Clinical trials: Protein Malnutrition
Aging, Appetite Loss
Effect of a Novel Protein Ingredient Combined With Oral Nutritional Supplement on Appetite in Older Adults
Reduced appetite can occur with ageing and is linked to a higher risk of undernutrition, poorer physical function and becoming frail. Strategies to increase appetite are needed to improve healthy ageing.
- Conditions
- Aging, Appetite Loss, Undernutrition
- Trial name
- NCT06478147
- Testing
- Oral Nutritional Supplement, Oral Nutritional Supplement + Whey Protein Hydrolysate, Whey Protein Hydrolysate + still water
- Where
- Ireland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University College Dublin
End-Stage Renal Disease, Malnutrition
A Plant Based High Protein Diet to Improve Nutritional Outcomes in Peritoneal Dialysis Patients
The study proposes that addition of high protein plant based diet will improve serum albumin as well serum phosphate for patients with End Stage Renal Disease (ESRD) on Dialysis.
- Trial name
- PBPD (NCT02360748)
- Testing
- Plant based high protein food items
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Ochsner Health System
Malnutrition
An Email Intervention to Prevent Iatrogenic Malnutrition in the ICU
This is a quality improvement research project evaluating if a targeted feedback email to clinicians impacts their nutrition delivery in the ICU.
- Trial name
- NCT02277535
- Testing
- Feedback/Reminder email.
- Volunteers
- 197 people
- Sponsor
- Massachusetts General Hospital
COPD
High Protein Diet and Physical Activity in COPD
COPD outpatients with severe and very severe (grade III-IV) disease at risk of malnutrition commencing rehabilitation (7-10-week physical activity program) were randomized to receive a high protein diet (≥ 25 energy percentage)…
- Trial name
- NCT04888182
- Testing
- intervention
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- Jens Rikardt Andersen
Nutrition Poor, Protein-Energy Malnutrition
Three Channel Food Concept: the Effect Meal Service on Food Intake During Hospitalization
The goal of this observational study is to assess food intake in hospitalized patients. The present study will evaluate the impact of a novel in-hospital meal concept (three channel food concept) on total energy and protein…
- Trial name
- NCT06399250
- Testing
- meal service
- Where
- Netherlands
- Volunteers
- 102 people
- Sponsor
- Maastricht University Medical Center
Hypophosphatasia
Safety and Efficacy Study of ENB-0040 in Juvenile Patients With Hypophosphatasia (HPP)
This Clinical Trial is being conducted to study Hypophosphatasia (HPP), a bone disorder caused by gene mutations or changes. These gene mutations cause low levels of an enzyme needed to harden bone.
- Trial name
- NCT00894075
- Testing
- ENB-0040
- Sponsor
- Alexion Pharmaceuticals, Inc.
Small for Gestational Age at Delivery, Low Birth Weight
Effect of a Fortified Balanced Energy-Protein Supplement on Birth Outcome and Child Growth in Houndé District, Burkina Faso.
The 2016 WHO antenatal care guidelines stated that pregnant women in undernourished populations should receive fortified balanced energy-protein (BEP) supplements to reduce the risk of stillbirth and small-for-gestational-age…
- Conditions
- Small for Gestational Age at Delivery, Low Birth Weight, Prematurity, Infant Malnutrition
- Trial name
- MISAME-3 (NCT03533712)
- Testing
- Fortified balanced energy-protein (BEP) supplement, Fe and folic acid supplement
- Where
- Burkina Faso
- Volunteers
- 1,788 people, healthy volunteers welcome
- Sponsor
- University Ghent
Malnutrition
Novel Meal Service Improves Nutritional Intake
This study aims to investigate whether a novel meal service FoodforCare (FfC), comprising 6-protein-rich meals a day following proactive advice from a nutritional assistant, improves dietary intake and patient satisfaction…
- Trial name
- NCT03195283
- Testing
- Meal service
- Volunteers
- 637 people
- Sponsor
- Radboud University Medical Center
Kwashiorkor, Marasmus
Effectiveness of Oral Antibiotics in the Treatment of Severe Acute Malnutrition
The need for oral antibiotics as part of the case management of severe acute malnutrition (SAM) in the outpatient setting has not been studied in a prospective trial.
- Trial name
- NCT01000298
- Testing
- Amoxicillin, Cefdinir
- Where
- Malawi
- Volunteers
- 2,767 people
- Sponsor
- Washington University School of Medicine
Congenital Heart Disease in Children, Post-cardiac Surgery
To Assess the Efficacy of Early Administration of Energy Enriched and Protein Enriched Formula in Post Cardiac Repair Infants: a Randomized Controlled Trial, Comparative Study
Congenital heart disease (CHD) is a public health problem, A substantial percentage of infants and toddlers with CHD undergo cardiopulmonary bypass surgery.
- Conditions
- Congenital Heart Disease in Children, Post-cardiac Surgery, Malnutrition, Infant
- Trial name
- NCT05826769
- Testing
- Energy- Protein Enriched Nutritional Formula
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Malnutrition
Effect of Energy- and Protein-rich Foods on Physiological Functions and Quality of Life in Undernourished Patients
The purpose of this study is to determine whether individualised nutritional therapy comprised of appetising, energy- and protein-rich foods can have a positive effect on physiological function and quality of life of…
- Trial name
- NCT01240031
- Testing
- Individualised nutritional therapy, Usual nutrition care
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Copenhagen
Malnutrition; Protein, Protein Malnutrition
Increase Protein Intake of Older Meal Service Clients With Readymade Protein-rich Meals and Foods
Rationale: Undernutrition risk among community-dwelling older adults in developed countries is shown to be around 24%. Increasing protein intake is a strategy that is feasible as well as efficacious to reduce undernutrition in…
- Trial name
- ConsuMEER (NCT03032237)
- Testing
- Nutritional intervention - protein-rich, Nutritional intervention - standard
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- HAN University of Applied Sciences
Nutritional Disorder, Critical Illness
The Effect of Higher Protein Dosing in Critically Ill Patients: A Multicenter Randomized Trial
The primary research question: In critically ill patients with nutrition 'risk factors', what is the effect of providing combined EN/PN to the group prescribed a higher dose (≥2.2 grams/kg/day) of protein/amino acid…
- Conditions
- Nutritional Disorder, Critical Illness, Malnutrition, Frailty
- Trial name
- EFFORTcombo (NCT04012333)
- Testing
- OLIMEL 7,6%E / PeriOLIMEL 2,5%E
- Where
- Germany
- Sponsor
- RWTH Aachen University
Hypophosphatasia
Open-Label Study of Asfotase Alfa in Infants and Children ≤ 5 Years of Age With Hypophosphatasia (HPP)
This clinical trial was conducted to study hypophosphatasia (HPP), a bone disorder caused by gene mutations or changes. These gene mutations cause low levels of an enzyme needed to harden bone.
- Trial name
- NCT01176266
- Testing
- asfotase alfa
- Where
- 23 sites in United States, Australia and 10 more
- Volunteers
- 69 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Malnutrition
COPD: Oral Nutrition Supplements vs. Energy- and Protein Dense in Between Meal Snacks.
At least one fifth of patients in European hospitals are malnourished. Malnutrition is associated with negative consequences, including higher rates of complications, longer hospital stay, impaired wound healing and increased…
- Trial name
- COPD (NCT02251496)
- Testing
- In between meals snacks (Snacks-group), Oral nutrition supplement (ONS-group)
- Where
- Iceland
- Volunteers
- 34 people
- Sponsor
- University of Iceland
Abnormal Renal Function, Malnutrition
Effects of High vs. Standard Protein Intake in Newborn Extreme Premature
Introduction: The preterm newborn of extremely low birth weight (PNELW), endures adverse nutritional conditions to mimic intrauterine growth.
- Trial name
- experimental (NCT02478086)
- Testing
- use amine acids parenteral 3.5g, use amine acids parenteral 4g
- Where
- Mexico
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Sarcopenia, Cirrhosis, Liver
LIver FRAilty Management IN Cirrhosis (LIFRAMIN)
The goal of this clinical trial is to compare food for special medical purposes (Aminolife Plus, by Piemme Pharmatech) vs. placebo in improving muscle mass and function in a cohort of cirrhotic patients.
- Conditions
- Sarcopenia, Cirrhosis, Liver, Malnutrition; Protein
- Trial name
- LIFRAMIN (NCT06573229)
- Testing
- Aminolife Plus by Piemme Pharmatech, Italy
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hospital Undernutrition, Malnutrition
INAPEN Protocol for Impact of Breakfast Improvement
Hospital undernutrition is a common health problem [1]. As a countermeasure, French hospitals have created a system of cross-function committees for feeding and nutrition called CLANs [Comité de Liaison pour l'alimentation et la…
- Conditions
- Hospital Undernutrition, Malnutrition, Nutritional Deficiency
- Trial name
- INAPEN (NCT01342861)
- Testing
- Addition of protein (milky food in the breakfast)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre Hospitalier de Meaux
Protein Malnutrition
Formative Research Study to Address Protein Intake in Children and Analysis of Breast Milk Nutrient Content in Mothers
This formative research seeks to explore the use of egg (as a potential source of protein) as nutritional supplement for young children aged 6-8 months of either sex and breast milk composition of mothers of infants under 6…
- Trial name
- NCT03140696
- Testing
- Egg Alone, Egg and ready to use supplementary food (RUSF), Egg and breast milk
- Where
- Bangladesh
- Volunteers
- 30 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Protein Malabsorption, Nutritional Deficiency
Bioavailability of Proteins From Plant Based Diets
Proteins play an important role as structural and functional components for the human body and prevent stunting. Protein quality has a great importance in meeting the nutritional needs of populations across the world throughout…
- Conditions
- Protein Malabsorption, Nutritional Deficiency, Nutritional Stunting
- Trial name
- NCT04866927
- Testing
- Use of stable isotopic dilution to assess protein digestibility from Faba bean and to evaluate amino acid bioavailability
- Where
- Morocco
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- International Atomic Energy Agency