Clinical trials: Pseudomelia
Phantom Pain Following Amputation of Lower Limb, Amputation
Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment
After amputation of an arm or leg, up to 90% of subjects experience a "phantom limb", a phenomenon characterized by persistent feelings of the missing limb.
- Trial name
- PLP Home-Based (NCT07044323)
- Testing
- Active Virtual Reality Treatment
- Where
- 3 sites in United States
- Volunteers
- 44 people
- Sponsor
- Albert Einstein Healthcare Network
Phantom Pain Following Amputation of Lower Limb
the Influence of Virtual Reality Approach on Phantom Pain in Trans Tibial Amputation
1. To investigate the effect of Virtual reality (VR) on phantom limb pain in trans tibial amputation. 2. To investigate the effect of Virtual reality (VR) on lower limb Function in trans tibial amputation.
- Trial name
- NCT06262503
- Testing
- Virtual Reality, Transcutaneous Electrical Nerve Stimulation (TENS), Mirroring Therapy
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Phantom Limb Pain, Residual Limbs
Focused Ultrasound Treatment of Stump Neuromas for the Relief of Chronic Post-Amputation Neuropathic Pain
AIM: To provide initial information on the efficacy (pain reduction) and safety of focused ultrasound surgery for the ablation of stump neuromas in amputees with chronic neuropathic pain.
- Conditions
- Phantom Limb Pain, Residual Limbs, Amputation
- Trial name
- NCT03255395
- Testing
- Magnetic resonance-guided focused ultrasound
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Rambam Health Care Campus
Phantom Limb Pain
Massage Therapy for Phantom Limb Pain: Feasibility and Pilot Study
Massage therapy is a treatment self-reported by those with phantom limb pain (PLP) as moderately to extremely effective, but no research to date has been specifically designed to examine such efficacy or effectiveness in this…
- Trial name
- NCT03372668
- Testing
- massage therapy combined with components of mirror therapy
- Volunteers
- 3 people
- Sponsor
- Indiana University
Amputation
Targeted Muscle Reinnervation Study (TMR)
The purpose of this study is to examine the effect of targeted muscle reinnervation on the outcomes of amputees at a level 1 trauma center.
- Trial name
- TMR (NCT05408520)
- Testing
- Targeted Muscle Reinnervation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arizona
Phantom Limb
Study to Identify the Genetic Variations Associated With Phantom Limb Pain
The purpose of this study is to determine if there is a genetic component to phantom limb pain. DNA will be analyzed for single nucleotide polymorphisms (SNPs) between the control and phantom limb pain group.
- Trial name
- NCT01462448
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 726 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Phantom Limb Pain, Amputation, Traumatic
Optimizing Rehabilitation for Phantom Limb Pain Using Mirror Therapy and Transcranial Direct Current Stimulation (tDCS)
This is a two-site study that explores the effects of mirror therapy and transcranial Direct Current Stimulation (tDCS, Soterix ©) in a randomized factorial controlled trial in which patients will be assigned to one of four…
- Trial name
- NCT02487966
- Testing
- transcranial Direct Current Stimulation (tDCS): active (Soterix ©), Mirror Therapy: active
- Where
- 2 sites in United States, Brazil
- Volunteers
- 132 people
- Sponsor
- Spaulding Rehabilitation Hospital
Phantom Limb Pain
Myoelectrically Controlled Augmented Reality and Gaming for the Treatment of Phantom Limb Pain
The goal of the clinical investigation is to reduce phantom limb pain (PLP), painful condition affecting 70% of amputees, so as to improve these patients' quality of life.
- Trial name
- NCT02281539
- Testing
- Neuromotus
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Integrum
Neuropathic Pain, Facial Pain
Motor Cortex Stimulation for Chronic Neuropathic Pain
The purpose of this study is to evaluate the efficacy of cortical stimulation (CS) as an adjunctive treatment for chronic neuropathic pain.
- Conditions
- Neuropathic Pain, Facial Pain, Post-stroke Pain, Brachial Plexus Avulsion
- Trial name
- NCT01554332
- Testing
- Motor Cortex Stimulation using SJM EonC Stimulator
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Abbott Medical Devices
Phantom Limb Pain
Psilocybin-assisted Therapy for Phantom Limb Pain
This double-blind placebo-controlled pilot study seeks to investigate whether psilocybin can be safely administered to people with chronic phantom limb pain (PLP) in a supportive setting with close follow-up, and its effects on…
- Trial name
- NCT05224336
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Diego
Neuropathic Pain
Brain Computer Interface and Virtual Reality (BCI-VR) for Pain Treatment
Pilot Interventional study with minimal risks and constraints, prospective, monocentric. Safety and Efficacity evaluation of a Novel Medical Device.
- Trial name
- GHOST (NCT03889353)
- Testing
- BCI sessions
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Nantes University Hospital
Phantom Limb Pain, Amputation
TITAN Trial: Reducing Phantom Limb Pain in People with Amputations
The goal of this clinical trial is to investigate the effectiveness of two rehabilitation programs for individuals who have undergone amputations and are experiencing phantom limb pain.
- Trial name
- TITAN (NCT06167330)
- Testing
- Progressive rehabilitation program, Stimulation devices
- Where
- Australia
- Volunteers
- 208 people
- Sponsor
- Neuroscience Research Australia
Phantom Limb Pain
Optimized Perioperative Analgesia Reduces the Prevalence and the Intensity of Phantom Pain in Lower Limb Amputation
Severe pre-amputation pain is associated with phantom pain development, and phantom pain models assign major importance to central and peripheral nervous system changes related to pre-amputation pain.
- Trial name
- NCT00443404
- Testing
- perioperative epidural catheter
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Patras
Residual Limb Pain, Post-Traumatic Limb Pain
Kinematics-Based Prediction of Chronic Pain After Combat-Related Extremity Trauma
Combat-related extremity trauma frequently results in persistent pain, including neuropathic, residual limb, and phantom limb pain.
- Conditions
- Residual Limb Pain, Post-Traumatic Limb Pain, Extremity Trauma, Combat-Related Limb Injury
- Trial name
- KIN-LIMB (NCT07432685)
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Phantom Limb Pain
Phantom Limb Pain: Efficacy of Non-invasive Sensory Feedback Through the Prosthesis
Amputation of a limb may result from trauma or surgical intervention. The amputation traumatically alters the body image, but often leaves sensations that refer to the missing body part.
- Trial name
- EPIONE (NCT02589080)
- Testing
- Non-invasive sensory feedback
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Lund University Hospital
Phantom Limb Pain
Assessing the Feasibility of a Virtual Reality Intervention for Phantom Pain Immediately Following Lower Limb Amputation
The goal of this observational study is to see whether a new virtual reality (VR) program meant to treat phantom limb pain (PLP) is feasible to people immediately following lower limb amputation.
- Trial name
- NCT06638918
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Amputation, Phantom Limb Pain
Neuromodulation in Lower Limb Amputees
The goal of this study is to investigate the role of transcutaneous spinal cord stimulation on spinal cord excitability in lower limb amputees.
- Conditions
- Amputation, Phantom Limb Pain, Hoffman's Reflex
- Trial name
- NCT04543786
- Testing
- Transcutaneous spinal cord stimulation
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- University of Pittsburgh
Neuroma, Phantom Limb Pain After Amputation
Ultrasound-Guided Platelet-Rich Plasma Versus Local Anesthetic Injection for Chronic Neuroma Pain After Combat-Related Amputation
Patients with combat-related amputations frequently experience chronic neuroma pain that may interfere with rehabilitation, prosthesis use, mobility, sleep, and quality of life.
- Conditions
- Neuroma, Phantom Limb Pain After Amputation, Stump Pain, Platelet-rich Plasma (PRP)
- Trial name
- PRP-NEUROMA (NCT07624890)
- Testing
- Platelet-Rich Plasma (PRP) Injections, Local Anesthetic Injection
- Where
- 2 sites in Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy