Clinical trials: Proximal Tibial
Fracture of Tibia Proximal Plateau
Immediate Versus Late Weight Bearing After Tibial Plateau Fractures Internal Fixation
Postoperative rehabilitation for tibial plateau fracture generally involves prolonged non-weight bearing time while other protocols use partial weight-bearing and bracing before full weight-bearing is recommended at 9 to 12 weeks…
- Trial name
- NCT05502679
- Testing
- Weight bearing as tolerated, Pragmatic Exercise protocol
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Assiut University
Distal Humerus Fracture, Distal Femur Fracture
3D-printed Bone Models in Addition to CT Imaging for Intra-articular Fracture Repair
The purpose of this study is to compare the effectiveness of 3D-printed bone models in addition to CT imaging versus CT imaging alone on surgical quality and operation time for patients undergoing surgical repair of…
- Conditions
- Distal Humerus Fracture, Distal Femur Fracture, Distal Tibia Fracture, Proximal Humeral Fracture
- Trial name
- SPRINT (NCT04748016)
- Testing
- 3D printed (3DP) bone models + CT imaging, CT imaging
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Postoperative Pain
Femoral or Sciatic Nerve Block to Provide Analgesia After Proximal Tibial Osteotomy
Proximal tibial osteotomy is associated with moderate to severe postoperative pain. The proximal part of the tibia is innervated by branches from the femoral nerve anteriorly and the sciatic nerve posteriorly.
- Trial name
- NCT05728294
- Testing
- Femoral nerve block with ropivacaine 0.5%, 20 ml, Sciatic nerve block with ropivacaine 0.5%, 20 ml
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Proximal Tibia Fracture
The Efficacy and Cost Effectiveness of Preoperative and Postoperative Cryotherapy in Proximal Tibia Fractures
Consenting patients with proximal tibia fractures will be randomized to 10 degree or 21 degree cryotherapy sleeves. Time to discharge and complications will be monitored.
- Trial name
- ARCTIC CAT (NCT01104831)
- Testing
- Cryotherapy, Room temperature cuff
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Osteoarthritis, Knee
Proximal Tibial Open Wedge Osteotomy. A Clinical Prospective, Randomized RSA-trial.
In the treatment of osteoarthritis of the medial compartment of the knee, Open wedge high tibial osteotomy is a good choice of treatment for the young and active patient.
- Trial name
- NCT00319280
- Testing
- bonesubstitution (Calcibon, Iliac Crest Bonegraft, control)
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Trampoline Fracture, Tibial Fracture
Remodelling After Trampoline Fracture in Children
The anterior tilting of the proximal tibia epiphyseal plate is a radiological tool for the diagnosis of suspected trampoline fracture. The tibial fracture leads to a ventral tilting of the tibial Plateau.
- Trial name
- NCT04028908
- Testing
- radiographs in two views of the tibia
- Where
- 2 sites in Switzerland
- Volunteers
- 86 people
- Sponsor
- Peter Klimek
Ankle; Injury, Superficial, Multiple (With Foot)
Effect of Q-angle, Lateral Distal Tibial Angle and Proximal Muscle Torque on Ankle Injury
This study was undertaken to examine the effect of Q angle, lateral distal tibial angle (LDTA), and lower extremity isometric muscle torque on ankle sprain.
- Trial name
- NCT04645082
- Testing
- x-ray examination
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara Yildirim Beyazıt University
Knee Osteoarthritis
The Efficacy and Safety of Intraarticular Sodium Hyaluronate (Hyalgan) After Proximal Tibial Osteotomy in Treatment of Knee Osteoarthritis Patients
The purpose of this study is to assess the efficacy and safety of Hyalgan after proximal tibial osteotomy in treatment of knee osteoarthritis patients.
- Trial name
- NCT01267214
- Testing
- Sodium Hyaluronate (Hyalgan), Osteotomy alone
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- TRB Chemedica
Proximal Tibia Fracture, Tibial Shaft Fracture
MY01 Pressure Monitoring in Adolescent Tibia Fractures
The goal of this clinical trial is to learn more about anterior leg compartment pressures in adolescents who have sustained tibia fractures.
- Conditions
- Proximal Tibia Fracture, Tibial Shaft Fracture, Acute Compartment Syndrome
- Trial name
- NCT07674043
- Testing
- Continuous Compartmental Pressure Monitor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
Humerus Fracture, Femur Fracture
Evaluation of Handling and Possible Complications Related to the Newly Developed Angular Stable Locking System (ASLS)
In many cases, the existing locking bolts and screws in intramedullary nails do not provide sufficient stability. Due to the play between screw and nail, the reduction can be lost and the instability can result in malunions…
- Conditions
- Humerus Fracture, Femur Fracture, Tibia Fracture
- Trial name
- ASLS-Pre (NCT00793637)
- Where
- 4 sites in Austria, Germany
- Volunteers
- 30 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Femoral Neck Fractures, Intertrochanteric Fractures
Opioid-Free Pain Treatment in Trauma Patients
Analgesic drug study that will compare pain outcomes of opioid analgesia and opioid-free analgesia in post-operative orthopedic patients.
- Conditions
- Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture
- Trial name
- NCT06078371
- Testing
- Opioid-free pain treatment
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Kansas Medical Center
Proximal or Diaphyseal Humerus Fracture, Diaphyseal or Distal Femur Fracture
Observational Patient Registry of the Dynamic Locking Screws
The purpose of this multi-center patient registry is to obtain first clinical results and to assess short and mid-term clinical outcome data of patients treated with DLS.
- Conditions
- Proximal or Diaphyseal Humerus Fracture, Diaphyseal or Distal Femur Fracture, Diaphyseal, Distal or Proximal Tibia Fracture
- Trial name
- DLS (NCT02656628)
- Testing
- Dynamic Locking Screw 3.7mm and 5.0mm
- Where
- Australia
- Sponsor
- Synthes GmbH
Intraosseous Access, Resuscitation
Trial Comparing Proximal Tibia and Proximal Humerus Infusion Rates Using the NIO Intraosseous Device
The investigators sought to compare the intraosseous access success rates of the proximal tibia and the proximal humerus using new Intraosseous access device "NIO" in an adult cadaver model during simulated resuscitation.
- Trial name
- IOACS (NCT02700867)
- Testing
- NIO
- Where
- Poland
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Arthritis (Knee), Varus Knee
Precision of Pacient-specific Instrumented Open Wedge High Tibial Osteotomy vs Conventional Technicque
This study is a randomized clinical trial that will compare two surgical techniques for patients with knee osteoarthritis and varus deformity who are candidates for medial opening wedge high tibial osteotomy.
- Trial name
- AMBE_OR (NCT07212777)
- Testing
- Medial Open Wedge Hight Tibial Osteotomy using patient-specific instrumentation, Medial Open Wedge Hight Tibial Osteotomy using conventional surgery techniques
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Malaga
Distal Femoral, Proximal Tibial
Subchondral Perfusion Mapping Using Indocyanin Green Laser
Laser Angiography using indocyanin green (ICG) is a relatively new technique and has been utilized to assess the viability of soft tissue, most prominently in the general surgery and plastic surgery literature.
- Conditions
- Distal Femoral, Proximal Tibial, Knee Surgery
- Trial name
- ICG (NCT02918383)
- Testing
- Indocyanin Green Dye (ICG)
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Tibia Vara in Children
Short-term Outcomes of High Tibial Osteotomy Using a Plate Versus a Plate With an Interbody Fusion Cage in Adolescent Tibia Vara : a Comparative Study
Tibia vara is a progressive angular deformity of the lower limb centered at the proximal tibial physis, producing a characteristic bowing of the leg.
- Trial name
- NCT07400705
- Testing
- high tibial osteotomy using interbody fusion cage
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Sohag University
Cancer of the Bone, Limb Salvage
Tranexamic Acid Use to Reduce Blood Transfusion in Pediatric Cancer Patients Undergoing Limb Salvage Procedure
This is a randomized double-blind control trial evaluating the use Tranexamic acid (TXA) to decrease blood loss and transfusion requirements in pediatric and young adult cancer patients undergoing a limb salvage procedure that…
- Trial name
- NCT04410042
- Testing
- Tranexamic Acid, 0.9% sodium chloride
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- St. Jude Children's Research Hospital
Periarticular Bone Defect, Proximal Humerus Fracture
Magnesium Alloy Scaffold With Controlled Degradation for Periarticular Bone Defects
This prospective, multi-center, randomized controlled clinical trial is designed to evaluate the effectiveness and safety of a biodegradable magnesium alloy scaffold with controlled degradation for the treatment of periarticular…
- Conditions
- Periarticular Bone Defect, Proximal Humerus Fracture, Distal Radius Fracture, Tibial Plateau Fracture
- Trial name
- MgScaf-PBD (NCT07906730)
- Testing
- Magnesium Alloy Scaffold, Calcium Sulfate Bone Graft Substitute
- Where
- 4 sites in China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Peripheral Arterial Disease
Post-Market Evaluation of Active Thrombectomy and Proximal Aspiration During Lower Extremity Tibial Interventions
Post-Market Evaluation of Active Thrombectomy and Proximal Aspiration during Lower Extremity Tibial Interventions
- Trial name
- Protexus 1 (NCT06929832)
- Volunteers
- 20 people
- Sponsor
- Protexa Endovascular, Inc.
Fracture Non Union, Fracture Healing
Prospective Validation Study of the CD8+TEMRA Cells As a Prognostic Biomarker of Healing Outcome After Fracture
In approx. 10-15% of all fracture patients, there is a prolonged healing time or even a complete absence of fracture healing (non-union).
- Conditions
- Fracture Non Union, Fracture Healing, Long Bone Delayed-Union Fracture, Humerus Shaft Fracture
- Trial name
- BioBone (NCT06658379)
- Testing
- CD8+TEMRA
- Where
- 7 sites in Germany
- Volunteers
- 640 people
- Sponsor
- Charite University, Berlin, Germany