Clinical trials: Prosthetic
Amputation
Adaptive Recalibration of Prosthetic Leg Neural Control System
The purpose of this study is for transfemoral amputees to walk with an experimental robotic prosthesis. Electric signals will be measured from their muscles and used to help control an artificial leg.
- Trial name
- NCT02355912
- Testing
- Powered knee and ankle prosthesis
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Upper Limb Amputation Below Elbow (Injury)
Myoelectric SoftHand Pro to Improve Prosthetic Function for People With Below-elbow Amputations: A Feasibility Study
A study to investigate the hypothesis that a Pisa/IIT Robotic SoftHand Pro converted to a prosthetic terminal device will enhance the performance of people with limb loss in a wider range of daily living tasks than allowed by…
- Trial name
- SoftHand (NCT02274532)
- Testing
- SoftHand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Karen L. Andrews, M.D.
Infection in Bone
Evaluation of VSS Antibiotic Prophylaxis in Prosthetic Surgery (MRSA)
based on international guide lines, antibiotic prophylaxis in Orthoaedic major surgery has to be done with a Cephalosporin 1st generation (e.g. Cefazolin 1 g 30' before surgery).
- Trial name
- MRSA (NCT06403254)
- Testing
- There isn't an intervention name because the study is observational and has only one group.
- Where
- Italy
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants
Effect of Photodynamic Treatment on Skin Microbiome. Single Center Study
The overarching aim of this research project is to prevent orthopedic implant-associated infections. This study aims to investigate if photodynamic therapy has an effect on bacterial skin colonization and decrease number of…
- Conditions
- Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants, Surgical Site Infection, Prosthetic Joint Infection
- Trial name
- PHOMIC (NCT04067843)
- Testing
- Photodynamic treatment
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Partially Edentulous Jaw
Effect of Scanning Technology on Internal Fit of Digitally Customized Intra-radicular Attachments
This study aims to evaluate the marginal and internal fit of intra-radicular attachments fabricated by direct scanning using two different intraoral scanners compared to indirect scanning of conventional impressions.
- Trial name
- NCT07541625
- Testing
- conventional impression, Intraoral scanner
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- October 6 University
Peri-Implantitis
Lnfluence of the Prosthetic Emergence Profile on the Prevalence of Peri-implant Diseases
1. Objectives: To evaluate the influence of the shape and contour of implant-supported restorations on peri-implant soft and hard tissues by using an intraoral scanner. 2. Material and methods: 1.
- Trial name
- NCT05592314
- Testing
- No intervention
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ramón Pons Calabuig
Diagnosis Prosthetic Joint Infection
Synovial Aspiration and Serological Testing in Two-stage Revision Arthroplasty of Prosthetic Joint Infection
The two-stage protocol is gold standard in terms of infection control treating prosthetic joint infections of total hip and total knee arthroplasty.
- Trial name
- SyPJI (NCT03038464)
- Testing
- Synovial biopsy
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Amputation
Clinical Trial of Tensegrity Prosthetics K3 Promoter Foot Prosthesis
The purpose of this clinical trial is to determine if the experimental Tensegrity prosthetic foot offers a reduction of the amount of oxygen used while walking, if stability is improved over current prosthetic feet, and whether…
- Trial name
- NCT00888199
- Testing
- Experimental prosthetic foot (K3 Promoter)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tensegrity Prosthetics
Vascular Access for Hemodialysis and Inflammation
Vascular Access for Hemodialysis and Inflammation
The aim of the present study was to investigate patients free of active infection and/or thrombosis to assess if the type of vascular access (AVF, AVG, TCC), could influence: 1.
- Trial name
- NCT00850707
- Where
- Italy
- Volunteers
- 458 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Infections Joint Prosthetic
Ancef Dosage in Knee Arthroplasty : Tourniquet Clinical Trial
Tourniquet inflation during total knee arthroplasty (TKA) is commonly used to reduce bleeding in the surgical field; thereby facilitating exposure and cementation.
- Trial name
- NCT05604157
- Testing
- Use of Tourniquet
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Transtibial Amputees
Using Direct Molding Socket Technology for Trans-tibial Prosthesis in Developing Regions
The study aims to understand how well CPOs and amputees can adapt to using the Amparo socket technology. CPOs at the APDK and The Cure will be trained to use the Amparo socket technology then use it with their consenting patients…
- Trial name
- NCT04679701
- Testing
- Amparo Confidence Socket
- Where
- 2 sites in Kenya
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Amparo GmbH
Lower Limb Amputation Below Knee (Injury), Diurnal Residual Limb Fluid Volume Fluctuation
An Automatically Adjusting Prosthetic Socket for People With Transtibial Amputation
People with leg amputations often experience daily changes in the size (volume) of their residual limb. These daily changes can cause a prosthesis to fit poorly. They can also cause limb problems like pain or skin breakdown.
- Trial name
- NCT05124652
- Testing
- Auto Adjusting Prosthesis
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dental Implants, Dental Impression Materials
Splint Versus Non-splint Implant Impressions
The purpose of this study is to evaluate the effectiveness of heavy Vinyl PolySiloxane (VPS) and splinted implants impression (Study Group, SG) technique versus plaster implant impression (Control Group, CG) technique, in 12…
- Conditions
- Dental Implants, Dental Impression Materials, Dental Impression Techniques
- Trial name
- NCT01104363
- Testing
- Snow white plaster 2, Primopattern LC gel + PVS
- Where
- 2 sites in Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital San Pietro Fatebenefratelli
Defect; Internal Prosthetic Device, Implants and Grafts, Orthopedic, Bone Graft
Clinical Application of Personal Designed 3D Printing Implants in Bone Defect Restoration
Objective: Clinical application of 3D printing implant in bone defect treatment. Study design: multicenter randomized controlled study .
- Trial name
- NCT03166917
- Testing
- 3D printing implant, autogenous bone grafting
- Where
- 3 sites in China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- fang guofang
Oral Mucosa; Ulcer
Comparison of the Effects of Oral Ulceration Healing in Patients Wearing a Removable Denture
The aim of the study was comparing the effectiveness of oral mucosa healing properties of different preparations: CHX=0,2% chorhexidine digluconate, CHS=8,7% choline salicylate, CON=control group, in patients with delivered…
- Trial name
- MUCOSA HEALING (NCT06531720)
- Testing
- Chlorhexidine Gluconate, Choline Salicylate 8.7 % Oral Gel, control group
- Where
- Poland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Implant Clinical Survival, Restoration Survival
Retrospective Evaluation of Prosthetic Complications and Peri-implant Bone Resorption in Implant-supported Single Unit Fixed Restorations
This study evaluated the one-year outcomes of implant-supported single-tooth fixed restorations used to replace missing teeth. The aim was to assess the success rates of dental implants and identify potential complications during…
- Trial name
- NCT06709508
- Testing
- Examination group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Özer İşisağ
Amputation, Amputation; Traumatic, Leg, Lower
Socket Cooling Effectiveness Take Home Study
The comfort and fit of the residual limb within a prosthetic socket are of primary concern for many amputees. The residual limb is typically covered by non-breathable and non- thermally conductive materials that can create a warm…
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Amputation Stump, Limb; Absence, Congenital, Lower
- Trial name
- NCT04484805
- Testing
- ICE Condition
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Edentulous Jaw, Edentulous Alveolar Ridge
Prosthetic Complications of Screw Retained Restoration
On of the main fixed prosthetic options of completely edentulous patients is the screw-retained implant supported prosthesis which was constructed on transmucosal abutments with its encountered problems such as: hardness to make…
- Conditions
- Edentulous Jaw, Edentulous Alveolar Ridge, Edentulous Mouth
- Trial name
- NCT03674554
- Testing
- titanium bases using intra oral luting cement technique, transmucosal abutment
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthotic and Prosthetic Rehabilitation
Prosthetics-Orthotics Rehabilitation Awareness
Orthotic and prosthetic devices are essential rehabilitation tools for individuals with functional limitations resulting from amputation, musculoskeletal pathologies, neurological disorders, and congenital anomalies.
- Trial name
- NCT07734402
- Testing
- Administration of the Prosthetics and Orthotics Awareness Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Lower Limb Amputation
Evaluation of Limb Health Associated With a Prosthetic Vacuum Socket System
The purpose of the study is to evaluate residual limb circulation and skin health associated with the use of a prosthetic vacuum socket. A conventional non-vacuum prosthetic socket will be compared to a vacuum prosthetic socket.
- Trial name
- NCT01839123
- Testing
- Prosthetic Suction or Pin Socket, Prosthetic LimbLogic Vacuum Socket
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ohio Willow Wood