Clinical trials: Prosthetic
Urinary Incontinence
Adjustable Continence Therapy (ACT) Device for the Treatment of Female Stress Urinary Incontinence
The purpose of this study is to evaluate the safety and effectiveness of a minimally invasive surgical procedure in up to 160 implanted female patients in which two adjustable balloons (one on each side of the urethra) are…
- Trial name
- ACT (NCT00113555)
- Testing
- ACT (Adjustable Continence Therapy)
- Where
- 7 sites in United States, Canada
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Uromedica
Orthotic and Prosthetic Rehabilitation
Prosthetics-Orthotics Rehabilitation Awareness
Orthotic and prosthetic devices are essential rehabilitation tools for individuals with functional limitations resulting from amputation, musculoskeletal pathologies, neurological disorders, and congenital anomalies.
- Trial name
- NCT07734402
- Testing
- Administration of the Prosthetics and Orthotics Awareness Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Amputation, Amputation; Traumatic, Leg, Lower
Clinical Outcomes With Passive MPKs vs. Powered Prosthetic Knees
The goal of this proposed project is to gather community-based data from the K4-level Transfemoral Amputee (TFA) population to aid in evidence-based prescription of powered prosthetic knees (i.e., choosing the right device to…
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User
- Trial name
- NCT05267639
- Testing
- Power Knee
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Brain Diseases, Memory Disorders
Low Intensity Focused Ultrasound for Learning and Memory and Emotion Regulation
The goal of this clinical trial is to investigate the impact of low intensity focused ultrasound pulsation (LIFUP) to two different brain regions, the amygdala and entorhinal cortex, in older adults.
- Conditions
- Brain Diseases, Memory Disorders, Learning Disabilities, Cognitive Impairment
- Trial name
- LIFUPMEMEMOT (NCT03717922)
- Testing
- Low Intensity Focused Ultrasound Pulsation to Amygdala, Low Intensity Focused Ultrasound Pulsation to Entorhinal Cortex
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Staphylococcal Infections, Joint Prosthesis
StaphVAX Immunogenicity in Orthopedic Implant Patients
S. aureus is the most common pathogen involved in prosthetic joint infection. StaphVAX® is a vaccine to prevent these infections, which conjugates the purified capsular polysaccharides of S. aureus to a carrier protein.
- Trial name
- NCT00211926
- Testing
- S. aureus Type 5 & 8 Capsular Polysaccharide Conjugate
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nabi Biopharmaceuticals
Bone Loss
Prosthetic Modality and MBL
The present study will test the effect of different prosthetic modalities on conical and internal hex connection implants, assessing the radiographic MBL changes after one year.
- Trial name
- NCT07156110
- Testing
- Traditional prosthetic procedure, one abutment-one time
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Studio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo
Nutrition Disorders, Edentulous Jaw
Effect of Prosthetic Rehabilitation on Nutritional Status of Geriatric Patients
This study examines the effects of prosthetic treatment options applied to edentulous geriatric individuals who applied to Marmara University Faculty of Dentistry on chewing function, food consumption status, malnutrition status…
- Trial name
- NCT05777980
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Marmara University
Prosthesis (Internal) Complications
Comparison of Prosthetic Complications and Framework Misfit Among Different Cobalt-Chromium Framework Fabrication Techniques
This randomized clinical study aimed to compare prosthetic complications and framework misfit associated with three different fabrication techniques of cobalt-chromium frameworks-conventional casting, CAD/CAM milling, and…
- Trial name
- NCT07489027
- Testing
- Implant supported prosthesis
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Edentulism
Patient Satisfaction and Prosthetic Complications of Bar Locator Versus Bar Clip Attachments for Mandibular Two-Implant Overdentures
Purpose: This study evaluated patient satisfaction and oral health-related- quality of life (OHRQoL) with implant overdentures retained with bar locator versus bar clip attachment for mandibular two-implant overdentures.
- Trial name
- NCT06673186
- Testing
- overdenture
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Lower Limb Amputation, Older Adults
Study of WiiFit to Enhance Walking in Older Adult Amputees
WiiNWALK is a 4 week physical activity, with the intervention of a WiiFit, targeted to improve walking capacity in individuals with either a unilateral below-knee or above-knee amputation.
- Trial name
- WiiNWalk (NCT01942798)
- Testing
- Nintendo Wii, Wii Big Brain Academy Degree program
- Where
- 5 sites in Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Prosthetic Joint Infection
Rapid Diagnosis of Prosthetic Joint Infection by Matrix-assisted Laser Desorption
This is a prospective cohort study. All patients presenting for periprosthetic joint infection and requiring debridement only or resection arthroplasty will be eligible.
- Trial name
- NCT03717090
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Patient Satisfaction, Prosthetic Complication
Prosthetic Complications and Patient Satisfaction of Two Different Implant Distribution
Purpose: This clinical study aimed to evaluate patient satisfaction and prosthetic complications of different distributions of four implants supported mandibular overdentures using Stress free implant bar (SFI-Bar attachments).
- Trial name
- NCT07400380
- Testing
- four implants inserted in the mandible and distributed in quadrilateral manner and SFI-Bar had been inserted
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Amputation
Optimizing Prosthetic and Bicycle Fit for Veterans With Transtibial Amputations
Bicycling is a promising form of low-impact exercise that could prevent/treat Type 2 diabetes. However, Veterans with transtibial amputations (TTAs) may not effectively utilize bicycling for rehabilitation and exercise due to…
- Trial name
- BestBikeFit (NCT03828331)
- Testing
- Prosthetic/Bicycle Configuration
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Phantom Limb, Motor Activity
The Effects of Targeted Phantom Motor Execution on Phantom Limb Control
Lower limb amputations account for more than 85% of all amputations. In Canada, it has been reported that transtibial amputation (TTA) is the most common level of amputation.
- Conditions
- Phantom Limb, Motor Activity, Amputation Stump, Amputation
- Trial name
- NCT05247827
- Testing
- Targeted phantom limb motor execution (exercise)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Atrophic Maxillary Ridge and Mandibular Ridge
Prosthetic Rehabilitation of Thin Wiry Ridge by Ridge Splitting and Simultaneous Implants Placement
evaluates the success of prosthetic rehabilitation of thin wiry ridge and implants placed simultaneously in splitted ridge both clinically and radiographically.
- Trial name
- implant (NCT06274476)
- Testing
- implant placement
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cairo University
Amputation
Adaptive Recalibration of Prosthetic Leg Neural Control System
The purpose of this study is for transfemoral amputees to walk with an experimental robotic prosthesis. Electric signals will be measured from their muscles and used to help control an artificial leg.
- Trial name
- NCT02355912
- Testing
- Powered knee and ankle prosthesis
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Defect; Internal Prosthetic Device, Implants and Grafts, Orthopedic, Bone Graft
Clinical Application of Personal Designed 3D Printing Implants in Bone Defect Restoration
Objective: Clinical application of 3D printing implant in bone defect treatment. Study design: multicenter randomized controlled study .
- Trial name
- NCT03166917
- Testing
- 3D printing implant, autogenous bone grafting
- Where
- 3 sites in China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- fang guofang
Amputation; Traumatic, Leg, Lower
Design, Prototyping, and Testing of a Robotic Prosthetic Leg
The purpose of this graduate student research study is to test that a specifically designed and novel robotic prosthetic leg (RPL) is feasible, safe and improves symmetry, efficiency, and metabolic function during sit-to-stand…
- Trial name
- NCT04616378
- Testing
- Phase 2 Prescribed Prosthesis, Phase 2 Robotic Prosthetic Leg, Phase 3 No Prosthesis
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Prosthesis User, Amputation
Prosthetic Limb Movement Feedback for Upper and Lower Extremity Amputees
To assess the functional characteristics and utility of upper and lower limb prosthetic devices (advanced bionic and current clinical standard-of-care) that incorporate physiologically relevant touch and/or movement feedback.
- Trial name
- NCT03135847
- Testing
- Tactor
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Peri-implantitis
Crown Removal in Non-Surgical Peri-Implantitis Therapy: A Randomized Trial
The aim of this single-blind, randomized controlled clinical trial is to evaluate whether removal of the prosthetic crown influences the clinical effectiveness of non-surgical mechanical therapy in implants affected by…
- Trial name
- NCT07391202
- Testing
- Non-Surgical Peri-Implant Therapy without Crown, Non-Surgical Peri-Implant Therapy with Crown
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University