Clinical trials: Prostheses
Knee Osteoarthritis
Clinical Trials of Prosthesis and Surgery Guide System
1. The subject continues the research of Professor JiaKuo Yu's research group on the personalized design, processing and manufacturing of personalized total knee replacement artificial joint prostheses and the verification of…
- Trial name
- NCT04950348
- Testing
- Personalized TKA prosthesis, Zimmer NexGen prostheses
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Prosthesis Durability
Swallowing Threshold and Efficiency for Maxillary Implant Assisted Overdenture
This study aimed to compare the swallowing threshold and efficiency of conventional maxillary implant overdenture and palatless designs.
- Trial name
- NCT06622837
- Testing
- implant overdenture
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Implant Failed, Dental Prosthesis Failure
Peri-implant Tissues in BLX® Implants
This is a randomized triple-blind clinical trial to evaluate the behavior of peri-implant tissues (bone and soft tissues) in BLX implants loaded early or delayed and with different surgical milling protocols.
- Trial name
- BLX (NCT03720236)
- Testing
- Implant bed preparation protocol, Implant loading
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Dental Prosthesis Complication
Functional Relining Versus Digital Altered Cast Using Digitally Fabricated Distal Extension Frameworks
This clinical study will be done to compare between functional relining and digital altered cast of selective pressure impression techniques for constructing mandibular distal extension removable partial dentures using digitally…
- Trial name
- NCT06082609
- Testing
- Removable partial denture
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Survival, Prosthesis
Osteopontin in Metastatic Breast Cancer Patients
OPN plays an important role in various aspects of malignancy, particularly those involved in tissue invasion and metastasis, and OPN levels have been associated with aggressive¬ness in several cancer types, including breast…
- Trial name
- NCT04274504
- Testing
- Osteopontin
- Where
- Egypt
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Failure of Dental Prosthesis
Comparison of Two Implant Prosthetic Pathways
To assess and compare the esthetic outcome and clinical performance of anterior maxillary all ceramic implant single crowns based either on prefabricated zirconia abutment veneered with pressed ceramics or on a CAD/CAM…
- Trial name
- NCT02905838
- Testing
- Anatomic e.max Abutment, CAD/CAM CARES Abutment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bern
Below Elbow Amputation
Enhancing Upper Limb Prostheses With Radio Frequency Identification
The purpose of this study is to determine if Radio Frequency Identification (RFID) can lead to greater prosthesis function and control.
- Trial name
- RFIDIBT (NCT01967004)
- Testing
- Morph
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Infinite Biomedical Technologies
Prosthesis Durability
Accuracy of Conventional and Digital Impression Techniques Used for Maxillary Hybrid Prosthesis
evaluation and comparison of the accuracy of conventional and digital impression for full arch screw retained prosthesis for edentulous maxilla.
- Trial name
- NCT05321589
- Testing
- impression techniques for implant used for maxillary screw retained hybrid prosthesis
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Mouth, Edentulous
Augmented Reality for Tooth Selection Augmented Reality for Tooth Selection
A questionnaire based study to investigate the effectiveness of an Augmented Reality App in the selection of teeth for dentures.
- Trial name
- ToothPICK (NCT03738189)
- Testing
- Augmented Reality Video
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Prostheses and Implants
Advanced Prosthetic Devices for Lower Limb Amputees
Lower limb amputation is an emerging global health concern. Currently, there are over 1.6 million amputees in the U.S. and around 6000 new amputations are recorded per annum in the UK.
- Trial name
- NCT04197011
- Testing
- prosthetic device
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Anophthalmos, Unilateral, Prosthesis User
Subjective Perception of Ocular Prosthesis Wear
The loss of an eye, whether congenital or acquired, is a severe psychological trauma with negative impact on the quality of life of the patient.
- Trial name
- NCT04321382
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Edentulous Mouth, Quality of Life
Impact of Retro-molar Pad Demarcation on Complete Denture Wearers' Satisfaction
the retromolar pad is a critical anatomical landmark in the lower edentulous arch marking the posterior end of any removable prosthesis.
- Conditions
- Edentulous Mouth, Quality of Life, Patient Satisfaction, Complete Edentulism
- Trial name
- RMP (NCT07246343)
- Testing
- carving of retromolar pad area (RMP), no carving of the retromolar pad area (RMP)
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samiha Sartawi
Partial Edentulism Class II, Dental Implants
Porcelain-fused-to-metal Versus Zirconia Implant- Supported in Mandibular Kennedy Class II
The goal of this randomized clinical trial is to compare biting force and patient satisfaction in three groups. Patients in the control group number one will receive a CoCr removable partial denture, and in the other two groups…
- Conditions
- Partial Edentulism Class II, Dental Implants, Implant
- Trial name
- NCT06150768
- Testing
- Cobalt Chromium Removable Partial Denture, Implant-Supported Porcelain-Fused-to-Metal-Fixed Partial Denture, Implant-Supported Zirconia Fixed Partial Denture.
- Where
- Egypt
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Maxillofacial Prosthesis User
Patient Satisfaction for Digital Versus Conventional Maxillary Obturator
Evidence regarding the performance of digital obturators totally fabricated using 3D printing is insufficient. This prospective randomized crossover study aimed to evaluate patient satisfaction with conventional maxillary…
- Trial name
- NCT05920811
- Testing
- conventional obturator, 3 d printed obturator
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tanta University
Peri-Implant Diseases
Salivary Biomarkers in Different Implant-Supported Prostheses
This observational cross-sectional study compared salivary biomarkers among adults with different types of implant-supported prosthetic rehabilitation and periodontally healthy adults with natural teeth.
- Trial name
- NCT07813845
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Osteoarthritis, Post-traumatic Arthritis
Postoperative Function Following Partial and Total Knee Replacement
The purpose of this study is to determine if patients with a fixed-bearing or mobile-bearing partial knee replacement perform functional activities differently than patients that have had total knee replacement or healthy…
- Trial name
- NCT00492219
- Testing
- Vanguard M fixed-bearing or Oxford mobile-bearing prostheses, Total Knee Replacement
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- New Lexington Clinic
Hemiplegia
Neural Prostheses and Gait Performance: Model-Based Strategies
The purpose of this research is to find the optimal patterns of functional electrical stimulation (FES) of muscles in the lower legs that will improve walking ability in those who have had a stroke and at the same time ensure…
- Trial name
- NCT00991406
- Testing
- FES
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Prosthesis, Amputation
Functional Outcomes of Voice Recognition Prosthesis
The purpose of this study is to evaluate the use of a voice activated prosthesis interface controller for functional outcomes as compared to standard prosthesis control.
- Conditions
- Prosthesis, Amputation, Prosthesis User
- Trial name
- NCT04595071
- Testing
- Voice Activated Prosthetic Interface (VAPI) Controller
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Amputation
Agonist-Antagonist Myoneural Interface for Functional Limb Restoration After Transtibial Amputation
This study involves the functional testing of a new lower extremity prosthesis by healthy, active participants with fully healed transtibial (below knee) amputations.
- Trial name
- NCT03913273
- Testing
- AMI transtibial amputation, Standard transtibial amputation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Degradation of Magnesium Alloy Prosthesis and New Bone Regeneration
The Clinical Study of 3D-printed Magnesium Alloy Prosthesis With Controllable Degradation Rate in the Repair of Periarticular Bone Defects
Perimarticular fracture bone defect is a common and complicated clinical disease. The current treatment for this type of injury is anatomical reduction of the fracture, where the bone defect is filled with artificial, autologous…
- Trial name
- NCT06349629
- Testing
- 3D printed WE43 magnesium alloy
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital