Clinical trials: Pruritis
Pain, Vertigo
Efficacy of Extended-release, Once Daily Tramadol for Post Operative Analgesia in Shoulder Arthroscopy
The investigators hypothesize that the use of tramadol will reduce pain and analgesic consumption after arthroscopic shoulder surgery.
- Conditions
- Pain, Vertigo, Nausea, Pruritus
- Trial name
- NCT02247648
- Testing
- tramadol
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lidocaine, Itch
Evaluation of the Effect Induced by Repeated Administration of Topical Local Anaesthetic (EMLA) on Itch
In this experiment, the investigators would like to study if the repeated application of local cuaneous anaesthetic EMLA cream will reduce itch induced by small needles from the plant mucuna pruriens (also known as cowhage) and…
- Trial name
- NCT04076865
- Testing
- EMLA (lidocaine) +Itch (Histamine and cowhage)
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Pruritus
Study of Effectiveness of Mexyn-A
Atomised Methoxymethane-in-Aqua (MEXYN-A) a new topical self-chilled, non-steroidal, non-flammable, pressurised spray which embodies in one simultaneous application, most of the currently recognised and effective chemical…
- Trial name
- Mexyn-A (NCT00568204)
- Testing
- Mexyn-A
- Where
- Egypt
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Evangelical Synod Medical Centre
Inflammation, Pruritus
L-menthol as a Topical Counter-irritant to TRPA1-induced Neurogenic Inflammation and Pain
The aim of this study is to quantitatively characterize the effects of L-menthol as a topical counter-irritant on cutaneous pain and hyperalgesia provoked by topical application of the TRPA1-agonist trans-cinnamaldehyde (CA) in…
- Conditions
- Inflammation, Pruritus, Hyperalgesia
- Trial name
- NCT02653703
- Testing
- Topical L-menthol 40%, Vehicle, topical ethanol 96%
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Itch
Inhibition of Non-histaminergic Pruritus Applied Using 3 Different Pruritogens
With this experiment, we want to use to investigate whether repeated application of EMLA cream as a tool to modulate non-histaminergic itching, which is produced using small needles from the plant mucuna pruriens (it is known…
- Trial name
- NCT04858360
- Testing
- Emla 1 hour, EMLA 3 hours, Vehicle cream for 1 hour
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Atopic Dermatitis, Psoriasis Vulgaris
Blue Light in the Treatment of Inflammatory Skin Diseases
The goal of this clinical trial is to assess the effectiveness of full-body blue light irradiations in the treatment of inflammatory skin diseases (atopic dermatitis, psoriasis, eczema) and chronic pruritus in adult and pediatric…
- Conditions
- Atopic Dermatitis, Psoriasis Vulgaris, Eczema, Pruritus
- Trial name
- NCT06516783
- Testing
- Full Body Blue GEN 1.0 device
- Where
- Poland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Dermatitis, Atopic, Pruritus
Study to Evaluate ASN008 Topical Gel (TG)
This is an ascending dose escalation study to test the safety, tolerability and preliminary efficacy of ASN008 TG in first-in-human subjects
- Conditions
- Dermatitis, Atopic, Pruritus, Dermatitis Eczema
- Trial name
- NCT03798561
- Testing
- ASN008 TG
- Where
- 5 sites in United States, Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Asana BioSciences
Onychomycosis, Tinea Pedis
Spread of Dermatophytes Among Families
The objective is to demonstrate person-to-person spread of dermatophytes of the skin and nails among family members, as measured by fungal culture and DNA typing of the dermatophytes isolated.
- Trial name
- NCT00233493
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Seborrheic Dermatitis
Neurobiology of the Scalp in Seborrheic Dermatitis
Seborrheic dermatitis is a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp or inside the ear.
- Trial name
- NCT02349854
- Testing
- Biopsy
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boston University
Pruritus
Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine
The purpose of this study is to examine the antipruritic efficacy of topical ketamine, amitriptyline, lidocaine, and a tri-combination of ketamine, amitriptyline and lidocaine (hereafter referred to as "KeAmLi") using…
- Trial name
- NCT03096444
- Testing
- Ketamine Hydrochloride, Amitriptyline Hydrochloride, Lidocaine Hydrochloride
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Gil Yosipovitch
Allergic Rhinitis, Urticaria
PK Comparisons of Bepotastine Besilate 10 mg and Bepotastine Salicylate 9.64 mg
To compare the relative bioavailability and pharmacokinetic characteristics of a newly developed bepotastine formulation, bepotastine salicylate, with a conventional formulation, bepotastine besilate, in healthy subjects with a…
- Conditions
- Allergic Rhinitis, Urticaria, Pruritus
- Trial name
- NCT01897428
- Testing
- Test-Bepotastine salicylate 9.64 mg, Reference-bepotastine besilate 10 mg
- Where
- South Korea
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Pruritus, Pregnancy Related
Treatment of Pruritus With Intramuscular Promethazine
Neuraxial narcotics are commonly used in obstetric patients for cesarean delivery to help with pain control over the first 24 hours after the surgery.
- Trial name
- NCT04805073
- Testing
- Promethazine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Florida
Skin Itching, Chronic Urticaria
Association of Thyroid Autoimmunity and Chronic Urticaria
Increase prevalence of thyroid autoimmunity is found in patients with chronic urticaria. About 5-34% of chronic urticaria patients is associated with the presence of thyroid autoimmunity who are euthyroid status whereas 5-10% of…
- Trial name
- NCT00737451
- Testing
- blood sampling
- Where
- Taiwan
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Pain, Acute, Itch
The Effect of Halophyte-based Cream on Pain and Itch
In this study the investigators wish to investigate whether halophyte-based cream applied to the skin can reduce itch applied by means of small needles from the plant mucuna pruriens (also called cowhage) or by histamine (an…
- Trial name
- NCT04635254
- Testing
- Halophites-based cream 24 hours, Halophites-based cream 48 hours, Vehicle cream 24 hours
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Athlete Foot
The Effect Of Plyometric Training On Balance And Proprioception In Different Branches Athletes
The aim of this study is to investigate the effect of plyometric training on balance and proprioception in athletes in different branches. 54 athletes participated in the study.
- Trial name
- Plyometric (NCT05754463)
- Testing
- The effect of plyometric training on balance and proprioception in athletes in different branches
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- mustafa gulsen
Ankle Injuries, Instability; Ankle (Ligaments) (Old Injury)
A Morphological Study in Volleyball Athletes With Cronic Ankle Instability
The former purpose of this study to investigate the effect of transverse abdominis, lumbar multifidus, vastus lateralis, lateral gastrocnemius, anterior talofibular ligament of morphology on explosive power and balance…
- Conditions
- Ankle Injuries, Instability; Ankle (Ligaments) (Old Injury), Radiological Devices Associated With Adverse Incidents, Diagnostic and Monitoring Devices, Athlete Foot
- Trial name
- NCT05746663
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dry Eye, Eye Fatigue
A Randomized Controlled Trial to Evaluate the Safety and Efficacy of an Oral Supplement in Supporting Vision and Eye Health
This is a 4-week virtual randomized, triple-blinded, placebo-controlled clinical trial evaluating the safety and efficacy of Eye Empower, an oral supplement, in adults aged 45 or older experiencing dry eyes, irritation, and…
- Trial name
- NCT07123584
- Testing
- Eye Empower
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bio Nature Health
Pruritus
Influence of H1-antihistamines on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.
In order to validate the accuracy and reliability of the histamine skin prick model for histaminergic itch and vasodilation, the dermal blood flow response induced by a histamine skin prick will be evaluated after the…
- Trial name
- NCT04399525
- Testing
- Desloratadine Single Dose, Levocetirizine Single Dose, Desloratadine Fourfold Dose
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Acupuncture, Morphine Induced Pruritis
Efficacy of Acupuncture for Prophylaxis of Intrathecal Morphine Induced Pruritis in Patients Undergoing Caesarean Delivery
Intrathecal morphine is commonly used for pain relief in caesarean delivery. Side effects such as itch (pruritis) and nausea \& vomiting are common and have been shown to be the most common cause for dissatisfaction.
- Trial name
- NCT01283477
- Testing
- ACUPUNCTURE AT LI11
- Where
- Ireland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Letterkenny General Hospital
Itch, Thermal Stimulation
A Mechanistic Evaluation of the Interactions Between Thermoceptive and Pruriceptive Sensory Processing
The purpose of this human experimental study is to evaluate the pattern of itch intensity over time in response to strong, short-term heat stimulation in two different models of histamine and cowhage-induced itch.
- Conditions
- Itch, Thermal Stimulation, Histamine, Cowhage
- Trial name
- NCT03576053
- Testing
- Lidocaine, Histamine, Cowhage
- Where
- Denmark
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Aalborg University