Clinical trials: Pseudomelia
Phantom Limb, Leg Amputation
Leg Amputation and Continuous Sciatic Nerve Block
Analgesia following leg amputation is based on morphine administration. For elderly patients of ASA physical status 2 or 3, morphine sparing is possible when perinervous block techniques are used.
- Trial name
- CAPDAF (NCT00427947)
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Bordeaux
Symptomatic Neuroma, Phantom Limb Pain After Amputation
Evaluation of RPNI for Symptomatic Neuromas in Lower Limb Amputees
This prospective, observational cohort study evaluates the long-term outcomes of Regenerative Peripheral Nerve Interface (RPNI) surgery in patients with major lower extremity amputations suffering from symptomatic neuromas.
- Conditions
- Symptomatic Neuroma, Phantom Limb Pain After Amputation, Residual Limb Pain, Neuropathic Pain
- Trial name
- RPNI-AMPUTEE (NCT07420192)
- Testing
- Regenerative Peripheral Nerve Interface (RPNI) Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Saglik Bilimleri Universitesi
Chronic Phantom Limb Pain
Open Label Study of Duloxetine for the Treatment of Phantom Limb Pain
This is a study to assess the possible benefit of duloxetine in the treatment of chronic phantom limb pain.
- Trial name
- NCT00425230
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Phantom Limb Syndrome With Pain
Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.
Must be living Within a 50 mile radius of our study sites: Bay Area, Los Angeles, Albuquerque, Sacramento, Los Angeles An anecdotal report with administration of ketamine in a non-clinical setting providing and sustained…
- Trial name
- PLP (NCT07276542)
- Testing
- IM ketamine in dose finding and then continuation
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- The Ketamine Research Foundation
Neuralgia
P4 (Pregabalin for Peripheral Posttraumatic Pain)
To evaluate the efficacy of pregabalin compared to placebo in the treatment of posttraumatic peripheral neuropathic pain
- Trial name
- P4 (NCT00292188)
- Testing
- pregabalin
- Where
- 44 sites in Belgium, Canada and 9 more
- Volunteers
- 255 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Limb Pain, Phantom, Residual Limbs Pain
Pain and Disability Outcomes in Post Amputation Patients
The objective of this study is to evaluate efficacy of varied medical and procedural therapies used to treat pain after surgical amputation of a limb.
- Conditions
- Limb Pain, Phantom, Residual Limbs Pain, Disability Physical
- Trial name
- NCT05716321
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Milton S. Hershey Medical Center
Pain, Amputation
Sciatic Block in Contralateral Limb Phantom and Residual Limb Pain
Participants with chronic, refractory phantom limb pain (PLP) or residual limb pain (RLP) for more than 6 months will be enrolled in this clinical trial.
- Trial name
- NCT05046639
- Testing
- 10 mL 2% lidocaine, 10 mL preservative free saline
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Northwestern University
Pain, Neuropathic, Complex Regional Pain Syndromes
Modulating Neuropathic Pain With Transcranial Direct Current Stimulation
This study will examine whether a form of non-invasive brain stimulation can help reduce pain in people with persistent neuropathic pain.
- Conditions
- Pain, Neuropathic, Complex Regional Pain Syndromes, Phantom Limb Pain, Spinal Cord Injuries
- Trial name
- NCT04581525
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Susan McDowell
Complex Regional Pain Syndromes, Postherpetic Neuralgia
The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Paravertebral Block
The purpose of this study is to investigate the effect of ultrasound-guided thoracic paravertebral block (TPVB) when performing sympathetic block for upper limb pain control.
- Conditions
- Complex Regional Pain Syndromes, Postherpetic Neuralgia, Phantom Limb Pain, Chronic Post Surgical Pain
- Trial name
- NCT04876989
- Testing
- US-SGB, US-TPVB
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University
Phantom Limb Pain
Home-based Rehabilitation Intervention for Phantom Limb Pain in Veterans With Lower Limb Amputations
Nearly 60-85% of Veterans with amputations experience pain at the location of the amputated limb called phantom limb pain (PLP).
- Trial name
- NCT06106984
- Testing
- Graded motor imagery mobile app
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Limb Pain, Phantom
A Study of Contralateral Limb Block
This research is being done to determine if an anesthetic like Lidocaine, may be effective when injected around the sciatic nerve of the intact limb in patients with limb loss pain on the contralateral side.
- Trial name
- NCT06045936
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Phantom Limb Pain
Incidence and Factors Affecting the Development and Outcome of Phantom Limb Pain (PLP) - A Single-centre Prospective Cohort Study.
Phantom limb pain (PLP), defined as pain felt in the missing portion of the amputated limb following amputation, occurs in a significant percentage of patients who undergo limb amputation and it is among the most difficult…
- Trial name
- NCT05005481
- Testing
- NIL intervention
- Where
- Singapore
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Phantom Limb Pain (PLP), Primary/Secondary Scar Hyperalgesia
A Trial of Lidocaine Patch for Lower Limb Amputation Pain
Phantom limb pain (PLP) and scar hyperalgesia (SH) are frequent problems after amputation; in particular most persons who undergo limb amputation will experience phantom pain.
- Trial name
- NCT02696720
- Testing
- Lidocaine
- Where
- 2 sites in Belgium
- Sponsor
- Brugmann University Hospital
Phantom Limb Pain
Sensory Retraining for Phantom Limb Pain
86-87% of people who have had an amputation still feel pain in the limb that has been amputated - Phantom limb pain (PLP). Sensory retraining is a form of treatment for PLP where a special form of electrical stimulation is…
- Trial name
- PHANTOM RELIEF (NCT04103983)
- Testing
- Sensory retraining device
- Where
- United Kingdom
- Volunteers
- 109 people
- Sponsor
- Teesside University
Phantom Pain
Neural Bases of Phantom Pain After Amputation
The amputation of a limb results in chronic pain associated with the lost limb in the majority of patients, which persists over time.
- Trial name
- Phantom limb (NCT05545358)
- Testing
- Questionnaires, Brain and Spinal Cord functional Magnetic Resonance Imaging, Proprioceptive training
- Volunteers
- 75 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Pain, Phantom, Pain, Neuropathic
Valproic Acid for the Prevention of Post-Amputation Pain
The objectives of this study are, to test the effectiveness of Valproic Acid (VPA) in the prevention of chronic neuropathic and post-amputation pain, as well as to further define the underlying inflammatory and epigenetic…
- Trial name
- NCT01928849
- Testing
- Valproic Acid, Cherry Syrup
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- Duke University
Phantom Limb Pain, Chronic Pain
Prevention of Phantom Limb Pain After Transtibial Amputation
Phantom limb pain following amputation is a major problem. Current evidence how to best prevent phantom limb pain is equivocal because previous trials have included small numbers of patients, and tested heterogeneous patient…
- Conditions
- Phantom Limb Pain, Chronic Pain, Prevention
- Trial name
- PLATA (NCT01626755)
- Testing
- Sciatic name block
- Where
- 9 sites in United States, Austria and 3 more
- Volunteers
- 12 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Phantom Limb Pain
Graded Motor Imagery in Phantom Limb Pain (GraMI Protocol)
The International Association for the Study of Pain defines phantom limb pain (PLP) as that pain referred to a part of the body that has been previously removed as if it were still present.
- Trial name
- GraMI (NCT05083611)
- Testing
- GraMI
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- University of Vic - Central University of Catalonia
Phantom Limb Pain
Pre-emptive Sciatic Bloc to Prevent Lower Limb Phantom Pain
Phantom limb pain is a complication of amputation. Although pre-empitve epidural analgesia was once thought to prevent such a com plication, recent studies did not demonstrate this.
- Trial name
- NCT00528463
- Testing
- sciatic nerve block
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Université de Sherbrooke
Neuropathic Pain, Phantom Limb Pain
Mindful SensoriMotor Therapy With Brain Modulation in Highly Impaired Extremities
Brief summary: This single-arm, pilot clinical investigation aims to evaluate Mindful SensoriMotor Therapy (MSMT) enhanced with brain modulation as a treatment of pain due to sensorimotor impairment, such as Phantom Limb Pain…
- Trial name
- NCT04897425
- Testing
- Mindful SensoriMotor Therapy Enhanced with Brain Modulation
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Chalmers University of Technology