Clinical trials: Proteinuria
Preeclampsia
Predicitve Use of Spot Urine Protein/Creatinine Ratios in Preeclampsia
The investigators intend to perform a large prospective study looking at the predictability of the random urine protein-to-creatinine ratio compared to the gold standard 24-hour urine protein collection.
- Trial name
- NCT00870428
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- MemorialCare
Pregnancy Toxemia, Hypertension
Treatment Targets for Chronic Hypertension in Pregnancy
This project is a clinical study of women with high blood pressure who become pregnant. Preeclampsia is a syndrome developing at the end of a pregnancy characterized by an abrupt rise in blood pressure (BP), blood clotting and…
- Conditions
- Pregnancy Toxemia, Hypertension, Proteinuria
- Trial name
- NCT00194974
- Testing
- methyldopa, labetalol, nifedipine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
IgA Nephropathy
Serum and Urinary sCD163 in IgA Nephropathy
IgA nephropathy is a common primary glomerular disease with a highly variable clinical course. Soluble CD163 is a marker associated with monocyte and macrophage activation and may reflect inflammatory activity in kidney disease.
- Trial name
- SCD163-IgAN (NCT07754019)
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Kidney Diseases
The Effects of Obesity and Protein Intake on the Kidney
The purpose of this study is to determine if being overweight and eating lots of protein causes separate changes in the kidney that lead to kidney disease over time.
- Trial name
- NCT00244790
- Testing
- Diet
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pre-Eclampsia, Intrauterine Growth Restriction
PEPPI Study: Identification of Women at Risk for Placental Dysfunction
The main purpose of this study is to evaluate Fetal Medicine Foundation's pre-eclampsia risk calculator using maternal characteristics, first trimester serum placental growth factor (PlGF) and mean arterial pressure (MAP) in a…
- Conditions
- Pre-Eclampsia, Intrauterine Growth Restriction, Polycystic Ovary Syndrome, Iron-deficiency
- Trial name
- NCT06115122
- Testing
- Pre-eclampsia screening program
- Where
- Finland
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Acute Renal Failure, Acute Kidney Injury
Early Diagnosis of Postoperative Acute Renal Failure-using Biomarker to Predict Outcome of Cardiac Surgery Associated Acute Kidney Injury
The purpose of this study is to determine soluble HJV could be an early diagnosis urinary biomarker of ischemia/reperfusion injury in post CPB-patients.
- Trial name
- NSARF (NCT01503710)
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Proteinuria
Bariatric Surgery and the Kidney
The purpose of the project is to study the relationship between post-bariatric surgery changes in weight and renal parameters.
- Trial name
- NCT01410994
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University
Dent Disease
Dent Disease Mutation Genotyping
This study will help the investigator determine whether certain genetic mutations, more than others, are a cause of more severe disease in Dent Disease.
- Trial name
- NCT01783795
- Testing
- Genetic Analysis
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hypertension, Proteinuria
Sympathetic Overactivity in Essential Hypertension
The primary objective of the study is whether subjects with hypertension and proteinuria display increased sympathetic nerve activity compared to hypertensive subjects without proteinuria and normotensive controls.
- Trial name
- NCT00541619
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Chronic Kidney Diseases, Proteinuria
Efficacy of On-venous Laser Irradiation of Blood on Diabetes Kidney Disease Patients
The single center, randomized, assessor- and participant-blind, controlled, cross-over on-venous laser irradiation of blood clinical trial was performed to analyze patients with DKD.
- Conditions
- Chronic Kidney Diseases, Proteinuria, Diabetes Mellitus
- Trial name
- NCT06588465
- Testing
- On-venous Laser Irradiation of Blood, low dose On-venous Laser Irradiation of Blood
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Chronic Kidney Disease stage3
Effect of Empagliflozin on Urinary Excretion of Adenosine and Osteocyte Function in Patients With Chronic Kidney Disease
Sodium-glucose cotransporter 2 (SGLT2) inhibitors are the newest class of orally drugs for the treatment of type 2 diabetes. These drugs decrease plasma glucose levels by inhibiting its reabsorption in the proximal tubules of the…
- Trial name
- NCT04961931
- Testing
- Empagliflozin 10 MG
- Where
- Poland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Healthy Volunteers
FIH Ph 1 Study of TRPC5 Channel Inhibitor GFB-887 in Healthy Subjects
The study will comprise primarily a single-ascending dose (SAD) escalation component.
- Trial name
- NCT03970122
- Testing
- GFB-887
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Goldfinch Bio, Inc.
Proteinuria, Preeclampsia
Validation of a PrCr Dipstick Diagnostic Test in Ghana
This evaluation will aim to generate a body of evidence that will determine performance characteristics of the current PrCr dipstick test and the feasibility of its use in target ANC settings.
- Trial name
- NCT03510286
- Testing
- Test-it™ PrCr Urinalysis Strips
- Where
- Ghana
- Volunteers
- 1,483 people, healthy volunteers welcome
- Sponsor
- PATH
Chronic Kidney Disease(CKD)
Effect Camostat for Kidney Protection in Chronic Kidney Disease
This clinical trial aims to evaluate the effects of Camostat Mesylate, a serine protease inhibitor, in patients with chronic kidney disease (CKD) and proteinuria.
- Trial name
- CamKid (NCT06794593)
- Testing
- Camostat Mesylate
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Nephrotic Syndrome Steroid-Dependent, Nephrotic Syndrome Steroid-Resistant
Biomarkers and Outcome Predictors of Pediatric Nephrotic Syndrome: A Genetic, Transcriptomic, and Secretome Multiomics Study
Idiopathic Nephrotic Syndrome is a rare disease of the kidneys, which typically affects children. For most affected children there is the need of a prolonged treatment with drugs reducing the activity of the immune system, also…
- Conditions
- Nephrotic Syndrome Steroid-Dependent, Nephrotic Syndrome Steroid-Resistant, Nephrotic Syndrome in Children, Glomerulonephritis
- Trial name
- PRECISE (NCT06792448)
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Blood Pressure, Albuminuria
Effect of NWT-03 on Blood Pressure
Part 2 of the study will assess the effect of 2g of NWT-03 (an egg-white protein hydrolysate) on systolic and diastolic blood pressure and flow-mediated dilation in a crossover designed study in healthy adults with mild…
- Trial name
- NCT02144740
- Testing
- NWT-03, an egg-white protein hydrolysate
- Where
- Ireland
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Newtricious R&D BV