Clinical trials: Prostatic Intraepithelial Neoplasia
Cancer Risk, Cancer Predisposition Syndrome
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
This research study is creating a way to collect and store specimens and information from participants who may be at an increased risk of developing cancer, or has been diagnosed with an early phase of a cancer or a family member…
- Conditions
- Cancer Risk, Cancer Predisposition Syndrome, Hereditary Cancer Prediction, Childhood Cancer Survivors
- Trial name
- NCT05463796
- Testing
- Samples
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Prostate Cancer, Prostatic Intraepithelial Neoplasia
Finasteride and Flutamide in Pre-surgical Trial in Prostate Cancer.
Pre-surgical, window-of-opportunity trials provide a suitable model to assess the activity of preventive interventions in a cost-effective manner using tissue biomarkers as surrogate endpoints.
- Trial name
- 2F (NCT06601205)
- Testing
- Flutamide, Finasteride
- Where
- Italy
- Volunteers
- 125 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Preneoplastic Conditions, Prostatic Intraepithelial Neoplasia
Prostate Cancer Prevention Study for Men With High Grade PIN (Prostatic Intraepithelial Neoplasia)
The purpose of this study is to determine if toremifene citrate is effective and safe in the prevention of prostate cancer in men who have been diagnosed with high grade prostatic intraepithelial neoplasia (PIN).
- Trial name
- NCT00106691
- Testing
- Toremifene 20 mg
- Where
- 138 sites in United States, Argentina and 1 more
- Volunteers
- 1,589 people
- Sponsor
- GTx
Intraepithelial Prostatic Neoplasia, Prostatic Neoplasms
The Effects of Lycopene on High Risk Prostatic Tissue
The purpose of this research study is to compare the effects of a lycopene supplement made from tomatoes to a placebo (a capsule with no active ingredients) in men who have abnormal cells in the prostate, but have not yet had…
- Trial name
- NCT01443026
- Testing
- Lycopene 30mg
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- University of Illinois at Chicago
Prostatic Intraepithelial Neoplasia
A Pilot Study of Lycopene Supplementation in Prostatic Intraepithelial Neoplasia
The purpose of this study is to determine whether dietary lycopene supplementation lowers serum prostate specific antigen(PSA) in men with high grade intraepithelial neoplasia (HGPIN).
- Trial name
- NCT00178113
- Testing
- - Lyc-O-Mato (dietary supplement, 30 mg lycopene/day), - Certagen (multivitamins with minerals)
- Where
- Trinidad and Tobago
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Alveolar Bone Grafting, Bone Augmentation
Bone Augmentation Using Particulated Biomaterial and Autogenous Bone, Stabilized by Collagen Membrane and Pins (PaMP)
Twenty four patients with bone resorption on the anterior maxilla will be divided into two groups with different kinds of grafting: bone block associated with particulated biomaterial and particulated mixture of autogenous bone…
- Trial name
- PaMP (NCT02406924)
- Testing
- Biopsy, Computerized Tomography, Standardized periapical radiographs
- Volunteers
- 24 people
- Sponsor
- Pedro Tortamano
Prostatic Intraepithelial Neoplasia
A Chemoprevention Study of an Investigational Drug in Men With High Grade Prostate Intraepithelial Neoplasia (PIN)
If you are a male 30 years of age or older and have a positive diagnosis of high grade (II or III) prostate Intraepithelial Neoplasia (PIN) or have had an abnormal/suspicious prostate biopsy, you may be eligible for this study.
- Trial name
- NCT00028353
- Testing
- GTX-006 (Acapodene)
- Where
- 25 sites in United States
- Volunteers
- 500 people
- Sponsor
- GTx
Prostatic Intraepithelial Neoplasia
Broccoli, Peas and PIN
This is a parallel human intervention trial to determine to what extent a dietary intervention of broccoli or peas can change the expression (switching on or off) of genes in prostate tissue in men diagnosed with high-grade…
- Trial name
- NCT00535977
- Testing
- Broccoli, Peas
- Volunteers
- 22 people
- Sponsor
- Quadram Institute Bioscience
Prostate Cancer, Benign Prostatic Hyperplasia
Annexin A3 (ANXA3) as Protein-Based Marker for Non-Invasive Molecular Diagnostics of Prostate Carcinoma
Emerging from a differential proteomic study of sample pairs of prostate cancer and benign tissue, annexin A3 (ANXA3) was chosen as a potential novel biomarker for the early and non-invasive diagnosis of prostate cancer.
- Conditions
- Prostate Cancer, Benign Prostatic Hyperplasia, Prostatic Intraepithelial Neoplasia
- Trial name
- NCT00400894
- Volunteers
- 750 people
- Sponsor
- ProteoSys AG