Clinical trials: Prosthetic Complications
Mammaplasty, Radiotherapy; Complications
Adjuvant Radiotherapy's Effect on One and Two Stages Prosthetic Breast Reconstruction and on Autologous Reconstruction
For patients with breast cancer subject to a mastectomy, preserving the morphology of the breast with immediate reconstruction is a crucial aspect to preserve the quality of life.
- Conditions
- Mammaplasty, Radiotherapy; Complications, Breast Implant; Complications, Transplant Failure
- Trial name
- NCT04783818
- Testing
- Adjuvant Radiotherapy
- Where
- Italy
- Volunteers
- 3,200 people
- Sponsor
- Humanitas Clinical and Research Center
Prosthetic-joint Infection, Knee Infection
Real-component vs All-cement Articulating Spacers for Periprosthetic Knee Infection
In the US, if an infection in an artificial knee joint doesn't heal with antibiotics alone, the standard treatment is a two-stage revision of the artificial knee.
- Conditions
- Prosthetic-joint Infection, Knee Infection, Arthroplasty Complications, Joint Infection
- Trial name
- NCT06293352
- Testing
- All-cement articulating spacer, Durable, real-component articulating spacer, Rigid Spacer
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Northwestern University
Prosthetic Joint Infection, Prosthetic Infection
Calprotectin in Chronic Prosthetic Joint Infection
A bacterial infection of an artificial joint is a serious complication that often requires additional surgery to exchange the arthroplasty.
- Conditions
- Prosthetic Joint Infection, Prosthetic Infection, Arthroplasty Complications
- Trial name
- NCT05060952
- Testing
- Calprotectin Lateral Flow Test
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Technical University of Munich
Incisional Hernia
Long-term Follow-up of Incisional Hernia Repaired With Intraperitoneal Mesh
The intraperitoneal repair has been proven safe for the repair of incisional hernia and is accepted, together with the subfascial or retromuscular repair as the "gold-standard" for the repair of incisional hernia.
- Trial name
- NCT00891254
- Testing
- Implant of a prosthetic mesh
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Cirujanos la Serena
Prosthetic-joint Infection, Dysbiosis
Probiotics in the Prevention of Recurrent Prosthetic Joint Infection of the Hip and Knee
Prosthetic joint infection (PJI) is one of the most devastating complications following total joint arthroplasty (TJA) of the hip and knee. Standard of care (SOC) treatment includes surgery and antimicrobials.
- Trial name
- NCT06636669
- Testing
- Probiotic, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 152 people
- Sponsor
- Boston Medical Center
Edentulous Alveolar Ridge in Mandible
SFI Bars and Milled Bars Supporting Mandibular Overdentures. Three-year Randomized Clinical Trial
The aim of this study will be to evaluate the marginal bone loss and prosthetic complications of stress-free implant (SFI) and milled bars used to assist mandibular 4-implant overdentures after 3 years
- Trial name
- NCT06620497
- Testing
- stress free implant bar, milled bar
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Fayoum University
Implant Complication
Prosthetic and Biological Complications of Implant Supported Prostheses
complications of implant retained prostheses
- Trial name
- NCT05297253
- Testing
- telescopic overdenture
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Dental Implant
Evaluation of Implants Placed in the Regular Dentist's Practice
This study is an evaluation of the implants placed in a regular dentist's practice regarding: gingiva condition stability of implant prothetic quality questionnaires for the patients
- Trial name
- NCT00286533
- Testing
- Clinical examination (implant stability, gingiva condition, etc.), Questionnaires
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Bone Metastases
Analysis of Intramedullary Nail and Prosthetic Reconstruction After Surgical Treatment of Bone Metastases of Proximal Femur
The investigators will collect data of patients treated surgically for impending or pathological fracture of the proximal femur due to bone metastases between 01/01/2000 and 31/12/2023 with IMN or THA or HHA or MegaTHA or Mega.
- Trial name
- NCT06918860
- Testing
- Analysis
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Costantino Errani
Surgical Site Infection
Antibiotic Prophylaxis in Clean Surgery. Impact on Surgical Site Infection
This is a randomized control study of antibiotic uses in clean non prosthetic surgeries. One group will be given antibiotic prophylaxis, other will receive a placebo.
- Trial name
- NCT03595852
- Testing
- Cefazolin
- Where
- Rwanda
- Volunteers
- 138 people
- Sponsor
- University of Rwanda
Atrophic Maxillary Ridge and Mandibular Ridge
Prosthetic Rehabilitation of Thin Wiry Ridge by Ridge Splitting and Simultaneous Implants Placement
evaluates the success of prosthetic rehabilitation of thin wiry ridge and implants placed simultaneously in splitted ridge both clinically and radiographically.
- Trial name
- implant (NCT06274476)
- Testing
- implant placement
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hernia, Incisional Hernia
"Nanotechnologies Applied to General Surgery and Emergency Surgery: Buckypaper as a New Fixing Method for Prosthetic Materials for the Treatment of Hernia and Incisional Hernia in Laparotomy and Laparoscopic
"Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias, diaphragmatic hernias, diaphragmatic rupture…
- Trial name
- 36P (NCT02137018)
- Testing
- PPL fixation by BP, PPL mesh
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Hip Impingement Syndrome, Prosthetic Complication
Retrospective Study on Radiological Factors Predictive of Psoas Impingement
The purpose of this study is to identify radiological factors on TC of the hip that could lead to prediction of development of symptomatic psoas impingement in patients with protruding acetabular cup after primary total hip…
- Trial name
- NCT05893823
- Testing
- Pelvis CT scan
- Where
- 2 sites in Italy
- Volunteers
- 52 people
- Sponsor
- Istituto Ortopedico Rizzoli
Edentulous Alveolar Ridge
GFRC Enhance Patient Satisfaction and Reduce Complications in Maxillary Implants With Pekkton Frameworks
This study aims to evaluate the effect of provisionalization with a glass fiber composite framework on patient satisfaction and prosthetic complications before the insertion of a definitive PEKKTON framework when used under the…
- Trial name
- NCT06581354
- Testing
- PROVISIONALIZATION
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Complete Edentulism
Prosthetic Complications in Fixed All-On-Four Prosthesis Reinforced with Poly Ether Ether Ketone (PEEK) Versus Cobalt Chromium (Co-Cr) Framework
Prosthetic complication will be measured for all-on-four fixed prosthesis in the mandibular arch in completely edentulous patients.
- Trial name
- NCT06631573
- Testing
- fixed all-on-four prosthesis reinforced with PEEK framework., Fixed all-on-four prosthesis reinforced with Co-Cr framework
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Cairo University
Complete Edentulism
Prosthetic Complications in Full-arch Screw-retained Implant Restorations Using Monolithic Zirconia Versus Titanium Frameworks: A Randomized Clinical Trial
The goal of this clinical trial is to to compare the prosthetic complication rate and Oral Health-Related Quality of Life (OHRQoL) between screw-retained monolithic zirconia frameworks and CNC-milled titanium frameworks with…
- Trial name
- NCT07657364
- Testing
- Monolithic Zirconia Prosthesis, CNC-milled titanium framework and zirconia superstructure
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Cairo University
Prosthetic Complication, Prosthesis Failure, Dental
New Stereophotogrammetry System to Capture Complete-arch Impression
Patients in need of complete arch restorations will be treated with dynamic navigation system. Once the implants are positioned, a new system of stereophotogrammetry will record the implant positions to capture a precise…
- Trial name
- NCT06745232
- Testing
- FAST MAP
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata
Edentulous Alveolar Ridge, Peri-Implantitis
Soft Tissue Response to Different Restorative Materials Used in Implant Dentistry
The goal of this clinical trial is to learn how different materials used in dental implants affect the surrounding gum tissue in adults who need dental implants.
- Conditions
- Edentulous Alveolar Ridge, Peri-Implantitis, Peri-implant Mucositis, Prosthetic Infection
- Trial name
- NCT06554041
- Testing
- Dental Crown with Titanium-Abutment, Dental Crown with PEEK (Polyetheretherketone)-Abutment, Dental Crown with Zirconia-Abutment
- Where
- Lithuania
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Knee Osteoarthritis, Joint Pain
Femoral Rotation and Patellar Positioning After TKA
Analysis of patellar positioning in the trochlear groove after TKA with and without the use of dynamic tensioner.
- Conditions
- Knee Osteoarthritis, Joint Pain, Joint Instability, Patella Disorder
- Trial name
- NCT05871112
- Testing
- Use of dynamic tensioner
- Where
- Poland
- Volunteers
- 125 people
- Sponsor
- Medical University of Warsaw
Prosthetic-joint Infection, Arthroplasty Complications
Knee Prosthetic Joint Infection Antibiotic Elution
Patients presenting with prosthetic joint infections of a total knee replacement who are treated with an antibiotic spacer will be observed prospectively for their response to treatment and antibiotic elution profiles will be…
- Trial name
- NCT06023238
- Testing
- Treatment of Chronic TKA PJI
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pittsburgh