Clinical trials: Prostatic Hypertrophy, Benign
Prostatic Hyperplasia
A 20-Week Study of a New Treatment for Men With Benign Prostatic Hyperplasia (BPH).
Patients who are currently symptomatic and have been diagnosed with BPH by a physician may qualify for this 20-week study. Patients must not be diabetic, must not have prostate cancer and must not have had any surgery to repair…
- Trial name
- NCT00044226
- Testing
- ML-04A
- Where
- 14 sites in United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Milkhaus Laboratory
Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptoms
Prostate Artery Embolization: Single Center Experience
Benign prostatic hyperplasia (BPH) is an enlarged prostate gland from smooth muscle and glandular hyperplasia seen in the aging population with a prevalence of upto 90% in patients in the ninth decade.
- Trial name
- NCT04766268
- Testing
- Prostate artery embolization
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Benign Prostatic Hyperplasia
Laser Enucleation of Prostate (LEP) Versus Transurethral Resection of Prostate (TURP)
Benign prostatic hyperplasia (BPH) refers to the proliferation of smooth muscle and epithelial cells of the prostate gland. The enlarged gland has the potential to result in lower urinary tract symptoms (LUTS) secondary to either…
- Trial name
- NCT03062111
- Testing
- ProTouch Laser Enucleation of Prostate (LEP), Transurethral Resection of Prostate (TURP)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Boston University
LUTS, Benign Prostatic Hyperplasia
Clinical Trial to Investigate the Pharmacokinetic Drug Interaction Between Solifenacin and Tamsulosin
The purpose of this study is to investigate the pharmacokinetic drug interaction between Solifenacin and Tamsulosin in healthy male volunteers.
- Conditions
- LUTS, Benign Prostatic Hyperplasia, Overactive Bladder
- Trial name
- NCT02180997
- Testing
- Tamsulosin, Solifenacin, Tamsulosin and solifenacin
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
Benign Prostatic Hyperplasia, Urinary Obstruction
Treatment of BPH With CO2 Serenoa +PEA as Monotherapy or in Combination With Tamsulosin: ProSeRePEA Trial
The objective of this study is to evaluate the efficacy of the supplement PEAPROSTIL 600 (FARMITALIA®) composed of Serenoa Repens combined with PEA in single or combined therapy with alpha-blocker in the reduction of voiding…
- Conditions
- Benign Prostatic Hyperplasia, Urinary Obstruction, Lower Urinary Tract Symptoms
- Trial name
- ProSeRePEA (NCT06181175)
- Testing
- PEAPROSTIL 600 + Tamsulosin 0.4 mg, Tamsulosin 0.4 mg, PEAPROSTIL 600 mg
- Where
- Italy
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Benign Prostatic Hyperplasia, Enlarged Prostate With Lower Urinary Tract Symptoms
Emsella for Reducing tSUI After HOLEP
This study aims to investigate the effectiveness of the Emsella chair treatments at different timepoints. Before and after the holmium laser enucleation of the prostate (HoLEP).
- Conditions
- Benign Prostatic Hyperplasia, Enlarged Prostate With Lower Urinary Tract Symptoms, Enlarged Prostate (BPH)
- Trial name
- NCT07580404
- Testing
- Emsella chair
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Benign Prostate Hypertrophy(BPH)
Investigating the Adjunctive Use of Mirabegron in the Early Post-Rezum Procedure Period
The investigators propose conducting a randomized controlled trial at the Men's Health Clinic to evaluate whether patients who start and continue mirabegron postoperatively after undergoing Rezum therapy experience enhanced…
- Trial name
- NCT07017439
- Testing
- Beta-3 agonists (Mirabegron/Myrbetriq)
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
BPH
Comparison Between Tamsulosin and Tadalafil in Management of Benign Prostatic Hyperplasia Long Term Study
Comparison between tamsulosin and Tadalafil in management of benign prostatic hyperplasia A Randomised Trial
- Trial name
- NCT05818670
- Testing
- Tamsulosin, Tadalafil
- Where
- 2 sites in Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Ejaculation Abnormal, BPH With Urinary Obstruction
Ejaculation Preserving Photoselective Vaporization Versus Plasma Kinetic Vaporization Versus Transurethral Resection Of The Prostate: A RCT
To Evaluate and compare the outcome and coast of ejaculation sparing management of BPH using 3 different techniques: PVP, PKVP and TURP. Ejaculation sparing TURP group is considered the standard control group.
- Conditions
- Ejaculation Abnormal, BPH With Urinary Obstruction, Prostatic Hyperplasia, Prostate Disease
- Trial name
- EPPROSTATECT (NCT03589196)
- Testing
- Ejaculation Preserving Photoselective Vaporization, Ejaculation Preserving Plasma Kinetic Vaporization, Ejaculation Preserving Transurethral Resection Of The Prostate
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Benign Prostate Hyperplasia
Safety and Pharmacokinetic Interaction Study of Tadalafil and Dutasteride
This is an open-label, two-arm, one-sequence, cross-over study to evaluate the safety and pharmacokinetic interaction after oral concomitant administration of tadalafil and dutasteride in healthy male volunteers.
- Trial name
- NCT01942551
- Testing
- Tadalafil, Dutasteride
- Where
- South Korea
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Dongkook Pharmaceutical Co., Ltd.
Benign Prostatic Hyperplasia
A Clinical Trial to Evaluate the Bioequivalence of AD-116A and AD-1161 Under Fed Conditions in Healthy Adult Male Volunteers
This study compares and evaluates the bioequivalence of AD-116A and AD-1161 in healthy adult male volunteers under fed conditions.
- Trial name
- NCT07722871
- Testing
- AD-116A, AD-1161
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Benign Prostatic Hyperplasia
Pharmacokinetics and Safety/Tolerability of YY-201 in Comparison to Dutasteride and Tadalafil
A randomized, open label, single dose, two-way crossover clinical trial to investigate the pharmacokinetics and safety/tolerability of YY-201 in comparison to Dutasteride and Tadalafil administered in healthy male volunteers
- Trial name
- NCT03240939
- Testing
- Dutasteride 0.5 mg, Tadalafil 5 mg, YY-201
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Yuyu Pharma, Inc.
Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection
Conventional Fluid Management Versus Plethysmography Variability Index-based Goal-directed Fluid Management in Patients Undergoing Transurethral Resection of the Prostate
Transurethral resection of the prostate (TURP) is a widely performed surgical procedure for the management of benign prostatic hyperplasia.
- Trial name
- TURP (NCT07669337)
- Testing
- Conventional Fluid Management, Plethysmography Variability Index (PVI)-Guided Goal-Directed Fluid Management
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cairo University
Enlarged Prostate (BPH), Benign Prostatic Hyperplasia
Moses 2.0 vs Magneto for HoLEP - a Randomized Controlled Trial
The objective of this study is to compare the Magneto 150 holmium laser to the current MOSES 2.0 technology to see if there is a benefit in decreased hemostasis time intraoperatively.
- Trial name
- NCT07632742
- Testing
- Magneto 150 holmium laser, Moses 2.0 holmium laser
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Benign Prostatic Hyperplasia
Urolift Pre-SBRT for Reduced Urinary Toxicity in Patients With BPH and Prostate Cancer.
Many patients may face long-term urinary side effects following stereotactic body radiation therapy (SBRT), including increased urinary frequency, dysuria, and nocturia.
- Trial name
- NCT05148156
- Testing
- Urolift
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Moderate-to-severe Benign Prostatic Hyperplasia (BPH)
Bioequivalence Study of AJU-G721 and G721R in Healthy Adult Volunteers Under Fasting Conditions
To evaluate and compare the safety and pharmacokinetic profiles of "AJU-G721" (test drug) and "G721R" (reference drug) in healthy adult male subjects.
- Trial name
- NCT07643220
- Testing
- Test Drug, Reference Drug
- Where
- South Korea
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
Phase 1, Healthy
EC905 Pharmacokinetic Profile Study
A study to compare the pharmacokinetics of tamsulosin HCl and solifenacin succinate after co-administration of single entity tablets and of the combination tablet EC905 under steady state conditions at three dose strengths.
- Conditions
- Phase 1, Healthy, Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
- Trial name
- NCT02634489
- Testing
- Tamsulosin HCl, Solifenacin Succinate, EC905
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Healthy People, Benign Prostatic Hyperplasia
The Application of Multimodal Artificial Intelligence Systems in Prostate Cancer Diagnosis and Prognosis Analysis
Prostate-specific antigen (PSA) testing has limited specificity for prostate cancer diagnosis, leading to a high rate of unnecessary biopsies.
- Conditions
- Healthy People, Benign Prostatic Hyperplasia, Prostate Cancer
- Trial name
- NCT06589154
- Testing
- Multi-modal artificial intelligence model (BEAM)
- Where
- 10 sites in China
- Volunteers
- 1,651 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Benign Prostatic Hyperplasia
Evaluate the Safety and Effectiveness of Using Echogenic Embolic Agent for Embolization of Prostate Artery for Treatment of Men With BPH (PAE CEUS)
A prospective single centre study to evaluate the safety and effectiveness of using contrast enhanced ultrasound and echogenic embolic agent Ekobi Embolization Microspheres in Prostate Artery Embolization for the Treatment of Men…
- Trial name
- PAE CEUS (NCT04267445)
- Testing
- Embolization of prostatic artery under ultrasound guidance
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Benign Prostatic Hyperplasia
A Clinical Trial to Evaluate the Safety and the Pharmacokinetics of AD-116 Compared to AD-1161 in Healthy Adult Male Volunteers
The study compare and evaluate the safety and pharmacokinetic characteristics between the administration of AD-116 and the administration of AD-1161 in healthy adult male volunteers
- Trial name
- NCT07103278
- Testing
- AD-116, AD-1161
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.