imaging
Locally Advanced Prostate Cancer
Combination Casodex® and Iressa™ in Locally Advanced Prostate Cancer
The purpose of this study is to determine if the addition of ZD1839 Iressa™ to standard treatment with Casodex® (bicalutamide) for locally advanced prostate cancer can detect a difference in the rate of decrease of prostate…
- Trial name
- NCT00319787
- Testing
- Iressa
- Where
- 3 sites in Norway
- Volunteers
- 102 people
- Sponsor
- AstraZeneca
Cellular Diagnosis, Prostate Cancer
ClariCore System Used in Transrectal Ultrasound Guided Prostate Biopsy for Real-Time Tissue Evaluation
The purpose of this study is to demonstrate the effectiveness and safety of the ClariCore System in obtaining prostate biopsies with device feedback that provides real-time tissue classification.
- Trial name
- SCORE (NCT03504761)
- Testing
- ClariCore Optical Biopsy System
- Where
- 6 sites in United States
- Volunteers
- 325 people
- Sponsor
- Precision Biopsy, Inc.
Benign Prostatic Hyperplasia, Prostate Cancer
Effects On Dihydrotestosterone Regulated Gene Expression In Benign Prostatic Hyperplasia Or Prostate Cancer
Dutasteride is used in the treatment of benign prostate enlargement (BPH).It inhibits conversion of testosterone (T) into the more potent dihydrotestosterone (DHT) to stop prostate (and possibly prostate cancer) growth.
- Trial name
- NCT00375765
- Testing
- Dutasteride
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- GlaxoSmithKline
Bacterial Infections
BAYQ3939, 1000 mg Tablet in Transrectal Needle Biopsies of the Prostate (TRNBP) - Infection Prophylaxis
The primary purpose of this clinical trial is to compare in a double-blind randomized trial, the efficacy and safety of ciprofloxacin MR 1000 mg tablets given as a single-dose or as a multiple-dose regimen for the prevention of…
- Trial name
- NCT00670215
- Testing
- Ciprofloxacin single dose, Ciprofloxacin triple dose
- Where
- 51 sites in United States, Brazil and 4 more
- Volunteers
- 497 people
- Sponsor
- Bayer
Prostate Cancer
Measurements Of Zinc Concentration On Specimens Taken During Trans-Perineal Prostate Biopsy
The purposes of this study are to: i) confirm and improve the accuracy of the correlation between levels of Zinc in prostate tissue and the grade of prostate cancer in that tissue as determined through pathology; and ii)…
- Trial name
- NCT01915316
- Testing
- prostate biopsy
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- ProSight
Prostate Cancer
Telomere Associated Variables (TAVs) in Prostate Cancer
This research project results from the interest in continuing the collaboration with the previous LL-HURS-ONC001 clinical validation study, which gives cause to the present study.
- Trial name
- NCT04124900
- Where
- 10 sites in United States, Spain
- Volunteers
- 509 people
- Sponsor
- Life Length SL
Prostate Cancer
Semi-automatic Download of Prostate Biopsy Cores While Keeping the Orientation, Unfolding and Unity of the Sample
Performance evaluation of a novel, semi-automated device and method for needle core biopsy download compared to standard methods in terms of: 1. Biopsy core length obtained (i.e. collecting all tissue fragments) 2.
- Trial name
- NCT01692405
- Testing
- NaviGo Bx™, biopsy sponge pad
- Where
- Israel
- Volunteers
- 436 people
- Sponsor
- UC Care, Ltd.
Brest Cancer, Lung Cancer (NSCLC)
The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and Immune Cell Transcriptomic Profiling
The purpose of the CCANED-CIPHER study is to develop and validate an AI-based blood test for early cancer detection and to monitor treatment effectiveness in cancer patients.
- Conditions
- Brest Cancer, Lung Cancer (NSCLC), Pancreatic Cancer, Adult, Prostate Cancers
- Trial name
- CCANED-CIPHER (NCT06717295)
- Testing
- DiNanoQ: A multi-cancer early detection (MCED) blood test, DiNanoTrack: Therapeutic Response Monitoring Blood Test
- Where
- 4 sites in Argentina, Nigeria and 1 more
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Javier Toledo
Prostate Cancer
PRostate Cancer Individual Signature Evaluation Trial in Patients Undergoing Scheduled Prostate Biopsy
The purpose of this study is to develop and validate a blood-based diagnostic test that will predict prostate biopsy outcome as positive or negative for prostate cancer.
- Trial name
- PReCISE (NCT00966095)
- Where
- 17 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- Source MDx
Prostate Cancer
Assessment of VMCore Biopsy Versus Standard of Care Biopsy
Prostate biopsy is the definitive test to establish the diagnosis of prostate cancer. The standard of care biopsy needles do not predictably obtain full cores of tissue and what tissue obtained is often fragmented, making…
- Trial name
- NCT04982536
- Testing
- VMCore Biopsy System, Standard of Care Biopsy Needle
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Uro-1 Medical
Prostate Cancer
Prostate Guided Biopsy Study Evaluating the Diagnostic Performance of Prostate HistoScanning
The primary objective of the PHSTT-01 trial is to determine if prostate HistoScanning (HS) analysis can be used to improve the detection of clinically significant prostate cancer (PCa), and potentially reduce the burden and…
- Trial name
- PHSTT-01 (NCT01950871)
- Testing
- Prostate HistoScanning
- Where
- 34 sites in Austria, Belgium and 16 more
- Volunteers
- 80 people
- Sponsor
- Advanced Medical Diagnostics s.a.
Indication for Prostate Biopsy Due to Suspected Prostate Cancer
PRospective Prostate biOmarker Study
Correlation of a glycoprotein panel with prostate biopsy outcome and PCa aggressiveness
- Trial name
- PROPOSe (NCT03565289)
- Testing
- Blood sample collection
- Where
- 11 sites in Austria, Denmark and 1 more
- Volunteers
- 455 people
- Sponsor
- ProteoMediX AG
BPH
Evaluation of SureCore Plus Biopsy System
This is a post-market study of a cleared biopsy system. The quality of tissue cores varies with standard of care biopsy needles.
- Trial name
- NCT06550960
- Testing
- Evaluation of two biopsy systems
- Volunteers
- 30 people
- Sponsor
- Uro-1 Medical
Cellular Diagnosis, Prostate Cancer
ClariCore Optical Biopsy System Used in TRUS (Trans-Rectal Ultrasound)-Guided Prostrate Biopsy
The purpose of the study is to collect information on prostrate biopsy tissue for use in developing a method determining the difference in normal and cancerous prostrate tissue using the ClariCore System.
- Trial name
- NCT02928640
- Testing
- ClariCore System
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Precision Biopsy, Inc.