Clinical trials: Prostatic Hypertrophy, Benign
Benign Prostatic Hyperplasia (BPH)
Post-Market Study to Assess iTind Safety in Comparison to UroLift
The study objective is to evaluate the efficacy and safety of the iTind device compared to UroLift.
- Trial name
- MT-08 (NCT04757116)
- Testing
- iTind, UroLift
- Where
- 19 sites in United States, United Kingdom
- Volunteers
- 256 people
- Sponsor
- Olympus Corporation of the Americas
Benign Prostatic Hyperplasia With Symptomatic Lower Urinary Tract Symptoms
Anesthesia Type and HoLEP Outcomes: A Multi-Center Study
1. What is this study about, and why is it required? The goal of this observational study is to learn if anesthesia type (e.g., general anesthesia, spinal anesthesia) affects the safety and efficiency of HoLEP surgery.
- Trial name
- NCT07585552
- Where
- Turkey (Türkiye)
- Volunteers
- 320 people
- Sponsor
- Ondokuz Mayıs University
Cardiovascular Disease, Diabetes
Robust Evaluation to Measure Improvements in Nonadherence From Low-cost Devices
The aim of this study is to determine whether adherence to oral maintenance medications differs for patients randomized to receive a RxTimerCap, a Take-N-Slide, a standard pillbox, or none of these devices, with the hypothesis…
- Conditions
- Cardiovascular Disease, Diabetes, Breast Cancer, Depression
- Trial name
- REMIND (NCT02015806)
- Testing
- RxTimerCap, Take-N-Slide, Pillbox
- Where
- United States
- Volunteers
- 53,480 people
- Sponsor
- Brigham and Women's Hospital
Prostatic Hyperplasia
Efficacy, Tolerability and Safety of ALNA® in Patients With Benign Prostatic Syndrome (BPS)
Study to assess efficacy, tolerability and safety parameters of a one month ALNA® - treatment after switch from Terazosin-treatment
- Trial name
- NCT02244333
- Testing
- ALNA®
- Volunteers
- 4,575 people
- Sponsor
- Boehringer Ingelheim
Prostatic Hyperplasia, Adrenergic Alpha-Antagonists
The Effectiveness of Saw Palmetto and Sanmiaoshan on Benign Prostatic Hyperplasia in Chinese Patients
The purpose of this study is to assess the effect of saw palmetto and sanmiaoshan, on top of alpha blocker, on urinary flow rate and BPH symptoms in patients with BPH.
- Trial name
- NCT00497939
- Testing
- Saw palmetto and sanmiaoshan capsule
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Hospital Authority, Hong Kong
Benign Prostatic Hyperplasia
A Study in Men With Benign Prostatic Hyperplasia
The purpose of the study is to determine whether LY500307 helps symptoms of Benign Prostatic Hyperplasia (BPH)
- Trial name
- NCT01097707
- Testing
- LY500307
- Where
- 70 sites in United States, Australia and 6 more
- Volunteers
- 414 people
- Sponsor
- Eli Lilly and Company
BPH/LUTS/Sexual Functions
Multicenter Prospective Study on the Changes of Sexual Function Following Treatment With Alfuzosin (Xatral XL®) in Patients With Benign Prostate Hypertrophy
To collect under daily practice conditions, clinical data on the changes of sexual function when a new formulation of alfuzosin(Xatral XL® )is administered once daily in patients with lower urinary tract symptoms(LUTS) suggestive…
- Trial name
- NCT00542165
- Testing
- Alfuzosin
- Where
- South Korea
- Volunteers
- 166 people
- Sponsor
- Sanofi
Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Bipolar Plasmakinetic TURP Vs Monopolar TURP in the Treatment of Lower Urinary Tract Symptoms
Randomized controlled trial with one-year follow-up comparing intra, peri and postoperative outcomes for plasmakinetic transurethral resection of prostate (PK-TURP) and monopolar transurethral resection of prostate (M-TURP) in…
- Conditions
- Prostatic Hyperplasia, Lower Urinary Tract Symptoms, Transurethral Resection of Prostate
- Trial name
- NCT03936244
- Testing
- Transurethral Resection of the Prostate (TURP)
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario de Fuenlabrada
Prostate Cancer
Feasibility and Toxicity of Degarelix for Prostate Downsizing Prior to Permanent Seed Prostate Brachytherapy
This study will investigate the efficacy of Degarelix, a Luteinizing Hormone Releasing Hormone (LHRH) antagonist, to reduce prostate volume prior to permanent seed prostate brachytherapy.
- Trial name
- NCT01446991
- Testing
- Degarelix
- Where
- 3 sites in Canada
- Volunteers
- 50 people
- Sponsor
- British Columbia Cancer Agency
Treatment of Benign Prostatic Hyperplasia
Ablation Efficacy of Contact Side Firing Fiber in Predefined Settings for Treating BPH
Twenty (20) subjects presenting with a hyperplasia enlarged prostate and candidates for surgery will undergo a single treatment for ablation of the prostate using the study device.
- Trial name
- NCT02683980
- Testing
- Lumenis Pulse P120H and Xpeeda side firing fiber
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Boston Scientific Corporation
BPH With Urinary Obstruction
Early Versus Late Catheter Removal in Patients With Acute Urinary Retention Secondary to BPH Under Tamsulosin Treatment
The aim of this work is to compare between early (3days) and late(7days) removal of urinary catheter after acute urine retention in patients with Benign Prostatic Hyperplasia under Tamsulosin treatment.
- Trial name
- NCT03280420
- Testing
- Early catheter removal, Late catheter removal
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Salem Hassan Salem Mohamed
Benign Prostatic Hyperplasia
Pharmacovigilance Study To Evaluate Safety Of AVODART In Subjects With Benign Prostate Hyperplasia
This study has 4 phases: screening phase (visit 1), treatment phase (visit 2 - 6 mths after treatment initiation), and end of treatment phase (visit 3 - end of year 1).
- Trial name
- NCT00593593
- Volunteers
- 1,000 people
- Sponsor
- GlaxoSmithKline
Prostatic Hyperplasia
A-botulinic Toxin for Symptomatic Benign Prostate Hypertrophy
BPH is very common in elderly men, it is a stromal as well as epithelial invasion of the prostatic gland. Due to an imbalance between growth and apoptosis cellular mechanisms that are not fully elucidated.
- Trial name
- PROTOX (NCT01275521)
- Testing
- BONT-A intra-prostatic injection, Optimized medical BPH treatment
- Where
- 11 sites in France
- Volunteers
- 127 people
- Sponsor
- University Hospital, Bordeaux
Avascular Necrosis of the Femoral Head, Coronary Artery Disease (CAD)
Desflurane Potentially Induces Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Perioperative Procedures by Modulating Cdc42 and Clock Proteins
This clinical trial investigates whether desflurane induces postoperative cognitive dysfunction (POCD) in elderly patients undergoing perioperative procedures by modulating Cdc42 and Clock proteins.
- Conditions
- Avascular Necrosis of the Femoral Head, Coronary Artery Disease (CAD), Benign Prostatic Hyperplasia (BPH), Cholecystitis
- Trial name
- NCT06772558
- Testing
- Desflurane Inhalation, mechanical ventilation (MV)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xiaguang Duan
Benign Prostatic Hyperplasia
Effect of Dutasteride on Bladder Wall Hypertrophy in Patients With Benign Prostatic Obstruction
Increased bladder mass occurs as a consequence of bladder outlet obstruction in animals and patients, and relief of bladder outlet obstruction reverses an increased bladder mass.
- Trial name
- NCT00827814
- Testing
- Dutasteride
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Samsung Medical Center
Nonmalignant Neoplasm, Prostate Cancer
Pelvic Floor Muscle Training and Biofeedback or Standard Therapy in Men Who Have Undergone Radical Prostatectomy or Transurethral Resection of the Prostate
RATIONALE: Personalized training by a health professional may improve urinary incontinence. It is not yet known whether pelvic floor muscle training and biofeedback are more effective than standard therapy in improving urinary…
- Conditions
- Nonmalignant Neoplasm, Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment, Sexual Dysfunction
- Trial name
- NCT00632138
- Testing
- exercise intervention, questionnaire administration, biofeedback
- Where
- 37 sites in United Kingdom
- Volunteers
- 800 people
- Sponsor
- Aberdeen Royal Infirmary
Prostatic Hyperplasia
Benefits of Adherence to 5-alpha Reductase Inhibitor Treatment in Men With Enlarged Prostate: An Assessment of Medicare and Medicaid Patients Using the MarketScan Database
Adherence and length of treatment with a 5-alpha reductase inhibitor (5ARI) therapy may be associated with improved clinical outcomes for patients with enlarged prostates (EP) and lower health care related costs.
- Trial name
- NCT01376258
- Testing
- 5ARI
- Volunteers
- 28,903 people
- Sponsor
- GlaxoSmithKline
Benign Prostatic Hyperplasia (BPH), Overactive Bladder
A Study to Evaluate Drug-drug Interactions Between BR9006-1 and BR9006-2 in Healthy Male Volunteers.
To evaluate the influence of BR9006-1 and BR9006-2 on pharmacokinetics, safety, and tolerability when administered separately or co-administered to healthy male volunteers.
- Trial name
- NCT04485585
- Testing
- BR9006-1, BR9006-2
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd